TABLES.CHR2_ORFS.TXT ****************************************************************************************************************************** NOTE: Please set terminal width to 132 characters/line and edit (VMS eve) to read properly !!!! ****************************************************************************************************************************** The content of this file is part of the data unraveled by a consortium of European laboratories supported by the Commission of the European Union in the framework of sequencing yeast chromosome II. H. Feldmann et al. (1994) ' Complete sequence of yeast chromosome II', submitted The dataset was developed in collaboration of H.W. Mewes Martinsried Institute for Protein Sequences (MIPS) Max-Planck-Institut fuer Biochemie, 85152 Martinsried, Germany Telephone:+49 89 8578 2656 FAX +49 89 8578 2655 e-mail mewes@ehpmic.mips.biochem.mpg.de e-mail mewes@mips.embnet.org and Horst Feldmann Institut fuer Physiologische Chemie, Universitaet Muenchen, Schillerstrasse 44, 80336 Muenchen, Germany Telephone:+49 89 5996 451 FAX +49 89 5996 316 e-mail feldmann@dec1.bio.med.uni-muenchen.de >>> The data may be used for scientific purposes under the condition that the proper reference is given. <<< We have made every effort to ensure liability of the data and cannot be responsible for the consequences to users of any errors resulting from its use. ********************************************************************************************************************************** Table 3. Yeast chromosome II: Open reading frames __________________________________________________________________________________________________________________________________ System. MIPS Coordinates ORF Gene Function Put. ORF working begin end length name TM nomencl.nomencl. spans __________________________________________________________________________________________________________________________________ YBL108w YBL0801w 2223 2525 101 / Homolog to YKL223w; YCR103c / YBL107c YBL0805c 4010 4597 196 YBL106c YBL0806c 4896 7925 1010 Probable ß-transducin, mouse mgl1 homolog 5 YBL105c YBL0807c 8290 11742 1151 PKC1 Protein kinase-C like protein, ser/thr-specific (EC 2.7.1.37) 2 YBL104c YBL0808c 12366 15140 925 1 YBL103c YBL0810c 16628 17575 316 Probable cytochrome c subunit, copper binding YBL102w YBL0812 18138 18782 215 4 YBL101c YBL0814c 18989 22219 1077 YBL000 YBL0821w 23968 25281 438 TY2A YBL000 YBL0822w 23968 29278 1770t TY2B YBL100c YBL0826c ov 31025 31336 104 2 YBL099w YBL0827w 31086 32720 545 ATP1 Mitochondrial ATPase, alpha chain precursor (EC 3.6.1.34) YBL098w YBL0828w 33178 34557 460 2 YBL097w YBL0830w 34944 37127 728 YBL096c YBL0834c ov 37212 37517 102 2 YBL095w YBL0835w 37312 38121 270 2 YBL094c YBL0836c ov 37803 38132 110 2 YBL093c YBL0837c 38294 38953 220 ROX3 Essential nuclear protein involved in CYC7 expression YBL092w YBL0838w 40013 40402 130i [RPL32.e] Probable ribosomal protein L32.e YBL091c YBL0701c 41401 42447 349 Probable IF2-associated glycoprotein YBL090w YBL0702w 42860 43390 177§ YBL089w YBL0703w 43459 44985 509§ 10 YBL088c YBL0706c 45057 53417 2787 Probable phosphatidylinositol kinase, homolog of DRR1 (S. cerevisiae) 10 YBL087c YBL0713c 53859 54773 137i RPL17A Probable ribosomal protein L23.e or YL17a YBL086c YBL0714c 55240 56637 466 YBL085w YBL0717w 57911 60850 980 BOB1 BEM1-binding protein YBL084c YBL0718c 61207 63480 758 CDC27 Cell division control protein CDC27 YBL083c YBL0719c ov 63751 64173 141 YBL082c YBL0720c 63789 65162 458 10 YBL081w YBL0722w 65901 67004 368 YBL080c YBL0724c 67108 68730 541 PET112 Factor essential for maintenance of