Date_Added_to_Catalog PUBMEDID First_Author Date Journal Disease_Trait Region Chr_id Chr_pos Reported_Gene_s Mapped_gene Strongest_SNP_Risk_Allele SNPs Snp_id_current Context Intergenic Risk_Allele_Frequency p_Value OR_or_beta CHR BR_START BR_END SNP_CHR SNP_ID SNP_POS BETA P INTERCEPT R SD Q 04/29/2011 21459883 Villard E 04/01/2011 Eur Heart J Dilated cardiomyopathy 1p36.13 1 16299312 ZBTB17 ZBTB17 rs10927875-? rs10927875 10927875 intron 1 NR 1E-9 1.32 1 16321009 16321463 1 16299312 16299312 0.874820146868 1.33809002257E-5 -0.70171640816 0.568686634461 0.180764136556 0.002521813 10/02/2009 19734545 Need AC 09/04/2009 Hum Mol Genet Cognitive performance 1p36.13 1 16393357 FAM131C FAM131C rs9442235-? rs9442235 9442235 intron 1 0.42 6E-6 NR 1 16382555 16382998 1 16393357 16393357 0.536092855969 5.6393271214E-4 -0.575397943092 0.466249685946 0.145310322066 0.05000424 07/13/2011 21700265 Kullo IJ 06/22/2011 Am J Hum Genet Erythrocyte sedimentation rate 1p36.11 1 25570081 C1orf63 C1orf63 rs1043879-? rs1043879 1043879 missense 1 NR 2E-9 .09 1 25613738 25614140 1 25570081 25570081 0.702398790192 4.1934296576E-4 -0.345524643271 0.47565760147 0.185563075185 0.04001819 01/12/2009 19060911 Aulchenko YS 12/07/2008 Nat Genet Cholesterol, total 1p36.11 1 25768937 TMEM57 TMEM57 rs10903129-G rs10903129 10903129 intron 1 0.54 5E-10 .06 1 25732270 25732656 1 25768937 25768937 0.759865746034 2.39904834431E-5 -0.778903388928 0.55472255616 0.162818893688 0.004080718 07/13/2011 21700265 Kullo IJ 06/22/2011 Am J Hum Genet Erythrocyte sedimentation rate 1p36.11 1 25768937 TMEM57 TMEM57 rs10903129-? rs10903129 10903129 intron 1 NR 5E-13 .10 1 25732270 25732656 1 25768937 25768937 0.759865746034 2.39904834431E-5 -0.778903388928 0.55472255616 0.162818893688 0.004080718 01/25/2012 20686565 Teslovich TM 08/05/2010 Nature Cholesterol, total 1p36.11 1 25775733 TMEM57,LDLRAP1 TMEM57 rs12027135-A rs12027135 12027135 intron 1 0.47 4E-11 1.22 1 25732270 25732656 1 25775733 25775733 0.759865746034 2.39904834431E-5 -0.778903388928 0.55472255616 0.162818893688 0.004080718 01/25/2012 20686565 Teslovich TM 08/05/2010 Nature LDL cholesterol 1p36.11 1 25775733 TMEM57,LDLRAP1 TMEM57 rs12027135-A rs12027135 12027135 intron 1 0.47 1E-10 1.10 1 25732270 25732656 1 25775733 25775733 0.759865746034 2.39904834431E-5 -0.778903388928 0.55472255616 0.162818893688 0.004080718 01/25/2012 20686565 Teslovich TM 08/05/2010 Nature HDL cholesterol 1p34.3 1 40028180 MACF1,PABPC4 PABPC4 rs4660293-G rs4660293 4660293 intron 1 0.23 4E-10 .48 1 40075259 40075741 1 40028180 40028180 -1.07284814845 7.31957967878E-9 0.580656373403 -0.705709363431 0.153870397324 3.950006E-6 03/28/2011 21300955 Dehghan A 02/07/2011 Circulation C-reactive protein 1p34.3 1 40064961 PABPC4 SNORA55 - HEYL rs12037222-A rs12037222 12037222 Intergenic 2 NR 6E-11 .05 1 40075259 40075741 1 40064961 40064961 -1.07848583938 5.15726187261E-9 0.562604795098 -0.710646213171 0.152530834523 2.905096E-6 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72796185 72798979 1 72765116 72765116 -1.20867225434 5.16696249359E-23 1.71269607774 -0.930492585722 0.0679746893002 7.649974E-18 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72796185 72798979 1 72765116 72765116 -1.20867225434 5.16696249359E-23 1.71269607774 -0.930492585722 0.0679746893002 7.649974E-18 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72799694 72800537 1 72765116 72765116 -1.18010751528 5.92472572085E-18 1.66568505491 -0.885740629038 0.0883494526559 7.133425E-14 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72799694 72800537 1 72765116 72765116 -1.18010751528 5.92472572085E-18 1.66568505491 -0.885740629038 0.0883494526559 7.133425E-14 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72801743 72802276 1 72765116 72765116 -1.11681680055 1.74006473042E-17 1.5797661938 -0.88028639765 0.0859891506592 1.649021E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72801743 72802276 1 72765116 72765116 -1.11681680055 1.74006473042E-17 1.5797661938 -0.88028639765 0.0859891506592 1.649021E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72802291 72802819 1 72765116 72765116 -1.16675191258 3.76613283367E-17 1.64579146143 -0.87620719749 0.0916772888301 3.24852E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72802291 72802819 1 72765116 72765116 -1.16675191258 3.76613283367E-17 1.64579146143 -0.87620719749 0.0916772888301 3.24852E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72803038 72803427 1 72765116 72765116 -1.1742122668 3.04461429089E-17 1.6618914183 -0.877345368126 0.0917470375068 2.72443E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72803038 72803427 1 72765116 72765116 -1.1742122668 3.04461429089E-17 1.6618914183 -0.877345368126 0.0917470375068 2.72443E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72803485 72803994 1 72765116 72765116 -1.10211926926 5.35220648746E-17 1.56221763414 -0.874301481065 0.0874085963043 4.480357E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72803485 72803994 1 72765116 72765116 -1.10211926926 5.35220648746E-17 1.56221763414 -0.874301481065 0.0874085963043 4.480357E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72804961 72805455 1 72765116 72765116 -1.08816261564 2.88751968615E-16 1.54454356407 -0.864715289209 0.0902928264772 1.698889E-12 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72804961 72805455 1 72765116 72765116 -1.08816261564 2.88751968615E-16 1.54454356407 -0.864715289209 0.0902928264772 1.698889E-12 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72806225 72806815 1 72765116 72765116 -1.15996449077 1.75385114901E-16 1.63418249268 -0.867630190978 0.0949624504793 1.119364E-12 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72806225 72806815 1 72765116 72765116 -1.15996449077 1.75385114901E-16 1.63418249268 -0.867630190978 0.0949624504793 1.119364E-12 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72806841 72807424 1 72765116 72765116 -1.25686619901 2.78624624967E-18 1.77487545407 -0.889402458378 0.0922842646838 3.960399E-14 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72806841 72807424 1 72765116 72765116 -1.25686619901 2.78624624967E-18 1.77487545407 -0.889402458378 0.0922842646838 3.960399E-14 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72807431 72807754 1 72765116 72765116 -1.06054008558 2.98232369049E-14 1.50394087378 -0.834020131889 0.100226432288 8.611329E-11 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72807431 72807754 1 72765116 72765116 -1.06054008558 2.98232369049E-14 1.50394087378 -0.834020131889 0.100226432288 8.611329E-11 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72808237 72809474 1 72765116 72765116 -1.24501436591 5.46941957942E-20 1.75345137491 -0.906575190751 0.0828000447067 1.933577E-15 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72808237 72809474 1 72765116 72765116 -1.24501436591 5.46941957942E-20 1.75345137491 -0.906575190751 0.0828000447067 1.933577E-15 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72809576 72809943 1 72765116 72765116 -1.06848541978 2.80712523398E-14 1.51515474663 -0.834466658626 0.100799696277 8.177078E-11 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72809576 72809943 1 72765116 72765116 -1.06848541978 2.80712523398E-14 1.51515474663 -0.834466658626 0.100799696277 8.177078E-11 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72766881 72767328 1 72765116 72765116 -1.02123935143 8.80473143706E-12 1.45059109958 -0.785448123344 0.114961327899 1.113983E-8 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72766881 72767328 1 72765116 72765116 -1.02123935143 8.80473143706E-12 1.45059109958 -0.785448123344 0.114961327899 1.113983E-8 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72767357 72768295 1 72765116 72765116 -1.210268924 2.77777071414E-15 1.70672414103 -0.850581109091 0.106887009256 1.150795E-11 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72767357 72768295 1 72765116 72765116 -1.210268924 2.77777071414E-15 1.70672414103 -0.850581109091 0.106887009256 1.150795E-11 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72769053 72770092 1 72765116 72765116 -1.2444924079 1.0198566841E-20 1.76189585753 -0.913035577316 0.0794216386754 6.098208E-16 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72769053 72770092 1 72765116 72765116 -1.2444924079 1.0198566841E-20 1.76189585753 -0.913035577316 0.0794216386754 6.098208E-16 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72771067 72771577 1 72765116 72765116 -1.13821260876 6.54835273864E-17 1.61478815439 -0.873193632925 0.0907562742173 5.345899E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72771067 72771577 1 72765116 72765116 -1.13821260876 6.54835273864E-17 1.61478815439 -0.873193632925 0.0907562742173 5.345899E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72771646 72772131 1 72765116 72765116 -1.16177202431 5.19403925041E-14 1.6470126145 -0.829865944115 0.111588694541 1.391689E-10 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72771646 72772131 1 72765116 72765116 -1.16177202431 5.19403925041E-14 1.6470126145 -0.829865944115 0.111588694541 1.391689E-10 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72772215 72773342 1 72765116 72765116 -1.21485602222 4.10861560054E-18 1.71748864243 -0.887533128575 0.0900952296488 5.171434E-14 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72772215 72773342 1 72765116 72765116 -1.21485602222 4.10861560054E-18 1.71748864243 -0.887533128575 0.0900952296488 5.171434E-14 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72773415 72773823 1 72765116 72765116 -0.997224833774 7.53935335392E-13 1.41286906176 -0.808153855684 0.10382339459 1.30859E-9 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72773415 72773823 1 72765116 72765116 -0.997224833774 7.53935335392E-13 1.41286906176 -0.808153855684 0.10382339459 1.30859E-9 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72774028 72774585 1 72765116 72765116 -1.12128811272 1.35990849421E-14 1.58796593204 -0.839710987754 0.103589567396 4.372866E-11 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72774028 72774585 1 72765116 72765116 -1.12128811272 1.35990849421E-14 1.58796593204 -0.839710987754 0.103589567396 4.372866E-11 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72775035 72775967 1 72765116 72765116 -1.04795299001 2.52065232857E-16 1.49239320421 -0.865516473262 0.0866368217593 1.50925E-12 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72775035 72775967 1 72765116 72765116 -1.04795299001 2.52065232857E-16 1.49239320421 -0.865516473262 0.0866368217593 1.50925E-12 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72775983 72778166 1 72765116 72765116 -1.15569662589 9.66486605493E-21 1.64073091504 -0.913234441031 0.0736582341632 6.098208E-16 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72775983 72778166 1 72765116 72765116 -1.15569662589 9.66486605493E-21 1.64073091504 -0.913234441031 0.0736582341632 6.098208E-16 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72778844 72779744 1 72765116 72765116 -1.22589939055 7.93262644189E-17 1.72804880794 -0.872130651281 0.0982486388782 6.286627E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72778844 72779744 1 72765116 72765116 -1.22589939055 7.93262644189E-17 1.72804880794 -0.872130651281 0.0982486388782 6.286627E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72780588 72780945 1 72765116 72765116 -0.907963636866 4.10061982244E-10 1.29351853237 -0.743536988609 0.116652966899 3.232319E-7 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72780588 72780945 1 72765116 72765116 -0.907963636866 4.10061982244E-10 1.29351853237 -0.743536988609 0.116652966899 3.232319E-7 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72784780 72785221 1 72765116 72765116 -1.25676782256 5.31131019827E-20 1.76855562299 -0.906692241472 0.0835211165108 1.933577E-15 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72784780 72785221 1 72765116 72765116 -1.25676782256 5.31131019827E-20 1.76855562299 -0.906692241472 0.0835211165108 1.933577E-15 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72785635 72786540 1 72765116 72765116 -1.15499628779 2.73598703991E-19 1.63540744931 -0.899908678447 0.0799555625713 6.056221E-15 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72785635 72786540 1 72765116 72765116 -1.15499628779 2.73598703991E-19 1.63540744931 -0.899908678447 0.0799555625713 6.056221E-15 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72786891 72787412 1 72765116 72765116 -1.05479069847 4.91448172064E-13 1.50070148989 -0.811824966521 0.10837895744 9.000006E-10 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72786891 72787412 1 72765116 72765116 -1.05479069847 4.91448172064E-13 1.50070148989 -0.811824966521 0.10837895744 9.000006E-10 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72788206 72789148 1 72765116 72765116 -1.02470748505 1.11342363709E-17 1.45890095689 -0.882579610864 0.0779823666633 1.161677E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72788206 72789148 1 72765116 72765116 -1.02470748505 1.11342363709E-17 1.45890095689 -0.882579610864 0.0779823666633 1.161677E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72789174 72790089 1 72765116 72765116 -1.12525380164 8.6957612036E-17 1.59121970899 -0.871618143836 0.0904037894969 6.733895E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72789174 72790089 1 72765116 72765116 -1.12525380164 8.6957612036E-17 1.59121970899 -0.871618143836 0.0904037894969 6.733895E-13 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72790223 72790888 1 72765116 72765116 -0.722251166952 3.17039009931E-10 1.04379876063 -0.746624722341 0.0919326472993 2.594473E-7 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72790223 72790888 1 72765116 72765116 -0.722251166952 3.17039009931E-10 1.04379876063 -0.746624722341 0.0919326472993 2.594473E-7 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72791123 72792402 1 72765116 72765116 -1.27414962019 1.60382431436E-20 1.79923192814 -0.911341540778 0.0822186727093 8.219003E-16 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72791123 72792402 1 72765116 72765116 -1.27414962019 1.60382431436E-20 1.79923192814 -0.911341540778 0.0822186727093 8.219003E-16 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72792903 72794676 1 72765116 72765116 -1.168599068 2.39864391376E-18 1.65400761514 -0.890114582006 0.0854743247239 3.960399E-14 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72792903 72794676 1 72765116 72765116 -1.168599068 2.39864391376E-18 1.65400761514 -0.890114582006 0.0854743247239 3.960399E-14 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 1E-11 3.77 1 72794697 72796141 1 72765116 72765116 -1.18065844588 2.12599751521E-19 1.66807993833 -0.900985437516 0.0812170849993 5.005893E-15 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 1p31.1 1 72765116 NEGR1 NEGR1 - RPL31P12 rs2568958-A rs2568958 2568958 Intergenic 2 0.58 2E-8 3.37 1 72794697 72796141 1 72765116 72765116 -1.18065844588 2.12599751521E-19 1.66807993833 -0.900985437516 0.0812170849993 5.005893E-15 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72796185 72798979 1 72812440 72812440 -1.20867225434 5.16696249359E-23 1.71269607774 -0.930492585722 0.0679746893002 7.649974E-18 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72796185 72798979 1 72812440 72812440 -1.20867225434 5.16696249359E-23 1.71269607774 -0.930492585722 0.0679746893002 7.649974E-18 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72799694 72800537 1 72812440 72812440 -1.18010751528 5.92472572085E-18 1.66568505491 -0.885740629038 0.0883494526559 7.133425E-14 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72799694 72800537 1 72812440 72812440 -1.18010751528 5.92472572085E-18 1.66568505491 -0.885740629038 0.0883494526559 7.133425E-14 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72801743 72802276 1 72812440 72812440 -1.11681680055 1.74006473042E-17 1.5797661938 -0.88028639765 0.0859891506592 1.649021E-13 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72801743 72802276 1 72812440 72812440 -1.11681680055 1.74006473042E-17 1.5797661938 -0.88028639765 0.0859891506592 1.649021E-13 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72802291 72802819 1 72812440 72812440 -1.16675191258 3.76613283367E-17 1.64579146143 -0.87620719749 0.0916772888301 3.24852E-13 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72802291 72802819 1 72812440 72812440 -1.16675191258 3.76613283367E-17 1.64579146143 -0.87620719749 0.0916772888301 3.24852E-13 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72803038 72803427 1 72812440 72812440 -1.1742122668 3.04461429089E-17 1.6618914183 -0.877345368126 0.0917470375068 2.72443E-13 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72803038 72803427 1 72812440 72812440 -1.1742122668 3.04461429089E-17 1.6618914183 -0.877345368126 0.0917470375068 2.72443E-13 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72803485 72803994 1 72812440 72812440 -1.10211926926 5.35220648746E-17 1.56221763414 -0.874301481065 0.0874085963043 4.480357E-13 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72803485 72803994 1 72812440 72812440 -1.10211926926 5.35220648746E-17 1.56221763414 -0.874301481065 0.0874085963043 4.480357E-13 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72804961 72805455 1 72812440 72812440 -1.08816261564 2.88751968615E-16 1.54454356407 -0.864715289209 0.0902928264772 1.698889E-12 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72804961 72805455 1 72812440 72812440 -1.08816261564 2.88751968615E-16 1.54454356407 -0.864715289209 0.0902928264772 1.698889E-12 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72806225 72806815 1 72812440 72812440 -1.15996449077 1.75385114901E-16 1.63418249268 -0.867630190978 0.0949624504793 1.119364E-12 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72806225 72806815 1 72812440 72812440 -1.15996449077 1.75385114901E-16 1.63418249268 -0.867630190978 0.0949624504793 1.119364E-12 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72806841 72807424 1 72812440 72812440 -1.25686619901 2.78624624967E-18 1.77487545407 -0.889402458378 0.0922842646838 3.960399E-14 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72806841 72807424 1 72812440 72812440 -1.25686619901 2.78624624967E-18 1.77487545407 -0.889402458378 0.0922842646838 3.960399E-14 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72807431 72807754 1 72812440 72812440 -1.06054008558 2.98232369049E-14 1.50394087378 -0.834020131889 0.100226432288 8.611329E-11 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72807431 72807754 1 72812440 72812440 -1.06054008558 2.98232369049E-14 1.50394087378 -0.834020131889 0.100226432288 8.611329E-11 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72808237 72809474 1 72812440 72812440 -1.24501436591 5.46941957942E-20 1.75345137491 -0.906575190751 0.0828000447067 1.933577E-15 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72808237 72809474 1 72812440 72812440 -1.24501436591 5.46941957942E-20 1.75345137491 -0.906575190751 0.0828000447067 1.933577E-15 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72809576 72809943 1 72812440 72812440 -1.06848541978 2.80712523398E-14 1.51515474663 -0.834466658626 0.100799696277 8.177078E-11 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72809576 72809943 1 72812440 72812440 -1.06848541978 2.80712523398E-14 1.51515474663 -0.834466658626 0.100799696277 8.177078E-11 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72766881 72767328 1 72812440 72812440 -1.02123935143 8.80473143706E-12 1.45059109958 -0.785448123344 0.114961327899 1.113983E-8 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72766881 72767328 1 72812440 72812440 -1.02123935143 8.80473143706E-12 1.45059109958 -0.785448123344 0.114961327899 1.113983E-8 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72767357 72768295 1 72812440 72812440 -1.210268924 2.77777071414E-15 1.70672414103 -0.850581109091 0.106887009256 1.150795E-11 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72767357 72768295 1 72812440 72812440 -1.210268924 2.77777071414E-15 1.70672414103 -0.850581109091 0.106887009256 1.150795E-11 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72769053 72770092 1 72812440 72812440 -1.2444924079 1.0198566841E-20 1.76189585753 -0.913035577316 0.0794216386754 6.098208E-16 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72769053 72770092 1 72812440 72812440 -1.2444924079 1.0198566841E-20 1.76189585753 -0.913035577316 0.0794216386754 6.098208E-16 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72771067 72771577 1 72812440 72812440 -1.13821260876 6.54835273864E-17 1.61478815439 -0.873193632925 0.0907562742173 5.345899E-13 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72771067 72771577 1 72812440 72812440 -1.13821260876 6.54835273864E-17 1.61478815439 -0.873193632925 0.0907562742173 5.345899E-13 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72771646 72772131 1 72812440 72812440 -1.16177202431 5.19403925041E-14 1.6470126145 -0.829865944115 0.111588694541 1.391689E-10 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72771646 72772131 1 72812440 72812440 -1.16177202431 5.19403925041E-14 1.6470126145 -0.829865944115 0.111588694541 1.391689E-10 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72772215 72773342 1 72812440 72812440 -1.21485602222 4.10861560054E-18 1.71748864243 -0.887533128575 0.0900952296488 5.171434E-14 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72772215 72773342 1 72812440 72812440 -1.21485602222 4.10861560054E-18 1.71748864243 -0.887533128575 0.0900952296488 5.171434E-14 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72773415 72773823 1 72812440 72812440 -0.997224833774 7.53935335392E-13 1.41286906176 -0.808153855684 0.10382339459 1.30859E-9 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72773415 72773823 1 72812440 72812440 -0.997224833774 7.53935335392E-13 1.41286906176 -0.808153855684 0.10382339459 1.30859E-9 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72774028 72774585 1 72812440 72812440 -1.12128811272 1.35990849421E-14 1.58796593204 -0.839710987754 0.103589567396 4.372866E-11 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72774028 72774585 1 72812440 72812440 -1.12128811272 1.35990849421E-14 1.58796593204 -0.839710987754 0.103589567396 4.372866E-11 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72775035 72775967 1 72812440 72812440 -1.04795299001 2.52065232857E-16 1.49239320421 -0.865516473262 0.0866368217593 1.50925E-12 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72775035 72775967 1 72812440 72812440 -1.04795299001 2.52065232857E-16 1.49239320421 -0.865516473262 0.0866368217593 1.50925E-12 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72775983 72778166 1 72812440 72812440 -1.15569662589 9.66486605493E-21 1.64073091504 -0.913234441031 0.0736582341632 6.098208E-16 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72775983 72778166 1 72812440 72812440 -1.15569662589 9.66486605493E-21 1.64073091504 -0.913234441031 0.0736582341632 6.098208E-16 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72778844 72779744 1 72812440 72812440 -1.22589939055 7.93262644189E-17 1.72804880794 -0.872130651281 0.0982486388782 6.286627E-13 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72778844 72779744 1 72812440 72812440 -1.22589939055 7.93262644189E-17 1.72804880794 -0.872130651281 0.0982486388782 6.286627E-13 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72780588 72780945 1 72812440 72812440 -0.907963636866 4.10061982244E-10 1.29351853237 -0.743536988609 0.116652966899 3.232319E-7 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72780588 72780945 1 72812440 72812440 -0.907963636866 4.10061982244E-10 1.29351853237 -0.743536988609 0.116652966899 3.232319E-7 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72784780 72785221 1 72812440 72812440 -1.25676782256 5.31131019827E-20 1.76855562299 -0.906692241472 0.0835211165108 1.933577E-15 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72784780 72785221 1 72812440 72812440 -1.25676782256 5.31131019827E-20 1.76855562299 -0.906692241472 0.0835211165108 1.933577E-15 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72785635 72786540 1 72812440 72812440 -1.15499628779 2.73598703991E-19 1.63540744931 -0.899908678447 0.0799555625713 6.056221E-15 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72785635 72786540 1 72812440 72812440 -1.15499628779 2.73598703991E-19 1.63540744931 -0.899908678447 0.0799555625713 6.056221E-15 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72786891 72787412 1 72812440 72812440 -1.05479069847 4.91448172064E-13 1.50070148989 -0.811824966521 0.10837895744 9.000006E-10 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72786891 72787412 1 72812440 72812440 -1.05479069847 4.91448172064E-13 1.50070148989 -0.811824966521 0.10837895744 9.000006E-10 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72788206 72789148 1 72812440 72812440 -1.02470748505 1.11342363709E-17 1.45890095689 -0.882579610864 0.0779823666633 1.161677E-13 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72788206 72789148 1 72812440 72812440 -1.02470748505 1.11342363709E-17 1.45890095689 -0.882579610864 0.0779823666633 1.161677E-13 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72789174 72790089 1 72812440 72812440 -1.12525380164 8.6957612036E-17 1.59121970899 -0.871618143836 0.0904037894969 6.733895E-13 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72789174 72790089 1 72812440 72812440 -1.12525380164 8.6957612036E-17 1.59121970899 -0.871618143836 0.0904037894969 6.733895E-13 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72790223 72790888 1 72812440 72812440 -0.722251166952 3.17039009931E-10 1.04379876063 -0.746624722341 0.0919326472993 2.594473E-7 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72790223 72790888 1 72812440 72812440 -0.722251166952 3.17039009931E-10 1.04379876063 -0.746624722341 0.0919326472993 2.594473E-7 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72791123 72792402 1 72812440 72812440 -1.27414962019 1.60382431436E-20 1.79923192814 -0.911341540778 0.0822186727093 8.219003E-16 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72791123 72792402 1 72812440 72812440 -1.27414962019 1.60382431436E-20 1.79923192814 -0.911341540778 0.0822186727093 8.219003E-16 01/12/2009 19079261 Willer CJ 12/14/2008 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.62 6E-8 .10 1 72792903 72794676 1 72812440 72812440 -1.168599068 2.39864391376E-18 1.65400761514 -0.890114582006 0.0854743247239 3.960399E-14 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 1p31.1 1 72812440 NEGR1 RPL31P12 - KRT8P21 rs2815752-A rs2815752 2815752 Intergenic 2 0.61 2E-22 .13 1 72792903 72794676 1 72812440 72812440 -1.168599068 2.39864391376E-18 1.65400761514 -0.890114582006 0.0854743247239 3.960399E-14 01/12/2009 19079261 Willer CJ 12/14/2008 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Chen W 04/12/2010 Proc Natl Acad Sci U S A Age-related macular degeneration 1q31.3 1 196646176 CFH CFH rs1329424-T rs1329424 1329424 intron 1 0.351 6E-16 1.88 1 196692371 196692905 1 196646176 196646176 1.18476696351 5.75865634158E-8 -1.43008886152 0.674437810455 0.185286798461 2.390371E-5 05/06/2010 20385826 Neale BM 04/12/2010 Proc Natl Acad Sci U S A Age-related macular degeneration 1q31.3 1 196659237 CFH CFH rs1061170-? rs1061170 1061170 missense 1 NR 4E-117 NR 1 196692371 196692905 1 196659237 196659237 1.18476696351 5.75865634158E-8 -1.43008886152 0.674437810455 0.185286798461 2.390371E-5 06/29/2011 21665990 Yu Y 06/10/2011 Hum Mol Genet Age-related macular degeneration 1q31.3 1 196659237 CFH CFH rs1061170-C rs1061170 1061170 missense 1 0.37 1E-261 2.41 1 196692371 196692905 1 196659237 196659237 1.18476696351 5.75865634158E-8 -1.43008886152 0.674437810455 0.185286798461 2.390371E-5 05/06/2010 20385819 Chen W 04/12/2010 Proc Natl Acad Sci U S A Age-related macular degeneration 1q31.3 1 196679455 CFH CFH rs10737680-A rs10737680 10737680 intron 1 0.566 2E-76 3.11 1 196692371 196692905 1 196679455 196679455 1.08773788156 6.81463242579E-8 -0.842911675721 0.671707516655 0.17137861252 2.75536E-5 05/06/2010 20385819 Chen W 04/12/2010 Proc Natl Acad Sci U S A Age-related macular degeneration 1q31.3 1 196679455 CFH CFH rs10737680-A rs10737680 10737680 intron 1 0.566 2E-76 3.11 1 196712312 196712773 1 196679455 196679455 0.686857518549 1.51352616593E-4 -0.558500658925 0.506097169411 0.167217590763 0.01812406 04/12/2011 21399633 Gharavi AG 03/13/2011 Nat Genet Nephropathy 1q31.3 1 196686918 CFH, CFHR3, CFHR1, CFHR4, CHFR2, CFHR5 CFH rs6677604-? rs6677604 6677604 intron 1 0.77 (EA) 3E-10 1.47 1 196692371 196692905 1 196686918 196686918 0.853878206308 5.78630008878E-4 -0.408351673668 0.465419775886 0.231974648216 0.05098193 05/06/2010 20385826 Neale BM 04/12/2010 Proc Natl Acad Sci U S A Age-related macular degeneration 1q31.3 1 196696933 CFH CFH rs1410996-? rs1410996 1410996 intron 1 NR 2E-111 NR 1 196692371 196692905 1 196696933 196696933 1.08773788156 6.81463242579E-8 -0.842911675721 0.671707516655 0.17137861252 2.75536E-5 05/06/2010 20385826 Neale BM 04/12/2010 Proc Natl Acad Sci U S A Age-related macular degeneration 1q31.3 1 196696933 CFH CFH rs1410996-? rs1410996 1410996 intron 1 NR 2E-111 NR 1 196712312 196712773 1 196696933 196696933 0.686857518549 1.51352616593E-4 -0.558500658925 0.506097169411 0.167217590763 0.01812406 11/25/2008 15761122 Klein RJ 03/10/2005 Science Age-related macular degeneration 1q31.3 1 196701051 CFH CFH rs380390-C rs380390 380390 intron 1 0.70 (HapMap CEU) 4E-8 4.60 1 196692371 196692905 1 196701051 196701051 1.51107813194 2.13425168318E-19 -1.58974900635 0.900968989356 0.103956622042 5.005893E-15 11/25/2008 15761122 Klein RJ 03/10/2005 Science Age-related macular degeneration 1q31.3 1 196701051 CFH CFH rs380390-C rs380390 380390 intron 1 0.70 (HapMap CEU) 4E-8 4.60 1 196712312 196712773 1 196701051 196701051 0.925361123839 1.51669704282E-7 -0.999583010795 0.658332764026 0.151148989519 5.569006E-5 10/14/2010 20861866 Kopplin LJ 09/23/2010 Genes Immun Age-related macular degeneration 1q31.3 1 196702810 CFH CFH rs1329428-? rs1329428 1329428 intron 1 NR 3E-64 2.78 1 196692371 196692905 1 196702810 196702810 1.08773788156 6.81463242579E-8 -0.842911675721 0.671707516655 0.17137861252 2.75536E-5 10/14/2010 20861866 Kopplin LJ 09/23/2010 Genes Immun Age-related macular degeneration 1q31.3 1 196702810 CFH CFH rs1329428-? rs1329428 1329428 intron 1 NR 3E-64 2.78 1 196712312 196712773 1 196702810 196702810 0.686857518549 1.51352616593E-4 -0.558500658925 0.506097169411 0.167217590763 0.01812406 09/11/2009 19684603 Trevino LR 08/16/2009 Nat Genet Acute lymphoblastic leukemia (childhood) 1q31.3 1 196844593 Intergenic CFHR1 - CFHR4 rs6428370-G rs6428370 6428370 Intergenic 2 0.32 7E-6 1.43 1 196796906 196797336 1 196844593 196844593 -0.913557828072 2.46585332986E-8 0.667638545375 -0.687769434861 0.137749299264 1.142756E-5 11/25/2008 17903295 Lunetta KL 09/19/2007 BMC Med Genet Aging traits 1q42.3 1 235720898 GNG4 GNG4 rs291353-? rs291353 291353 