57 of 158 pathway holes were filled (36.1%).
|
Hole-filler
|
Hole EC#
|
P(has-function)
|
All functions of hole-filler
|
Pathway(s) requiring this reaction
|
Date filled
|
|
gene:Pan_g20088
|
none
|
0.969
|
gene:Pan_g20088
|
sphingosine and sphingosine-1-phosphate metabolism
|
26-Feb-2015
|
|
gene:Pan_g20088
|
none
|
0.969
|
gene:Pan_g20088
|
sphingosine and sphingosine-1-phosphate metabolism
|
26-Feb-2015
|
|
gene:Pan_g10675
|
4.2.1.22
|
0.912
|
gene:Pan_g10675
|
cysteine biosynthesis/homocysteine degradation
|
26-Feb-2015
|
|
gene:Pan_g10675
|
4.2.1.22
|
0.912
|
gene:Pan_g10675
|
cysteine biosynthesis/homocysteine degradation
|
26-Feb-2015
|
|
gene:Pan_g22010
|
2.4.1.134
|
0.966
|
gene:Pan_g22010
|
glycoaminoglycan-protein linkage region biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g22010
|
2.4.1.134
|
0.966
|
gene:Pan_g22010
|
glycoaminoglycan-protein linkage region biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g22124
|
3.1.6.4
|
0.941
|
gene:Pan_g22124
|
chondroitin sulfate degradation (metazoa)
|
26-Feb-2015
|
|
gene:Pan_g22124
|
3.1.6.4
|
0.941
|
gene:Pan_g22124
|
chondroitin sulfate degradation (metazoa)
|
26-Feb-2015
|
|
gene:Pan_g9768
|
1.1.1.94
|
0.946
|
gene:Pan_g9768
|
CDP-diacylglycerol biosynthesis I
|
26-Feb-2015
|
|
gene:Pan_g7628
|
1.14.19.3
|
0.937
|
gene:Pan_g7628
|
gamma-linolenate biosynthesis II (animals)
|
26-Feb-2015
|
|
gene:Pan_g7628
|
1.14.19.3
|
0.937
|
gene:Pan_g7628
|
gamma-linolenate biosynthesis II (animals)
|
26-Feb-2015
|
|
gene:Pan_g10177
|
1.5.1.8
|
0.997
|
gene:Pan_g10177
|
lysine degradation II
|
26-Feb-2015
|
|
gene:Pan_g10177
|
1.5.1.9
|
0.997
|
gene:Pan_g10177
|
lysine degradation II
|
26-Feb-2015
|
|
gene:Pan_g10177
|
1.5.1.8
|
0.997
|
gene:Pan_g10177
|
lysine degradation II
|
26-Feb-2015
|
|
gene:Pan_g10177
|
1.5.1.9
|
0.997
|
gene:Pan_g10177
|
lysine degradation II
|
26-Feb-2015
|
|
gene:Pan_g9139
|
1.1.1.300
|
0.978
|
gene:Pan_g9139
|
retinol biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g9139
|
1.1.1.300
|
0.978
|
gene:Pan_g9139
|
retinol biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g3940
|
1.5.99.8
|
0.993
|
gene:Pan_g3940
|
L-Ndelta-acetylornithine biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g3940
|
1.5.99.8
|
0.993
|
gene:Pan_g3940
|
L-Ndelta-acetylornithine biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g3942
|
2.3.1.29
|
0.989
|
gene:Pan_g3942
|
threonine degradation II
|
26-Feb-2015
|
|
gene:Pan_g3942
|
2.3.1.29
|
0.989
|
gene:Pan_g3942
|
threonine degradation II
|
26-Feb-2015
|
|
gene:Pan_g19571
|
2.7.7.80
|
0.980
|
gene:Pan_g19571
|
molybdenum cofactor biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g19571
|
2.8.1.11
|
0.966
|
gene:Pan_g19571
|
molybdenum cofactor biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g19571
|
2.7.7.80
|
0.980
|
gene:Pan_g19571
|
molybdenum cofactor biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g19571
|
2.8.1.11
|
0.966
|
gene:Pan_g19571
|
molybdenum cofactor biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g12989
|
none
|
0.903
|
gene:Pan_g12989
|
retinol biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g12989
|
none
|
0.903
|
gene:Pan_g12989
|
retinol biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g11693
|
2.7.7.23
|
0.987
|
gene:Pan_g11693
|
UDP-N-acetyl-D-glucosamine biosynthesis II