rho+ mitochondrial DNA 1 YBL079w YBL0725w 69294 73799 1502 6 YBL078c YBL0732c 74416 74766 117 YBL077w YBL0733w ov 74933 75361 143 YBL076c YBL0734c 75082 78297 1072 ILS1 Isoleucyl tRNA synthetase (EC 6.1.1.5) YBL075c YBL0610c 78538 80484 649 SSA3 Heat shock protein, 70 kDa YBL074c YBL0611c 80761 81825 355 AAR2 MATa1-mRNA splicing factor YBL073w YBL0612w ov 81682 81990 103 2 YBL072c YBL0613c 82562 83161 200i RPS8 Ribosomal protein S8.e YBL071c YBL0615c 84262 84567 102 1 YBL070c YBL0616c ov 84644 84961 106 3 YBL069w YBL0617w 84777 85760 328 / Homology to quinone oxidoreductase (E. coli) / YBL068w YBL0619w 86367 87431 355 [PRPS3] Probable ribose-phosphate pyrophosphokinase 1 YBL067c YBL0621c 87859 89922 688 YBL066c YBL0501c 90948 94118 1057 Probable regulatory Zn-finger protein 3 YBL065w YBL0502w ov 93966 94307 114 2 YBL064c YBL0503c 94377 95159 261 Homolog to thiol-specific antioxidant YBL063w YBL0504w 95889 99221 1111 KIP1 Kinesin-related protein YBL062w YBL0505w ov 99311 99688 126 2 YBL061c YBL0506c 99322 101409 696 SKT5 Probable Ca++ binding membrane protein (prenylated) YBL060w YBL0507w 101935 103995 687 YBL059w YBL0508w 104597 105247 193i 2 YBL058w YBL0509w 105440 106708 423 YBL057c YBL0510c 106807 107448 214 YBL056w YBL0511w 107766 109169 468 Probable phosphoprotein (ser/thr) phosphatase YBL055c YBL0512c 109580 110833 418 YBL054w YBL0513w 111593 113167 525 Homolog to myb transforming proteins YBL053w YBL0514w ov 113339 113710 124 1 YBL052c YBL0515c 113386 115878 831 / Homology to human HLA-associated protein I / YBL051c YBL0516c 116760 118763 668 / Homology to RNP-binding proteins / YBL050w YBL0517w 119129 120120 292i SEC17 Transport vesicle fusion protein (SNAP protein) YBL049w YBL0518w 120832 121245 138§ YBL048w YBL0519w 121303 121611 103§ 3 YBL047c YBL0520c 121902 126044 1381 USO1 homolog (S. cerevisiae), cytoskeletal-related transport protein, Ca++ binding 1 YBL046w YBL0402w 126428 127750 441 YBL045c YBL0403c 128150 129520 457 COR1 Ubiquinol-cytochrome c reductase (EC 1.10.2.2) YBL044w YBL0404w 130002 130367 122 YBL043w YBL0405w 130692 131462 257 YBL042c YBL0406c 132348 134264 639 Homolog to FUR4 , uracil transport protein (S.cerevisiae) 12 YBL041w YBL0407w 135251 135973 241 PRS3 Proteasome subunit 3 (multicatalytic endopeptidase complex, EC 3.4.99.46) YBL040c YBL0408c 136119 136872 219i ERD2 ER lumen protein retaining receptor 6 YBL039c YBL0410c 137996 139732 579 URA7 Cytidine triphosphate synthase (EC 6.3.4.2) 3 YBL038w YBL0411w 140191 140886 232 [MRPL16] Probable mitochondrial ribosomal protein L16 YBL037w YBL0412w 141213 144287 1025 / Homology to mouse alpha adaptin protein(s) / 4 YBL036c YBL0413c 144454 145224 257 Homolog to twitching motility protein (P. aeroginosa) YBL035c YBL0414c 145500 147614 705 / Homology to human DNA polymerase alpha, chain B / 1 YBL034c YBL0416c 147855 152393 1513 YBL033c YBL0417c 152663 153697 345 [RIB1] Probable GTP cyclohydrolase II YBL032w YBL0418w 154188 155330 381 YBL031w YBL0420w 155703 156716 338 YBL030c YBL0421c 157048 158001 318 AAC2 Mitochondrial ATP/ADP carrier 4 YBL029w YBL0423w 160138 161265 376 YBL028c YBL0424c 161525 161842 106 YBL027w YBL0425w 162427 163377 189i RPL19 Ribosomal protein L19.e YBL026w YBL0425aw 164627 165039 95i Probable snRNP-related protein YBL025w YBL0426w 165485 165919 145 YBL024w YBL0437w 166538 168589 684 Probable proliferating-cell nucleolar antigen (human p120) YBL023c YBL0438c 168927 171530 868 MCM2 Minichromosome maintenance protein, transcription factor YBL022c YBL0440c 171881 175279 1133 PIM1 Mitochondrial ATP-dependent lon-like serine proteinase precursor YBL021c YBL0441c 175667 176098 144 HAP3 Nuclear factor regulating respiratory and catabolite genes YBL020w YBL0442w 176405 178126 574 / Homology to AP endonuclease / 12 YBL019w YBL0443w 178357 179916 520 1 YBL018c YBL0301c 180005 180478 133i§ YBL017c YBL0302c 180851 185587 1579 PEP1 Carboxypeptidase Y sorting precursor (transmembrane protein) 3 YBL016w YBL0303w 186455 187513 353 FUS3 Protein kinase with a positive role in the cell cycle and in cell fusion (EC 2.7.1.