intron 1 NR 6E-6 NR 1 235746897 235747407 1 235720898 235720898 0.441904157649 0.00122374225439 -0.417662821771 0.440295642515 0.128733277879 0.08764453 01/06/2011 21076409 Sotoodehnia N 11/14/2010 Nat Genet Ventricular conduction 2p22.2 2 37248015 HEATR5B, STRN HEATR5B rs17020136-C rs17020136 17020136 intron 1 0.21 2E-9 .51 2 37232137 37232562 2 37248015 37248015 -1.02990530549 1.45636543598E-7 0.4533546038 -0.659027759924 0.167912058051 5.389831E-5 01/18/2011 20953190 Strange A 10/17/2010 Nat Genet Psoriasis 2p16.1 2 61081542 REL RPL21P33 - REL rs702873-G rs702873 702873 Intergenic 2 0.56 4E-9 1.12 2 61066413 61066838 2 61081542 61081542 0.532135225456 4.39545452009E-4 -0.407686082113 0.474181253968 0.141147458457 0.04138528 01/27/2012 22170493 Ellinghaus E 12/15/2011 J Invest Dermatol Psoriatic arthritis 2p16.1 2 61081542 REL RPL21P33 - REL rs702873-? rs702873 702873 Intergenic 2 NR 2E-7 1.20 2 61066413 61066838 2 61081542 61081542 0.532135225456 4.39545452009E-4 -0.407686082113 0.474181253968 0.141147458457 0.04138528 02/24/2012 21886157 Suhre K 08/31/2011 Nature Metabolic traits 2p13.1 2 73818936 NAT8 ALMS1 rs13391552-A rs13391552 13391552 intron 1 0.216 5E-252 .37 2 73851788 73852183 2 73818936 73818936 -0.5231543639 2.45787045558E-4 0.209551389165 -0.491968840908 0.132257182434 0.026465 05/05/2010 20383146 Kottgen A 04/11/2010 Nat Genet Chronic kidney disease 2p13.1 2 73868328 NAT8,NAT8B,ALMS1 NAT8 rs13538-G rs13538 13538 missense 1 0.23 5E-14 .01 2 73851788 73852183 2 73868328 73868328 -0.709294627258 9.28985646589E-7 0.341136832564 -0.62535521629 0.126440394782 2.640142E-4 05/05/2010 20383146 Kottgen A 04/11/2010 Nat Genet Chronic kidney disease 2p13.1 2 73868328 NAT8,NAT8B,ALMS1 NAT8 rs13538-G rs13538 13538 missense 1 0.23 5E-14 .01 2 73906857 73907723 2 73868328 73868328 -0.619732547573 1.20136873047E-4 0.239193756677 -0.51261687516 0.148290415169 0.01514312 05/05/2010 20383146 Kottgen A 04/11/2010 Nat Genet Chronic kidney disease 2p13.1 2 73868328 NAT8,NAT8B,ALMS1 NAT8 rs13538-G rs13538 13538 missense 1 0.23 5E-14 .01 2 73917784 73918160 2 73868328 73868328 0.875073982092 1.53643534327E-5 -0.390810986111 0.565437256561 0.182350260718 0.002835165 05/05/2010 20383145 Chambers JC 04/11/2010 Nat Genet Creatinine levels 2p13.1 2 73900900 NAT8,NAT8B,ALMS1,DUSP11,TPRKB ALMS1P rs10206899-G rs10206899 10206899 1 0.22 1E-15 1.00 2 73851788 73852183 2 73900900 73900900 -0.709294627258 9.28985646589E-7 0.341136832564 -0.62535521629 0.126440394782 2.640142E-4 05/05/2010 20383145 Chambers JC 04/11/2010 Nat Genet Creatinine levels 2p13.1 2 73900900 NAT8,NAT8B,ALMS1,DUSP11,TPRKB ALMS1P rs10206899-G rs10206899 10206899 1 0.22 1E-15 1.00 2 73906857 73907723 2 73900900 73900900 -0.619732547573 1.20136873047E-4 0.239193756677 -0.51261687516 0.148290415169 0.01514312 05/05/2010 20383145 Chambers JC 04/11/2010 Nat Genet Creatinine levels 2p13.1 2 73900900 NAT8,NAT8B,ALMS1,DUSP11,TPRKB ALMS1P rs10206899-G rs10206899 10206899 1 0.22 1E-15 1.00 2 73917784 73918160 2 73900900 73900900 0.875073982092 1.53643534327E-5 -0.390810986111 0.565437256561 0.182350260718 0.002835165 04/06/2010 20195266 Adkins DE 03/02/2010 Mol Psychiatry Response to antipsychotic treatment 2p11.2 2 84350917 Intergenic RPL37P10 - FUNDC2P2 rs1534238-? rs1534238 1534238 Intergenic 2 0.381 3E-6 NR 2 84304595 84305101 2 84350917 84350917 0.608602994462 0.00122490040204 -0.712803235546 0.440262672829 0.17731160722 0.08770584 04/20/2012 22451204 Pankratz N 03/01/2012 Ann Neurol Parkinson's disease 2q21.3 2 135539967 Intergenic TMEM163 - ACMSD rs6430538-? rs6430538 6430538 Intergenic 2 NR 2E-7 1.15 2 135540345 135540786 2 135539967 135539967 1.30075946254 5.17845029438E-15 -0.976224096147 0.846417293781 0.116909691155 1.906992E-11 01/06/2011 21079607 Wang K 11/16/2010 Mol Psychiatry Anorexia nervosa 3p25.3 3 11675789 VGLL4 VGLL4 rs6782029-? rs6782029 6782029 intron 1 0.24 9E-6 NR 3 11661145 11661665 3 11675789 11675789 0.646808428878 1.178466873E-4 -0.384686124314 0.513154243146 0.154549285304 0.01491548 11/25/2008 18759275 McArdle PF 09/01/2008 Arthritis Rheum Uric acid levels 3p25.1 3 15440556 NR HMGN2L7 - METTL6 rs6442522-? rs6442522 6442522 Intergenic 2 NR 5E-6 .05 3 15440342 15440715 3 15440556 15440556 -1.46666165035 3.15076758607E-17 1.19447404196 -0.877162713072 0.114701157768 2.794814E-13 06/01/2011 21502085 Troyer JL 05/01/2011 J Infect Dis AIDS progression 3p21.31 3 46428190 CCRL2 CCR5 - CCRL2 rs6441975-? rs6441975 6441975 Intergenic 2 0.31 5E-6 1.48 3 46413996 46414402 3 46428190 46428190 -0.461842061937 4.43248060369E-4 0.596862533959 -0.473917351268 0.122590379271 0.0416837 06/01/2011 21502085 Troyer JL 05/01/2011 J Infect Dis AIDS progression 3p21.31 3 46451680 LTF CCRL2 - LTF rs1015164-? rs1015164 1015164 Intergenic 2 0.31 9E-6 1.46 3 46413996 46414402 3 46451680 46451680 -0.461842061937 4.43248060369E-4 0.596862533959 -0.473917351268 0.122590379271 0.0416837 06/15/2009 19483685 Daly AK 05/31/2009 Nat Genet Drug-induced liver injury (flucloxacillin) 3q11.2 3 98034526 OR5H2 OR5H8P - OR5K4 rs1497546-? rs1497546 1497546 Intergenic 2 0.02 2E-7 6.57 3 98052833 98053223 3 98034526 98034526 1.72222436809 4.20977515104E-5 -0.194449914246 0.54065280287 0.382821354522 0.006488526 07/21/2012 22566498 Turner ST 05/07/2012 Hypertension Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy) 3q21.1 3 122380923 EIF4BP8 LHFPL3 rs790116-G rs790116 790116 intron 1 NR 2E-7 NR 3 122379411 122379884 3 122380923 122380923 -0.642898194669 1.80453250811E-4 0.562939836031 -0.501043576884 0.158634128204 0.02078285 07/21/2012 22566498 Turner ST 05/07/2012 Hypertension Response to angiotensin II receptor blocker therapy 3q21.1 3 122388993 EIF4BP8 EIF4BP8 - PARP14 rs790123-T rs790123 790123 Intergenic 2 NR 6E-6 1.07 3 122379411 122379884 3 122388993 122388993 -0.642898194669 1.80453250811E-4 0.562939836031 -0.501043576884 0.158634128204 0.02078285 01/31/2012 22139419 Gieger C 11/30/2011 Nature Mean platelet volume 3q21.2 3 124340222 KALRN KALRN rs10512627-C rs10512627 10512627 intron 1 NR 5E-10 .01 3 124339333 124339696 3 124340222 124340222 -1.17420784764 3.63810356251E-10 1.26502138909 -0.744978710926 0.150205681868 2.919439E-7 03/27/2012 22359512 Demirkan A 02/16/2012 PLoS Genet Phospholipid levels (plasma) 3q23 3 142649110 PAQR9 RPL8P3 - PAQR9 rs9832727-? rs9832727 9832727 Intergenic 2 NR 6E-29 .00 3 142650043 142650542 3 142649110 142649110 -0.999158983936 5.18037384533E-7 0.857854640691 -0.636415665643 0.172999597121 1.594202E-4 09/02/2011 21782286 Walter S 07/20/2011 Neurobiol Aging Aging (time to death) 3q26.1 3 162681995 OTOL1 TOMM22P6 - RPS6P4 rs1425609-A rs1425609 1425609 Intergenic 2 0.38 1E-6 .08 3 162718066 162718437 3 162681995 162681995 -1.02260615306 2.64777912173E-6 0.803933523717 -0.604381474484 0.19257120456 6.460597E-4 09/02/2011 21782286 Walter S 07/20/2011 Neurobiol Aging Aging (time to death) 3q26.1 3 162681995 OTOL1 TOMM22P6 - RPS6P4 rs1425609-A rs1425609 1425609 Intergenic 2 0.38 1E-6 .08 3 162718554 162719226 3 162681995 162681995 -1.15860986157 2.04305395704E-7 0.927717346982 -0.65317638887 0.191876871216 7.212046E-5 09/02/2011 21782286 Walter S 07/20/2011 Neurobiol Aging Aging (time to death) 3q26.1 3 162681995 OTOL1 TOMM22P6 - RPS6P4 rs1425609-A rs1425609 1425609 Intergenic 2 0.38 1E-6 .08 3 162719719 162720455 3 162681995 162681995 -1.13383483822 2.17040401404E-7 0.91786139031 -0.65211769179 0.188305253605 7.60481E-5 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Body mass index 3q27.2 3 185834290 SFRS10, ETV5, DGKG ETV5 - DGKG rs7647305-C rs7647305 7647305 Intergenic 2 0.77 7E-11 4.42 3 185811261 185811644 3 185834290 185834290 -0.662284328467 0.00132694744584 1.10339085738 -0.437461679148 0.194482539623 0.09264988 01/15/2009 19079260 Thorleifsson G 12/14/2008 Nat Genet Weight 3q27.2 3 185834290 SFRS10, ETV5, DGKG ETV5 - DGKG rs7647305-C rs7647305 7647305 Intergenic 2 0.77 4E-9 4.00 3 185811261 185811644 3 185834290 185834290 -0.662284328467 0.00132694744584 1.10339085738 -0.437461679148 0.194482539623 0.09264988 10/15/2010 20876614 Yoon KA 09/28/2010 Hum Mol Genet Non-small cell lung cancer 3q29 3 194858374 C3orf21 C3orf21 rs2131877-G rs2131877 2131877 intron 1 0.44 2E-8 1.30 3 194838535 194838936 3 194858374 194858374 0.712152916315 7.45397724087E-4 -0.388229326648 0.457137020068 0.197935700913 0.06158727 04/14/2010 20348956 Kiemeney LA 03/28/2010 Nat Genet Urinary bladder cancer 4p16.3 4 1734239 TACC3,TMEM129,SLBP,FGFR3 TACC3 rs798766-T rs798766 798766 intron 1 0.19 1E-11 1.24 4 1731408 1731879 4 1734239 1734239 1.34280531508 2.59577797625E-6 -2.15999466517 0.604793056075 0.252598063626 6.345647E-4 12/08/2010 20972438 Rothman N 10/24/2010 Nat Genet Bladder cancer 4p16.3 4 1734239 TMEM129,TACC3,FGFR3 TACC3 rs798766-T rs798766 798766 intron 1 0.19 4E-13 1.20 4 1731408 1731879 4 1734239 1734239 1.34280531508 2.59577797625E-6 -2.15999466517 0.604793056075 0.252598063626 6.345647E-4 01/31/2012 22139419 Gieger C 11/30/2011 Nature Mean platelet volume 4p16.1 4 6891519 KIAA0232 KIAA0232 - TBC1D14 rs11734132-G rs11734132 11734132 Intergenic 2 NR 1E-11 .01 4 6875014 6875540 4 6891519 6891519 0.727276144585 5.66994328207E-4 -0.32409151327 0.466075210469 0.19722568172 0.05018586 12/09/2008 18957941 Terracciano A 11/24/2008 Mol Psychiatry Personality dimensions 4q12 4 56298194 CLOCK CLOCK rs6832769-A rs6832769 6832769 nearGene-3 1 0.73 2E-6 .14 4 56310973 56311349 4 56298194 56298194 -0.88027166874 8.40048182406E-5 1.22962813584 -0.522461136919 0.205230622091 0.01136307 07/21/2011 20834067 Yashin AI 09/01/2010 Aging (Albany NY) Longevity 4q21.1 4 76889388 SDAD1 SDAD1 rs2273-? rs2273 2273 intron 1 NR 1E-6 NR 4 76862098 76862518 4 76889388 76889388 1.08491051945 5.74328550006E-14 -0.952168039331 0.829101123664 0.104514570058 1.506422E-10 06/01/2011 21507922 Ramsuran V 05/01/2011 Clin Infect Dis Neutrophil count 4q26 4 118651823 AC109592.1, AC092661.1 NT5C3P1 - NDST3 rs4422476-? rs4422476 4422476 Intergenic 2 NR 8E-6 NR 4 118692775 118693237 4 118651823 118651823 0.613386094632 4.47848674946E-5 -0.503727498295 0.539065449594 0.136912331062 0.00682848 04/04/2011 21326311 Bhatnagar P 02/17/2011 J Hum Genet F-cell distribution 4q27 4 120962385 MAD2L1 PDE5A - MAD2L1 rs1845344-T rs1845344 1845344 Intergenic 2 0.27 7E-6 .97 4 120992276 120992741 4 120962385 120962385 -0.517361125196 9.74896939527E-4 0.402125120204 -0.448125320458 0.147441444435 0.07448658 03/02/2011 21244703 Wang JH 01/18/2011 Genome Med Multiple sclerosis 5p13.2 5 35803577 IL7R SPEF2 rs931555-? rs931555 931555 intron 1 NR 4E-7 1.25 5 35815623 35816122 5 35803577 35803577 -0.555877977552 0.00121270551867 0.334383262145 -0.440611240311 0.16179165736 0.08713652 01/16/2011 21302353 Perroud N 12/28/2010 Am J Med Genet B Neuropsychiatr Genet Hoarding 5q11.2 5 57320954 Intergenic ACTBL2 - PLK2 rs1844437-C rs1844437 1844437 Intergenic 2 0.22 2E-6 .62 5 57328529 57329135 5 57320954 57320954 -1.33149290987 2.15297989975E-17 2.22437651934 -0.8791759884 0.103092091991 1.978829E-13 01/16/2011 21302353 Perroud N 12/28/2010 Am J Med Genet B Neuropsychiatr Genet Hoarding 5q11.2 5 57320954 Intergenic ACTBL2 - PLK2 rs1844437-C rs1844437 1844437 Intergenic 2 0.22 2E-6 .62 5 57330933 57331403 5 57320954 57320954 -1.36484613673 1.26656756867E-16 2.27640766511 -0.869496755163 0.110761977809 8.707139E-13 11/25/2008 17903302 Levy D 09/19/2007 BMC Med Genet Tonometry 5q14.3 5 88088439 MEF2C MEF2C rs770189-? rs770189 770189 intron 1 NR 3E-6 NR 5 88116979 88117384 5 88088439 88088439 -0.681833674275 9.76760847591E-4 1.04917269561 -0.448060302334 0.194349343632 0.07458603 04/01/2009 19247474 Caporaso N 02/27/2009 PLoS One Smoking behavior 5q14.3 5 90762748 LOC133789 ARRDC3 - PCBP2P3 rs933688-? rs933688 933688 Intergenic 2 0.17 6E-6 1.48 5 90715424 90715847 5 90762748 90762748 -0.534658665199 0.00119375165959 0.159710133727 -0.441159276246 0.15537572503 0.08614714 09/08/2011 21810271 Antoni G 08/02/2011 BMC Med Genet vWF and FVIII levels 5q22.2 5 111693371 EPB41L4A EPB41L4A rs379440-G rs379440 379440 intron 1 0.04 1E-6 .34 5 111702612 111703180 5 111693371 111693371 -0.864523917089 3.96549705608E-4 0.192802284115 -0.477402593932 0.227314558687 0.03831124 01/06/2009 19023125 Potkin SG 11/20/2008 Schizophr Bull Brain imaging in schizophrenia (interaction) 5q23.2 5 127169212 CTXN3, SLC12A2 CTXN3 - FLJ33630 rs245201-? rs245201 245201 Intergenic 2 0.32 9E-8 NR 5 127169342 127170092 5 127169212 127169212 0.792224039997 2.31674573749E-7 -0.521690670404 0.650970617802 0.131974266397 8.040092E-5 11/25/2008 17554300 WTCCC 06/07/2007 Nature Type 1 diabetes 5q31.1 5 132628884 NR FSTL4 rs17166496-G rs17166496 17166496 intron 1 0.61 5E-6 1.30 5 132623200 132623660 5 132628884 132628884 0.866187384304 1.69136542889E-5 -0.817742806122 0.563158394338 0.181571107688 0.003068549 06/14/2009 19483681 Rapley EA 05/31/2009 Nat Genet Testicular germ cell tumor 5q31.3 5 141681788 SPRY4 NDFIP1 - SPRY4 rs4624820-A rs4624820 4624820 Intergenic 2 0.54 3E-13 1.37 5 141704983 141705369 5 141681788 141681788 -0.554222152001 0.00136378441716 0.435942261637 -0.436497745704 0.163193981613 0.09442727 07/12/2010 20543847 Turnbull C 06/13/2010 Nat Genet Testicular germ cell cancer 5q31.3 5 141681788 SPRY4 NDFIP1 - SPRY4 rs4624820-? rs4624820 4624820 Intergenic 2 0.54 1E-14 1.47 5 141704983 141705369 5 141681788 141681788 -0.554222152001 0.00136378441716 0.435942261637 -0.436497745704 0.163193981613 0.09442727 01/17/2012 22190364 Patsopoulos NA 12/01/2011 Ann Neurol Multiple sclerosis 5q33.3 5 158918894 IL12B IL12B - ADRA1B rs10866713-A rs10866713 10866713 Intergenic 2 0.22 7E-7 1.17 5 158871352 158871864 5 158918894 158918894 -0.578980101506 0.00118148945652 0.229128429957 -0.44151799165 0.168086107292 0.08557668 01/11/2011 21102463 Franke A 11/21/2010 Nat Genet Crohn's disease 5q35.2 5 173279842 CPEB4 BOD1 - CPEB4 rs359457-T rs359457 359457 Intergenic 2 0.57 3E-12 1.08 5 173312648 173313117 5 173279842 173279842 0.792642368676 6.20859774805E-5 -0.927525659346 0.530550971344 0.180913197608 0.008934443 11/17/2010 20935629 Heid IM 10/10/2010 Nat Genet Waist-hip ratio 5q35.2 5 173362458 CPEB4 CPEB4 rs6861681-A rs6861681 6861681 intron 1 0.34 2E-9 .02 5 173312648 173313117 5 173362458 173362458 -0.701730785862 4.70201284432E-4 0.459055871125 -0.472054184528 0.187213521423 0.04353697 09/24/2011 21833088 Sawcer S 08/11/2011 Nature Multiple sclerosis 5q35.3 5 176784512 RGS14 RGS14 rs4075958-A rs4075958 4075958 nearGene-5 1 NR 5E-7 1.09 5 176797734 176798096 5 176784512 176784512 -0.675855373803 1.42309169621E-4 0.482020418539 -0.507849121681 0.163775563171 0.0172829 03/20/2012 22396660 Urabe Y 03/01/2012 PLoS Genet Nephrolithiasis 5q35.3 5 176798306 RGS14, SLC34A1,PFN3, F12 RGS14 rs11746443-? rs11746443 11746443 intron 1 NR 9E-12 1.19 5 176797734 176798096 5 176798306 176798306 -0.657460305719 1.79844409473E-4 0.443613595119 -0.501141443752 0.162185004743 0.02073597 11/08/2011 21998595 N'Diaye A 10/06/2011 PLoS Genet Height 6p25.1 6 5260936 LYRM4 FARS2;LYRM4 rs2224391-A rs2224391 2224391 nearGene-5;missense 1 0.23 3E-6 .05 6 5261260 5261488 6 5260936 5260936 0.553188273857 9.51892786982E-11 -0.202963737584 0.760499952538 0.0674755673803 8.926549E-8 04/03/2012 22412388 Kenny EE 03/08/2012 PLoS Genet Crohn's disease 6p22.1 6 29723161 HLA-F, MOG, HLA-G, GABBR1, HLA-H, UBD, HLA-A IFITM4P - 3.8-1.5 rs9258260-T rs9258260 9258260 Intergenic 2 0.104 2E-10 1.45 6 29673340 29673845 6 29723161 29723161 -1.43502826585 5.44222467929E-10 0.275233393045 -0.740088805623 0.186284525223 4.031511E-7 06/29/2011 