Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD13594a TUM_PILEUP_MUTS_PD13594a Pileup_MtAlpct_PD13594a ID.2 DEPTH_PD13594c TUM_PILEUP_MUTS_PD13594c Pileup_MtAlpct_PD13594c ID.3 DEPTH_PD13594d TUM_PILEUP_MUTS_PD13594d Pileup_MtAlpct_PD13594d ID.4 DEPTH_PD13594e TUM_PILEUP_MUTS_PD13594e Pileup_MtAlpct_PD13594e ID.5 DEPTH_PD13594f TUM_PILEUP_MUTS_PD13594f Pileup_MtAlpct_PD13594f ID.6 DEPTH_PD13594g TUM_PILEUP_MUTS_PD13594g Pileup_MtAlpct_PD13594g ID.7 DEPTH_PD13594h TUM_PILEUP_MUTS_PD13594h Pileup_MtAlpct_PD13594h ID.8 DEPTH_PD13594i TUM_PILEUP_MUTS_PD13594i Pileup_MtAlpct_PD13594i ID.9 DEPTH_PD13594j TUM_PILEUP_MUTS_PD13594j Pileup_MtAlpct_PD13594j PD13594b 11 32450080 G C WT1 CCDS7878.2 r.1017c>g c.732C>G p.F244L Sub missense 2 UNKNOWN_OTHER UNKNOWN 76 pS 2 2 3 1 76 2 YES NO WT1:p.F244L 297 0 0 11:32450080 167 3 1.8 11:32450080 237 0 0 11:32450080 174 0 0 11:32450080 211 1 0.5 11:32450080 483 24 5 11:32450080 295 12 4.1 11:32450080 229 6 2.6 11:32450080 228 5 2.2 PD13594b 4 153332930 C T FBXW7 CCDS3777.1 r.175g>a c.26G>A p.G9D Sub missense 2 UNKNOWN_OTHER UNKNOWN 76 pS 2 2 3 1 76 2 YES NO FBXW7:p.G9D 63 0 0 4:153332930 94 0 0 4:153332930 99 0 0 4:153332930 99 0 0 4:153332930 111 0 0 4:153332930 24 4 16.7 4:153332930 90 0 0 4:153332930 101 0 0 4:153332930 103 0 0 PD13594b X 70345320 G C MED12 CCDS43970.1 r.2378g>c c.2346G>C p.L782L Sub silent 2 SILENT SILENT 76 pS 2 2 3 1 76 2 YES NO MED12:p.L782L 145 2 1.4 X:70345320 130 13 10 X:70345320 162 1 0.6 X:70345320 125 7 5.6 X:70345320 156 5 3.2 X:70345320 184 21 11.4 X:70345320 112 12 10.7 X:70345320 169 17 10.1 X:70345320 151 5 3.3 PD13594b 3 47162114 C T SETD2 CCDS2749.2 r.4055g>a c.4012G>A p.E1338K Sub missense 1 UNKNOWN_BCA UNKNOWN 76 pS 2 2 3 1 76 2 YES NO SETD2:p.E1338K 97 1 1 3:47162114 180 16 8.9 3:47162114 128 0 0 3:47162114 223 6 2.7 3:47162114 185 12 6.5 3:47162114 48 6 12.5 3:47162114 194 19 9.8 3:47162114 228 22 9.6 3:47162114 232 11 4.7 PD13594b 17 7578268 A C TP53 CCDS11118.1 r.771u>g c.581T>G p.L194R Sub missense 1 ONCOGENIC_BCA_GENE ONCOGENIC 76 pS 2 2 3 1 76 2 YES NO TP53:p.L194R 275 9 3.3 17:7578268 197 18 9.1 17:7578268 320 0 0 17:7578268 220 8 3.6 17:7578268 242 22 9.1 17:7578268 336 57 17 17:7578268 247 26 10.5 17:7578268 209 27 12.9 17:7578268 309 25 8.1