-) YBL015w YBL0304w 188126 189703 526 ACH1 Acetyl-CoA hydrolase (EC 3.1.2.1) YBL014c YBL0311c 193071 195752 894 YBL013w YBL0313w 196060 197238 393 Probable met-tRNA formyltransferase, mitochondrial YBL012c YBL0314c ov 197412 197810 133 2 YBL011w YBL0315w 197541 199817 759 / Homolog to YKR067w / 3-6 YBL010c YBL0316c 200113 200952 280 YBL009w YBL0317w 201197 203224 676 YBL008w YBL0318w 203656 206175 840 HIR1 Regulator of histone gene transcription YBL007c YBL0321c 206638 210369 1244 SLA1 Cytoskeleton assembly control protein YBL006c YBL0322c 210699 211133 145 YBL005w YBL0323w 211474 214401 976 PDR3 Pleiotropic drug resistance protein 3 2 YBL000 YBL0324w 215334 216653 440 TY1A YBL000 YBL0325w 215334 220599 1755t TY1B YBL004w YBL0101w 221640 229118 2493 12 YBL003c YBL0103c 229401 229796 132 HTA2 Histone H2A.2 YBL002w YBL0104w 230496 230888 131 HTB2 Histone H2B.2 YBL001c YBL0105c 231159 231470 104 YBR001c YBR0106c 232947 235286 780 NTH2 a,a-trehalase (EC 3.2.1.28) YBR002c YBR0107c 235714 236571 286 YBR003w YBR0109w 236812 238230 473 COQ1 Hexaprenyl-pyrophosphate synthase precursor (EC 2.5.1.33) YBR004c YBR0110c 238372 239670 433 8 YBR005w YBR0111w 239909 240547 213 1 YBR006w YBR0112w 241013 242317 435 Probable aldehyde dehydrogenase (EC 1.2.1.-) YBR007c YBR0113c 242811 245018 736 YBR008c YBR0120c 246568 248211 548 Probable benomyl/methotrexate resistance protein 13 YBR009c YBR0122c 249375 249683 103 HHF1 Histone H4 YBR010w YBR0201w 250330 250737 136 HHT1 Histone H3 YBR011c YBR0202c 251114 251974 287 IPP1 Inorganic pyrophosphatase (EC 3.6.1.1) YBR012c YBR0205c 253149 253565 139 YBR000 YBR0206w 253868 255187 440 TY1A YBR000 YBR0207w 253868 259136 1756t TY1B YBR013c YBR0209c 259494 259880 129 1 YBR014c YBR0219c 260729 261337 203 Glutaredoxin homolog 1 YBR015c YBR0220c 261714 263504 597 TPP1 'Type II transmembrane protein' 1-3 YBR016w YBR0222w 264248 264631 128 1 YBR017c YBR0224c 264951 267704 918 / Homology to GCN1 (S. cerevisiae), ATP-binding / YBR018c YBR0226c 268431 269528 366 GAL7 Galactose-1-phosphate uridylyltransferase (EC 2.7.7.12) 1 YBR019c YBR0301c 270257 272353 699 GAL10 UDP-glucose-4-epimerase (EC 5.1.3.2) YBR020w YBR0302w 273022 274605 528 GAL1 Galactokinase (EC 2.7.1.6) 3 YBR021w YBR0303w 275444 277342 633 FUR4 Uracil transport protein 10-12 YBR022w YBR0304w 277739 278269 177 YBR023c YBR0305c 278432 281926 1165 CHS3 Chitin synthase 3 (EC 2.4.1.16) 8 YBR024w YBR0308w 283446 284348 301 [SCO2] SCO1 protein homolog (S. cerevisiae) YBR025c YBR0309c 284685 285866 394 Probable purine nucleotide-binding protein YBR026c YBR0310c 286881 288020 380§ [MRF1] Probable (mitochondrial) ssDNA-binding protein YBR027c YBR0311c 288028 288357 110 2 YBR028c YBR0312c 288429 290003 525 Probable ser/thr-specific protein kinase, homolog to YKR2 and YPK1 (S. cerevisiae) YBR029c YBR0313c 290373 291743 457 / Homology to cytochrome c oxidase (T. brucei) / 6 YBR030w YBR0314w 292293 293948 552 / Homology to SIN3 (S. cerevisiae) (weak) / YBR031w YBR0315w 294167 295252 362 RPL2 Ribosomal protein L2.A YBR032w YBR0317w 295520 295819 100 YBR033w YBR0318w 295945 298701 919 Probable regulatory Zn-finger protein, / homolog to YKL251/ 5 YBR034c YBR0320c 298934 299977 348 ODP1 ORF distal from PDX3 1 YBR035c YBR0321c 