64 of 164 pathway holes were filled (39.0%).
|
Hole-filler
|
Hole EC#
|
P(has-function)
|
All functions of hole-filler
|
Pathway(s) requiring this reaction
|
Date filled
|
|
gene:MhA1_Contig665.frz3.gene5
|
2.7.1.2
|
0.989
|
gene:MhA1_Contig665.frz3.gene5
|
homolactic fermentation,
glycogen degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig718.frz3.gene5
|
1.1.1.35
|
1.000
|
gene:MhA1_Contig718.frz3.gene5
|
glutaryl-CoA degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig1390.frz3.gene3
|
2.7.7.80
|
0.990
|
gene:MhA1_Contig1390.frz3.gene3
|
molybdenum cofactor biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig1390.frz3.gene3
|
2.8.1.11
|
0.978
|
gene:MhA1_Contig1390.frz3.gene3
|
molybdenum cofactor biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig1390.frz3.gene3
|
2.7.7.80
|
0.990
|
gene:MhA1_Contig1390.frz3.gene3
|
molybdenum cofactor biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig1390.frz3.gene3
|
2.8.1.11
|
0.978
|
gene:MhA1_Contig1390.frz3.gene3
|
molybdenum cofactor biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig1939.frz3.fgene1
|
2.1.2.10
|
1.000
|
gene:MhA1_Contig1939.frz3.fgene1
|
glycine cleavage,
GCVMULTI-RXN
|
27-Feb-2015
|
|
gene:MhA1_Contig1939.frz3.fgene1
|
none
|
0.993
|
gene:MhA1_Contig1939.frz3.fgene1
|
formylTHF biosynthesis I
|
27-Feb-2015
|
|
gene:MhA1_Contig469.frz3.fgene1
|
1.8.1.4
|
0.975
|
gene:MhA1_Contig469.frz3.fgene1
|
pyruvate decarboxylation to acetyl CoA
|
27-Feb-2015
|
|
gene:MhA1_Contig469.frz3.fgene1
|
1.8.1.4
|
0.925
|
gene:MhA1_Contig469.frz3.fgene1
|
2-oxoisovalerate decarboxylation to isobutanoyl-CoA,
(S)-3-methyl-2-oxopentanoate dehydrogenase (acylating),
1.2.1.25-RXN,
4-methyl-2-oxopentanoate dehydrogenase (acylating)
|
27-Feb-2015
|
|
gene:MhA1_Contig469.frz3.fgene1
|
1.8.1.4
|
0.975
|
gene:MhA1_Contig469.frz3.fgene1
|
pyruvate decarboxylation to acetyl CoA
|
27-Feb-2015
|
|
gene:MhA1_Contig469.frz3.fgene1
|
1.8.1.4
|
0.925
|
gene:MhA1_Contig469.frz3.fgene1
|
2-oxoisovalerate decarboxylation to isobutanoyl-CoA,
(S)-3-methyl-2-oxopentanoate dehydrogenase (acylating),
1.2.1.25-RXN,
4-methyl-2-oxopentanoate dehydrogenase (acylating)
|
27-Feb-2015
|
|
gene:MhA1_Contig772.frz3.gene4
|
3.1.3.-
|
0.945
|
gene:MhA1_Contig772.frz3.gene4
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig772.frz3.gene4
|
3.1.3.-
|
0.945
|
gene:MhA1_Contig772.frz3.gene4
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig354.frz3.gene17
|
2.4.1.186
|
0.952
|
gene:MhA1_Contig354.frz3.gene17
|
glycogen biosynthesis II (from UDP-D-Glucose)
|
27-Feb-2015
|
|
gene:MhA1_Contig354.frz3.gene17
|
2.4.1.186
|
0.952
|
gene:MhA1_Contig354.frz3.gene17
|
glycogen biosynthesis II (from UDP-D-Glucose)
|
27-Feb-2015
|
|
gene:MhA1_Contig354.frz3.gene17
|
2.4.1.186
|
0.952
|
gene:MhA1_Contig354.frz3.gene17
|
glycogen biosynthesis II (from UDP-D-Glucose)
|
27-Feb-2015
|
|
gene:MhA1_Contig354.frz3.gene17
|
2.4.1.186
|
0.952
|
gene:MhA1_Contig354.frz3.gene17
