Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14758a TUM_PILEUP_MUTS_PD14758a Pileup_MtAlpct_PD14758a ID.2 DEPTH_PD14758c TUM_PILEUP_MUTS_PD14758c Pileup_MtAlpct_PD14758c ID.3 DEPTH_PD14758d TUM_PILEUP_MUTS_PD14758d Pileup_MtAlpct_PD14758d ID.4 DEPTH_PD14758e TUM_PILEUP_MUTS_PD14758e Pileup_MtAlpct_PD14758e ID.5 DEPTH_PD14758f TUM_PILEUP_MUTS_PD14758f Pileup_MtAlpct_PD14758f ID.6 DEPTH_PD14758g TUM_PILEUP_MUTS_PD14758g Pileup_MtAlpct_PD14758g ID.7 DEPTH_PD14758h TUM_PILEUP_MUTS_PD14758h Pileup_MtAlpct_PD14758h ID.8 DEPTH_PD14758i TUM_PILEUP_MUTS_PD14758i Pileup_MtAlpct_PD14758i ID.9 DEPTH_PD14758j TUM_PILEUP_MUTS_PD14758j Pileup_MtAlpct_PD14758j PD14758b 10 89692893 C A PTEN ENST00000371953 r.1734c>a c.377C>A p.A126D Sub missense 1 ONCOGENIC_BCA_GENE ONCOGENIC 34 RD 5.5 6 2 3 30 12 YES YES PTEN:p.A126D 101 60 59.4 10:89692893 132 86 65.2 10:89692893 153 57 37.3 10:89692893 71 21 29.6 10:89692893 88 24 27.3 10:89692893 290 70 24.1 10:89692893 200 45 22.5 10:89692893 207 57 27.5 10:89692893 249 68 27.3 PD14758b 19 10602489 G A KEAP1 CCDS12239.1 r.1274c>u c.1089C>T p.S363S Sub silent 2 SILENT SILENT 34 RD 5.5 6 2 3 30 12 YES YES KEAP1:p.S363S 267 40 15 19:10602489 80 0 0 19:10602489 139 0 0 19:10602489 244 0 0 19:10602489 185 0 0 19:10602489 365 0 0 19:10602489 137 0 0 19:10602489 140 0 0 19:10602489 101 0 0