Normal Chrom Pos Ref Alt Gene Transcript RNA CDS Protein Type Effect CancerGene Description DRIVER_CATEGORY Age pCR_vs_RD PreTxTumorSizeClinOrRad Tumor_size_surgery(cm) Grade group Ki67_biopsy NumPosLn ANTHRACYCLINE TAXANE geneRef DEPTH_PD9849a TUM_PILEUP_MUTS_PD9849a Pileup_MtAlpct_PD9849a ID.2 DEPTH_PD9849c TUM_PILEUP_MUTS_PD9849c Pileup_MtAlpct_PD9849c ID.3 DEPTH_PD9849d TUM_PILEUP_MUTS_PD9849d Pileup_MtAlpct_PD9849d ID.4 DEPTH_PD9849e TUM_PILEUP_MUTS_PD9849e Pileup_MtAlpct_PD9849e ID.5 DEPTH_PD9849f TUM_PILEUP_MUTS_PD9849f Pileup_MtAlpct_PD9849f ID.6 DEPTH_PD9849g TUM_PILEUP_MUTS_PD9849g Pileup_MtAlpct_PD9849g ID.7 DEPTH_PD9849h TUM_PILEUP_MUTS_PD9849h Pileup_MtAlpct_PD9849h ID.8 DEPTH_PD9849i TUM_PILEUP_MUTS_PD9849i Pileup_MtAlpct_PD9849i PD9849b 17 7578478 G C TP53 CCDS11118.1 r.642c>g c.452C>G p.P151R Sub missense 1 ONCOGENIC_BCA_GENE ONCOGENIC 58 pS 3 3 2 3 20 3 YES YES TP53:p.P151R 222 88 39.6 17:7578478 117 33 28.2 17:7578478 311 134 43.1 17:7578478 231 128 55.4 17:7578478 140 36 25.7 17:7578478 118 47 39.8 17:7578478 334 119 35.6 17:7578478 346 185 53.5 PD9849b 13 110435574 C A IRS2 CCDS9510.1 r.3342g>u c.2827G>T p.A943S Sub missense 3 UNCERTAIN_CANCER_GENE_STATUS_IN_BCA UNKNOWN 58 pS 3 3 2 3 20 3 YES YES IRS2:p.A943S 218 30 13.8 13:110435574 46 9 19.6 13:110435574 180 35 19.4 13:110435574 118 33 28 13:110435574 69 6 8.7 13:110435574 58 16 27.6 13:110435574 172 29 16.9 13:110435574 167 48 28.7