|
glycogen biosynthesis II (from UDP-D-Glucose)
|
27-Feb-2015
|
|
gene:MhA1_Contig354.frz3.gene43
|
3.6.1.15
|
0.964
|
gene:MhA1_Contig354.frz3.gene43
|
pyrimidine deoxyribonucleotides de novo biosynthesis I,
pyrimidine deoxyribonucleotides biosynthesis from CTP
|
27-Feb-2015
|
|
gene:MhA1_Contig354.frz3.gene43
|
3.6.1.15
|
0.964
|
gene:MhA1_Contig354.frz3.gene43
|
pyrimidine deoxyribonucleotides de novo biosynthesis I,
pyrimidine deoxyribonucleotides biosynthesis from CTP
|
27-Feb-2015
|
|
gene:MhA1_Contig2322.frz3.gene3
|
2.3.1.168
|
0.967
|
gene:MhA1_Contig2322.frz3.gene3
|
2-oxoisovalerate decarboxylation to isobutanoyl-CoA,
1.2.1.25-RXN
|
27-Feb-2015
|
|
gene:MhA1_Contig2322.frz3.gene3
|
2.3.1.168
|
0.967
|
gene:MhA1_Contig2322.frz3.gene3
|
2-oxoisovalerate decarboxylation to isobutanoyl-CoA,
1.2.1.25-RXN
|
27-Feb-2015
|
|
gene:MhA1_Contig2444.frz3.gene1
|
1.1.1.300
|
0.955
|
gene:MhA1_Contig2444.frz3.gene1
|
retinol biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig2444.frz3.gene1
|
1.1.1.300
|
0.955
|
gene:MhA1_Contig2444.frz3.gene1
|
retinol biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig461.frz3.gene4
|
2.7.1.1
|
0.984
|
gene:MhA1_Contig461.frz3.gene4
|
glycolysis VI (mammalian)
|
27-Feb-2015
|
|
gene:MhA1_Contig461.frz3.gene4
|
2.7.1.1
|
0.984
|
gene:MhA1_Contig461.frz3.gene4
|
glycolysis VI (mammalian)
|
27-Feb-2015
|
|
gene:MhA1_Contig334.frz3.gene2
|
3.4.19.9
|
0.972
|
gene:MhA1_Contig334.frz3.gene2
|
4-hydroxy-2-nonenal detoxification
|
27-Feb-2015
|
|
gene:MhA1_Contig468.frz3.gene14
|
1.1.1.35
|
1.000
|
gene:MhA1_Contig468.frz3.gene14
|
fatty acid beta-oxidation I
|
27-Feb-2015
|
|
gene:MhA1_Contig468.frz3.gene14
|
5.1.2.3
|
1.000
|
gene:MhA1_Contig468.frz3.gene14
|
fatty acid beta-oxidation I
|
27-Feb-2015
|
|
gene:MhA1_Contig468.frz3.gene14
|
5.3.3.8
|
1.000
|
gene:MhA1_Contig468.frz3.gene14
|
fatty acid beta-oxidation I
|
27-Feb-2015
|
|
gene:MhA1_Contig468.frz3.gene14
|
3.1.2.4
|
1.000
|
gene:MhA1_Contig468.frz3.gene14
|
valine degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig147.frz3.fgene2
|
3.5.4.9
|
1.000
|
gene:MhA1_Contig147.frz3.fgene2
|
formylTHF biosynthesis I
|
27-Feb-2015
|
|
gene:MhA1_Contig147.frz3.fgene2
|
1.5.1.5
|
1.000
|
gene:MhA1_Contig147.frz3.fgene2
|
formylTHF biosynthesis I
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene13
|
1.1.1.330
|
0.984
|
gene:MhA1_Contig132.frz3.gene13
|
very long chain fatty acid biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene13
|
1.1.1.330
|
0.984
|
gene:MhA1_Contig132.frz3.gene13
|
very long chain fatty acid biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene13
|
1.1.1.330
|
0.984
|
gene:MhA1_Contig132.frz3.gene13
|
very long chain fatty acid biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene13
|
1.1.1.330
|
0.984
|
gene:MhA1_Contig132.frz3.gene13
|
very long chain fatty acid biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene13
|
1.1.1.330
|
0.984