300273 300956 228 PDX3 Pyridoxamine-phosphate oxidase (EC 1.4.3.5) YBR036c YBR0404c 303085 304314 410 CSG2 Ca2++ -dependent regulatory protein 10 YBR037c YBR0406c 304568 305452 295 SCO1 Cytochrome oxidase assembly protein precursor 1 YBR038w YBR0407w 305898 308786 963 CHS2 Chitin synthase 2 (EC 2.4.1.16) 8 YBR039w YBR0408w 309576 310508 311 ATP3 Probable H+ -transporting ATPase / Homolog to bovine F(1)-ATPase gamma chain / YBR040w YBR0410w 310969 311862 298 5 YBR041w YBR0411w 312267 314135 623 Probable AMP-binding protein 4 YBR042c YBR0412c 314422 315612 397 Probable membrane-bound small GTPase 4 YBR043c YBR0413c 315882 317948 689 / Homology to benomyl/methotrexate resistance protein / 11 YBR044c YBR0414c 318343 320061 573 / Homology to mitochondrial chaperonin hsp60 / 1 YBR045c YBR0420c 322375 324093 573 YBR046c YBR0421c 324511 325512 334 Homolog to quinone oxidoreductase (E. coli) 2 YBR047w YBR0422w 325834 326358 175 YBR048w YBR0501w 326832 327813 156i RPS18B Ribosomal protein S11.e.B YBR049c YBR0502c 328390 330819 810 REB1 DNA-binding regulatory protein YBR050c YBR0504c 331187 332200 338 YBR051w YBR0504awo 331989 332336 116 3 YBR052c YBR0505c 332724 333353 210 Homolog to YCR004, obr1 (S. pombe), trp repressor binding protein (E. coli) YBR053c YBR0506c 333679 334752 358 YBR054w YBR0507w 337102 338133 344 [YRO2] Homolog to HSP30 heat shock protein YRO1 (S. cerevisiae) 7 YBR055c YBR0508c 338606 341302 899 PRP6 Pre-mRNA splicing factor YBR056w YBR0510w 341880 343382 501§ Homolog to glucan-1,3-ß-glucosidase (EC 3.2.1.5; S. cerevisiae) 2 YBR057c YBR0514c 346197 347294 366 YBR058c YBR0515c 347676 350084 803 / Homology to human transforming protein (weak) / YBR059c YBR0519c 350865 354188 1108 Probable protein kinase YBR060c YBR0523c 354656 356515 620 RRR1 Origin recognition complex, 72 kDa subunit YBR061c YBR0527c 358791 359720 310 Homolog to ftsJ protein (E. coli) , / YCR054 / YBR062c YBR0528c 359980 360324 115 YBR063c YBR0610c 360975 362186 404 Probable phosphopanthethein-binding protein 1 YBR064w YBR0612w ov 361765 362190 142 3 YBR065c YBR0614c 362589 363680 364 YBR066c YBR0616c 364042 364701 220 Probable Zn-finger protein YBR067c YBR0622c 366107 366736 210 TIP1 Temp. shock-inducible protein precursor SRP1/TIP1 1-2 YBR068c YBR0629c 367865 369691 609 Probable amino acid transport protein 12 YBR069c YBR0710c 370578 372434 619 Probable amino acid transport protein 12 YBR070c YBR0711c 373224 373934 237 3 YBR071w YBR0712w 374411 375043 211 YBR072w YBR0714w 376030 376671 214 HSP26 Heat shock protein, 30 kDa YBR073w YBR0715w 377110 379983 958 Probable RAD protein (S. cerevisiae), DNA repair helicase 3 YBR074w YBR0718w 380284 381522 413 Homolog to aminopeptidase Y (S. cerevisiae) 3 YBR075w YBR0719w 381834 383213 460 3 YBR076w YBR0722w 384374 385390 339 YBR077c YBR0723c 385807 386292 162 1 YBR078w YBR0727w 387123 388130 226i§ Homolog to sporulation specific protein SPS2 (S. cerevisiae) YBR079c YBR0734c 389391 392282 964 YBR080c YBR0736c 392622 394895 758 SEC18 Vesicular fusion protein YBR081c YBR0739c 395261 399256 1332 SPT7 Probable transcription factor, suppressor of Ty transcription YBR082c YBR0745c 400636 401128 148i UBC4 Ubiquitin conjugating enzyme E2, 16 kD subunit (EC 6.2.3.19) YBR083w YBR0750w 403174 404631 486 TEC1 Ty transcription activator YBR084w YBR0751w 405059 407983 975 MIS1 C1-tetrahydrofolate synthase precursor, mitochondrial 6 YBR085w YBR0753w 409988 410908 307 AAC3 Mitochondrial ATP/ADP carrier 4 YBR086c YBR0809c 414209 417046 946 Probable transmembrane protein 7-9 YBR087w YBR0810w 417770 418831 354 Replication factor RFC3 homolog 3 YBR088c YBR0811c 418998 419771 258 POL30 Proliferating