Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD9771a2 TUM_PILEUP_MUTS_PD9771a2 Pileup_MtAlpct_PD9771a2 ID.2 DEPTH_PD9771d TUM_PILEUP_MUTS_PD9771d Pileup_MtAlpct_PD9771d ID.3 DEPTH_PD9771e TUM_PILEUP_MUTS_PD9771e Pileup_MtAlpct_PD9771e ID.4 DEPTH_PD9771f TUM_PILEUP_MUTS_PD9771f Pileup_MtAlpct_PD9771f ID.5 DEPTH_PD9771g TUM_PILEUP_MUTS_PD9771g Pileup_MtAlpct_PD9771g ID.6 DEPTH_PD9771h TUM_PILEUP_MUTS_PD9771h Pileup_MtAlpct_PD9771h PD9771b 19 15302325 C T NOTCH3 CCDS12326.1 r.1022g>a c.946G>A p.D316N Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 52 RD 6 0.2 3 1 90 0 YES NO NOTCH3:p.D316N 126 41 32.5 19:15302325 160 21 13.1 19:15302325 87 0 0 19:15302325 39 0 0 19:15302325 25 0 0 19:15302325 35 0 0 PD9771b 4 55968128 G C KDR CCDS3497.1 r.2498c>g c.2202C>G p.L734L Sub silent 3 SILENT SILENT 52 RD 6 0.2 3 1 90 0 YES NO KDR:p.L734L 172 40 23.3 4:55968128 132 25 18.9 4:55968128 112 25 22.3 4:55968128 65 4 6.2 4:55968128 33 3 9.1 4:55968128 43 2 4.7 PD9771b 17 7579366 G T TP53 CCDS11118.1 r.511c>a c.321C>A p.Y107* Sub nonsense 1 DAMAGING_IN_BCA_GENE ONCOGENIC 52 RD 6 0.2 3 1 90 0 YES NO TP53:p.Y107* 42 34 81 17:7579366 41 6 14.6 17:7579366 27 18 66.7 17:7579366 18 15 83.3 17:7579366 8 6 75 17:7579366 9 1 11.1