|
gene:MhA1_Contig132.frz3.gene13
|
very long chain fatty acid biosynthesis I
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene13
|
1.1.1.330
|
0.984
|
gene:MhA1_Contig132.frz3.gene13
|
very long chain fatty acid biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene13
|
1.1.1.330
|
0.984
|
gene:MhA1_Contig132.frz3.gene13
|
very long chain fatty acid biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene13
|
1.1.1.330
|
0.984
|
gene:MhA1_Contig132.frz3.gene13
|
very long chain fatty acid biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene13
|
1.1.1.330
|
0.984
|
gene:MhA1_Contig132.frz3.gene13
|
very long chain fatty acid biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene13
|
1.1.1.330
|
0.984
|
gene:MhA1_Contig132.frz3.gene13
|
very long chain fatty acid biosynthesis I
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene27
|
1.1.1.38
|
0.941
|
gene:MhA1_Contig132.frz3.gene27
|
chitin degradation to ethanol
|
27-Feb-2015
|
|
gene:MhA1_Contig132.frz3.gene27
|
1.1.1.38
|
0.941
|
gene:MhA1_Contig132.frz3.gene27
|
chitin degradation to ethanol
|
27-Feb-2015
|
|
gene:MhA1_Contig684.frz3.gene27
|
4.1.1.70
|
0.978
|
gene:MhA1_Contig684.frz3.gene27
|
glutaryl-CoA degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig45.frz3.gene21
|
1.1.1.94
|
0.990
|
gene:MhA1_Contig45.frz3.gene21
|
CDP-diacylglycerol biosynthesis I
|
27-Feb-2015
|
|
gene:MhA1_Contig656.frz3.gene16
|
none
|
0.964
|
gene:MhA1_Contig656.frz3.gene16
|
tetrahydrobiopterin biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig656.frz3.gene16
|
none
|
0.964
|
gene:MhA1_Contig656.frz3.gene16
|
tetrahydrobiopterin biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig579.frz3.fgene2
|
4.2.1.22
|
0.949
|
gene:MhA1_Contig579.frz3.fgene2
|
cysteine biosynthesis/homocysteine degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig579.frz3.fgene2
|
4.2.1.22
|
0.949
|
gene:MhA1_Contig579.frz3.fgene2
|
cysteine biosynthesis/homocysteine degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig1032.frz3.fgene3
|
2.7.1.68
|
0.942
|
gene:MhA1_Contig1032.frz3.fgene3
|
D-myo-inositol (1,4,5)-trisphosphate biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig1032.frz3.fgene3
|
2.7.1.149
|
0.989
|
gene:MhA1_Contig1032.frz3.fgene3
|
D-myo-inositol (1,4,5)-trisphosphate biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig1032.frz3.fgene3
|
2.7.1.68
|
0.942
|
gene:MhA1_Contig1032.frz3.fgene3
|
D-myo-inositol (1,4,5)-trisphosphate biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig1032.frz3.fgene3
|
2.7.1.149
|
0.989
|
gene:MhA1_Contig1032.frz3.fgene3
|
D-myo-inositol (1,4,5)-trisphosphate biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig199.frz3.gene5
|
5.3.3.-
|
0.964
|
gene:MhA1_Contig199.frz3.gene5
|
fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)
|
27-Feb-2015
|
|
gene:MhA1_Contig199.frz3.gene5
|
5.3.3.-
|
0.964
|
gene:MhA1_Contig199.frz3.gene5
|
fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)