cell nuclear antigen YBR089w YBR0811awo 419188 419784 199 2 YBR090c YBR0811bc 420382 421062 108i 1 YBR091c YBR0812c 421162 421488 109 MRS5 Nuclear protein involved in mitochondrial intron splicing YBR092c YBR0813c 421705 423105 467 PHO3 Acidic phosphatase, constitutive (EC 3.1.3.2) YBR093c YBR0814c 423555 424955 467 PHO5 Acidic phosphatase, repressible (EC 3.1.3.2) YBR094w YBR0821w 426040 428298 753 / Homology to porcine tubulin-tyrosine ligase / YBR095c YBR0822c 428413 429771 453 / Homology to cyclin B / YBR096w YBR0824w 430025 430714 230 YBR097w YBR0825w 430955 435316 1454 VPS15 Protein kinase essential for delivery of hydrolases to the vacuole 8 YBR098w YBR0826w 435519 436931 471 / Homology to clathrin , heavy chain / YBR099c YBR0828c ov 436932 437312 127 3 YBR100w YBR0829w 437257 437592 112 YBR101c YBR0830c 437829 438698 290 /Homology to Ytb/rab interacting protein / YBR102c YBR0831c 439070 441328 753 / Homology to myosin-like protein MLP1 / 1 YBR103w YBR0832w 441714 443318 535 / Homology to human LIS-1 protein, C-type lectin / 1 YBR104w YBR0833w 443672 444658 329 [YMC2] Mitochondrial carrier protein 4 YBR105c YBR0834c 444889 445974 362 YBR106w YBR0835w 446663 447226 188 YBR107c YBR0836c 447801 448535 245 / Homology to chitin synthase / YBR108w YBR0901w 448827 451370 848 Probable transcription factor YBR109c YBR0904c 451926 452366 147 CMD1 Calmodulin YBR110w YBR0906w 452876 454222 449 ALG1 a-Mannosyltransferase (EC 2.4.1.-) 4 YBR111c YBR0907c 455185 455877 231 [YSA1] Homolog to serendipity protein (D. melanogaster) YBR112c YBR0908c 456877 459774 966 SSN6 Transcription regulatory protein YBR113w YBR0908ewo 459570 460049 160 3 YBR114w YBR0909w 461252 463621 790 RAD16 Radiation repair protein, putative DNA helicase YBR115c YBR0910c 463755 467930 1392 LYS2 a-Aminoadipate reductase (EC 1.2.1.31) 3 YBR116c YBR0911c ov 468206 468730 175§ 2 YBR117c YBR0912c 468399 470441 681 TKL2 Transketolase 2 (EC 2.2.1.1) YBR118w YBR0913w 471675 473048 458 TEF2 Translational elongation factor alpha-1 2 YBR119w YBR0915w 473342 474324 298i MUD1 U1snRNP-specific A protein YBR120c YBR0916c 474442 474927 162 CBP6 Cytochrome B pre-mRNA processing protein 6 YBR121c YBR0917c 475371 477371 667 [GRS1] Probable glycyl-tRNA synthase (EC 2.7.7.6) YBR122c YBR0918c 477977 478564 196 MRPL36 Mitochondrial ribosomal protein YmL36 YBR123c YBR0919c 478749 480695 649 TFC1 Transcription factor TFIIIC, 95 kDa subunit YBR124w YBR0920bwo 480511 480867 119 3 YBR125c YBR0921c 481206 482384 393 Probable phosphoprotein phosphatase (EC 3.1.3.16) YBR126c YBR0922c 482912 484396 495 CIF1 a,a-trehalose-phosphate synthase (EC 2.4.1.15) TPS1 YBR127c YBR1002c 485276 486826 517 ATPvs H+-transporting ATPase, vacuolar (EC 3.6.1.35) YBR128c YBR1003c 487088 488119 344 YBR129c YBR1004c 488360 489343 328 YBR130c YBR1005c 489599 490873 425 YBR131w YBR1006w 491167 493278 704 3 YBR132c YBR1007c 493659 495446 596 Probable amino acid transport protein 12 YBR133c YBR1008c 495811 498291 827 / Homology to DUR1,2 (S. cerevisiae) / 3 YBR134w YBR1010wov 498247 498645 133 YBR135w YBR1011w 498858 499307 150 CKS1 CDC28 kinase complex, regulatory subunit YBR136w YBR1012w 499672 506775 2368 Probable phosphoinosityl PI3 kinase, TOR2 homolog 9 YBR137w YBR1013w 507048 507584 179 YBR138c YBR1014c 507769 509340 524 YBR139w YBR1015w 509668 511191 508 Probable serine-type carboxypeptidase (EC 3.4.16.1) 1 YBR140c YBR1016c 511357 520632 3092 IRA1 GTPase-activating protein of the RAS-cAMP pathway 21 YBR141c YBR1118c 521032 522042 337 YBR142w YBR1119w 522321 524639 773 Probable pre-mRNA splicing RNA-helicase YBR143c YBR1120c 524876 526186 437 SUP1 Ominipotent suppressor