Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14748a TUM_PILEUP_MUTS_PD14748a Pileup_MtAlpct_PD14748a ID.2 DEPTH_PD14748c TUM_PILEUP_MUTS_PD14748c Pileup_MtAlpct_PD14748c ID.3 DEPTH_PD14748d TUM_PILEUP_MUTS_PD14748d Pileup_MtAlpct_PD14748d ID.4 DEPTH_PD14748e TUM_PILEUP_MUTS_PD14748e Pileup_MtAlpct_PD14748e ID.5 DEPTH_PD14748f TUM_PILEUP_MUTS_PD14748f Pileup_MtAlpct_PD14748f ID.6 DEPTH_PD14748g TUM_PILEUP_MUTS_PD14748g Pileup_MtAlpct_PD14748g ID.7 DEPTH_PD14748h TUM_PILEUP_MUTS_PD14748h Pileup_MtAlpct_PD14748h PD14748b 3 47165230 C A SETD2 CCDS2749.2 r.939g>u c.896G>T p.S299I Sub missense 1 UNKNOWN_BCA UNKNOWN 49 RD 5 3.8 1 3 5 1 YES YES SETD2:p.S299I 4 0 0 3:47165230 46 3 6.5 3:47165230 80 0 0 3:47165230 313 0 0 3:47165230 165 1 0.6 3:47165230 41 0 0 3:47165230 55 0 0 PD14748b 3 178936082 G A PIK3CA CCDS43171.1 r.1781g>a c.1624G>A p.E542K Sub missense 1 CANONICAL_ONCOGENIC_BCA_GENE ONCOGENIC 49 RD 5 3.8 1 3 5 1 YES YES PIK3CA:p.E542K 1 0 0 3:178936082 26 5 19.2 3:178936082 78 6 7.7 3:178936082 315 18 5.7 3:178936082 181 11 6.1 3:178936082 33 2 6.1 3:178936082 57 2 3.5