21653640 Eleftherohorinou H 06/13/2011 Hum Mol Genet Rheumatoid arthritis 6p22.1 6 29789171 HLA-G HCP5P12 - HLA-G rs1610677-? rs1610677 1610677 Intergenic 2 NR 4E-15 1.32 6 29760119 29760611 6 29789171 29789171 -0.671322499686 6.95021881402E-4 0.605409471508 -0.45944645012 0.185400843981 0.05850142 06/14/2010 20512145 Bei JX 05/30/2010 Nat Genet Nasopharyngeal carcinoma 6p22.1 6 29906691 HLA-A P5.8 - HCG4P5 rs2860580-? rs2860580 2860580 Intergenic 2 0.62 5E-67 1.72 6 29910347 29910838 6 29906691 29906691 -0.705722762077 4.78212167656E-6 0.843253328211 -0.591843650507 0.137306967528 0.001057142 09/04/2009 19664746 Tse KP 08/05/2009 Am J Hum Genet Nasopharyngeal carcinoma 6p22.1 6 29918099 HLA-A HCP5P3 - HCG4P4 rs2517713-A rs2517713 2517713 Intergenic 2 0.62 4E-20 1.88 6 29910347 29910838 6 29918099 29918099 -0.782174621448 5.64157728978E-7 0.993044665244 -0.634827379207 0.135998803357 1.71797E-4 03/08/2012 22319020 Davies RW 02/07/2012 Circ Cardiovasc Genet Coronary heart disease 6p21.33 6 31184196 HCG27, HLA-C HCG27 - HLA-C rs3869109-G rs3869109 3869109 Intergenic 2 NR 1E-9 1.14 6 31164721 31165095 6 31184196 31184196 -0.421884117614 8.00569335744E-5 0.418213026553 -0.523762885151 0.0980236185858 0.01098552 01/13/2011 21051598 Pereyra F 11/04/2010 Science HIV-1 control 6p21.33 6 31274380 HLA-C WASF5P - HLA-B rs9264942-C rs9264942 9264942 Intergenic 2 0.34 3E-35 2.90 6 31312820 31313241 6 31274380 31274380 -0.778302666892 9.98503712808E-6 0.490806497686 -0.575456804685 0.15801631912 0.00196755 01/19/2010 20041166 Fellay J 12/24/2009 PLoS Genet HIV-1 control 6p21.33 6 31274380 HLA-C WASF5P - HLA-B rs9264942-? rs9264942 9264942 Intergenic 2 NR 6E-12 NR 6 31312820 31313241 6 31274380 31274380 -0.778302666892 9.98503712808E-6 0.490806497686 -0.575456804685 0.15801631912 0.00196755 01/19/2010 20041166 Fellay J 12/24/2009 PLoS Genet HIV-1 control 6p21.33 6 31274380 HLA-C WASF5P - HLA-B rs9264942-C rs9264942 9264942 Intergenic 2 0.412 6E-32 5.30 6 31312820 31313241 6 31274380 31274380 -0.778302666892 9.98503712808E-6 0.490806497686 -0.575456804685 0.15801631912 0.00196755 01/13/2011 21051598 Pereyra F 11/04/2010 Science HIV-1 control 6p21.33 6 31322559 HLA-B HLA-B rs2523608-G rs2523608 2523608 intron 1 0.326 9E-20 2.60 6 31341925 31342331 6 31322559 31322559 -0.832988775278 9.80251737288E-6 1.07359854768 -0.575878471571 0.168933891365 0.001937723 05/10/2010 20205591 Pelak K 04/15/2010 J Infect Dis HIV-1 control 6p21.33 6 31322559 HLA-B HLA-B rs2523608-? rs2523608 2523608 intron 1 0.37 3E-6 NR 6 31341925 31342331 6 31322559 31322559 -0.832988775278 9.80251737288E-6 1.07359854768 -0.575878471571 0.168933891365 0.001937723 09/21/2011 21841780 Chu X 08/14/2011 Nat Genet Graves' disease 6p21.33 6 31350704 HLA-B HLA-S - MICA rs1521-T rs1521 1521 Intergenic 2 0.79 2E-65 1.92 6 31341925 31342331 6 31350704 31350704 -0.995084326839 2.44828636257E-6 1.49481694859 -0.606003555491 0.18659760972 6.040906E-4 04/22/2009 19343178 Soranzo N 04/03/2009 PLoS Genet Height 6p21.33 6 31354560 HLA-B HLA-S - MICA rs13437082-? rs13437082 13437082 Intergenic 2 0.13 5E-8 .07 6 31364662 31365066 6 31354560 31354560 -0.52636474424 8.69514942584E-4 0.216570224959 -0.451996165031 0.148398166831 0.06857243 08/18/2011 21801394 Genin E 07/29/2011 Orphanet J Rare Dis Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) 6p21.33 6 31407828 HCP5 MICA - HLA-X rs9469003-C rs9469003 9469003 Intergenic 2 0.15 2E-9 1.73 6 31364662 31365066 6 31407828 31407828 -0.550596868559 0.00104466137898 0.0876253561829 -0.445764453057 0.157952397914 0.07846179 10/18/2011 21946350 Soler Artigas M 09/25/2011 Nat Genet Pulmonary function 6p21.33 6 31472720 MICB MICB rs2855812-T rs2855812 2855812 intron 1 NR 2E-7 .03 6 31464697 31465088 6 31472720 31472720 0.659848388411 1.35146567117E-4 -0.244323044547 0.509310325959 0.159278211363 0.01658664 03/07/2010 20159113 Jakkula E 02/12/2010 Am J Hum Genet Multiple sclerosis 6p21.32 6 32401217 HLA BTNL2 - HLA-DRA rs3135338-A rs3135338 3135338 Intergenic 2 0.13 2E-25 3.43 6 32437629 32438180 6 32401217 32401217 -0.544588727978 0.00117434057269 0.715153364846 -0.441728663847 0.158008138934 0.08523114 08/12/2011 21779181 Gorlova O 07/14/2011 PLoS Genet Systemic sclerosis 6p21.32 6 32409530 HLA-DRA HLA-DRA rs3129882-? rs3129882 3129882 intron 1 0.44 2E-27 2.17 6 32437629 32438180 6 32409530 32409530 -0.583075757344 6.72400499028E-4 0.731416182405 -0.460532911284 0.160547824283 0.05715786 09/22/2010 20711177 Hamza TH 08/15/2010 Nat Genet Parkinson's disease 6p21.32 6 32409530 HLA-DRA HLA-DRA rs3129882-G rs3129882 3129882 intron 1 0.40 2E-10 1.26 6 32437629 32438180 6 32409530 32409530 -0.583075757344 6.72400499028E-4 0.731416182405 -0.460532911284 0.160547824283 0.05715786 06/29/2009 19525953 De Jager PL 06/14/2009 Nat Genet Multiple sclerosis 6p21.32 6 32413051 HLA-DRB1 HLA-DRA rs3135388-A rs3135388 3135388 nearGene-3 1 0.22 4E-225 2.75 6 32437629 32438180 6 32413051 32413051 -0.846617291291 5.54764946813E-6 1.34434073387 -0.58860951497 0.166110665075 0.001201565 11/25/2008 17660530 Hafler DA 07/29/2007 N Engl J Med Multiple sclerosis 6p21.32 6 32413051 HLA-DRA HLA-DRA rs3135388-A rs3135388 3135388 nearGene-3 1 0.23 9E-81 1.99 6 32437629 32438180 6 32413051 32413051 -0.846617291291 5.54764946813E-6 1.34434073387 -0.58860951497 0.166110665075 0.001201565 01/17/2012 22190364 Patsopoulos NA 12/01/2011 Ann Neurol Multiple sclerosis 6p21.32 6 32413545 HLA-DRB1 HLA-DRA - HLA-DRB9 rs3129889-G rs3129889 3129889 Intergenic 2 0.20 1E-206 2.97 6 32437629 32438180 6 32413545 32413545 -0.846617291291 5.54764946813E-6 1.34434073387 -0.58860951497 0.166110665075 0.001201565 01/03/2011 21037568 Enciso-Mora V 10/31/2010 Nat Genet Hodgkin's lymphoma 6p21.32 6 32428285 HLA-DRA HLA-DRB9 - HLA-DRB5 rs6903608-G rs6903608 6903608 Intergenic 2 0.27 3E-50 1.70 6 32437629 32438180 6 32428285 32428285 -0.807864867543 1.2314308922E-6 1.14022837835 -0.619859650761 0.146102616352 3.363802E-4 11/25/2008 18836448 Franke A 10/05/2008 Nat Genet Ulcerative colitis 6p21.32 6 32431147 HLA-DRA, BTNL2 HLA-DRB9 - HLA-DRB5 rs9268877-T rs9268877 9268877 Intergenic 2 0.45 6E-18 1.45 6 32437629 32438180 6 32431147 32431147 -0.654738166058 1.72788016445E-5 0.744317460078 -0.562649446496 0.137428669861 0.003123412 12/11/2009 19915572 Barrett JC 11/15/2009 Nat Genet Ulcerative colitis 6p21.32 6 32431147 MHC HLA-DRB9 - HLA-DRB5 rs9268877-? rs9268877 9268877 Intergenic 2 NR 4E-23 NR 6 32437629 32438180 6 32431147 32431147 -0.654738166058 1.72788016445E-5 0.744317460078 -0.562649446496 0.137428669861 0.003123412 11/25/2008 18836448 Franke A 10/05/2008 Nat Genet Ulcerative colitis 6p21.32 6 32431147 HLA-DRA, BTNL2 HLA-DRB9 - HLA-DRB5 rs9268877-T rs9268877 9268877 Intergenic 2 0.45 6E-18 1.45 6 32401064 32401522 6 32431147 32431147 -0.491693523551 8.03723303077E-4 0.579862413381 -0.454632394657 0.13761233569 0.064872 12/11/2009 19915572 Barrett JC 11/15/2009 Nat Genet Ulcerative colitis 6p21.32 6 32431147 MHC HLA-DRB9 - HLA-DRB5 rs9268877-? rs9268877 9268877 Intergenic 2 NR 4E-23 NR 6 32401064 32401522 6 32431147 32431147 -0.491693523551 8.03723303077E-4 0.579862413381 -0.454632394657 0.13761233569 0.064872 11/25/2008 18836448 Franke A 10/05/2008 Nat Genet Ulcerative colitis 6p21.32 6 32431147 HLA-DRA, BTNL2 HLA-DRB9 - HLA-DRB5 rs9268877-T rs9268877 9268877 Intergenic 2 0.45 6E-18 1.45 6 32480153 32480422 6 32431147 32431147 -0.5563748208 2.33812473431E-4 0.65940850318 -0.493452965437 0.140097158725 0.02549014 12/11/2009 19915572 Barrett JC 11/15/2009 Nat Genet Ulcerative colitis 6p21.32 6 32431147 MHC HLA-DRB9 - HLA-DRB5 rs9268877-? rs9268877 9268877 Intergenic 2 NR 4E-23 NR 6 32480153 32480422 6 32431147 32431147 -0.5563748208 2.33812473431E-4 0.65940850318 -0.493452965437 0.140097158725 0.02549014 06/07/2011 21602797 Wright FA 05/22/2011 Nat Genet Cystic fibrosis severity 6p21.32 6 32432077 HLA-DRA HLA-DRB9 - HLA-DRB5 rs9268905-C rs9268905 9268905 Intergenic 2 0.32 1E-7 NR 6 32401064 32401522 6 32432077 32432077 -0.563546453373 4.12997323717E-4 0.484778622708 -0.476134614794 0.148687602578 0.03957892 06/07/2011 21602797 Wright FA 05/22/2011 Nat Genet Cystic fibrosis severity 6p21.32 6 32432077 HLA-DRA HLA-DRB9 - HLA-DRB5 rs9268905-C rs9268905 9268905 Intergenic 2 0.32 1E-7 NR 6 32480153 32480422 6 32432077 32432077 -0.589009433611 3.97251310043E-4 0.511735103283 -0.477347542463 0.154894984287 0.03836713 06/07/2011 21602797 Wright FA 05/22/2011 Nat Genet Cystic fibrosis severity 6p21.32 6 32432077 HLA-DRA HLA-DRB9 - HLA-DRB5 rs9268905-C rs9268905 9268905 Intergenic 2 0.32 1E-7 NR 6 32481878 32482301 6 32432077 32432077 -0.723906417557 1.66251373081E-5 0.615584415182 -0.563567756287 0.15158457711 0.003023766 03/24/2010 20228798 Franke A 03/14/2010 Nat Genet Ulcerative colitis 6p21.32 6 32432835 HLA-DRA HLA-DRB9 - HLA-DRB5 rs9268923-C rs9268923 9268923 Intergenic 2 0.67 4E-15 1.45 6 32401064 32401522 6 32432835 32432835 -0.563546453373 4.12997323717E-4 0.484778622708 -0.476134614794 0.148687602578 0.03957892 03/24/2010 20228798 Franke A 03/14/2010 Nat Genet Ulcerative colitis 6p21.32 6 32432835 HLA-DRA HLA-DRB9 - HLA-DRB5 rs9268923-C rs9268923 9268923 Intergenic 2 0.67 4E-15 1.45 6 32480153 32480422 6 32432835 32432835 -0.589009433611 3.97251310043E-4 0.511735103283 -0.477347542463 0.154894984287 0.03836713 03/24/2010 20228798 Franke A 03/14/2010 Nat Genet Ulcerative colitis 6p21.32 6 32432835 HLA-DRA HLA-DRB9 - HLA-DRB5 rs9268923-C rs9268923 9268923 Intergenic 2 0.67 4E-15 1.45 6 32481878 32482301 6 32432835 32432835 -0.723906417557 1.66251373081E-5 0.615584415182 -0.563567756287 0.15158457711 0.003023766 01/21/2009 19122664 Silverberg MS 01/04/2009 Nat Genet Ulcerative colitis 6p21.32 6 32433167 BTNL2, HLA-DRA, HLA-DRB5, HLA-DRB1, HLA-DQA1, HLA-DQB1 HLA-DRB9 - HLA-DRB5 rs2395185-? rs2395185 2395185 Intergenic 2 0.67 1E-16 1.52 6 32401064 32401522 6 32433167 32433167 -0.563546453373 4.12997323717E-4 0.484778622708 -0.476134614794 0.148687602578 0.03957892 02/23/2012 22286212 Urayama KY 01/27/2012 J Natl Cancer Inst Hodgkin's lymphoma 6p21.32 6 32433167 HLA-DRA HLA-DRB9 - HLA-DRB5 rs2395185-? rs2395185 2395185 Intergenic 2 NR 4E-31 1.82 6 32401064 32401522 6 32433167 32433167 -0.563546453373 4.12997323717E-4 0.484778622708 -0.476134614794 0.148687602578 0.03957892 12/14/2009 19915573 Asano K 11/15/2009 Nat Genet Ulcerative colitis 6p21.32 6 32433167 Intergenic HLA-DRB9 - HLA-DRB5 rs2395185-G rs2395185 2395185 Intergenic 2 0.61 5E-22 1.92 6 32401064 32401522 6 32433167 32433167 -0.563546453373 4.12997323717E-4 0.484778622708 -0.476134614794 0.148687602578 0.03957892 01/21/2009 19122664 Silverberg MS 01/04/2009 Nat Genet Ulcerative colitis 6p21.32 6 32433167 BTNL2, HLA-DRA, HLA-DRB5, HLA-DRB1, HLA-DQA1, HLA-DQB1 HLA-DRB9 - HLA-DRB5 rs2395185-? rs2395185 2395185 Intergenic 2 0.67 1E-16 1.52 6 32480153 32480422 6 32433167 32433167 -0.589009433611 3.97251310043E-4 0.511735103283 -0.477347542463 0.154894984287 0.03836713 02/23/2012 22286212 Urayama KY 01/27/2012 J Natl Cancer Inst Hodgkin's lymphoma 6p21.32 6 32433167 HLA-DRA HLA-DRB9 - HLA-DRB5 rs2395185-? rs2395185 2395185 Intergenic 2 NR 4E-31 1.82 6 32480153 32480422 6 32433167 32433167 -0.589009433611 3.97251310043E-4 0.511735103283 -0.477347542463 0.154894984287 0.03836713 12/14/2009 19915573 Asano K 11/15/2009 Nat Genet Ulcerative colitis 6p21.32 6 32433167 Intergenic HLA-DRB9 - HLA-DRB5 rs2395185-G rs2395185 2395185 Intergenic 2 0.61 5E-22 1.92 6 32480153 32480422 6 32433167 32433167 -0.589009433611 3.97251310043E-4 0.511735103283 -0.477347542463 0.154894984287 0.03836713 01/21/2009 19122664 Silverberg MS 01/04/2009 Nat Genet Ulcerative colitis 6p21.32 6 32433167 BTNL2, HLA-DRA, HLA-DRB5, HLA-DRB1, HLA-DQA1, HLA-DQB1 HLA-DRB9 - HLA-DRB5 rs2395185-? rs2395185 2395185 Intergenic 2 0.67 1E-16 1.52 6 32481878 32482301 6 32433167 32433167 -0.723906417557 1.66251373081E-5 0.615584415182 -0.563567756287 0.15158457711 0.003023766 02/23/2012 22286212 Urayama KY 01/27/2012 J Natl Cancer Inst Hodgkin's lymphoma 6p21.32 6 32433167 HLA-DRA HLA-DRB9 - HLA-DRB5 rs2395185-? rs2395185 2395185 Intergenic 2 NR 4E-31 1.82 6 32481878 32482301 6 32433167 32433167 -0.723906417557 1.66251373081E-5 0.615584415182 -0.563567756287 0.15158457711 0.003023766 12/14/2009 19915573 Asano K 11/15/2009 Nat Genet Ulcerative colitis 6p21.32 6 32433167 Intergenic HLA-DRB9 - HLA-DRB5 rs2395185-G rs2395185 2395185 Intergenic 2 0.61 5E-22 1.92 6 32481878 32482301 6 32433167 32433167 -0.723906417557 1.66251373081E-5 0.615584415182 -0.563567756287 0.15158457711 0.003023766 11/25/2008 18758464 Kugathasan S 08/31/2008 Nat Genet Inflammatory bowel disease 6p21.32 6 32569691 HLA-DQA1 HLA-DRB1 - HLA-DQA1 rs477515-? rs477515 477515 Intergenic 2 0.69 1E-8 1.38 6 32576177 32576626 6 32569691 32569691 -0.878585938715 3.45325447555E-6 0.70652363261 -0.598814104261 0.167867259676 8.091993E-4 11/25/2008 18758464 Kugathasan S 08/31/2008 Nat Genet Inflammatory bowel disease 6p21.32 6 32569691 HLA-DQA1 HLA-DRB1 - HLA-DQA1 rs477515-? rs477515 477515 Intergenic 2 0.69 1E-8 1.38 6 32590158 32590600 6 32569691 32569691 -0.775928048918 6.97525411647E-6 0.602905431861 -0.583552627536 0.154255158474 0.001456905 11/25/2008 18758464 Kugathasan S 08/31/2008 Nat Genet Inflammatory bowel disease 6p21.32 6 32569691 HLA-DQA1 HLA-DRB1 - HLA-DQA1 rs477515-? rs477515 477515 Intergenic 2 0.69 1E-8 1.38 6 32606268 32606662 6 32569691 32569691 -0.920941825592 1.0092918184E-6 0.738140145474 -0.623749481939 0.164862554751 2.830783E-4 11/25/2008 18758464 Kugathasan S 08/31/2008 Nat Genet Inflammatory bowel disease 6p21.32 6 32569691 HLA-DQA1 HLA-DRB1 - HLA-DQA1 rs477515-? rs477515 477515 Intergenic 2 0.69 1E-8 1.38 6 32610482 32611057 6 32569691 32569691 -0.947449651245 2.71102129793E-8 0.764260032677 -0.686313595142 0.143434134587 1.23905E-5 11/25/2008 18758464 Kugathasan S 08/31/2008 Nat Genet Inflammatory bowel disease 6p21.32 6 32569691 HLA-DQA1 HLA-DRB1 - HLA-DQA1 rs477515-? rs477515 477515 Intergenic 2 0.69 1E-8 1.38 6 32526456 32526838 6 32569691 32569691 -0.632772003448 1.26577144957E-5 0.539549033593 -0.569983168844 0.130309899511 0.002406567 11/25/2008 18758464 Kugathasan S 08/31/2008 Nat Genet Inflammatory bowel disease 6p21.32 6 32569691 HLA-DQA1 HLA-DRB1 - HLA-DQA1 rs477515-? rs477515 477515 Intergenic 2 0.69 1E-8 1.38 6 32542670 32543058 6 32569691 32569691 -0.864883629385 2.26732069572E-9 0.72054946378 -0.72184612958 0.118455362919 1.437299E-6 11/25/2008 18758464 Kugathasan S 08/31/2008 Nat Genet Inflammatory bowel disease 6p21.32 6 32569691 HLA-DQA1 HLA-DRB1 - HLA-DQA1 rs477515-? rs477515 477515 Intergenic 2 0.69 1E-8 1.38 6 32551518 32551990 6 32569691 32569691 -0.642895177649 1.26964901152E-5 0.526015223442 -0.569911935752 0.132419125768 0.002412585 11/25/2008 18758464 Kugathasan S 08/31/2008 Nat Genet Inflammatory bowel disease 6p21.32 6 32569691 HLA-DQA1 HLA-DRB1 - HLA-DQA1 rs477515-? rs477515 477515 Intergenic 2 0.69 1E-8 1.38 6 32552026 32552398 6 32569691 32569691 -0.828337259525 5.6514955248E-6 0.673436257724 -0.588203118029 0.162695815678 0.001219876 11/09/2009 19838193 Han JW 10/18/2009 Nat Genet Systemic lupus erythematosus 6p21.32 6 32576478 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs9271100-? rs9271100 9271100 Intergenic 2 NR 1E-12 1.90 6 32576177 32576626 6 32576478 32576478 -0.510091722105 0.0012382556851 0.55030836258 -0.439884481548 0.148769609463 0.08836848 11/09/2009 19838193 Han JW 10/18/2009 Nat Genet Systemic lupus erythematosus 6p21.32 6 32576478 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs9271100-? rs9271100 