Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD9773a2 TUM_PILEUP_MUTS_PD9773a2 Pileup_MtAlpct_PD9773a2 ID.2 DEPTH_PD9773c TUM_PILEUP_MUTS_PD9773c Pileup_MtAlpct_PD9773c ID.3 DEPTH_PD9773d TUM_PILEUP_MUTS_PD9773d Pileup_MtAlpct_PD9773d PD9773b 11 118344656 A T MLL CCDS31686.1 r.2805a>u c.2782A>T p.K928* Sub nonsense 1 UNKNOWN_EFFECT_BCA_GENE UNKNOWN 49 pCR 2.3 0 3 1 60 0 YES YES MLL:p.K928* 161 0 0 11:118344656 176 0 0 11:118344656 59 7 11.9 PD9773b 6 157099486 C T ARID1B CCDS5251.1 r.401c>u c.249C>T p.G83G Sub silent 2 SILENT SILENT 49 pCR 2.3 0 3 1 60 0 YES YES ARID1B:p.G83G 101 4 4 6:157099486 129 13 10.1 6:157099486 21 7 33.3 PD9773b 17 65908646 T C BPTF CCDS11673.1 r.4847u>c c.4646T>C p.I1549T Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 49 pCR 2.3 0 3 1 60 0 YES YES BPTF:p.I1549T 135 6 4.4 17:65908646 137 15 10.9 17:65908646 52 12 23.1 PD9773b 17 7577538 C T TP53 CCDS11118.1 r.933g>a c.743G>A p.R248Q Sub missense 1 CANONICAL_ONCOGENIC_BCA_GENE ONCOGENIC 49 pCR 2.3 0 3 1 60 0 YES YES TP53:p.R248Q 137 7 5.1 17:7577538 176 17 9.7 17:7577538 39 9 23.1