Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14769a TUM_PILEUP_MUTS_PD14769a Pileup_MtAlpct_PD14769a ID.2 DEPTH_PD14769c TUM_PILEUP_MUTS_PD14769c Pileup_MtAlpct_PD14769c PD14769b 18 48591901 A G SMAD4 CCDS11950.1 r.1602a>g c.1064A>G p.D355G Sub missense 1 POSSIBLE_ONCOGENIC POSSIBLE_ONCOGENIC 53 pCR 6 0 2 2 25 0 YES YES SMAD4:p.D355G 127 10 7.9 18:48591901 115 6 5.2 PD14769b 12 96640988 G T ELK3 CCDS9060.1 r.757g>u c.478G>T p.A160S Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 53 pCR 6 0 2 2 25 0 YES YES ELK3:p.A160S 142 29 20.4 12:96640988 112 33 29.5 PD14769b 17 38450738 C A CDC6 CCDS11365.1 r.1537c>a c.1066C>A p.Q356K Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 53 pCR 6 0 2 2 25 0 YES YES CDC6:p.Q356K 1199 35 2.9 17:38450738 1536 48 3.1 PD14769b 2 25472561 G A DNMT3A CCDS1718.2 r.151c>u c.37C>T p.R13C Sub missense 2 UNKNOWN_OTHER UNKNOWN 53 pCR 6 0 2 2 25 0 YES YES DNMT3A:p.R13C 212 39 18.4 2:25472561 222 45 20.3