Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD9694e TUM_PILEUP_MUTS_PD9694e Pileup_MtAlpct_PD9694e ID.2 DEPTH_PD9694f TUM_PILEUP_MUTS_PD9694f Pileup_MtAlpct_PD9694f ID.3 DEPTH_PD9694g TUM_PILEUP_MUTS_PD9694g Pileup_MtAlpct_PD9694g ID.4 DEPTH_PD9694h TUM_PILEUP_MUTS_PD9694h Pileup_MtAlpct_PD9694h ID.5 DEPTH_PD9694i TUM_PILEUP_MUTS_PD9694i Pileup_MtAlpct_PD9694i ID.6 DEPTH_PD9694j TUM_PILEUP_MUTS_PD9694j Pileup_MtAlpct_PD9694j ID.7 DEPTH_PD9694k TUM_PILEUP_MUTS_PD9694k Pileup_MtAlpct_PD9694k ID.8 DEPTH_PD9694l TUM_PILEUP_MUTS_PD9694l Pileup_MtAlpct_PD9694l ID.9 DEPTH_PD9694m TUM_PILEUP_MUTS_PD9694m Pileup_MtAlpct_PD9694m ID.10 DEPTH_PD9694n TUM_PILEUP_MUTS_PD9694n Pileup_MtAlpct_PD9694n ID.11 DEPTH_PD9694o TUM_PILEUP_MUTS_PD9694o Pileup_MtAlpct_PD9694o ID.12 DEPTH_PD9694p TUM_PILEUP_MUTS_PD9694p Pileup_MtAlpct_PD9694p ID.13 DEPTH_PD9694q TUM_PILEUP_MUTS_PD9694q Pileup_MtAlpct_PD9694q ID.14 DEPTH_PD9694r TUM_PILEUP_MUTS_PD9694r Pileup_MtAlpct_PD9694r ID.15 DEPTH_PD9694s TUM_PILEUP_MUTS_PD9694s Pileup_MtAlpct_PD9694s ID.16 DEPTH_PD9694t TUM_PILEUP_MUTS_PD9694t Pileup_MtAlpct_PD9694t ID.17 DEPTH_PD9694u TUM_PILEUP_MUTS_PD9694u Pileup_MtAlpct_PD9694u PD9694b 10 89692911 G A PTEN ENST00000371953 r.1752g>a c.395G>A p.G132D Sub missense 1 ONCOGENIC_BCA_GENE ONCOGENIC 37 pS 2.6 2.6 2 3 NA 1 YES YES PTEN:p.G132D 307 35 11.4 10:89692911 328 78 23.8 10:89692911 259 4 1.5 10:89692911 187 0 0 10:89692911 287 0 0 10:89692911 61 8 13.1 10:89692911 180 13 7.2 10:89692911 83 0 0 10:89692911 491 0 0 10:89692911 292 1 0.3 10:89692911 203 0 0 10:89692911 217 0 0 10:89692911 245 0 0 10:89692911 187 0 0 10:89692911 225 0 0 10:89692911 214 31 14.5 10:89692911 217 37 17.1 PD9694b 3 47108598 C T SETD2 CCDS2749.2 r.6114g>a c.6071G>A p.R2024Q Sub missense 1 UNKNOWN_BCA UNKNOWN 37 pS 2.6 2.6 2 3 NA 1 YES YES SETD2:p.R2024Q 137 1 0.7 3:47108598 189 0 0 3:47108598 149 0 0 3:47108598 53 0 0 3:47108598 161 10 6.2 3:47108598 26 0 0 3:47108598 21 0 0 3:47108598 16 0 0 3:47108598 260 0 0 3:47108598 155 1 0.6 3:47108598 99 0 0 3:47108598 98 0 0 3:47108598 110 0 0 3:47108598 146 0 0 3:47108598 129 0 0 3:47108598 145 0 0 3:47108598 114 0 0 PD9694b 16 3820624 G A CREBBP CCDS10509.1 r.3632c>u c.2827C>T p.Q943* Sub nonsense 2 DAMAGING_BCA_GENE ONCOGENIC 37 pS 2.6 2.6 2 3 NA 1 YES YES CREBBP:p.Q943* 129 27 20.9 16:3820624 161 42 26.1 16:3820624 119 14 11.8 16:3820624 160 26 16.2 16:3820624 115 19 16.5 16:3820624 276 41 14.9 16:3820624 203 35 17.2 16:3820624 342 85 24.9 16:3820624 170 16 9.4 16:3820624 137 32 23.4 16:3820624 82 17 20.7 16:3820624 135 29 21.5 16:3820624 140 21 15 16:3820624 141 33 23.4 16:3820624 147 28 19 16:3820624 96 16 16.7 16:3820624 124 23 18.5 PD9694b 2 198266834 T C SF3B1 CCDS33356.1 r.2190a>g c.2098A>G p.K700E Sub missense 1 CANONICAL_ONCOGENIC_BCA_GENE ONCOGENIC 37 pS 2.6 2.6 2 3 NA 1 YES YES SF3B1:p.K700E 194 53 27.3 2:198266834 236 46 19.5 2:198266834 191 39 20.4 2:198266834 228 48 21.1 2:198266834 195 48 24.6 2:198266834 225 58 25.8 2:198266834 226 63 27.9 2:198266834 360 109 30.3 2:198266834 294 30 10.2 2:198266834 203 56 27.6 2:198266834 142 36 25.4 2:198266834 168 50 29.8 2:198266834 210 48 22.9 2:198266834 206 64 31.1 2:198266834 198 47 23.7 2:198266834 181 41 22.7 2:198266834 252 65 25.8 PD9694b 10 89692904 C T PTEN ENST00000371953 r.1745c>u c.388C>T p.R130* Sub nonsense 1 DAMAGING_IN_BCA_GENE ONCOGENIC 37 pS 2.6 2.6 2 3 NA 1 YES YES PTEN:p.R130* 322 0 0 10:89692904 341 0 0 10:89692904 267 0 0 10:89692904 191 0 0 10:89692904 293 27 9.2 10:89692904 62 0 0 10:89692904 175 1 0.6 10:89692904 84 0 0 10:89692904 525 0 0 10:89692904 299 1 0.3 10:89692904 206 0 0 10:89692904 224 0 0 10:89692904 257 3 1.2 10:89692904 194 1 0.5 10:89692904 245 0 0 10:89692904 220 0 0 10:89692904 230 0 0