Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14754a TUM_PILEUP_MUTS_PD14754a Pileup_MtAlpct_PD14754a ID.2 DEPTH_PD14754c TUM_PILEUP_MUTS_PD14754c Pileup_MtAlpct_PD14754c PD14754b 5 180039582 C A FLT4 CCDS4457.1 r.3540g>u c.3461G>T p.G1154V Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 58 RD 2.4 0.5 3 3 60 1 YES YES FLT4:p.G1154V 202 97 48 5:180039582 154 79 51.3 PD14754b 22 38379483 G A SOX10 CCDS13964.1 r.592c>u c.309C>T p.H103H Sub silent 3 SILENT SILENT 58 RD 2.4 0.5 3 3 60 1 YES YES SOX10:p.H103H 194 75 38.7 22:38379483 180 58 32.2 PD14754b 14 81609290 T G TSHR CCDS9872.1 r.1044u>g c.888T>G p.L296L Sub silent 3 SILENT SILENT 58 RD 2.4 0.5 3 3 60 1 YES YES TSHR:p.L296L 135 54 40 14:81609290 90 35 38.9 PD14754b 13 28623606 T C FLT3 CCDS31953.1 r.1033a>g c.951A>G p.V317V Sub silent 2 UNKNOWN_OTHER SILENT 58 RD 2.4 0.5 3 3 60 1 YES YES FLT3:p.V317V 59 8 13.6 13:28623606 101 17 16.8 PD14754b 19 1223083 C G STK11 CCDS45896.1 r.2135c>g c.1020C>G p.Y340* Sub nonsense 1 DAMAGING_IN_BCA_GENE ONCOGENIC 58 RD 2.4 0.5 3 3 60 1 YES YES STK11:p.Y340* 238 185 77.7 19:1223083 185 126 68.1