Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14751a TUM_PILEUP_MUTS_PD14751a Pileup_MtAlpct_PD14751a ID.2 DEPTH_PD14751c TUM_PILEUP_MUTS_PD14751c Pileup_MtAlpct_PD14751c PD14751b 13 32945129 C T BRCA2 CCDS9344.1 r.8757c>u c.8524C>T p.R2842C Sub missense 1 ONCOGENIC_BCA_GENE ONCOGENIC 49 RD 3 0.8 3 1 45 0 YES YES BRCA2:p.R2842C 147 115 78.2 13:32945129 181 129 71.3 PD14751b 3 142185192 C A ATR CCDS3124.1 r.6993g>u c.6871G>T p.A2291S Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 49 RD 3 0.8 3 1 45 0 YES YES ATR:p.A2291S 85 51 60 3:142185192 80 49 61.3 PD14751b 1 162731074 C T DDR2 CCDS1241.1 r.1367c>u c.929C>T p.A310V Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 49 RD 3 0.8 3 1 45 0 YES YES DDR2:p.A310V 263 0 0 1:162731074 381 37 9.7 PD14751b 17 7578406 C T TP53 CCDS11118.1 r.714g>a c.524G>A p.R175H Sub missense 1 CANONICAL_ONCOGENIC_BCA_GENE ONCOGENIC 49 RD 3 0.8 3 1 45 0 YES YES TP53:p.R175H 87 52 59.8 17:7578406 128 87 68