Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD14776a TUM_PILEUP_MUTS_PD14776a Pileup_MtAlpct_PD14776a ID.2 DEPTH_PD14776c TUM_PILEUP_MUTS_PD14776c Pileup_MtAlpct_PD14776c ID.3 DEPTH_PD14776d TUM_PILEUP_MUTS_PD14776d Pileup_MtAlpct_PD14776d PD14776b 9 21971036 C T CDKN2A CCDS6510.1 r.593g>a c.322G>A p.D108N Sub missense 1 ONCOGENIC_BCA_GENE ONCOGENIC 50 RD 2.4 2.1 3 1 70 0 YES YES CDKN2A:p.D108N 282 88 31.2 9:21971036 414 73 17.6 9:21971036 503 0 0 PD14776b 17 7578393 A T TP53 CCDS11118.1 r.727u>a c.537T>A p.H179Q Sub missense 1 ONCOGENIC_BCA_GENE ONCOGENIC 50 RD 2.4 2.1 3 1 70 0 YES YES TP53:p.H179Q 232 71 30.6 17:7578393 340 61 17.9 17:7578393 85 0 0 PD14776b X 63410260 C T FAM123B CCDS14377.2 r.3180g>a c.2907G>A p.G969G Sub silent 3 SILENT SILENT 50 RD 2.4 2.1 3 1 70 0 YES YES FAM123B:p.G969G 114 0 0 X:63410260 133 0 0 X:63410260 79 10 12.7 PD14776b 17 60142510 G C MED13 CCDS42366.1 r.134c>g c.57C>G p.L19L Sub silent 3 SILENT SILENT 50 RD 2.4 2.1 3 1 70 0 YES YES MED13:p.L19L 295 10 3.4 17:60142510 377 15 4 17:60142510 513 0 0 PD14776b 20 39794915 C T PLCG1 CCDS13313.1 r.2286c>u c.1881C>T p.L627L Sub silent 3 SILENT SILENT 50 RD 2.4 2.1 3 1 70 0 YES YES PLCG1:p.L627L 238 37 15.5 20:39794915 333 27 8.1 20:39794915 185 0 0 PD14776b 20 57428833 G A GNAS CCDS46622.1 r.516g>a c.513G>A p.Q171Q Sub silent 3 SILENT SILENT 50 RD 2.4 2.1 3 1 70 0 YES YES GNAS:p.Q171Q 152 21 13.8 20:57428833 180 12 6.7 20:57428833 150 0 0 PD14776b X 39935756 G A BCOR CCDS48093.1 r.345c>u c.116C>T p.S39L Sub missense 2 UNKNOWN_OTHER UNKNOWN 50 RD 2.4 2.1 3 1 70 0 YES YES BCOR:p.S39L 172 17 9.9 X:39935756 126 8 6.3 X:39935756 156 0 0 PD14776b 3 87325590 G A POU1F1 CCDS46873.1 r.108c>u c.23C>T p.S8L Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 50 RD 2.4 2.1 3 1 70 0 YES YES POU1F1:p.S8L 109 19 17.4 3:87325590 118 7 5.9 3:87325590 243 0 0 PD14776b 16 2115600 G A TSC2 CCDS10458.1 r.2310g>a c.1680G>A p.V560V Sub silent 3 SILENT SILENT 50 RD 2.4 2.1 3 1 70 0 YES YES TSC2:p.V560V 132 15 11.4 16:2115600 151 7 4.6 16:2115600 33 1 3