|
26-Feb-2015
|
|
gene:Pan_g11693
|
2.7.7.23
|
0.987
|
gene:Pan_g11693
|
UDP-N-acetyl-D-glucosamine biosynthesis II
|
26-Feb-2015
|
|
gene:Pan_g9626
|
2.2.1.6
|
0.970
|
gene:Pan_g9626
|
isoleucine biosynthesis I (from threonine)
|
26-Feb-2015
|
|
gene:Pan_g9626
|
2.2.1.6
|
0.970
|
gene:Pan_g9626
|
isoleucine biosynthesis I (from threonine)
|
26-Feb-2015
|
|
gene:Pan_g16959
|
3.2.1.33
|
0.997
|
gene:Pan_g16959
|
glycogen degradation II
|
26-Feb-2015
|
|
gene:Pan_g16959
|
2.4.1.25
|
0.997
|
gene:Pan_g16959
|
glycogen degradation II
|
26-Feb-2015
|
|
gene:Pan_g16959
|
3.2.1.33
|
0.997
|
gene:Pan_g16959
|
glycogen degradation II
|
26-Feb-2015
|
|
gene:Pan_g16959
|
2.4.1.25
|
0.997
|
gene:Pan_g16959
|
glycogen degradation II
|
26-Feb-2015
|
|
gene:Pan_g4800
|
2.7.8.11
|
0.965
|
gene:Pan_g4800
|
D-myo-inositol (1,4,5)-trisphosphate biosynthesis,
3-phosphoinositide biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g6554
|
none
|
0.994
|
gene:Pan_g6554
|
ceramide degradation
|
26-Feb-2015
|
|
gene:Pan_g6554
|
none
|
0.976
|
gene:Pan_g6554
|
sphingosine and sphingosine-1-phosphate metabolism
|
26-Feb-2015
|
|
gene:Pan_g750
|
3.1.3.-
|
0.931
|
gene:Pan_g750
|
3-phosphoinositide biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g750
|
3.1.3.-
|
0.931
|
gene:Pan_g750
|
3-phosphoinositide biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g18468
|
1.11.1.12
|
0.998
|
gene:Pan_g18468
|
glutathione redox reactions I
|
26-Feb-2015
|
|
gene:Pan_g5082
|
2.7.1.150
|
0.990
|
gene:Pan_g5082
|
3-phosphoinositide biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g15405
|
2.7.1.154
|
0.996
|
gene:Pan_g15405
|
3-phosphoinositide biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g15405
|
2.7.1.137
|
0.976
|
gene:Pan_g15405
|
3-phosphoinositide biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g7793
|
3.4.19.9
|
0.945
|
gene:Pan_g7793
|
4-hydroxy-2-nonenal detoxification
|
26-Feb-2015
|
|
gene:Pan_g698
|
3.1.3.57
|
1.000
|
gene:Pan_g698
|
D-myo-inositol (1,4,5)-trisphosphate degradation
|
26-Feb-2015
|
|
gene:Pan_g3291
|
3.1.6.12
|
0.966
|
gene:Pan_g3291
|
chondroitin sulfate degradation (metazoa)
|
26-Feb-2015
|
|
gene:Pan_g3291
|
3.1.6.12
|
0.966
|
gene:Pan_g3291
|
chondroitin sulfate degradation (metazoa)
|
26-Feb-2015
|
|
gene:Pan_g15438
|
none
|
0.997
|
gene:Pan_g15438
|
folate transformations I,
formylTHF biosynthesis I
|
26-Feb-2015
|
|
gene:Pan_g15438
|
none
|
0.997
|
gene:Pan_g15438
|
folate transformations I,
formylTHF biosynthesis I
|
26-Feb-2015
|
|
gene:Pan_g14433
|
2.7.7.75
|
1.000
|
gene:Pan_g14433
|
molybdenum cofactor biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g5869
|
3.5.2.9
|
0.997
|
gene:Pan_g5869
|
gamma-glutamyl cycle
|
26-Feb-2015
|
|
gene:Pan_g5869
|
3.5.2.9
|
0.997
|
gene:Pan_g5869
|
gamma-glutamyl cycle
|
26-Feb-2015
|
|
gene:Pan_g13590
|
6.3.2.5
|
0.997
|
gene:Pan_g13590
|
coenzyme A biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g23195
|
2.6.1.39
|
0.936
|
gene:Pan_g23195
|
lysine degradation II
|
26-Feb-2015
|
|
gene:Pan_g23195
|
2.6.1.39
|
0.936
|
gene:Pan_g23195
|
lysine degradation II
|
26-Feb-2015
|
|
gene:Pan_g23229
|
1.2.1.25
|
0.998
|
gene:Pan_g23229
|
valine degradation I
|
26-Feb-2015
|
|
gene:Pan_g23229
|
1.2.1.-
|
0.998
|
gene:Pan_g23229
|
isoleucine degradation I
|
26-Feb-2015
|
|
gene:Pan_g23229
|