9271100 Intergenic 2 NR 1E-12 1.90 6 32590158 32590600 6 32576478 32576478 -0.571432704961 3.72636001006E-5 0.595371093963 -0.543758755445 0.12599339497 0.005887631 11/09/2009 19838193 Han JW 10/18/2009 Nat Genet Systemic lupus erythematosus 6p21.32 6 32576478 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs9271100-? rs9271100 9271100 Intergenic 2 NR 1E-12 1.90 6 32526456 32526838 6 32576478 32576478 -0.40128905646 7.40476799254E-4 0.463612679945 -0.457356319671 0.111466622212 0.06131954 11/09/2009 19838193 Han JW 10/18/2009 Nat Genet Systemic lupus erythematosus 6p21.32 6 32576478 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs9271100-? rs9271100 9271100 Intergenic 2 NR 1E-12 1.90 6 32542670 32543058 6 32576478 32576478 -0.449869463902 4.27303910088E-4 0.510404203188 -0.475068312164 0.119039165524 0.04058227 01/24/2012 22197929 Yu XQ 12/25/2011 Nat Genet IgA nephropathy 6p21.32 6 32577380 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs660895-G rs660895 660895 Intergenic 2 0.24 4E-20 1.34 6 32610482 32611057 6 32577380 32577380 -0.710933446967 9.9785099466E-4 0.462600582655 -0.44733227296 0.203056478694 0.07581814 11/25/2008 17804836 Plenge RM 09/05/2007 N Engl J Med Rheumatoid arthritis 6p21.32 6 32577380 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs660895-? rs660895 660895 Intergenic 2 0.21 1E-108 3.62 6 32610482 32611057 6 32577380 32577380 -0.710933446967 9.9785099466E-4 0.462600582655 -0.44733227296 0.203056478694 0.07581814 01/24/2012 22197929 Yu XQ 12/25/2011 Nat Genet IgA nephropathy 6p21.32 6 32577380 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs660895-G rs660895 660895 Intergenic 2 0.24 4E-20 1.34 6 32542670 32543058 6 32577380 32577380 -0.650329015162 4.78938367618E-4 0.446051987222 -0.47147091859 0.173776268479 0.04417526 11/25/2008 17804836 Plenge RM 09/05/2007 N Engl J Med Rheumatoid arthritis 6p21.32 6 32577380 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs660895-? rs660895 660895 Intergenic 2 0.21 1E-108 3.62 6 32542670 32543058 6 32577380 32577380 -0.650329015162 4.78938367618E-4 0.446051987222 -0.47147091859 0.173776268479 0.04417526 06/30/2009 19525955 Bahlo 06/14/2009 Nat Genet Multiple sclerosis 6p21.32 6 32586854 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs9271366-G rs9271366 9271366 Intergenic 2 0.15 7E-184 2.78 6 32551518 32551990 6 32586854 32586854 -0.425436186464 7.59050662552E-4 0.60145183041 -0.456535329928 0.118442663478 0.06237854 07/12/2011 21699788 Okada Y 06/20/2011 Gastroenterology Inflammatory bowel disease 6p21.32 6 32586854 MHC HLA-DRB1 - HLA-DQA1 rs9271366-C rs9271366 9271366 Intergenic 2 0.21 2E-70 4.44 6 32551518 32551990 6 32586854 32586854 -0.425436186464 7.59050662552E-4 0.60145183041 -0.456535329928 0.118442663478 0.06237854 07/12/2011 21699788 Okada Y 06/20/2011 Gastroenterology Inflammatory bowel disease 6p21.32 6 32586854 MHC HLA-DRB1 - HLA-DQA1 rs9271366-C rs9271366 9271366 Intergenic 2 0.21 3E-31 2.41 6 32551518 32551990 6 32586854 32586854 -0.425436186464 7.59050662552E-4 0.60145183041 -0.456535329928 0.118442663478 0.06237854 07/12/2011 21699788 Okada Y 06/20/2011 Gastroenterology Inflammatory bowel disease 6p21.32 6 32586854 MHC HLA-DRB1 - HLA-DQA1 rs9271366-T rs9271366 9271366 Intergenic 2 0.79 8E-11 1.79 6 32551518 32551990 6 32586854 32586854 -0.425436186464 7.59050662552E-4 0.60145183041 -0.456535329928 0.118442663478 0.06237854 07/14/2010 20598377 Nischwitz S 06/30/2010 J Neuroimmunol Multiple sclerosis 6p21.32 6 32586854 DQA1 HLA-DRB1 - HLA-DQA1 rs9271366-G rs9271366 9271366 Intergenic 2 NR 4E-17 2.62 6 32551518 32551990 6 32586854 32586854 -0.425436186464 7.59050662552E-4 0.60145183041 -0.456535329928 0.118442663478 0.06237854 09/21/2010 20694011 Ferreira RC 08/08/2010 Nat Genet Immunoglobulin A 6p21.32 6 32586854 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs9271366-? rs9271366 9271366 Intergenic 2 0.85 3E-33 7.69 6 32551518 32551990 6 32586854 32586854 -0.425436186464 7.59050662552E-4 0.60145183041 -0.456535329928 0.118442663478 0.06237854 06/30/2009 19525955 Bahlo 06/14/2009 Nat Genet Multiple sclerosis 6p21.32 6 32586854 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs9271366-G rs9271366 9271366 Intergenic 2 0.15 7E-184 2.78 6 32552026 32552398 6 32586854 32586854 -0.512844306189 0.00120486502606 0.721477789075 -0.440837005949 0.149171580772 0.0867382 07/12/2011 21699788 Okada Y 06/20/2011 Gastroenterology Inflammatory bowel disease 6p21.32 6 32586854 MHC HLA-DRB1 - HLA-DQA1 rs9271366-C rs9271366 9271366 Intergenic 2 0.21 2E-70 4.44 6 32552026 32552398 6 32586854 32586854 -0.512844306189 0.00120486502606 0.721477789075 -0.440837005949 0.149171580772 0.0867382 07/12/2011 21699788 Okada Y 06/20/2011 Gastroenterology Inflammatory bowel disease 6p21.32 6 32586854 MHC HLA-DRB1 - HLA-DQA1 rs9271366-C rs9271366 9271366 Intergenic 2 0.21 3E-31 2.41 6 32552026 32552398 6 32586854 32586854 -0.512844306189 0.00120486502606 0.721477789075 -0.440837005949 0.149171580772 0.0867382 07/12/2011 21699788 Okada Y 06/20/2011 Gastroenterology Inflammatory bowel disease 6p21.32 6 32586854 MHC HLA-DRB1 - HLA-DQA1 rs9271366-T rs9271366 9271366 Intergenic 2 0.79 8E-11 1.79 6 32552026 32552398 6 32586854 32586854 -0.512844306189 0.00120486502606 0.721477789075 -0.440837005949 0.149171580772 0.0867382 07/14/2010 20598377 Nischwitz S 06/30/2010 J Neuroimmunol Multiple sclerosis 6p21.32 6 32586854 DQA1 HLA-DRB1 - HLA-DQA1 rs9271366-G rs9271366 9271366 Intergenic 2 NR 4E-17 2.62 6 32552026 32552398 6 32586854 32586854 -0.512844306189 0.00120486502606 0.721477789075 -0.440837005949 0.149171580772 0.0867382 09/21/2010 20694011 Ferreira RC 08/08/2010 Nat Genet Immunoglobulin A 6p21.32 6 32586854 HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs9271366-? rs9271366 9271366 Intergenic 2 0.85 3E-33 7.69 6 32552026 32552398 6 32586854 32586854 -0.512844306189 0.00120486502606 0.721477789075 -0.440837005949 0.149171580772 0.0867382 05/25/2011 21502966 Weber F 04/19/2011 Pharmacogenomics J Response to interferon beta therapy 6p21.32 6 32599999 HLA-DQA1, HLA-DRB1 HLA-DRB1 - HLA-DQA1 rs9272105-A rs9272105 9272105 Intergenic 2 0.44 4E-10 .26 6 32595487 32595898 6 32599999 32599999 -0.923683662018 5.07005844907E-5 0.65478255633 -0.535858413481 0.207910297468 0.007551663 11/25/2008 17554300 WTCCC 06/07/2007 Nature Type 1 diabetes 6p21.32 6 32604372 MHC HLA-DQA1 rs9272346-G rs9272346 9272346 nearGene-5 1 0.61 5E-134 5.49 6 32576177 32576626 6 32604372 32604372 -0.894147854582 1.31723374003E-6 0.946954233788 -0.618530504206 0.162270856418 3.558E-4 11/25/2008 18978792 Cooper JD 11/02/2008 Nat Genet Type 1 diabetes 6p21.32 6 32604372 HLA HLA-DQA1 rs9272346-G rs9272346 9272346 nearGene-5 1 NR 6E-129 NR 6 32576177 32576626 6 32604372 32604372 -0.894147854582 1.31723374003E-6 0.946954233788 -0.618530504206 0.162270856418 3.558E-4 11/25/2008 17554300 WTCCC 06/07/2007 Nature Type 1 diabetes 6p21.32 6 32604372 MHC HLA-DQA1 rs9272346-G rs9272346 9272346 nearGene-5 1 0.61 5E-134 5.49 6 32590158 32590600 6 32604372 32604372 -0.783763240092 3.54536010414E-6 0.80898709773 -0.59825657328 0.14996745133 8.262107E-4 11/25/2008 18978792 Cooper JD 11/02/2008 Nat Genet Type 1 diabetes 6p21.32 6 32604372 HLA HLA-DQA1 rs9272346-G rs9272346 9272346 nearGene-5 1 NR 6E-129 NR 6 32590158 32590600 6 32604372 32604372 -0.783763240092 3.54536010414E-6 0.80898709773 -0.59825657328 0.14996745133 8.262107E-4 11/25/2008 17554300 WTCCC 06/07/2007 Nature Type 1 diabetes 6p21.32 6 32604372 MHC HLA-DQA1 rs9272346-G rs9272346 9272346 nearGene-5 1 0.61 5E-134 5.49 6 32606268 32606662 6 32604372 32604372 -1.00721245337 1.82005384547E-8 1.06423539317 -0.692377742753 0.149946895341 8.75266E-6 11/25/2008 18978792 Cooper JD 11/02/2008 Nat Genet Type 1 diabetes 6p21.32 6 32604372 HLA HLA-DQA1 rs9272346-G rs9272346 9272346 nearGene-5 1 NR 6E-129 NR 6 32606268 32606662 6 32604372 32604372 -1.00721245337 1.82005384547E-8 1.06423539317 -0.692377742753 0.149946895341 8.75266E-6 11/25/2008 17554300 WTCCC 06/07/2007 Nature Type 1 diabetes 6p21.32 6 32604372 MHC HLA-DQA1 rs9272346-G rs9272346 9272346 nearGene-5 1 0.61 5E-134 5.49 6 32610482 32611057 6 32604372 32604372 -1.08422992367 2.58307366916E-12 1.15059297733 -0.797134970251 0.117323613154 3.878204E-9 11/25/2008 18978792 Cooper JD 11/02/2008 Nat Genet Type 1 diabetes 6p21.32 6 32604372 HLA HLA-DQA1 rs9272346-G rs9272346 9272346 nearGene-5 1 NR 6E-129 NR 6 32610482 32611057 6 32604372 32604372 -1.08422992367 2.58307366916E-12 1.15059297733 -0.797134970251 0.117323613154 3.878204E-9 11/25/2008 17554300 WTCCC 06/07/2007 Nature Type 1 diabetes 6p21.32 6 32604372 MHC HLA-DQA1 rs9272346-G rs9272346 9272346 nearGene-5 1 0.61 5E-134 5.49 6 32630685 32631099 6 32604372 32604372 -0.83703464329 4.56098480112E-6 0.895736471577 -0.592867533481 0.162422212866 0.001014731 11/25/2008 18978792 Cooper JD 11/02/2008 Nat Genet Type 1 diabetes 6p21.32 6 32604372 HLA HLA-DQA1 rs9272346-G rs9272346 9272346 nearGene-5 1 NR 6E-129 NR 6 32630685 32631099 6 32604372 32604372 -0.83703464329 4.56098480112E-6 0.895736471577 -0.592867533481 0.162422212866 0.001014731 05/27/2011 21570397 Lucena MI 04/12/2011 Gastroenterology Drug-induced liver injury (amoxicillin-clavulanate) 6p21.32 6 32632832 HLA-DRB1-DQB1 HLA-DQB1 rs9274407-? rs9274407 9274407 missense;missense 1 NR 5E-14 3.10 6 32590158 32590600 6 32632832 32632832 -0.969487915224 2.33983635586E-7 1.42384722699 -0.650795848299 0.161579391909 8.101885E-5 05/27/2011 21570397 Lucena MI 04/12/2011 Gastroenterology Drug-induced liver injury (amoxicillin-clavulanate) 6p21.32 6 32632832 HLA-DRB1-DQB1 HLA-DQB1 rs9274407-? rs9274407 9274407 missense;missense 1 NR 5E-14 3.10 6 32606268 32606662 6 32632832 32632832 -1.12076222675 4.74557700609E-8 1.66793062358 -0.677540534336 0.173801787814 2.018044E-5 05/27/2011 21570397 Lucena MI 04/12/2011 Gastroenterology Drug-induced liver injury (amoxicillin-clavulanate) 6p21.32 6 32632832 HLA-DRB1-DQB1 HLA-DQB1 rs9274407-? rs9274407 9274407 missense;missense 1 NR 5E-14 3.10 6 32610482 32611057 6 32632832 32632832 -0.753312775231 2.89437145898E-4 1.12516856633 -0.487063505944 0.192969316873 0.03009483 05/27/2011 21570397 Lucena MI 04/12/2011 Gastroenterology Drug-induced liver injury (amoxicillin-clavulanate) 6p21.32 6 32632832 HLA-DRB1-DQB1 HLA-DQB1 rs9274407-? rs9274407 9274407 missense;missense 1 NR 5E-14 3.10 6 32630685 32631099 6 32632832 32632832 -0.743829526402 6.17241578633E-4 1.11791633959 -0.463326813335 0.203242043843 0.05355255 04/12/2011 21399635 Mells GF 03/13/2011 Nat Genet Primary biliary cirrhosis 6p21.32 6 32657578 MHC HLA-DQB1 - HLA-DQA2 rs7774434-C rs7774434 7774434 Intergenic 2 0.38 4E-34 1.60 6 32630685 32631099 6 32657578 32657578 -0.637345614016 5.78945750259E-4 0.584325246226 -0.465402156484 0.173157211992 0.05100128 09/02/2010 20639880 Liu X 07/18/2010 Nat Genet Primary biliary cirrhosis 6p21.32 6 32657578 HLA-DQB1 HLA-DQB1 - HLA-DQA2 rs7774434-C rs7774434 7774434 Intergenic 2 0.371 3E-26 1.75 6 32630685 32631099 6 32657578 32657578 -0.637345614016 5.78945750259E-4 0.584325246226 -0.465402156484 0.173157211992 0.05100128 08/27/2011 21804548 Hirota T 07/31/2011 Nat Genet Asthma 6p21.32 6 32658079 HLA-DQB1 HLA-DQB1 - HLA-DQA2 rs7775228-A rs7775228 7775228 Intergenic 2 0.63 5E-15 1.17 6 32630685 32631099 6 32658079 32658079 -0.972789598676 0.00147591695566 0.219281860749 -0.433700325577 0.288724393731 0.09964236 12/01/2011 22036096 Ramasamy A 11/01/2011 J Allergy Clin Immunol IgE grass sensitization 6p21.32 6 32658079 HLA region HLA-DQB1 - HLA-DQA2 rs7775228-C rs7775228 7775228 Intergenic 2 0.13 2E-9 1.33 6 32630685 32631099 6 32658079 32658079 -0.972789598676 0.00147591695566 0.219281860749 -0.433700325577 0.288724393731 0.09964236 11/25/2008 17554300 WTCCC 06/07/2007 Nature Crohn's disease 6p21.32 6 32658310 NR HLA-DQB1 - HLA-DQA2 rs9469220-A rs9469220 9469220 Intergenic 2 0.48 2E-6 1.14 6 32630685 32631099 6 32658310 32658310 -0.660572459755 2.80876201471E-4 0.514608142024 -0.48796999185 0.168800644814 0.02939438 05/25/2012 22493691 Eriksson N 04/06/2012 PLoS One Hypothyroidism 6p21.32 6 32663631 HLA-DRB9, HLA-DRB5, HLA-DRB1, HLA-DQA1, HLA-DQB1, HLA-DQA2 HLA-DQB1 - HLA-DQA2 rs3129720-C rs3129720 3129720 Intergenic 2 0.764 5E-7 1.16 6 32630685 32631099 6 32663631 32663631 -1.16249508806 9.6400583764E-12 1.65063403241 -0.784554487782 0.131251298282 1.210627E-8 05/25/2012 22493691 Eriksson N 04/06/2012 PLoS One Hypothyroidism 6p21.32 6 32663631 HLA-DRB9, HLA-DRB5, HLA-DRB1, HLA-DQA1, HLA-DQB1, HLA-DQA2 HLA-DQB1 - HLA-DQA2 rs3129720-C rs3129720 3129720 Intergenic 2 0.764 5E-7 1.16 6 32659812 32660205 6 32663631 32663631 -0.373064158762 0.00115313088585 0.462914568176 -0.4423605231 0.108049507967 0.08414238 05/03/2010 20383147 Radstake TR 04/11/2010 Nat Genet Systemic sclerosis 6p21.32 6 32663851 HLA-DQB1 HLA-DQB1 - HLA-DQA2 rs6457617-? rs6457617 6457617 Intergenic 2 0.53 4E-17 1.37 6 32659812 32660205 6 32663851 32663851 -0.567549956799 3.67442933421E-8 0.49265728208 -0.681586291021 0.0870443659368 1.614744E-5 08/03/2011 21750679 Allanore Y 07/07/2011 PLoS Genet Systemic sclerosis 6p21.32 6 32663851 HLA, DQB1 HLA-DQB1 - HLA-DQA2 rs6457617-T rs6457617 6457617 Intergenic 2 0.50 2E-37 1.61 6 32659812 32660205 6 32663851 32663851 -0.567549956799 3.67442933421E-8 0.49265728208 -0.681586291021 0.0870443659368 1.614744E-5 09/21/2011 21841780 Chu X 08/14/2011 Nat Genet Graves' disease 6p21.32 6 32663851 HLA, DRB1, DQA1, DQB1 HLA-DQB1 - HLA-DQA2 rs6457617-T rs6457617 6457617 Intergenic 2 0.45 7E-33 1.40 6 32659812 32660205 6 32663851 32663851 -0.567549956799 3.67442933421E-8 0.49265728208 -0.681586291021 0.0870443659368 1.614744E-5 11/25/2008 17554300 WTCCC 06/07/2007 Nature Rheumatoid arthritis 6p21.32 6 32663851 MHC HLA-DQB1 - HLA-DQA2 rs6457617-T rs6457617 6457617 Intergenic 2 0.49 5E-75 2.36 6 32659812 32660205 6 32663851 32663851 -0.567549956799 3.67442933421E-8 0.49265728208 -0.681586291021 0.0870443659368 1.614744E-5 11/25/2008 18668548 Julia A 08/01/2008 Arthritis Rheum Rheumatoid arthritis 6p21.32 6 32663851 HLA-DQA1, HLA-DQA2 HLA-DQB1 - HLA-DQA2 rs6457617-? rs6457617 6457617 Intergenic 2 NR 1E-9 NR 6 32659812 32660205 6 32663851 32663851 -0.567549956799 3.67442933421E-8 0.49265728208 -0.681586291021 0.0870443659368 1.614744E-5 11/25/2008 18794853 Raychaudhuri S 09/14/2008 Nat Genet Rheumatoid arthritis 6p21.32 6 32663999 HLA-DRB1 HLA-DQB1 - HLA-DQA2 rs6457620-? rs6457620 6457620 Intergenic 2 0.50 4E-186 2.55 6 32659812 32660205 6 32663999 32663999 -0.567549956799 3.67442933421E-8 0.49265728208 -0.681586291021 0.0870443659368 1.614744E-5 04/07/2011 21408207 Chung SA 03/03/2011 PLoS Genet Systemic lupus erythematosus 6p21.32 6 32664458 HLA-DQA1, HLA-DQA2 HLA-DQB1 - HLA-DQA2 rs2647012-A rs2647012 2647012 Intergenic 2 0.44 8E-6 1.38 6 32630685 32631099 6 32664458 32664458 -0.80911890134 4.47721804778E-6 0.945504009644 -0.593267446081 0.156842081192 0.001001205 05/25/2011 21533074 Smedby KE 04/21/2011 PLoS Genet Follicular lymphoma 6p21.32 6 32664458 HLA-DQB1 HLA-DQB1 - HLA-DQA2 rs2647012-G rs2647012 2647012 Intergenic 2 0.56 2E-21 1.56 6 32630685 32631099 6 32664458 32664458 -0.80911890134 4.47721804778E-6 0.945504009644 -0.593267446081 0.156842081192 0.001001205 04/07/2011 21408207 Chung SA 03/03/2011 PLoS Genet Systemic lupus erythematosus 6p21.32 6 32664458 HLA-DQA1, HLA-DQA2 HLA-DQB1 - HLA-DQA2 rs2647012-A rs2647012 2647012 Intergenic 2 0.44 8E-6 1.38 6 32659812 32660205 6 32664458 32664458 -0.417323431089 4.73761229071E-5 0.41902168589 -0.537615513493 0.0935036233282 0.007147625 05/25/2011 21533074 Smedby KE 04/21/2011 PLoS Genet Follicular lymphoma 6p21.32 6 32664458 HLA-DQB1 HLA-DQB1 - HLA-DQA2 rs2647012-G rs2647012 2647012 Intergenic 2 0.56 2E-21 1.56 6 32659812 32660205 6 32664458 32664458 -0.417323431089 4.73761229071E-5 0.41902168589 -0.537615513493 0.0935036233282 0.007147625 08/12/2011 21779181 Gorlova O 07/14/2011 PLoS Genet Systemic sclerosis 6p21.32 6 32669156 HLA-DQB1 HLA-DQB1 - HLA-DQA2 rs9275390-? rs9275390 9275390 Intergenic 2 0.25 3E-54 2.38 6 32659812 32660205 6 32669156 32669156 -0.39777970015 1.89028484191E-4 0.201422222573 -0.499696192981 0.0985047297026 0.02155748 08/12/2011 21779181 Gorlova O 07/14/2011 PLoS Genet Systemic sclerosis 6p21.32 6 32669156 HLA-DQB1 HLA-DQB1 - HLA-DQA2 rs9275390-? rs9275390 9275390 Intergenic 2 0.75 1E-7 1.61 6 32659812 32660205 6 32669156 32669156 -0.39777970015 1.89028484191E-4 0.201422222573 -0.499696192981 0.0985047297026 0.02155748 05/11/2011 21499248 Kumar V 04/17/2011 Nat Genet Hepatocellular carcinoma 6p21.32 6 32678999 HLA-DQ, HLA-DR HLA-DQB1 - HLA-DQA2 rs9275572-A rs9275572 9275572 Intergenic 2 0.36 6E-9 1.30 6 32630685 32631099 6 32678999 32678999 -0.72902740508 6.85122825286E-5 0.83855448642 -0.527938166234 0.167538679798 0.009660936 08/12/2010 20596022 Petukhova L 07/01/2010 Nature Alopecia areata 6p21.32 6 32678999 HLA-DQA2 HLA-DQB1 - HLA-DQA2 rs9275572-G rs9275572 9275572 Intergenic 2 0.59 1E-35 2.21 6 32630685 32631099 6 32678999 32678999 -0.72902740508 6.85122825286E-5 0.83855448642 -0.527938166234 0.167538679798 0.009660936 04/16/2009 19349983 Kamatani Y 04/06/2009 Nat Genet Hepatitis B 6p21.32 6 33054861 HLA-DPB1 HLA-DPB1 rs9277535-G rs9277535 9277535 UTR-3;UTR-3 1 NR 6E-39 1.75 6 33050488 33050916 6 33054861 33054861 0.809830944132 3.42571258736E-5 -0.464247712615 0.545883057899 0.177569708955 0.005500652 08/05/2011 21750111 Mbarek H 07/12/2011 Hum Mol Genet Hepatitis B 6p21.32 6 33054861 HLA-DPB1 HLA-DPB1 rs9277535-G rs9277535 9277535 UTR-3;UTR-3 1 0.57 3E-54 1.77 6 33050488 33050916 6 33054861 33054861 0.809830944132 3.42571258736E-5 -0.464247712615 0.545883057899 0.177569708955 0.005500652 08/06/2011 21764829 Png E 07/15/2011 Hum Mol Genet Hepatitis B vaccine response 6p21.32 6 33054861 HLA-DPB1 HLA-DPB1 rs9277535-? rs9277535 9277535 UTR-3;UTR-3 1 NR 3E-12 1.39 6 33050488 33050916 6 33054861 33054861 0.809830944132 3.42571258736E-5 -0.464247712615 0.545883057899 0.177569708955 0.005500652 04/12/2011 21399633 Gharavi AG 03/13/2011 Nat Genet Nephropathy 6p21.32 6 33086448 HLA-DPA1, HLA-DPB1, HLA-DPB2 HLA-DPB2 rs1883414-? rs1883414 1883414 1 0.67 (EA) 5E-9 1.28 6 33050488 33050916 6 33086448 33086448 0.604269907129 0.00116953889032 -0.398784390898 0.441870811193 0.175254087325 0.08501704 04/03/2012 22423221 Qayyum R 03/08/2012 PLoS Genet Mean platelet volume 6p21.31 6 33540209 BAK1 BAK1 rs210134-G rs210134 210134 nearGene-3 1 0.286 2E-15 6.16 6 33546527 33546961 6 33540209 33540209 -0.864696879186 5.14664792887E-6 1.23693190459 -0.590248020819 0.168936804031 0.001126859 01/25/2012 20686565 Teslovich TM 08/05/2010 Nature Cholesterol, total 6p21.31 6 34546560 C6orf106 SPDEF - C6orf106 rs2814982-T rs2814982 2814982 Intergenic 2 0.11 5E-11 1.86 6 34551133 34551602 6 34546560 34546560 1.29013793334 8.11547561905E-5 -0.3058904889 0.523395100149 0.300050241614 0.01109619 01/25/2012 20686565 Teslovich TM 08/05/2010 Nature HDL cholesterol 6p21.31 6 34552797 C6orf106 SPDEF - C6orf106 rs2814944-A rs2814944 2814944 Intergenic 2 0.16 4E-9 .49 6 34551133 34551602 6 34552797 34552797 1.13895390493 1.00210459052E-4 -0.289685813127 0.517645003061 0.268933293814 0.01310588 09/27/2011 21901158 Irvin MR 08/25/2011 PLoS One Insulin resistance/response 6p21.2 6 38036420 ZFAND3 ZFAND3 rs17589516-C rs17589516 17589516 intron 1 0.02 4E-6 45.00 6 37992056 37992568 6 38036420 38036420 -1.4452330039 7.19390894464E-4 0.192091982039 -0.458311108564 0.400386571792 0.05997972 12/09/2008 18846501 Sonuga-Barke EJ 10/07/2008 Am J Med Genet B Neuropsychiatr Genet Attention deficit hyperactivity disorder symptoms (interaction) 6p21.2 6 39539207 KIF6 KIF6 rs4714261-T rs4714261 4714261 intron 1 0.17 2E-6 .95 6 39522838 39523238 6 39539207 39539207 0.784283977833 1.23636342229E-4 -0.288667198723 0.5118135617 0.18806392129 0.01549869 10/29/2010 20889312 Wang KS 10/01/2010 Schizophr Res Bipolar disorder and schizophrenia 6q15 6 89732101 GABRR1 CYCSP16 - PNRC1 rs12201676-C rs12201676 12201676 Intergenic 2 NR 4E-8 1.31 6 89685070 89685472 6 89732101 89732101 0.86269632978 5.07472784438E-4 -0.336468901127 0.469630774792 0.231684318099 0.04612762 11/25/2008 17434096 Matarin M 05/06/2007 Lancet Neurol Stroke 6q21 6 106987370 AIM1 AIM1 rs783396-? rs783396 783396 missense 1 0.90 9E-6 2.17 6 106971643 106972117 6 106987370 106987370 0.486237573052 0.00148203190919 -0.763230184884 0.433553294665 0.144375809845 0.0999653 11/25/2008 17982456 Plenge RM 11/04/2007 Nat Genet Rheumatoid arthritis 6q23.3 6 138002637 TNFAIP3, OLIG3 OLIG3 - TNFAIP3 rs10499194-C rs10499194 10499194 Intergenic 2 0.71 1E-9 1.33 6 138018472 138018864 6 138002637 138002637 -1.12102243809 5.23732563291E-7 0.524511732451 -0.636212549425 0.194203811966 1.610022E-4 10/19/2011 21926972 Sklar P 09/18/2011 Nat Genet Bipolar disorder 6q25.2 6 152790573 SYNE1 SYNE1 rs9371601-T rs9371601 9371601 intron 1 NR 7E-7 1.10 6 152806745 152807196 6 152790573 152790573 -0.612265018451 0.00104333773566 0.393325770396 -0.445807912599 0.17562207067 0.07839285 06/22/2010 20526339 Quan C 06/06/2010 Nat Genet Vitiligo 6q27 6 167360389 RNASET2, FGFR1OP, CCR6 RNASET2 rs2236313-T rs2236313 2236313 intron 1 0.38 1E-16 1.20 6 167403118 167403519 6 167360389 167360389 0.717315288586 1.40636855981E-7 -0.580729992152 0.659624442246 0.116761428996 5.226207E-5 09/21/2011 21841780 Chu X 08/14/2011 Nat Genet Graves' disease 6q27 6 167383075 RNASET2, FGFR1OP RNASET2 - FGFR1OP rs9355610-G rs9355610 9355610 Intergenic 2 0.47 7E-10 1.19 6 167403118 167403519 6 167383075 167383075 0.644298256115 1.85255653644E-5 -0.423827044793 0.560983461238 0.135824604691 0.003307364 09/21/2011 21841780 Chu X 08/14/2011 Nat Genet Graves' disease 6q27 6 167383075 RNASET2, FGFR1OP RNASET2 - FGFR1OP rs9355610-G rs9355610 9355610 Intergenic 2 0.47 7E-10 1.19 6 167411229 167411651 6 167383075 167383075 0.53378855173 5.42788303388E-5 -0.33664184386 0.534081633351 0.120709853425 0.007981024 07/12/2010 20570966 McGovern DP 06/22/2010 Hum Mol Genet Crohn's disease 6q27 6 167437988 CCR6,FGFR10P,RNASE2 FGFR1OP rs2301436-? rs2301436 2301436 intron 1 NR 6E-8 1.37 6 167403118 167403519 6 167437988 167437988 -0.688387337337 3.84554644618E-7 0.656192565869 -0.641894678794 0.117475984264 1.236265E-4 11/25/2008 18587394 Barrett JC 06/29/2008 Nat Genet Crohn's disease 6q27 6 167437988 CCR6 FGFR1OP rs2301436-T rs2301436 2301436 intron 1 0.46 1E-12 1.21 6 167403118 167403519 6 167437988 167437988 -0.688387337337 3.84554644618E-7 0.656192565869 -0.641894678794 0.117475984264 1.236265E-4 07/12/2010 20570966 McGovern DP 06/22/2010 Hum Mol Genet Crohn's disease 6q27 6 167437988 CCR6,FGFR10P,RNASE2 FGFR1OP rs2301436-? rs2301436 2301436 intron 1 NR 6E-8 1.37 6 167411229 167411651 6 167437988 167437988 -0.456995726683 2.65290183427E-4 0.444813590738 -0.489686721482 0.116241626764 0.0280577 11/25/2008 18587394 Barrett JC 06/29/2008 Nat Genet Crohn's disease 6q27 6 167437988 CCR6 FGFR1OP rs2301436-T rs2301436 2301436 intron 1 0.46 1E-12 1.21 6 167411229 167411651 6 167437988 167437988 -0.456995726683 2.65290183427E-4 0.444813590738 -0.489686721482 0.116241626764 0.0280577 04/22/2009 19343178 Soranzo N 04/03/2009 PLoS Genet Height 7p15.1 7 28185091 JAZF1 JAZF1 rs849141-? rs849141 849141 intron 1 0.23 3E-11 .08 7 28182178 28182638 7 28185091 28185091 -0.78361633093 1.02063146075E-4 1.11002097214 -0.517140669489 0.185276349047 0.01330943 07/24/2012 22504420 Estrada K 04/15/2012 Nat Genet Bone mineral density 7p14.1 7 38128326 STARD3NL EPDR1 - STARD3NL rs6959212-T rs6959212 6959212 Intergenic 2 0.32 4E-38 .07 7 38110179 38110680 7 38128326 38128326 0.994804014922 7.79271491806E-9 -1.37164490113 0.70481549026 0.143037371953 4.17926E-6 10/16/2009 19801982 Rivadeneira F 10/04/2009 Nat Genet Bone mineral density (spine) 7p14.1 7 38136277 STARD3NL EPDR1 - STARD3NL rs1524058-T rs1524058 1524058 Intergenic 2 0.40 1E-9 .07 7 38110179 38110680 7 38136277 38136277 0.962223351276 9.75581920047E-9 -1.27032496958 0.701581912452 0.139617053987 5.070501E-6 11/17/2010 20935630 Speliotes EK 10/10/2010 Nat Genet Body mass index 7q11.23 7 76639871 KIAA1505 PMS2L11 rs6955651-T rs6955651 6955651 1 0.18 2E-6 NR 7 76614205 76614625 7 76639871 76639871 -0.608265126378 5.49454482566E-6 0.68114115908 -0.588820070438 0.119279438343 0.001192244 06/14/2009 19454037 Arnett DK 05/19/2009 BMC Med Genet Left ventricular mass 7q21.11 7 80258810 CD36 CD36 rs10499859-? rs10499859 10499859 intron 1 0.45 3E-6 .09 7 80288789 80289191 7 80258810 80258810 0.684402309224 3.29158451778E-5 -0.71850654259 0.546886643286 0.149674834458 0.00531238 11/25/2008 17903295 Lunetta KL 09/19/2007 BMC Med Genet Aging traits 7q21.11 7 82337859 Intergenic CACNA2D1 - PCLO rs2371208-? rs2371208 2371208 Intergenic 2 NR 3E-6 NR 7 82358734 82359145 7 82337859 82337859 -0.61967926719 3.92717546072E-4 0.265751316544 -0.477704849463 0.162802519621 0.0380199 01/21/2009 19122664 Silverberg MS 01/04/2009 Nat Genet Ulcerative colitis 7q31.1 7 107503441 SLC26A3, DLD, LAMB1 SLC26A3 - DLD rs4598195-? rs4598195 4598195 Intergenic 2 0.54 1E-6 1.23 7 107519785 107520265 7 107503441 107503441 0.512389862538 2.36585593813E-4 -0.466095417037 0.493103221164 0.129142542142 0.02565657 04/02/2010 20228799 McGovern DP 03/14/2010 Nat Genet Ulcerative colitis 7q31.1 7 107503441 DLD,LAMB1 SLC26A3 - DLD rs4598195-A rs4598195 4598195 Intergenic 2 NR 8E-8 1.09 7 107519785 107520265 7 107503441 107503441 0.512389862538 2.36585593813E-4 -0.466095417037 0.493103221164 0.129142542142 0.02565657 10/15/2009 19197348 Lowe JK 02/06/2009 PLoS Genet Quantitative traits 7q36.3 7 157090296 UBE3C RPL36AP30 - DNAJB6 rs2527866-C rs2527866 2527866 Intergenic 2 0.23 3E-6 .27 7 157091071 157091518 7 157090296 157090296 -1.04707743312 1.07705925535E-7 0.496247930517 -0.664137815736 0.168382808513 4.113762E-5 10/15/2009 19197348 Lowe JK 02/06/2009 PLoS Genet Quantitative traits 7q36.3 7 157090296 UBE3C RPL36AP30 - DNAJB6 rs2527866-C rs2527866 2527866 Intergenic 2 0.23 3E-6 .27 7 157092467 157092782 7 157090296 157090296 -0.814402262079 6.01313477514E-5 0.385979698987 -0.531394968905 0.185468677177 0.00869234 11/18/2011 22001757 Chambers JC 10/16/2011 Nat Genet Liver enzyme levels (alkaline phosphatase) 8p23.1 8 9178268 PPP1R3B PPP1R3B - TNKS rs6984305-A rs6984305 6984305 Intergenic 2 0.11 2E-10 2.70 8 9178038 9178461 8 9178268 9178268 1.09612085339 1.25674865589E-5 -1.90860863608 0.570149706492 0.225631972486 0.002392097 01/25/2012 20686565 Teslovich TM 08/05/2010 Nature Cholesterol, total 8p23.1 8 9183358 PPP1R3B PPP1R3B - TNKS rs9987289-T rs9987289 9987289 Intergenic 2 0.1 9E-24 3.14 8 9178038 9178461 8 9183358 9183358 1.18624055077 8.13534666618E-5 -2.20366700223 0.523329016776 0.27593457753 0.01112017 01/25/2012 20686565 Teslovich TM 08/05/2010 Nature HDL cholesterol 8p23.1 8 9183358 PPP1R3B PPP1R3B - TNKS rs9987289-A rs9987289 9987289 Intergenic 2 0.09 6E-25 1.21 8 9178038 9178461 8 9183358 9183358 1.18624055077 8.13534666618E-5 -2.20366700223 0.523329016776 0.27593457753 0.01112017 01/25/2012 20686565 Teslovich TM 08/05/2010 Nature LDL cholesterol 8p23.1 8 9183358 PPP1R3B PPP1R3B - TNKS rs9987289-T rs9987289 9987289 Intergenic 2 0.1 7E-15 2.22 8 9178038 9178461 8 9183358 9183358 1.18624055077 8.13534666618E-5 -2.20366700223 0.523329016776 0.27593457753 0.01112017 03/28/2011 21300955 Dehghan A 02/07/2011 Circulation C-reactive protein 8p23.1 8 9183358 PPP1R3B PPP1R3B - TNKS rs9987289-A rs9987289 9987289 Intergenic 2 NR 3E-13 .07 8 9178038 9178461 8 9183358 9183358 1.18624055077 8.13534666618E-5 -2.20366700223 0.523329016776 0.27593457753 0.01112017 04/11/2011 21386085 Kraja AT 03/08/2011 Diabetes HDL Cholesterol - Triglycerides (HDLC-TG) 8p23.1 8 9183358 LOC100129150 PPP1R3B - TNKS rs9987289-A rs9987289 9987289 Intergenic 2 NR 1E-8 .25 8 9178038 9178461 8 9183358 9183358 1.18624055077 8.13534666618E-5 -2.20366700223 0.523329016776 0.27593457753 0.01112017 04/11/2011 21386085 Kraja AT 03/08/2011 Diabetes Metabolic syndrome (bivariate traits) 8p23.1 8 9183358 LOC100129150 PPP1R3B - TNKS rs9987289-A rs9987289 9987289 Intergenic 2 NR 4E-8 .24 8 9178038 9178461 8 9183358 9183358 1.18624055077 8.13534666618E-5 -2.20366700223 0.523329016776 0.27593457753 0.01112017 04/07/2011 21347282 Lettre G 02/10/2011 PLoS Genet Coronary heart disease 8p23.1 8 9184691 PPP1R3B PPP1R3B - TNKS rs6601299-T rs6601299 6601299 Intergenic 2 0.16 1E-8 .14 8 9178038 9178461 8 9184691 9184691 1.17030425806 5.11745072756E-5 -2.15134708513 0.535616594708 0.26358850408 0.007610634 10/17/2010 20864672 Waterworth DM 09/23/2010 Arterioscler Thromb Vasc Biol LDL cholesterol 8p23.1 8 9185146 PPP1R3B PPP1R3B - TNKS rs2126259-A rs2126259 2126259 Intergenic 2 0.13 7E-12 .02 8 9178038 9178461 8 9185146 9185146 1.17030425806 5.11745072756E-5 -2.15134708513 0.535616594708 0.26358850408 0.007610634 04/07/2011 21408207 Chung SA 03/03/2011 PLoS Genet Systemic lupus erythematosus 8p23.1 8 11343973 BLK FAM167A - BLK rs2736340-T rs2736340 2736340 Intergenic 2 0.23 3E-7 1.38 8 11337593 11338011 8 11343973 11343973 -1.06601597894 2.29188041809E-13 0.623832945865 -0.818176190133 0.10701932256 4.642319E-10 04/25/2012 22446961 Lee YC 03/25/2012 Nat Genet Kawasaki disease 8p23.1 8 11343973 BLK FAM167A - BLK rs2736340-T rs2736340 2736340 Intergenic 2 0.722 9E-10 1.54 8 11337593 11338011 8 11343973 11343973 -1.06601597894 2.29188041809E-13 0.623832945865 -0.818176190133 0.10701932256 4.642319E-10 06/17/2009 19503088 Gregersen PK 06/07/2009 Nat Genet Rheumatoid arthritis 8p23.1 8 11343973 BLK FAM167A - BLK rs2736340-A rs2736340 2736340 Intergenic 2 0.24 6E-9 1.19 8 11337593 11338011 8 11343973 11343973 -1.06601597894 2.29188041809E-13 0.623832945865 -0.818176190133 0.10701932256 4.642319E-10 04/07/2011 21408207 Chung SA 03/03/2011 PLoS Genet Systemic lupus erythematosus 8p23.1 8 11343973 BLK FAM167A - BLK rs2736340-T rs2736340 2736340 Intergenic 2 0.23 3E-7 1.38 8 11339579 11339993 8 11343973 11343973 -0.969423004803 1.53199009434E-5 0.573846454407 -0.56550572378 0.20197500903 0.002828589 04/25/2012 22446961 Lee YC 03/25/2012 Nat Genet Kawasaki disease 8p23.1 8 11343973 BLK FAM167A - BLK rs2736340-T rs2736340 2736340 Intergenic 2 0.722 9E-10 1.54 8 11339579 11339993 8 11343973 11343973 -0.969423004803 1.53199009434E-5 0.573846454407 -0.56550572378 0.20197500903 0.002828589 06/17/2009 19503088 Gregersen PK 06/07/2009 Nat Genet Rheumatoid arthritis 8p23.1 8 11343973 BLK FAM167A - BLK rs2736340-A rs2736340 2736340 Intergenic 2 0.24 6E-9 1.19 8 11339579 11339993 8 11343973 11343973 -0.969423004803 1.53199009434E-5 0.573846454407 -0.56550572378 0.20197500903 0.002828589 04/07/2011 21408207 Chung SA 03/03/2011 PLoS Genet Systemic lupus erythematosus 8p23.1 8 11343973 BLK FAM167A - BLK rs2736340-T rs2736340 2736340 Intergenic 2 0.23 3E-7 1.38 8 11314716 11315114 8 11343973 11343973 0.680545678386 0.00146928493755 -0.395262582978 0.433860404983 0.2018944703 0.09935025 04/25/2012 22446961 Lee YC 03/25/2012 Nat Genet Kawasaki disease 8p23.1 8 11343973 BLK FAM167A - BLK rs2736340-T rs2736340 2736340 Intergenic 2 0.722 9E-10 1.54 8 11314716 11315114 