Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14770a TUM_PILEUP_MUTS_PD14770a Pileup_MtAlpct_PD14770a ID.2 DEPTH_PD14770c TUM_PILEUP_MUTS_PD14770c Pileup_MtAlpct_PD14770c ID.3 DEPTH_PD14770d TUM_PILEUP_MUTS_PD14770d Pileup_MtAlpct_PD14770d PD14770b 6 138199702 G T TNFAIP3 CCDS5187.1 r.1186g>u c.1120G>T p.E374* Sub nonsense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 61 RD 2.8 1.4 3 2 80 0 YES YES TNFAIP3:p.E374* 305 4 1.3 6:138199702 446 25 5.6 6:138199702 224 0 0 PD14770b 1 154942698 G C SHC1 CCDS44233.1 r.526c>g c.305C>G p.S102* Sub nonsense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 61 RD 2.8 1.4 3 2 80 0 YES YES SHC1:p.S102* 434 3 0.7 1:154942698 725 76 10.5 1:154942698 167 0 0 PD14770b 3 178952085 A G PIK3CA CCDS43171.1 r.3297a>g c.3140A>G p.H1047R Sub missense 1 CANONICAL_ONCOGENIC_BCA_GENE ONCOGENIC 61 RD 2.8 1.4 3 2 80 0 YES YES PIK3CA:p.H1047R 82 15 18.3 3:178952085 125 25 20 3:178952085 148 19 12.8