Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14767a TUM_PILEUP_MUTS_PD14767a Pileup_MtAlpct_PD14767a ID.2 DEPTH_PD14767c TUM_PILEUP_MUTS_PD14767c Pileup_MtAlpct_PD14767c ID.3 DEPTH_PD14767d TUM_PILEUP_MUTS_PD14767d Pileup_MtAlpct_PD14767d ID.4 DEPTH_PD14767e TUM_PILEUP_MUTS_PD14767e Pileup_MtAlpct_PD14767e ID.5 DEPTH_PD14767f TUM_PILEUP_MUTS_PD14767f Pileup_MtAlpct_PD14767f ID.6 DEPTH_PD14767g TUM_PILEUP_MUTS_PD14767g Pileup_MtAlpct_PD14767g ID.7 DEPTH_PD14767h TUM_PILEUP_MUTS_PD14767h Pileup_MtAlpct_PD14767h PD14767b 10 89653815 C T PTEN ENST00000371953 r.1470c>u c.113C>T p.P38L Sub missense 1 UNKNOWN_BCA UNKNOWN 46 RD 3.2 3 3 3 25 0 YES YES PTEN:p.P38L 74 7 9.5 10:89653815 62 2 3.2 10:89653815 79 2 2.5 10:89653815 240 3 1.2 10:89653815 201 15 7.5 10:89653815 138 7 5.1 10:89653815 275 25 9.1 PD14767b 6 117665418 C T ROS1 CCDS5116.1 r.4528g>a c.4329G>A p.A1443A Sub silent 3 SILENT SILENT 46 RD 3.2 3 3 3 25 0 YES YES ROS1:p.A1443A 94 12 12.8 6:117665418 102 10 9.8 6:117665418 83 1 1.2 6:117665418 185 0 0 6:117665418 116 13 11.2 6:117665418 93 0 0 6:117665418 130 10 7.7 PD14767b 3 178952085 A G PIK3CA CCDS43171.1 r.3297a>g c.3140A>G p.H1047R Sub missense 1 CANONICAL_ONCOGENIC_BCA_GENE ONCOGENIC 46 RD 3.2 3 3 3 25 0 YES YES PIK3CA:p.H1047R 100 44 44 3:178952085 100 30 30 3:178952085 103 19 18.4 3:178952085 232 13 5.6 3:178952085 154 63 40.9 3:178952085 122 13 10.7 3:178952085 127 54 42.5 PD14767b 17 7578406 C T TP53 CCDS11118.1 r.714g>a c.524G>A p.R175H Sub missense 1 CANONICAL_ONCOGENIC_BCA_GENE ONCOGENIC 46 RD 3.2 3 3 3 25 0 YES YES TP53:p.R175H 192 58 30.2 17:7578406 264 72 27.3 17:7578406 363 29 8 17:7578406 113 2 1.8 17:7578406 204 78 38.2 17:7578406 288 25 8.7 17:7578406 95 36 37.9