Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14756a TUM_PILEUP_MUTS_PD14756a Pileup_MtAlpct_PD14756a ID.2 DEPTH_PD14756c TUM_PILEUP_MUTS_PD14756c Pileup_MtAlpct_PD14756c PD14756b 5 176518800 G A FGFR4 CCDS4410.1 r.963g>a c.718G>A p.D240N Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 47 pCR 3.2 0 3 1 60 0 YES YES FGFR4:p.D240N 118 20 16.9 5:176518800 109 0 0 PD14756b 20 57428453 C T GNAS CCDS46622.1 r.136c>u c.133C>T p.P45S Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 47 pCR 3.2 0 3 1 60 0 YES YES GNAS:p.P45S 617 130 21.1 20:57428453 450 125 27.8 PD14756b 3 77617532 C T ROBO2 CCDS43109.1 r.2818c>u c.1918C>T p.R640C Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 47 pCR 3.2 0 3 1 60 0 YES YES ROBO2:p.R640C 242 77 31.8 3:77617532 166 63 38 PD14756b 17 7578460 A C TP53 CCDS11118.1 r.660u>g c.470T>G p.V157G Sub missense 1 ONCOGENIC_BCA_GENE ONCOGENIC 47 pCR 3.2 0 3 1 60 0 YES YES TP53:p.V157G 233 113 48.5 17:7578460 363 216 59.5