Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14705a TUM_PILEUP_MUTS_PD14705a Pileup_MtAlpct_PD14705a ID.2 DEPTH_PD14705c TUM_PILEUP_MUTS_PD14705c Pileup_MtAlpct_PD14705c ID.3 DEPTH_PD14705d TUM_PILEUP_MUTS_PD14705d Pileup_MtAlpct_PD14705d ID.4 DEPTH_PD14705e TUM_PILEUP_MUTS_PD14705e Pileup_MtAlpct_PD14705e ID.5 DEPTH_PD14705f TUM_PILEUP_MUTS_PD14705f Pileup_MtAlpct_PD14705f ID.6 DEPTH_PD14705g TUM_PILEUP_MUTS_PD14705g Pileup_MtAlpct_PD14705g ID.7 DEPTH_PD14705h TUM_PILEUP_MUTS_PD14705h Pileup_MtAlpct_PD14705h ID.8 DEPTH_PD14705i TUM_PILEUP_MUTS_PD14705i Pileup_MtAlpct_PD14705i ID.9 DEPTH_PD14705j TUM_PILEUP_MUTS_PD14705j Pileup_MtAlpct_PD14705j ID.10 DEPTH_PD14705k TUM_PILEUP_MUTS_PD14705k Pileup_MtAlpct_PD14705k PD14705b 8 139606286 C G COL22A1 CCDS6376.1 r.5036g>c c.4589G>C p.G1530A Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 89 pS 4.5 4.5 3 3 50 5 NO NO COL22A1:p.G1530A 124 22 17.7 8:139606286 151 12 7.9 8:139606286 242 25 10.3 8:139606286 146 10 6.8 8:139606286 202 26 12.9 8:139606286 221 24 10.9 8:139606286 106 5 4.7 8:139606286 167 22 13.2 8:139606286 98 1 1 8:139606286 282 11 3.9 PD14705b 17 65908730 G T BPTF CCDS11673.1 r.4931g>u c.4730G>T p.G1577V Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 89 pS 4.5 4.5 3 3 50 5 NO NO BPTF:p.G1577V 174 9 5.2 17:65908730 148 0 0 17:65908730 95 0 0 17:65908730 121 0 0 17:65908730 102 0 0 17:65908730 77 0 0 17:65908730 144 0 0 17:65908730 147 0 0 17:65908730 163 0 0 17:65908730 154 0 0 PD14705b 4 153258964 A G FBXW7 CCDS3777.1 r.1000u>c c.851T>C p.L284P Sub missense 2 UNKNOWN_OTHER UNKNOWN 89 pS 4.5 4.5 3 3 50 5 NO NO FBXW7:p.L284P 92 9 9.8 4:153258964 59 0 0 4:153258964 14 0 0 4:153258964 76 0 0 4:153258964 46 0 0 4:153258964 42 0 0 4:153258964 101 0 0 4:153258964 22 0 0 4:153258964 120 0 0 4:153258964 46 0 0 PD14705b 6 117730805 G C ROS1 CCDS5116.1 r.428c>g c.229C>G p.R77G Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 89 pS 4.5 4.5 3 3 50 5 NO NO ROS1:p.R77G 62 32 51.6 6:117730805 81 25 30.9 6:117730805 126 26 20.6 6:117730805 63 9 14.3 6:117730805 93 19 20.4 6:117730805 60 15 25 6:117730805 66 7 10.6 6:117730805 110 23 20.9 6:117730805 98 3 3.1 6:117730805 132 6 4.5 PD14705b 11 118374275 A G MLL CCDS31686.1 r.7682a>g c.7659A>G p.T2553T Sub silent 1 SILENT SILENT 89 pS 4.5 4.5 3 3 50 5 NO NO MLL:p.T2553T 212 74 34.9 11:118374275 213 81 38 11:118374275 223 80 35.9 11:118374275 182 46 25.3 11:118374275 207 56 27.1 11:118374275 143 47 32.9 11:118374275 174 35 20.1 11:118374275 342 125 36.5 11:118374275 243 16 6.6 11:118374275 245 36 14.7 PD14705b 17 7578406 C T TP53 CCDS11118.1 r.714g>a c.524G>A p.R175H Sub missense 1 CANONICAL_ONCOGENIC_BCA_GENE ONCOGENIC 89 pS 4.5 4.5 3 3 50 5 NO NO TP53:p.R175H 211 112 53.1 17:7578406 204 86 42.2 17:7578406 339 184 54.3 17:7578406 261 96 36.8 17:7578406 342 156 45.6 17:7578406 353 179 50.7 17:7578406 179 74 41.3 17:7578406 255 126 49.4 17:7578406 169 18 10.7 17:7578406 638 133 20.8