Optical Map Analysis: Alignments

Description

Optical Mapping (OM) is a system that produces ordered restriction maps from individual molecules of genomic DNA. Each single-molecule restriction map is a direct measurement of the source genome, free from biases introduced by cloning, amplification, or hybridization. This track presents the alignment of consensus maps generated from optical map analysis. It is complemented by the 'Optical Map Analysis: Deletions' track displaying unaligned parts of the consensus.

Display Conventions and Configuration

OM produces restriction fragments which occur in a known order within contigs, derived from specific cell lines. Each track corresponds to an analysis of OM data from a single cell line. Each contig is presented as a horizontal line, with restriction cut-sites dividing fragments being displayed as vertical lines along that contig. Where there is a space between the placement of successive restriction fragments according to this analysis, this is represented as a thicker vertical bar spanning the gap between the fragments.

Methods

Optical Mapping analysis. See References section below for further details.

Credits

OM data and alignments generated by the Schwartz lab, University of Wisconsin and used by the Genome Reference Consortium to improve reference assemblies. Contact us via genomereference.org or by emailing grc-help@sanger.ac.uk.

References