Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD9772a3 TUM_PILEUP_MUTS_PD9772a3 Pileup_MtAlpct_PD9772a3 ID.2 DEPTH_PD9772c TUM_PILEUP_MUTS_PD9772c Pileup_MtAlpct_PD9772c ID.3 DEPTH_PD9772d TUM_PILEUP_MUTS_PD9772d Pileup_MtAlpct_PD9772d PD9772b 5 112175087 G C APC CCDS4107.1 r.4176g>c c.3796G>C p.D1266H Sub missense 1 UNKNOWN_BCA_GENE UNKNOWN 46 pCR 3.7 0 3 1 95 0 YES YES APC:p.D1266H 68 0 0 5:112175087 36 2 5.6 5:112175087 48 8 16.7 PD9772b 16 343528 C A AXIN1 CCDS10405.1 r.2518g>u c.2146G>T p.E716* Sub nonsense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 46 pCR 3.7 0 3 1 95 0 YES YES AXIN1:p.E716* 46 37 80.4 16:343528 24 16 66.7 16:343528 39 23 59 PD9772b 7 27148184 G A HOXA3 CCDS5404.1 r.882c>u c.682C>T p.L228L Sub silent 3 SILENT SILENT 46 pCR 3.7 0 3 1 95 0 YES YES HOXA3:p.L228L 110 64 58.2 7:27148184 93 38 40.9 7:27148184 108 36 33.3 PD9772b 3 10084343 T G FANCD2 CCDS2595.1 r.977u>g c.884T>G p.L295R Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 46 pCR 3.7 0 3 1 95 0 YES YES FANCD2:p.L295R 63 47 74.6 3:10084343 46 32 69.6 3:10084343 85 52 61.2 PD9772b 5 180057561 C T FLT4 CCDS4457.1 r.473g>a c.394G>A p.V132M Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 46 pCR 3.7 0 3 1 95 0 YES YES FLT4:p.V132M 51 0 0 5:180057561 15 4 26.7 5:180057561 25 1 4 PD9772b 11 108115649 G T ATM CCDS31669.1 r.1182g>u c.797G>T p.W266L Sub missense 2 UNKNOWN_OTHER UNKNOWN 46 pCR 3.7 0 3 1 95 0 YES YES ATM:p.W266L 60 38 63.3 11:108115649 26 8 30.8 11:108115649 51 25 49 PD9772b 17 7578263 G A TP53 CCDS11118.1 r.776c>u c.586C>T p.R196* Sub nonsense 1 DAMAGING_IN_BCA_GENE ONCOGENIC 46 pCR 3.7 0 3 1 95 0 YES YES TP53:p.R196* 250 210 84 17:7578263 146 103 70.5 17:7578263 182 110 60.4