protein of nonsense codons YBR144c YBR1121c 527242 527553 104 1 YBR145w YBR1122w 527766 528818 351 [ADH5] Alcohol dehydrogenase (EC 1.1.1.1) YBR146w YBR1123w 529264 530097 278 [MRPS9] Probable mitochondrial ribosomal protein S9 YBR147w YBR1124w 530579 531466 296 7 YBR148w YBR1125w 531880 533706 609 YBR149w YBR1127w 533991 535022 344 Probable aldehyde reductase (EC 1.1.1.21) YBR150c YBR1133c 535216 538497 1094 Probable Zn-finger protein 4 YBR151w YBR1201w 539032 539979 316 YBR152w YBR1202w 540380 541252 291 YBR153w YBR1203w 541464 542195 244 [RIB7] Riboflavin biosynthesis protein YBR154c YBR1204c 542369 543013 215 RPB5 RNA polymerases I,II, and III, 27 kDa subunit (ABC27) (EC 2.7.7.6) YBR155w YBR1205w 543775 544929 385 Stress-inducible riboflavin biosynthetic protein homolog YBR156c YBR1206c 545111 547204 698 YBR157c YBR1207c 547996 548313 106 YBR158w YBR1208w 550552 552198 549 / Homology to CNTF receptor alpha (C. elegans) / YBR159w YBR1209w 552688 553728 347 / Homology to 17-ß hydroxysteroid dehydrogenase / 4 YBR160w YBR1211w 554081 554974 298 CDC28 Cell division control protein (EC2.7.1.-), p34/cdc2+ protein equivalent YBR161w YBR1212w 555638 556765 376 Homolog to suppressor of reduced viability of starvation (SUR1, S. cerevisiae) 2 YBR162c YBR1213c 557210 558574 455 1 YBR163w YBR1215w 559727 561481 585§ / Homology to pre-tRNA processing factor PTA1 (S. cerevisiae) / YBR164c YBR1216c 561882 562430 183 ARF3 GTP-binding ADP-ribosylation factor 3 YBR165w YBR1217w 562856 563686 277§ 1 YBR166c YBR1218c 563849 565204 452 TYR1 Prephenate dehydrogenase (NADP+) (EC 1.3.1.13) YBR167c YBR1219c 565475 565894 140 YBR168w YBR1220w 566375 567613 413 4 YBR169c YBR1221c 567922 570000 693 SSE2 Heat-shock protein, 70 kDa YBR170c YBR1231c 570351 572090 580 NPL4 Suppressor of SEC63 (S.cerevisiae), novel ER translocation component YBR171w YBR1232w 572368 572985 206 HSS1 ER translocation complex subunit SEC66 2 YBR172c YBR1233c 573157 575526 790 SMY2 Kinesin-related protein suppressing myosin defects (MYO2) YBR173c YBR1234c 575733 576176 148 YBR174c YBR1236c ov 576345 576656 104 YBR175w YBR1237w 576412 577356 315 Probable GTP-binding protein YBR176w YBR1238w 577724 578659 312 Probable 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) YBR177c YBR1239c 578814 580166 451 Probable membrane receptor YBR178w YBR1240w ov 580075 580446 124 1 YBR179c YBR1241c 580554 583118 855 Probable purine nucleotide-binding protein 2 YBR180w YBR1242w 583745 585460 572 Probable resistance protein 12 YBR181c YBR1244c 585719 586778 236i RPS101 Ribosomal protein S6.e YBR182c YBR1245c 587513 588868 452 Probable DNA-binding transcription factor, Homolog to SRF/SL-2 1 YBR183w YBR1305w 590119 591066 316 / Homology to lic-1 protein (H. influenzae) / 6 YBR184w YBR1306w 591367 592935 523 YBR185c YBR1307c 593130 593963 278 YBR186w YBR1308w 594557 596164 536 Probable ATP-binding protein, YTA1 related protein 3 YBR187w YBR1310w 596638 597477 280 Probable membrane protein 6 YBR188c YBR1316c 597692 598111 140 YBR189w YBR1317w 598512 599509 195i SUP46 Suppressor, ribosomal protein S13 YBR190w YBR1318w 599970 600278 103 / Homology to glycosyl hydrolases / YBR191w YBR1401w 600274 601141 160i URP1 Ribosomal protein L21.e YBR192w YBR1402w 601656 602786 377 RIM2 Probable carrier protein, mitochondrial YBR193c YBR1403c 603089 603757 223 YBR194w YBR1405w 604042 604410 123 YBR195c YBR1406c 604621 605886 422 MSI1 Multicopy suppressor of IRA1, probable ß-transducin type YBR196c YBR1407c 606243 607904 554 PGI1 Phosphoglucose isomerase (EC 5.3.1.9) YBR197c YBR1410c 609210 609860 217 YBR198c YBR1411c 610134 612527 798 Probable transcription-associated factor protein, probable ß-transducin type 2 YBR199w YBR1412w 612913 614304 464 KTR4 a-1,2-mannosyltransferase homolog 1 YBR200w YBR1413w 614876 616528 551 BEM1 Bud emergence mediator 1 YBR201w YBR1414w 617792 618214 141 2 YBR202w YBR1441w 619777 622311 845 MCM3 protein homolog (S. cerevisiae) YBR203w YBR1443w 623173 625944 924 YBR204c YBR1444c 626262 627386 375 Probable serine-active lipase, peroxisomal (EX 3.1.1.