Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14774a TUM_PILEUP_MUTS_PD14774a Pileup_MtAlpct_PD14774a ID.2 DEPTH_PD14774c TUM_PILEUP_MUTS_PD14774c Pileup_MtAlpct_PD14774c ID.3 DEPTH_PD14774d TUM_PILEUP_MUTS_PD14774d Pileup_MtAlpct_PD14774d PD14774b 7 140624476 C G BRAF CCDS5863.1 r.89g>c c.28G>C p.G10R Sub missense 2 UNKNOWN_OTHER UNKNOWN 51 pCR 2.7 0 3 1 90 1 YES YES BRAF:p.G10R 215 0 0 7:140624476 176 0 0 7:140624476 127 21 16.5 PD14774b 6 157511229 G A ARID1B CCDS5251.1 r.3845g>a c.3693G>A p.P1231P Sub silent 2 SILENT SILENT 51 pCR 2.7 0 3 1 90 1 YES YES ARID1B:p.P1231P 520 0 0 6:157511229 548 9 1.6 6:157511229 402 122 30.3 PD14774b 8 69136848 C A PREX2 CCDS6201.1 r.5039c>a c.4762C>A p.Q1588K Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 51 pCR 2.7 0 3 1 90 1 YES YES PREX2:p.Q1588K 385 86 22.3 8:69136848 317 56 17.7 8:69136848 363 52 14.3 PD14774b 14 95572535 G T DICER1 CCDS9931.1 r.3068c>a c.2830C>A p.R944R Sub silent 3 SILENT SILENT 51 pCR 2.7 0 3 1 90 1 YES YES DICER1:p.R944R 24 4 16.7 14:95572535 23 0 0 14:95572535 120 0 0 PD14774b 16 2120566 G T TSC2 CCDS10458.1 r.2456g>u c.1826G>T p.S609I Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 51 pCR 2.7 0 3 1 90 1 YES YES TSC2:p.S609I 1046 345 33 16:2120566 909 268 29.5 16:2120566 368 137 37.2 PD14774b 6 44218306 T C HSP90AB1 CCDS4909.1 r.1141u>c c.927T>C p.T309T Sub silent 2 SILENT SILENT 51 pCR 2.7 0 3 1 90 1 YES YES HSP90AB1:p.T309T 86 39 45.3 6:44218306 104 13 12.5 6:44218306 137 0 0