|
27-Feb-2015
|
|
gene:MhA1_Contig726.frz3.gene16
|
2.6.1.88
|
0.978
|
gene:MhA1_Contig726.frz3.gene16
|
S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig274.frz3.gene5
|
3.2.1.33
|
0.993
|
gene:MhA1_Contig274.frz3.gene5
|
glycogen degradation II
|
27-Feb-2015
|
|
gene:MhA1_Contig274.frz3.gene5
|
2.4.1.25
|
0.993
|
gene:MhA1_Contig274.frz3.gene5
|
glycogen degradation II
|
27-Feb-2015
|
|
gene:MhA1_Contig274.frz3.gene5
|
3.2.1.33
|
0.993
|
gene:MhA1_Contig274.frz3.gene5
|
glycogen degradation II
|
27-Feb-2015
|
|
gene:MhA1_Contig274.frz3.gene5
|
2.4.1.25
|
0.993
|
gene:MhA1_Contig274.frz3.gene5
|
glycogen degradation II
|
27-Feb-2015
|
|
gene:MhA1_Contig291.frz3.gene16
|
none
|
0.925
|
gene:MhA1_Contig291.frz3.gene16
|
diphthamide biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig291.frz3.gene16
|
none
|
0.925
|
gene:MhA1_Contig291.frz3.gene16
|
diphthamide biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig234.frz3.fgene2
|
3.4.13.18
|
0.968
|
gene:MhA1_Contig234.frz3.fgene2
|
gamma-glutamyl cycle
|
27-Feb-2015
|
|
gene:MhA1_Contig1095.frz3.gene5
|
3.1.3.67
|
0.956
|
gene:MhA1_Contig1095.frz3.gene5
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig1095.frz3.gene5
|
3.1.3.67
|
0.956
|
gene:MhA1_Contig1095.frz3.gene5
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig1095.frz3.gene5
|
3.1.3.67
|
0.956
|
gene:MhA1_Contig1095.frz3.gene5
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig1095.frz3.gene5
|
3.1.3.67
|
0.956
|
gene:MhA1_Contig1095.frz3.gene5
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig168.frz3.gene45
|
2.7.8.11
|
0.998
|
gene:MhA1_Contig168.frz3.gene45
|
D-myo-inositol (1,4,5)-trisphosphate biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig168.frz3.gene45
|
2.7.8.11
|
0.998
|
gene:MhA1_Contig168.frz3.gene45
|
D-myo-inositol (1,4,5)-trisphosphate biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig1238.frz3.gene9
|
2.7.7.23
|
0.991
|
gene:MhA1_Contig1238.frz3.gene9
|
UDP-N-acetyl-D-glucosamine biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig1238.frz3.gene9
|
2.7.7.23
|
0.991
|
gene:MhA1_Contig1238.frz3.gene9
|
UDP-N-acetyl-D-glucosamine biosynthesis II
|
27-Feb-2015
|
|
gene:MhA1_Contig1469.frz3.gene10
|
3.1.3.78
|
0.990
|
gene:MhA1_Contig1469.frz3.gene10
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig1469.frz3.gene10
|
3.1.3.78
|
0.990
|
gene:MhA1_Contig1469.frz3.gene10
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig1507.frz3.gene13
|
2.10.1.1
|
1.000
|
gene:MhA1_Contig1507.frz3.gene13
|
molybdenum cofactor biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig762.frz3.gene5
|
4.1.99.18
|
0.952
|
gene:MhA1_Contig762.frz3.gene5
|
molybdenum cofactor biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig762.frz3.gene5
|
4.1.99.18
|
0.952
|
gene:MhA1_Contig762.frz3.gene5
|
molybdenum cofactor biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig1535.frz3.gene3
|
1.2.1.25
|
