Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14757a TUM_PILEUP_MUTS_PD14757a Pileup_MtAlpct_PD14757a ID.2 DEPTH_PD14757c TUM_PILEUP_MUTS_PD14757c Pileup_MtAlpct_PD14757c ID.3 DEPTH_PD14757d TUM_PILEUP_MUTS_PD14757d Pileup_MtAlpct_PD14757d ID.4 DEPTH_PD14757e TUM_PILEUP_MUTS_PD14757e Pileup_MtAlpct_PD14757e ID.5 DEPTH_PD14757f TUM_PILEUP_MUTS_PD14757f Pileup_MtAlpct_PD14757f ID.6 DEPTH_PD14757g TUM_PILEUP_MUTS_PD14757g Pileup_MtAlpct_PD14757g ID.7 DEPTH_PD14757h TUM_PILEUP_MUTS_PD14757h Pileup_MtAlpct_PD14757h ID.8 DEPTH_PD14757i TUM_PILEUP_MUTS_PD14757i Pileup_MtAlpct_PD14757i PD14757b 2 48027799 C T MSH6 CCDS1836.1 r.2829c>u c.2677C>T p.L893L Sub silent 3 SILENT SILENT 48 RD 4 5.4 1 3 5 1 YES YES MSH6:p.L893L 143 0 0 2:48027799 115 0 0 2:48027799 234 27 11.5 2:48027799 136 16 11.8 2:48027799 178 3 1.7 2:48027799 103 4 3.9 2:48027799 53 5 9.4 2:48027799 101 9 8.9 PD14757b X 70346843 G T MED12 CCDS43970.1 r.2742g>u c.2710G>T p.E904* Sub nonsense 2 DAMAGING_OTHER_GENE ONCOGENIC 48 RD 4 5.4 1 3 5 1 YES YES MED12:p.E904* 90 0 0 X:70346843 66 5 7.6 X:70346843 168 0 0 X:70346843 71 0 0 X:70346843 160 0 0 X:70346843 96 0 0 X:70346843 42 0 0 X:70346843 60 0 0