1.2.1.-
|
0.994
|
gene:Pan_g23229
|
leucine degradation I
|
26-Feb-2015
|
|
gene:Pan_g21539
|
1.1.1.38
|
0.984
|
gene:Pan_g21539
|
chitin degradation to ethanol
|
26-Feb-2015
|
|
gene:Pan_g21539
|
1.1.1.38
|
0.984
|
gene:Pan_g21539
|
chitin degradation to ethanol
|
26-Feb-2015
|
|
gene:Pan_g17757
|
3.1.3.-
|
0.909
|
gene:Pan_g17757
|
3-phosphoinositide degradation
|
26-Feb-2015
|
|
gene:Pan_g17757
|
3.1.3.-
|
0.909
|
gene:Pan_g17757
|
3-phosphoinositide degradation
|
26-Feb-2015
|
|
gene:Pan_g1632
|
5.3.3.-
|
0.964
|
gene:Pan_g1632
|
fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)
|
26-Feb-2015
|
|
gene:Pan_g1632
|
5.3.3.-
|
0.964
|
gene:Pan_g1632
|
fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)
|
26-Feb-2015
|
|
gene:Pan_g23111
|
4.1.1.33
|
0.979
|
gene:Pan_g23111
|
mevalonate pathway I
|
26-Feb-2015
|
|
gene:Pan_g23111
|
4.1.1.33
|
0.979
|
gene:Pan_g23111
|
mevalonate pathway I
|
26-Feb-2015
|
|
gene:Pan_g3528
|
none
|
0.909
|
gene:Pan_g3528
|
tetrahydrobiopterin biosynthesis II
|
26-Feb-2015
|
|
gene:Pan_g3528
|
none
|
0.909
|
gene:Pan_g3528
|
tetrahydrobiopterin biosynthesis II
|
26-Feb-2015
|
|
gene:Pan_g23579
|
3.6.1.15
|
0.916
|
gene:Pan_g23579
|
pyrimidine deoxyribonucleotides biosynthesis from CTP,
pyrimidine deoxyribonucleotides de novo biosynthesis I
|
26-Feb-2015
|
|
gene:Pan_g23579
|
3.6.1.15
|
0.916
|
gene:Pan_g23579
|
pyrimidine deoxyribonucleotides biosynthesis from CTP,
pyrimidine deoxyribonucleotides de novo biosynthesis I
|
26-Feb-2015
|
|
gene:Pan_g24118
|
none
|
0.999
|
gene:Pan_g24118
|
arginine biosynthesis IV,
L-Ndelta-acetylornithine biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g24069
|
5.1.2.3
|
1.000
|
gene:Pan_g24069
|
fatty acid beta-oxidation I
|
26-Feb-2015
|
|
gene:Pan_g24069
|
5.3.3.8
|
1.000
|
gene:Pan_g24069
|
fatty acid beta-oxidation I
|
26-Feb-2015
|
|
gene:Pan_g19283
|
2.7.1.153
|
0.995
|
gene:Pan_g19283
|
3-phosphoinositide biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g19283
|
2.7.1.153
|
0.995
|
gene:Pan_g19283
|
3-phosphoinositide biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g19361
|
2.6.1.88
|
0.941
|
gene:Pan_g19361
|
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I
|
26-Feb-2015
|
|
gene:Pan_g19361
|
3.5.1.9
|
0.941
|
gene:Pan_g19361
|
tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde
|
26-Feb-2015
|
|
gene:Pan_g22440
|
4.1.99.18
|
0.978
|
gene:Pan_g22440
|
molybdenum cofactor biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g22440
|
4.1.99.18
|
0.978
|
gene:Pan_g22440
|
molybdenum cofactor biosynthesis
|
26-Feb-2015
|
|
gene:Pan_g8458
|
2.1.3.3
|
0.958
|
gene:Pan_g8458
|
arginine biosynthesis IV,
proline biosynthesis II (from arginine)
|
26-Feb-2015
|
|
gene:Pan_g8481
|
2.7.4.2
|
0.909
|
gene:Pan_g8481
|
mevalonate pathway I
|
26-Feb-2015
|
|
gene:Pan_g8481
|
2.7.4.2
|
0.909
|
gene:Pan_g8481
|
mevalonate pathway I
|
26-Feb-2015
|
|
gene:Pan_g17581
|
3.1.3.86
|
1.000
|
gene:Pan_g17581
|
3-phosphoinositide degradation
|
26-Feb-2015
|
|
gene:Pan_g17581
|
3.1.3.64
|
0.999
|
gene:Pan_g17581
|
3-phosphoinositide degradation
|
26-Feb-2015
|
|
gene:Pan_g17581
|
3.1.3.-
|
1.000
|
gene:Pan_g17581
|
3-phosphoinositide degradation
|
26-Feb-2015
|
|
gene:Pan_g17581
|
3.1.3.56
|
0.977
|
gene:Pan_g17581
|
D-myo-inositol (1,4,5)-trisphosphate degradation
|
26-Feb-2015
|