8 11343973 11343973 0.680545678386 0.00146928493755 -0.395262582978 0.433860404983 0.2018944703 0.09935025 06/17/2009 19503088 Gregersen PK 06/07/2009 Nat Genet Rheumatoid arthritis 8p23.1 8 11343973 BLK FAM167A - BLK rs2736340-A rs2736340 2736340 Intergenic 2 0.24 6E-9 1.19 8 11314716 11315114 8 11343973 11343973 0.680545678386 0.00146928493755 -0.395262582978 0.433860404983 0.2018944703 0.09935025 11/25/2008 18204098 Hom G 01/20/2008 N Engl J Med Systemic lupus erythematosus 8p23.1 8 11349186 C8orf13, BLK FAM167A - BLK rs13277113-A rs13277113 13277113 Intergenic 2 0.23 1E-10 1.39 8 11337593 11338011 8 11349186 11349186 -1.06601597894 2.29188041809E-13 0.623832945865 -0.818176190133 0.10701932256 4.642319E-10 11/25/2008 18204098 Hom G 01/20/2008 N Engl J Med Systemic lupus erythematosus 8p23.1 8 11349186 C8orf13, BLK FAM167A - BLK rs13277113-A rs13277113 13277113 Intergenic 2 0.23 1E-10 1.39 8 11339579 11339993 8 11349186 11349186 -0.969423004803 1.53199009434E-5 0.573846454407 -0.56550572378 0.20197500903 0.002828589 11/25/2008 18204098 Hom G 01/20/2008 N Engl J Med Systemic lupus erythematosus 8p23.1 8 11349186 C8orf13, BLK FAM167A - BLK rs13277113-A rs13277113 13277113 Intergenic 2 0.23 1E-10 1.39 8 11314716 11315114 8 11349186 11349186 0.680545678386 0.00146928493755 -0.395262582978 0.433860404983 0.2018944703 0.09935025 11/25/2008 19165918 Graham RR 08/01/2008 Nat Genet Systemic lupus erythematosus 8p23.1 8 11352541 BLK BLK rs2618476-? rs2618476 2618476 intron 1 0.26 2E-8 1.29 8 11337593 11338011 8 11352541 11352541 -1.06601597894 2.29188041809E-13 0.623832945865 -0.818176190133 0.10701932256 4.642319E-10 11/25/2008 19165918 Graham RR 08/01/2008 Nat Genet Systemic lupus erythematosus 8p23.1 8 11352541 BLK BLK rs2618476-? rs2618476 2618476 intron 1 0.26 2E-8 1.29 8 11339579 11339993 8 11352541 11352541 -0.969423004803 1.53199009434E-5 0.573846454407 -0.56550572378 0.20197500903 0.002828589 11/25/2008 19165918 Graham RR 08/01/2008 Nat Genet Systemic lupus erythematosus 8p23.1 8 11352541 BLK BLK rs2618476-? rs2618476 2618476 intron 1 0.26 2E-8 1.29 8 11314716 11315114 8 11352541 11352541 0.680545678386 0.00146928493755 -0.395262582978 0.433860404983 0.2018944703 0.09935025 02/16/2011 21452313 Freudenberg J 01/10/2011 Arthritis Rheum Rheumatoid arthritis 8p23.1 8 11359638 BLK BLK rs1600249-? rs1600249 1600249 intron 1 0.67 5E-6 1.30 8 11337593 11338011 8 11359638 11359638 -0.574122055448 2.16464540796E-4 0.155979172142 -0.495730529676 0.143687352282 0.02396007 04/29/2011 21452313 Freudenberg J 04/01/2011 Arthritis Rheum Rheumatoid arthritis 8p23.1 8 11359638 BLK BLK rs1600249-? rs1600249 1600249 intron 1 0.67 5E-6 1.30 8 11337593 11338011 8 11359638 11359638 -0.574122055448 2.16464540796E-4 0.155979172142 -0.495730529676 0.143687352282 0.02396007 02/16/2011 21452313 Freudenberg J 01/10/2011 Arthritis Rheum Rheumatoid arthritis 8p23.1 8 11359638 BLK BLK rs1600249-? rs1600249 1600249 intron 1 0.67 5E-6 1.30 8 11314716 11315114 8 11359638 11359638 0.655547913133 4.98946510896E-4 -0.187259653177 0.470170621163 0.175793494219 0.04550011 04/29/2011 21452313 Freudenberg J 04/01/2011 Arthritis Rheum Rheumatoid arthritis 8p23.1 8 11359638 BLK BLK rs1600249-? rs1600249 1600249 intron 1 0.67 5E-6 1.30 8 11314716 11315114 8 11359638 11359638 0.655547913133 4.98946510896E-4 -0.187259653177 0.470170621163 0.175793494219 0.04550011 04/20/2012 22451204 Pankratz N 03/01/2012 Ann Neurol Parkinson's disease 8p23.1 8 11698747 Intergenic FDFT1 - CTSB rs1296028-? rs1296028 1296028 Intergenic 2 NR 1E-6 1.15 8 11702978 11703517 8 11698747 11698747 0.658192588438 1.20500745516E-5 -0.233944809085 0.571126603268 0.135142734533 0.002310742 02/09/2012 22267200 Gudmundsson J 01/22/2012 Nat Genet Thyroid cancer 8p12 8 32432369 NRG1 NRG1 rs2439302-G rs2439302 2439302 intron 1 0.351 2E-9 1.36 8 32412164 32412604 8 32432369 32432369 0.310325410278 8.60033701848E-4 -0.366704245401 0.452364782405 0.0874005268826 0.06804691 11/25/2008 18455228 Richards JB 04/29/2008 Lancet Bone mineral density 8q24.12 8 119923873 TNFRSF11B RPS26P35 - TNFRSF11B rs4355801-A rs4355801 4355801 Intergenic 2 0.53 8E-10 .09 8 119960800 119961317 8 119923873 119923873 0.539517640867 1.60985943194E-4 -0.534853091749 0.504332962571 0.131964543801 0.01904316 07/04/2010 20548944 Hsu YH 06/10/2010 PLoS Genet Osteoporosis 8q24.12 8 119977792 TNFRSF11B TNFRSF11B - COLEC10 rs2062375-G rs2062375 2062375 Intergenic 2 0.45 3E-11 .14 8 119960800 119961317 8 119977792 119977792 -0.529272493026 8.63447576473E-5 0.54391316366 -0.521715774272 0.123639464631 0.01160968 07/24/2012 22504420 Estrada K 04/15/2012 Nat Genet Bone mineral density 8q24.12 8 120007420 TNFRSF11B TNFRSF11B - COLEC10 rs2062377-A rs2062377 2062377 Intergenic 2 0.57 3E-39 .08 8 119960800 119961317 8 120007420 120007420 -0.45943016466 0.00104575522595 0.460954028437 -0.445728575713 0.131812202089 0.07853428 10/16/2009 19801982 Rivadeneira F 10/04/2009 Nat Genet Bone mineral density (spine) 8q24.12 8 120007420 TNFRSF11B TNFRSF11B - COLEC10 rs2062377-T rs2062377 2062377 Intergenic 2 0.44 4E-16 .09 8 119960800 119961317 8 120007420 120007420 -0.45943016466 0.00104575522595 0.460954028437 -0.445728575713 0.131812202089 0.07853428 02/24/2012 21886157 Suhre K 08/31/2011 Nature Metabolic traits 8q24.3 8 145139522 OPLAH GPAA1 rs6558295-G rs6558295 6558295 intron 1 0.083 2E-59 .12 8 145163117 145163499 8 145139522 145139522 0.359232638164 2.00329398564E-5 -0.0210946994315 0.559102153414 0.0761014369575 0.003517496 04/22/2009 19343178 Soranzo N 04/03/2009 PLoS Genet Height 9p13.3 9 34071541 WDR40A RNU7-36P - DCAF12 rs7871764-? rs7871764 7871764 Intergenic 2 0.44 2E-6 .06 9 34074167 34074636 9 34071541 34071541 0.466740212935 1.2949935255E-4 -0.702975155734 0.510513085975 0.112306033832 0.01605952 01/24/2012 21254220 Jiang Y 02/01/2011 Genet Epidemiol Bipolar disorder 9q32 9 117260834 NR DFNB31 rs10982256-? rs10982256 10982256 intron 1 NR 9E-6 NR 9 117249827 117250252 9 117260834 117260834 0.396435234387 0.00110800410685 -0.435056289379 0.443740281235 0.114374364836 0.0817472 11/25/2008 18711365 Ferreira MA 08/17/2008 Nat Genet Bipolar disorder 9q33.3 9 130107964 NR GARNL3 rs4130590-? rs4130590 4130590 intron 1 0.56 3E-6 1.16 9 130110353 130110762 9 130107964 130107964 -0.748535424001 3.72674128315E-4 0.843375066972 -0.479330624205 0.195791026049 0.03649428 05/07/2009 18839057 Lesch KP 10/07/2008 J Neural Transm Attention deficit hyperactivity disorder 9q34.11 9 130976557 DNM1 DNM1 rs2502731-? rs2502731 2502731 intron 1 NR 2E-6 NR 9 130953709 130954147 9 130976557 130976557 -0.635834121952 5.57817347146E-4 0.906148728581 -0.466600761722 0.172179917661 0.04960398 05/07/2009 18839057 Lesch KP 10/07/2008 J Neural Transm Attention deficit hyperactivity disorder 9q34.11 9 130976557 DNM1 DNM1 rs2502731-? rs2502731 2502731 intron 1 NR 2E-6 NR 9 130955037 130955425 9 130976557 130976557 -0.97838227287 9.32642081782E-6 1.4090407937 -0.577013540507 0.197836069089 0.001861501 09/22/2010 20709820 Kong X 08/13/2010 Am J Respir Crit Care Med Emphysema-related traits 10q11.21 10 45319654 AL139 119.2 RPL9P21 - TMEM72 rs7911712-A rs7911712 7911712 Intergenic 2 0.15 6E-6 2.05 10 45348599 45349003 10 45319654 45319654 0.992155584645 6.81647770931E-4 -0.217964499041 0.460084863963 0.273524098997 0.05776357 07/01/2009 19553259 Cotsapas C 06/24/2009 Hum Mol Genet Obesity (extreme) 10q22.1 10 72332440 PRF1 KIAA1274 - PRF1 rs10999409-T rs10999409 10999409 Intergenic 2 0.45 5E-6 1.30 10 72318962 72319490 10 72332440 72332440 0.619447279147 2.49009016522E-4 -0.76552044239 0.491580735774 0.156763819415 0.0267484 10/16/2010 20881960 Lango Allen H 09/29/2010 Nature Height 10q22.3 10 81121696 PPIF PPIF - ZCCHC24 rs2145998-A rs2145998 2145998 Intergenic 2 0.49 4E-13 .03 10 81106567 81107672 10 81121696 81121696 0.367989574909 5.6815729241E-5 -0.291778082623 0.532885932488 0.0834775342415 0.008294546 11/08/2011 21998595 N'Diaye A 10/06/2011 PLoS Genet Height 10q22.3 10 81139462 Intergenic PPIF - ZCCHC24 rs941873-A rs941873 941873 Intergenic 2 0.41 4E-7 .04 10 81106567 81107672 10 81139462 81139462 0.325705238662 3.22203044125E-4 -0.260854751398 0.483804908506 0.084168923085 0.03269591 11/25/2008 17903301 Vasan RS 09/19/2007 BMC Med Genet Endothelial function traits 10q24.33 10 105647095 OBFC1 OBFC1 rs3814219-? rs3814219 3814219 intron 1 NR 9E-7 NR 10 105648043 105648433 10 105647095 105647095 -0.37636734225 0.00136421799614 0.224881242461 -0.436486539208 0.110827098876 0.0944471 02/23/2012 22286173 Low SK 01/27/2012 Hum Mol Genet Intracranial aneurysm 11p15.5 11 203788 BET1L BET1L rs2280543-T rs2280543 2280543 UTR-3 1 0.124 3E-6 1.25 11 189721 190344 11 203788 203788 0.944576385363 1.03152762129E-5 -0.118240903524 0.574711669154 0.192145972049 0.002023136 05/02/2011 21460842 Cha PC 04/03/2011 Nat Genet Uterine fibroids 11p15.5 11 203788 ODF3, BET1L, RIC8A, SIRT3 BET1L rs2280543-G rs2280543 2280543 UTR-3 1 0.88 4E-12 1.39 11 189721 190344 11 203788 203788 0.944576385363 1.03152762129E-5 -0.118240903524 0.574711669154 0.192145972049 0.002023136 07/01/2009 19557197 Heard-Costa NL 06/26/2009 PLoS Genet Waist circumference 11p15.4 11 7708281 OVCH2 CYB5R2 - OVCH2 rs7932813-? rs7932813 7932813 Intergenic 2 NR 5E-6 NR 11 7711885 7712256 11 7708281 7708281 0.941678076651 1.40548957244E-5 -0.248796603642 0.56753530456 0.195162122198 0.002632242 07/01/2010 20541252 Wang TJ 06/09/2010 Lancet Vitamin D insufficiency 11p15.2 11 14914878 CYP2R1 CYP2R1 rs10741657-? rs10741657 10741657 nearGene-5 1 0.40 3E-20 NR 11 14928787 14930479 11 14914878 14914878 -0.525766014693 7.45099069806E-5 0.580516960223 -0.52569493117 0.121541170692 0.01035646 01/07/2011 21124955 Marzi C 11/18/2010 PLoS Genet Amyloid A Levels 11p15.1 11 18323517 HPS5, GTF2H1 HPS5 rs4353250-T rs4353250 4353250 intron 1 0.35 2E-51 .27 11 18289267 18289657 11 18323517 18323517 -0.723075284712 5.48718634732E-6 1.03958536836 -0.588849394869 0.141782646146 0.001190732 02/24/2012 21886157 Suhre K 08/31/2011 Nature Metabolic traits 11p15.1 11 18325146 HPS5 HPS5 rs2403254-T rs2403254 2403254 intron 1 0.525 1E-20 .11 11 18289267 18289657 11 18325146 18325146 -0.673826646972 8.5883151327E-5 0.838900667397 -0.521861338057 0.157347371005 0.0115684 09/27/2011 21873549 Strawbridge RJ 08/26/2011 Diabetes Proinsulin levels 11p11.2 11 47312892 MADD MADD rs10838687-T rs10838687 10838687 intron 1 0.80 7E-12 NR 11 47279404 47279840 11 47312892 47312892 0.713140512648 0.00139102426928 -0.191467056204 0.435799795779 0.210403814763 0.09576858 04/03/2012 22412388 Kenny EE 03/08/2012 PLoS Genet Crohn's disease 11q12.1 11 57203009 SLC43A3, PRG2, PRG3 SLC43A3 - RTN4RL2 rs11229030-C rs11229030 11229030 Intergenic 2 0.305 8E-9 1.15 11 57198420 57198827 11 57203009 57203009 -0.62631782001 0.00113226125884 0.892144403496 -0.442992490567 0.181076847423 0.0830472 06/23/2011 21627779 Antunez C 05/31/2011 Genome Med Alzheimer's disease 11q12.2 11 60023087 MS4A MS4A4E - MS4A4A rs1562990-? rs1562990 1562990 Intergenic 2 0.58 4E-11 1.14 11 60018960 60019402 11 60023087 60023087 -1.12807663844 5.10539079024E-14 1.18647649466 -0.829996546311 0.108297464128 1.375491E-10 05/24/2011 21460841 Naj AC 04/03/2011 Nat Genet Alzheimer's disease (late onset) 11q12.2 11 60034429 MS4A4A MS4A4E - MS4A4A rs4938933-? rs4938933 4938933 Intergenic 2 0.61 8E-12 1.12 11 60018960 60019402 11 60034429 60034429 -1.11353162162 1.69188250115E-13 1.12769317829 -0.820636874847 0.110772443309 3.594989E-10 09/01/2011 21829377 Lemaitre RN 07/28/2011 PLoS Genet Phospholipid levels (plasma) 11q12.2 11 61417472 DAGLA RPLP0P2 - DAGLA rs1692120-A rs1692120 1692120 Intergenic 2 NR 1E-8 .01 11 61427280 61427618 11 61417472 61417472 0.567170374851 7.83586558147E-6 -0.455277487458 0.580950556106 0.113518881807 0.00160381 07/01/2010 20541252 Wang TJ 06/09/2010 Lancet Vitamin D insufficiency 11q13.4 11 71167449 DHCR7,NADSYN1 NADSYN1 rs12785878-? rs12785878 12785878 intron 1 0.23 2E-27 NR 11 71164265 71164594 11 71167449 71167449 0.576895986074 9.56409947216E-4 -0.832489805727 0.448776305666 0.164109666952 0.07343263 11/25/2008 17553421 Reiman EM 06/07/2007 Neuron Alzheimer's disease (late onset) 11q14.1 11 78091150 GAB2 GAB2 rs2373115-G rs2373115 2373115 intron 1 0.70 1E-10 4.06 11 78131309 78131760 11 78091150 78091150 0.609632688393 6.77267444077E-4 -0.179473602561 0.460296412086 0.167969634717 0.05747984 01/08/2011 21102462 Elks CE 11/21/2010 Nat Genet Menarche (age at onset) 11q14.1 11 78095373 GAB2 GAB2 rs10899489-A rs10899489 10899489 intron 1 0.15 8E-9 3.10 11 78131309 78131760 11 78095373 78095373 0.609632688393 6.77267444077E-4 -0.179473602561 0.460296412086 0.167969634717 0.05747984 07/21/2012 22566498 Turner ST 05/07/2012 Hypertension Response to angiotensin II receptor blocker therapy 11q21 11 94271663 FUT4 ANKRD49 - FUT4 rs11020821-C rs11020821 11020821 Intergenic 2 NR 9E-7 1.40 11 94234754 94235145 11 94271663 94271663 -1.05526710079 2.83214773284E-6 0.665075227854 -0.602980370878 0.199448730306 6.846358E-4 07/21/2012 22566498 Turner ST 05/07/2012 Hypertension Response to angiotensin II receptor blocker therapy (opposite direction w/ diuretic therapy) 11q21 11 94271663 FUT4 ANKRD49 - FUT4 rs11020821-C rs11020821 11020821 Intergenic 2 NR 4E-6 NR 11 94234754 94235145 11 94271663 94271663 -1.05526710079 2.83214773284E-6 0.665075227854 -0.602980370878 0.199448730306 6.846358E-4 12/09/2008 18846501 Sonuga-Barke EJ 10/07/2008 Am J Med Genet B Neuropsychiatr Genet Attention deficit hyperactivity disorder symptoms (interaction) 11q21 11 94312323 PIWIL4 PIWIL4 rs2212361-C rs2212361 2212361 intron 1 0.26 9E-7 .97 11 94336248 94336644 11 94312323 94312323 1.09922282454 9.88939653779E-10 -0.767725671865 0.732631518205 0.145884889062 6.893197E-7 07/11/2012 22561518 Jin Y 05/06/2012 Nat Genet Vitiligo 11q21 11 95311422 TYR SESN3 - FAM76B rs4409785-C rs4409785 4409785 Intergenic 2 0.19 2E-13 1.34 11 95311198 95311593 11 95311422 95311422 1.10417720127 8.30066412093E-8 -0.263018517854 0.668472007586 0.17549998115 3.265701E-5 09/24/2011 21833088 Sawcer S 08/11/2011 Nature Multiple sclerosis 11q21 11 95311422 NA SESN3 - FAM76B rs4409785-G rs4409785 4409785 Intergenic 2 NR 6E-7 1.10 11 95311198 95311593 11 95311422 95311422 1.10417720127 8.30066412093E-8 -0.263018517854 0.668472007586 0.17549998115 3.265701E-5 12/09/2010 21118971 Wu C 11/30/2010 Cancer Res Small-cell lung cancer 11q22.3 11 103418158 DYNC2H1 DYNC2H1 - PDGFD rs716274-G rs716274 716274 Intergenic 2 NR 9E-8 1.83 11 103408608 103409069 11 103418158 103418158 0.553005723506 0.00101934601866 -0.623679406767 0.446604330222 0.158271025091 0.07710267 01/15/2011 21149283 Oexle K 12/10/2010 Hum Mol Genet Iron status biomarkers 11q23.3 11 117091609 PCSK7 PCSK7 rs236918-C rs236918 236918 intron 1 NR 1E-27 .04 11 117051957 117052367 11 117091609 117091609 0.540146562371 5.26278182275E-5 -0.179391641338 0.534887652779 0.121890044115 0.007787647 11/25/2008 17903295 Lunetta KL 09/19/2007 BMC Med Genet Aging traits 12p11.22 12 30113883 Intergenic RPL21P99 - IPO8 rs1463605-? rs1463605 1463605 Intergenic 2 NR 7E-8 NR 12 30129711 30129807 12 30113883 30113883 -0.711104646326 7.96826709783E-4 0.112581256504 -0.454919864335 0.198861307123 0.06453747 08/12/2010 20596022 Petukhova L 07/01/2010 Nature Alopecia areata 12q13.2 12 56412487 IKZF4 SUOX - IKZF4 rs1701704-C rs1701704 1701704 Intergenic 2 0.33 3E-8 1.34 12 56435260 56435640 12 56412487 56412487 -0.686256441897 2.71878720235E-6 0.436606708528 -0.603831424246 0.129417216536 6.612954E-4 08/27/2011 21804548 Hirota T 07/31/2011 