0.997
|
gene:MhA1_Contig1535.frz3.gene3
|
valine degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig1535.frz3.gene3
|
1.2.1.-
|
0.997
|
gene:MhA1_Contig1535.frz3.gene3
|
isoleucine degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig1535.frz3.gene3
|
1.2.1.-
|
0.989
|
gene:MhA1_Contig1535.frz3.gene3
|
leucine degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig309.frz3.gene38
|
6.3.2.5
|
1.000
|
gene:MhA1_Contig309.frz3.gene38
|
coenzyme A biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig811.frz3.fgene1
|
2.4.2.10
|
1.000
|
gene:MhA1_Contig811.frz3.fgene1
|
UMP biosynthesis
|
27-Feb-2015
|
|
gene:MhA1_Contig42.frz3.gene21
|
3.1.3.86
|
1.000
|
gene:MhA1_Contig42.frz3.gene21
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig42.frz3.gene21
|
3.1.3.64
|
1.000
|
gene:MhA1_Contig42.frz3.gene21
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig42.frz3.gene21
|
3.1.3.-
|
1.000
|
gene:MhA1_Contig42.frz3.gene21
|
3-phosphoinositide degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig42.frz3.gene21
|
3.1.3.56
|
0.930
|
gene:MhA1_Contig42.frz3.gene21
|
D-myo-inositol (1,4,5)-trisphosphate degradation
|
27-Feb-2015
|
|
gene:MhA1_Contig410.frz3.gene6
|
2.2.1.6
|
0.947
|
gene:MhA1_Contig410.frz3.gene6
|
isoleucine biosynthesis I (from threonine)
|
27-Feb-2015
|
|
gene:MhA1_Contig410.frz3.gene6
|
2.2.1.6
|
0.947
|
gene:MhA1_Contig410.frz3.gene6
|
isoleucine biosynthesis I (from threonine)
|
27-Feb-2015
|
|
gene:MhA1_Contig658.frz3.gene7
|
2.3.1.9
|
0.998
|
gene:MhA1_Contig658.frz3.gene7
|
isoleucine degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig658.frz3.gene7
|
2.3.1.9
|
0.998
|
gene:MhA1_Contig658.frz3.gene7
|
glutaryl-CoA degradation,
mevalonate pathway I
|
27-Feb-2015
|
|
gene:MhA1_Contig1833.frz3.fgene1
|
2.6.1.7
|
0.973
|
gene:MhA1_Contig1833.frz3.fgene1
|
tryptophan degradation XI (mammalian, via kynurenine)
|
27-Feb-2015
|
|
gene:MhA1_Contig546.frz3.gene1
|
1.3.8.-
|
0.997
|
gene:MhA1_Contig546.frz3.gene1
|
valine degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig546.frz3.gene1
|
1.3.8.5
|
0.997
|
gene:MhA1_Contig546.frz3.gene1
|
isoleucine degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig546.frz3.gene1
|
1.3.8.-
|
0.997
|
gene:MhA1_Contig546.frz3.gene1
|
valine degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig546.frz3.gene1
|
1.3.8.5
|
0.997
|
gene:MhA1_Contig546.frz3.gene1
|
isoleucine degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig815.frz3.fgene1
|
3.5.2.9
|
0.993
|
gene:MhA1_Contig815.frz3.fgene1
|
gamma-glutamyl cycle
|
27-Feb-2015
|
|
gene:MhA1_Contig815.frz3.fgene1
|
3.5.2.9
|
0.993
|
gene:MhA1_Contig815.frz3.fgene1
|
gamma-glutamyl cycle
|
27-Feb-2015
|
|
gene:MhA1_Contig530.frz3.gene8
|
1.1.1.178
|
0.985
|
gene:MhA1_Contig530.frz3.gene8
|
isoleucine degradation I
|
27-Feb-2015
|
|
gene:MhA1_Contig530.frz3.gene8
|
1.1.1.178
|
0.985
|
gene:MhA1_Contig530.frz3.gene8
|
isoleucine degradation I
|
27-Feb-2015
|