-) 2 YBR205w YBR1445w 627627 628838 404 [KTR3] a-1,2-mannosyltransferase homolog 1 YBR206w YBR1447w ov 628606 628926 107 1 YBR207w YBR1448w 629151 630545 465 Probable membrane protein 5 YBR208c YBR1449c 630711 636215 1835 DUR1,2 Urea carboxylase (EC 6.3.4.6) 6 YBR209w YBR1451w 636588 636902 105 1 YBR210w YBR1457w 639555 639980 142 3 YBR211c YBR1458c 640166 641137 324 / Homology to PEP3 protein (S. cerevisiae) / YBR212w YBR1459w 641891 643906 672 RBP1 RNA-binding protein, negative growth regulatory protein NGR1 YBR213w YBR1461w 644373 645194 274 MET8 Effector in the expression of PAPS reductase and sulfite reductase YBR214w YBR1501w 645420 647000 527 YBR215w YBR1503w 647451 649319 623§ HPC2 Cell-cycle regulatory protein, Regulator of S-phase transcription of histone genes YBR216c YBR1505c 649584 651605 674 2 YBR217w YBR1506w 651837 652394 186 1 YBR218c YBR1507c 652715 656254 1180 PYC2 Pyruvate carboxylase 2 (EC 6.4.1.1) YBR219c YBR1509c ov 656507 657308 127i§ 3 YBR220c YBR1510c 657003 658682 560 / Homolog to E. coli ampG protein / 10 YBR221c YBR1511c 659161 660258 366 PDB1 Pyruvate dehydrogenase (lipoamide), ß chain precursor (EC 1.2.4.1) YBR222c YBR1512c 660728 662356 543 Probable AMP-binding protein 3 YBR223c YBR1520c 662671 664302 544 YBR224w YBR1521w ov 664130 664642 171 5 YBR225w YBR1522w 664632 667331 900 YBR226c YBR1523c ov 667163 667570 136§ YBR227c YBR1524c 667580 669139 520§ Homolog to ATP-binding protein clpX (E.coli) 3 YBR228w YBR1525w 669318 670229 304 YBR229c YBR1526c 670365 673226 954 Homolog to 1,4-a-glucosidase (S.cerevisiae) (EC 3.2.1.3) 3 YBR230c YBR1527c 673557 674055 134i§ 2 YBR231c YBR1529c 676187 677095 303 YBR232c YBR1530c ov 677381 677737 119 3 YBR233w YBR1531w 677433 678671 413 Homolog to human hnRNP complex K protein YBR234c YBR1532c 679446 680597 384 / Homology to MAK11 protein (S. cerevisiae) / YBR235w YBR1601w 680906 684265 1120 13 YBR236c YBR1602c 684391 685698 436 ABD1 Protein with mutational synergism related to BEM1 YBR237w YBR1603w 685974 688520 849 PRP5 Pre-mRNA processing protein, RNA helicase YBR238c YBR1608c 689115 691307 731 YBR239c YBR1622c 692362 693948 529 Probable Zn-finger protein YBR240c YBR1624c 694498 695847 450 Probable Zn-finger protein YBR241c YBR1625c 696597 698060 488 Probable sugar transport protein 10 YBR242w YBR1627w 698675 699388 238 Probable ATP/GTP-binding protein YBR243c YBR1628c 699455 700798 448 TUR1 UDP-N-acetylglucosamin-1-phosphate transferase (EC 2.7.8.-); tunicamycin resistance 13 YBR244w YBR1632w 701533 702018 162 Probable glutathione peroxidase (EC 1.11.1.9) YBR245c YBR1633c 702158 705586 1143 Homolog to SNF2/SWI2 DNA-binding regulatory protein 1 YBR246w YBR1634w 705597 706757 387 YBR247c YBR1635c 707013 708461 483 YBR248c YBR1640c 708816 710471 552 HIS7 Glutamine amido transferase (EC 2.4.2.