Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14749a TUM_PILEUP_MUTS_PD14749a Pileup_MtAlpct_PD14749a ID.2 DEPTH_PD14749c TUM_PILEUP_MUTS_PD14749c Pileup_MtAlpct_PD14749c PD14749b 1 27099021 C G ARID1A CCDS285.1 r.3808c>g c.3437C>G p.T1146S Sub missense 1 UNKNOWN_BCA UNKNOWN 43 RD 6 6 1 3 15 15 YES YES ARID1A:p.T1146S 199 83 41.7 1:27099021 100 48 48 PD14749b 17 56435274 C T RNF43 CCDS11607.1 r.2351g>a c.1863G>A p.E621E Sub silent 3 SILENT SILENT 43 RD 6 6 1 3 15 15 YES YES RNF43:p.E621E 317 48 15.1 17:56435274 174 33 19 PD14749b 13 32893435 G T BRCA2 CCDS9344.1 r.522g>u c.289G>T p.E97* Sub nonsense 1 DAMAGING_IN_BCA_GENE ONCOGENIC 43 RD 6 6 1 3 15 15 YES YES BRCA2:p.E97* 64 20 31.2 13:32893435 41 14 34.1