-) 2 YBR249c YBR1701c 710891 712000 370 ARO4 2-deoxy-3-deoxyphosphoheptanoate aldolase (EC 4.1.2.15) YBR250w YBR1702w 713039 714607 523 YBR251w YBR1704w 715396 716316 307 [MRPS5] Probable mitochondrial ribosomal protein S5 YBR252w YBR1705w 716617 717057 147 DUT1 Mitochondrial dUTP pyrophosphatase (EC 3.6.1.23) YBR253w YBR1721w 717276 717638 121 YBR254c YBR1722c 717745 718269 175 Probable membrane protein YBR255w YBR1723w 718462 720543 694 2 YBR256c YBR1724c 721395 722108 238 RIB5 Riboflavin synthase a-chain (EC 2.5.1.9) YBR257w YBR1725w 722891 723727 279 YBR258c YBR1726c 723743 724168 142 YBR259w YBR1727w 724393 726456 688 / Homology to serine-type carboxypeptidase PCR1 (S. cerevisiae) / YBR260c YBR1728c 726648 728645 666 / Homology to human bcr (break-poin cluster) protein / YBR261c YBR1729c 728841 729536 232 YBR262c YBR1731c 729729 730046 106 YBR263w YBR1732w 730045 731739 565 [SHMT1] Serine hydroxymethyltransferase (EC 2.1.2.1) 1 YBR264c YBR1733c 731779 732432 218 Probable small GTP-binding protein YBR265w YBR1734w 732588 733547 320 Probable membrane protein 3 YBR266c YBR1735c ov 733836 734396 187 Probable membrane protein 3 YBR267w YBR1736w 734143 735027 295 Probable Zn-finger protein (C2H2 type) YBR268w YBR1736aw 735307 735621 105 MRPL37 Probable mitochondrial ribosomal protein L37 YBR269c YBR1737c 736193 736582 130 YBR270c YBR1738c 736770 738404 545 Probable ATP/GTP-binding protein 1 YBR271w YBR1739w 738858 740114 419 / Homology to Clostridium botulinum C1 toxin / 2 YBR272c YBR1740c 740370 741809 480 / Homology to MSH1 protein (S. cerevisiae) (weak) / 2 YBR273c YBR1741c 742070 743377 436 YBR274w YBR1742w 743600 745180 527 Probable protein kinase (growth factor & cytokine receptor family) YBR275c YBR1743c 745365 751112 1916 RIF1 RAP1-interacting regulatory protein 6 YBR276c YBR2013c 751630 754050 807 Probable tyrosine-specific protein phosphatase 5 YBR277c YBR2014c ov 754225 754623 133 3 YBR278w YBR2015w 754301 754903 201 DPB3 DNA-directed DNA polymerase, chain C (EC 2.7.7.7) YBR279w YBR2016w 755264 756598 445 YBR280c YBR2017c 756794 758719 642 / Homology to pheromone response pathway component SRM1/PRP20 / 2 YBR281c YBR2018c 758980 761613 878 Probable G-protein, ß-transducin type YBR282w YBR2019w 762247 762684 146 MRPL27 Mitochondrial ribosomal protein YmL27 YBR283c YBR2020c 762953 764422 490 Probable SEC61 protein homolog 12 YBR284w YBR2021w 765246 767636 797 / Homology to S. cerevisiae AMP deaminase / 2 YBR285w YBR2023w 767929 768360 144 YBR286w YBR2024w 768625 770316 564 Aminopeptidase Y YBR287w YBR2034w 770577 771857 427 8 YBR288c YBR2035c 772021 773469 483 YBR289w YBR2036w 773673 776387 905 SNF5 General transcriptional activator YBR290w YBR2037w 776597 777559 321 2 YBR291c YBR2039c 777682 778578 299 Probable mitochondrial carrier protein , uncoupling protein homolog 4 YBR292c YBR2040c 778711 779079 123 2 YBR293w YBR2109w 781011 782432 474 Probable multidrug resistance protein 13 YBR294w YBR2110w 783240 785816 859 Probable sulfate transport protein 12 YBR295w YBR2112w 786853 790500 1216 PCA1 P-type copper transporting ATPase 10 YBR296c YBR2113c 790805 792526 574 Homolog to phosphate-repressible phosphate permease 10 YBR297w YBR2115w 794527 795930 468 MAL3R Maltose fermentation regulatory protein YBR298c YBR2116c 796638 798479 614 MAL3T Maltose permease 9 YBR299w YBR2117w 799355 801106 584 MAL3S Maltase (EC 3.2.1.20) YBR300c YBR2120c ov 802607 803101 165 1 YBR301w YBR2120aw 803061 803420 120 YKL224 c homolog YBR302c YBR2121c 804347 805483 379 / Homolog to YKL219w / 4 _______________________________________________________________________________________________________________________________ NOTES: i, intron-containing ORF; for length and coordinates of intron, see Table 5; §, two alternative ORFs, one spliced according to Fondrat and Kalogeropoulos (1993) and one non-spliced, overlap in this region; in this listing, preference has been given to the longer ORF or to the one with the higher CAI value. 'ov' indicates overlapping ORFs. [ ] refer to preliminary gene names. Weaker homologies are soecified by / /.