Nat Genet Asthma 12q13.2 12 56412487 IKZF4 SUOX - IKZF4 rs1701704-G rs1701704 1701704 Intergenic 2 0.18 2E-13 1.19 12 56435260 56435640 12 56412487 56412487 -0.686256441897 2.71878720235E-6 0.436606708528 -0.603831424246 0.129417216536 6.612954E-4 09/21/2011 21829393 Plagnol V 08/04/2011 PLoS Genet Type 1 diabetes autoantibodies 12q13.2 12 56412487 IKZF4 SUOX - IKZF4 rs1701704-T rs1701704 1701704 Intergenic 2 NR 5E-18 1.25 12 56435260 56435640 12 56412487 56412487 -0.686256441897 2.71878720235E-6 0.436606708528 -0.603831424246 0.129417216536 6.612954E-4 11/25/2008 18198356 Hakonarson H 01/15/2008 Diabetes Type 1 diabetes 12q13.2 12 56412487 RAB5B, SUOX, IKZF4, ERBB3, CDK2 SUOX - IKZF4 rs1701704-C rs1701704 1701704 Intergenic 2 0.35 9E-10 1.25 12 56435260 56435640 12 56412487 56412487 -0.686256441897 2.71878720235E-6 0.436606708528 -0.603831424246 0.129417216536 6.612954E-4 07/11/2012 22561518 Jin Y 05/06/2012 Nat Genet Vitiligo 12q13.2 12 56416928 IKZF4 IKZF4 rs2456973-C rs2456973 2456973 intron 1 0.35 3E-14 1.29 12 56435260 56435640 12 56416928 56416928 -0.702568734932 4.35247877659E-7 0.461257428099 -0.639630742451 0.120616950468 1.372144E-4 11/25/2008 17554300 WTCCC 06/07/2007 Nature Type 1 diabetes 12q13.2 12 56470625 ERBB3 RPS26 - ERBB3 rs11171739-C rs11171739 11171739 Intergenic 2 0.42 1E-11 1.34 12 56435260 56435640 12 56470625 56470625 0.737463419949 4.11550745834E-7 -0.874041542481 0.640656553964 0.126264386445 1.307372E-4 06/01/2009 19430480 Barrett JC 05/10/2009 Nat Genet Type 1 diabetes 12q13.2 12 56482180 ERBB3 ERBB3 rs2292239-? rs2292239 2292239 intron 1 NR 2E-25 NR 12 56435260 56435640 12 56482180 56482180 0.760326042634 8.03677112322E-8 -1.03466564292 0.669004659463 0.120673635912 3.173651E-5 09/21/2011 21829393 Plagnol V 08/04/2011 PLoS Genet Type 1 diabetes autoantibodies 12q13.2 12 56482180 ERBB3 ERBB3 rs2292239-T rs2292239 2292239 intron 1 NR 3E-27 1.30 12 56435260 56435640 12 56482180 56482180 0.760326042634 8.03677112322E-8 -1.03466564292 0.669004659463 0.120673635912 3.173651E-5 11/25/2008 17554260 Todd JA 06/06/2007 Nat Genet Type 1 diabetes 12q13.2 12 56482180 ERBB3 ERBB3 rs2292239-A rs2292239 2292239 intron 1 0.34 2E-20 1.28 12 56435260 56435640 12 56482180 56482180 0.760326042634 8.03677112322E-8 -1.03466564292 0.669004659463 0.120673635912 3.173651E-5 11/25/2008 18978792 Cooper JD 11/02/2008 Nat Genet Type 1 diabetes 12q13.2 12 56482180 ERBB3 ERBB3 rs2292239-A rs2292239 2292239 intron 1 NR 3E-16 NR 12 56435260 56435640 12 56482180 56482180 0.760326042634 8.03677112322E-8 -1.03466564292 0.669004659463 0.120673635912 3.173651E-5 04/27/2012 22424883 Imboden M 03/15/2012 J Allergy Clin Immunol Pulmonary function decline 12q14.1 12 62610860 USP15 RPS3P6 - USP15 rs11615916-? rs11615916 11615916 Intergenic 2 NR 7E-6 .24 12 62604069 62604529 12 62610860 62610860 -0.62040350941 0.00124399852757 0.170260890994 -0.439722978119 0.181024734391 0.08866626 05/18/2010 20395239 Macgregor S 04/15/2010 Hum Mol Genet Optic disc size (cup) 12q21.33 12 90443482 LOC643153 MRPL2P1 - C12orf12 rs10858945-A rs10858945 10858945 Intergenic 2 NR 6E-6 .17 12 90456729 90457056 12 90443482 90443482 -0.603585848373 2.01738655187E-4 0.64314799977 -0.497798091885 0.150228937928 0.02263524 06/02/2012 22504421 Bis JC 04/15/2012 Nat Genet Hippocampal volume 12q24.22 12 117327592 HRK HRK - RPL36P15 rs7294919-T rs7294919 7294919 Intergenic 2 0.91 3E-11 107.80 12 117354635 117355024 12 117327592 117327592 1.21107410187 1.23598816296E-5 -0.224738623507 0.570537127106 0.249043770196 0.002359719 06/21/2012 22504417 Stein JL 04/15/2012 Nat Genet Brain structure 12q24.22 12 117327592 HRK, FBXW8 HRK - RPL36P15 rs7294919-C rs7294919 7294919 Intergenic 2 0.099 7E-16 47.58 12 117354635 117355024 12 117327592 117327592 1.21107410187 1.23598816296E-5 -0.224738623507 0.570537127106 0.249043770196 0.002359719 06/17/2011 21640322 Shi Y 06/02/2011 Am J Hum Genet Myopia (pathological) 13q12.12 13 24432467 MIPEP, C1QTNF9B-AS1, C1QTNF9B MIPEP rs9318086-A rs9318086 9318086 intron 1 0.44 2E-16 1.32 13 24473687 24474085 13 24432467 24432467 0.918018127372 1.26567172941E-8 -1.05967671864 0.69778107465 0.134628095838 6.373884E-6 09/24/2010 20708005 Chalasani N 08/10/2010 Gastroenterology Non-alcoholic fatty liver disease histology (other) 13q12.3 13 29278450 SLC46A3 SLC46A3 rs1305088-A rs1305088 1305088 intron 1 0.06 9E-6 .58 13 29252925 29253413 13 29278450 29278450 -0.948659905535 1.4401942855E-4 1.71232438173 -0.507510159598 0.230089355155 0.0174382 09/24/2011 21833088 Sawcer S 08/11/2011 Nature Multiple sclerosis 14q24.3 14 76005557 BATF BATF rs2300603-A rs2300603 2300603 intron 1 NR 2E-8 1.11 14 75981674 75982106 14 76005557 76005557 -0.696189148904 0.00147249171727 0.41576177963 -0.433782921429 0.206580794993 0.09946893 09/21/2011 21841780 Chu X 08/14/2011 Nat Genet Graves' disease 14q31.1 14 81451229 TSHR TSHR rs12101261-T rs12101261 12101261 intron 1 0.64 7E-24 1.35 14 81453763 81454160 14 81451229 81451229 0.333432677387 0.00105165515785 -0.228694335856 0.445535640474 0.0957147541834 0.07884385 10/15/2010 20876420 Ingle JN 09/27/2010 J Clin Oncol Adverse response to aromatase inhibitors 14q32.13 14 96169131 TCL1A TCL1B - TCL1A rs7158782-? rs7158782 7158782 Intergenic 2 0.11 8E-7 2.13 14 96180335 96180707 14 96169131 96169131 -0.514328369996 1.95993483661E-4 0.129182736781 -0.498642166976 0.127725118846 0.02215079 01/11/2011 21172079 Ingle JN 12/20/2010 Breast Cancer Res Adverse response to aromatase inhibitors 14q32.13 14 96175978 TCL1A TCL1A rs11849538-? rs11849538 11849538 nearGene-3 1 NR 7E-7 NR 14 96180335 96180707 14 96175978 96175978 -0.514328369996 1.95993483661E-4 0.129182736781 -0.498642166976 0.127725118846 0.02215079 04/27/2012 22446963 Okada Y 03/25/2012 Nat Genet Rheumatoid arthritis 14q32.33 14 105391005 PLD4 PLD4 rs2841277-T rs2841277 2841277 nearGene-5 1 0.69 2E-14 1.15 14 105399694 105400115 14 105391005 105391005 0.752541580466 3.76857443963E-5 -0.785391320222 0.543473194521 0.166049288793 0.005943012 03/18/2011 21326860 Tsai FJ 02/04/2011 PLoS One Kawasaki disease 14q32.33 14 107176213 IGHV IGHV1-69 - IGHV2-70 rs10129255-A rs10129255 10129255 Intergenic 2 0.34 7E-6 1.32 14 107167649 107168147 14 107176213 107176213 -0.735113694374 2.12146188801E-4 0.362776423587 -0.4963232381 0.183687892397 0.02357302 11/25/2008 18483556 Han J 05/16/2008 PLoS Genet Black vs. blond hair color 15q13.1 15 29006093 Intergenic WHAMML2 - GOLGA6L7P rs8033165-T rs8033165 8033165 Intergenic 2 NR 5E-11 .12 15 29034676 29035129 15 29006093 29006093 0.741256788383 1.40363771181E-5 -0.522957457972 0.567566250412 0.153612594292 0.002629864 11/25/2008 18483556 Han J 05/16/2008 PLoS Genet Black vs. red hair color 15q13.1 15 29006093 Intergenic WHAMML2 - GOLGA6L7P rs8033165-T rs8033165 8033165 Intergenic 2 NR 2E-12 .15 15 29034676 29035129 15 29006093 29006093 0.741256788383 1.40363771181E-5 -0.522957457972 0.567566250412 0.153612594292 0.002629864 05/07/2009 18821565 Lasky-Su J 12/05/2008 Am J Med Genet B Neuropsychiatr Genet Inattentive symptoms 15q13.1 15 29888396 Intergenic NDNL2 - TJP1 rs1471225-? rs1471225 1471225 Intergenic 2 NR 8E-6 NR 15 29888392 29888906 15 29888396 29888396 0.60531918703 9.2477563698E-4 -0.647464076193 0.449916904454 0.171648414122 0.07176435 05/26/2011 21533175 Zhai G 04/14/2011 PLoS Genet Dehydroepiandrosterone sulphate levels 15q15.1 15 40360741 BMF SRP14 - BMF rs7181230-G rs7181230 7181230 Intergenic 2 0.33 5E-11 .05 15 40396445 40397425 15 40360741 40360741 0.321843577191 8.63359516535E-4 -0.211607688841 0.452235065622 0.09067720932 0.06822014 09/28/2010 20818381 Yamauchi T 09/05/2010 Nat Genet Type 2 diabetes 15q22.2 15 62396389 C2CD4A,C2CD4B C2CD4A - C2CD4B rs7172432-? rs7172432 7172432 Intergenic 2 0.58 9E-14 1.11 15 62434961 62435269 15 62396389 62396389 0.552586212584 2.30874953479E-4 -0.374545039898 0.493827580022 0.139003629116 0.02523925 10/12/2010 20862305 Shu XO 09/16/2010 PLoS Genet Type 2 diabetes 15q22.2 15 62404382 C2CD4B C2CD4A - C2CD4B rs1436955-C rs1436955 1436955 Intergenic 2 0.73 7E-7 1.13 15 62417944 62418368 15 62404382 62404382 -0.705203374283 1.20680976588E-4 0.305534338283 -0.51249058309 0.168798388504 0.01520463 02/23/2011 21239051 Reilly MP 01/14/2011 Lancet Coronary heart disease 15q25.1 15 79080234 ADAMTS7 ADAMTS7 rs1994016-C rs1994016 1994016 intron 1 0.60 5E-13 1.19 15 79032771 79033211 15 79080234 79080234 0.579335415223 5.65907277013E-4 -0.481349409826 0.46613706186 0.157079885456 0.05011838 07/12/2010 20581827 Voight BF 06/27/2010 Nat Genet Type 2 diabetes 15q25.1 15 80432222 ZFAND6 ZFAND6 - FAH rs11634397-G rs11634397 11634397 Intergenic 2 NR 2E-9 1.06 15 80383145 80383631 15 80432222 80432222 -0.625538885126 4.38922560095E-4 0.775505489516 -0.474225847853 0.165902403036 0.04134244 01/21/2010 20062064 Crowther-Swanepoel D 01/10/2010 Nat Genet Chronic lymphocytic leukemia 15q25.2 15 83254708 CPEB1 CPEB1 rs783540-G rs783540 783540 intron 1 NR 4E-6 1.18 15 83290688 83291203 15 83254708 83254708 0.502083024598 3.3755253917E-4 -0.365837217034 0.482380641585 0.130248505805 0.03385264 09/23/2010 20719862 Vitart V 08/18/2010 Hum Mol Genet Central corneal thickness 15q25.3 15 85825567 PDE8A,AKAP13 DNM1P45 - AKAP13 rs6496932-C rs6496932 6496932 Intergenic 2 0.22 1E-8 .13 15 85827001 85827446 15 85825567 85825567 -0.606327671481 0.00103528245133 0.303192638891 -0.446073464448 0.173789775959 0.07795341 07/24/2012 22504420 Estrada K 04/15/2012 Nat Genet Bone mineral density 16p13.3 16 375782 AXIN1 AXIN1 rs9921222-T rs9921222 9921222 intron 1 0.48 1E-16 .04 16 375137 375533 16 375782 375782 -0.543899083745 0.00119588623898 0.497191113697 -0.441097169045 0.158088691172 0.08626648 11/25/2008 18391950 Lettre G 04/06/2008 Nat Genet Height 16p13.3 16 675680 RAB40C RAB40C rs763014-C rs763014 763014 intron 1 0.43 5E-6 .24 16 628992 629441 16 675680 675680 -0.642918477972 5.30135914105E-5 0.525361181265 -0.534697263121 0.145154020525 0.007836175 10/16/2010 20881960 Lango Allen H 09/29/2010 Nature Height 16p13.3 16 792190 NARFL NARFL rs11648796-A rs11648796 11648796 nearGene-5 1 0.74 1E-13 .03 16 783594 784174 16 792190 792190 -0.884517694114 1.2309765508E-6 0.518153625431 -0.61986691571 0.159962259569 3.362993E-4 01/31/2012 22174851 Lingappa JR 12/12/2011 PLoS One HIV-1 susceptibility 16p13.3 16 3124920 IL32 IL32 - ZSCAN10 rs4349147-? rs4349147 4349147 Intergenic 2 NR 8E-6 .00 16 3122905 3123332 16 3124920 3124920 -0.671706774064 8.27668349168E-4 0.926286956285 -0.45365121798 0.188505794578 0.06630906 12/10/2009 19915574 Imielinski M 11/15/2009 Nat Genet Inflammatory bowel disease (early onset) 16p11.2 16 28837515 IL27, CCDC101, CLN3, EIF3C, NUPR1, SULT1A1, SULT1A2 ATXN2L rs8049439-G rs8049439 8049439 intron 1 0.37 2E-9 1.14 16 28813517 28814192 16 28837515 28837515 -0.527257182292 5.39778830668E-4 0.382700779836 -0.467656942889 0.14236562922 0.0483464 03/30/2009 19300499 Takeuchi F 03/20/2009 PLoS Genet Warfarin maintenance dose 16p11.2 16 31107689 VKORC1 VKORC1 rs9923231-T rs9923231 9923231 nearGene-5 1 0.40 3E-181 .97 16 31116920 31117307 16 31107689 31107689 -0.398785034152 7.38172454729E-4 0.340489459898 -0.457459463193 0.110739493814 0.06116141 10/05/2010 20833655 Cha PC 09/10/2010 Hum Mol Genet Warfarin maintenance dose 16p11.2 16 31107689 VKORC1 VKORC1 rs9923231-? rs9923231 9923231 nearGene-5 1 NR 9E-31 NR 16 31116920 31117307 16 31107689 31107689 -0.398785034152 7.38172454729E-4 0.340489459898 -0.457459463193 0.110739493814 0.06116141 05/07/2009 18839057 Lesch KP 10/07/2008 J Neural Transm Attention deficit hyperactivity disorder 16q23.3 16 82746937 CDH13 CDH13 rs11646411-? rs11646411 11646411 intron 1 NR 7E-6 NR 16 82772300 82772717 16 82746937 82746937 1.2179699575 1.45732054138E-5 -0.262017032562 0.566684101857 0.252982533288 0.002712569 07/11/2012 22561518 Jin Y 05/06/2012 Nat Genet Vitiligo 16q24.3 16 89818089 MC1R FANCA rs9926296-A rs9926296 9926296 intron 1 0.54 2E-13 1.27 16 89772283 89772715 16 89818089 89818089 -0.507730615006 0.0012690975776 0.567049238415 -0.439024863013 0.148440411818 0.0898441 11/25/2008 18464913 Melzer D 05/09/2008 PLoS Genet Protein quantitative trait loci 17q12 17 34819191 CCL4L2 TBC1D3G - ZNHIT3 rs4796217-? rs4796217 4796217 Intergenic 2 0.34 4E-21 NR 17 34797391 34797896 17 34819191 34819191 -0.307302366581 2.38304758786E-5 0.523705356885 -0.554886234674 0.0658186144385 0.004073368 03/29/2011 21297633 Anderson CA 02/06/2011 Nat Genet Ulcerative colitis 17q12 17 38040763 IKZF3, ORMDL3, IKZF3, PNMT, ZPBP2, GSDML ZPBP2 - GSDMB rs2872507-A rs2872507 2872507 Intergenic 2 0.46 5E-11 1.15 17 38080642 38081047 17 38040763 38040763 -0.413018589925 6.76005416816E-8 0.411369670302 -0.671838565873 0.0650500402366 2.736559E-5 06/13/2010 20453842 Stahl EA 05/09/2010 Nat Genet Rheumatoid arthritis 17q12 17 38040763 IKZF3 ZPBP2 - GSDMB rs2872507-A rs2872507 2872507 Intergenic 2 0.47 9E-7 1.10 17 38080642 38081047 17 38040763 38040763 -0.413018589925 6.76005416816E-8 0.411369670302 -0.671838565873 0.0650500402366 2.736559E-5 09/21/2011 21829393 Plagnol V 08/04/2011 PLoS Genet Type 1 diabetes autoantibodies 17q12 17 38040763 ORMDL3 ZPBP2 - GSDMB rs2872507-A rs2872507 2872507 Intergenic 2 NR 2E-6 1.10 17 38080642 38081047 17 38040763 38040763 -0.413018589925 6.76005416816E-8 0.411369670302 -0.671838565873 0.0650500402366 2.736559E-5 11/25/2008 18587394 Barrett JC 06/29/2008 Nat Genet Crohn's disease 17q12 17 38040763 ORMDL3 ZPBP2 - GSDMB rs2872507-A rs2872507 2872507 Intergenic 2 0.47 5E-9 1.12 17 38080642 38081047 17 38040763 38040763 -0.413018589925 6.76005416816E-8 0.411369670302 -0.671838565873 0.0650500402366 2.736559E-5 03/29/2011 21297633 Anderson CA 02/06/2011 Nat Genet Ulcerative colitis 17q12 17 38040763 IKZF3, ORMDL3, IKZF3, PNMT, ZPBP2, GSDML ZPBP2 - GSDMB rs2872507-A rs2872507 2872507 Intergenic 2 0.46 5E-11 1.15 17 38028921 38029301 17 38040763 38040763 1.18976421924 1.26821189815E-11 -1.07101533527 0.781824485588 0.135546735257 1.536647E-8 06/13/2010 20453842 Stahl EA 05/09/2010 Nat Genet Rheumatoid arthritis 17q12 17 38040763 IKZF3 ZPBP2 - GSDMB rs2872507-A rs2872507 2872507 Intergenic 2 0.47 9E-7 1.10 17 38028921 38029301 17 38040763 38040763 1.18976421924 1.26821189815E-11 -1.07101533527 0.781824485588 0.135546735257 1.536647E-8 09/21/2011 21829393 Plagnol V 08/04/2011 PLoS Genet Type 1 diabetes autoantibodies 17q12 17 38040763 ORMDL3 ZPBP2 - GSDMB rs2872507-A rs2872507 2872507 Intergenic 2 NR 2E-6 1.10 17 38028921 38029301 17 38040763 38040763 1.18976421924 1.26821189815E-11 -1.07101533527 0.781824485588 0.135546735257 1.536647E-8 11/25/2008 18587394 Barrett JC 06/29/2008 Nat Genet Crohn's disease 17q12 17 38040763 ORMDL3 ZPBP2 - GSDMB rs2872507-A rs2872507 2872507 Intergenic 2 0.47 5E-9 1.12 17 38028921 38029301 17 38040763 38040763 1.18976421924 1.26821189815E-11 -1.07101533527 0.781824485588 0.135546735257 1.536647E-8 04/02/2010 20228799 McGovern DP 03/14/2010 Nat Genet Ulcerative colitis 17q12 17 38051348 GSDMB ZPBP2 - GSDMB rs8067378-A rs8067378 8067378 Intergenic 2 NR 1E-7 1.12 17 38080642 38081047 17 38051348 38051348 -0.481905082246 4.90990357863E-10 0.501849942724 -0.741349044799 0.0623219011896 3.710757E-7 04/02/2010 20228799 McGovern DP 03/14/2010 Nat Genet Ulcerative colitis 17q12 17 38051348 GSDMB ZPBP2 - GSDMB rs8067378-A rs8067378 8067378 Intergenic 2 NR 1E-7 1.12 17 38028921 38029301 17 38051348 38051348 1.37131194104 2.16336398589E-15 -1.3154296691 0.852217635117 0.120266594704 9.180834E-12 04/02/2010 20228799 McGovern DP 03/14/2010 Nat Genet Ulcerative colitis 17q12 17 38062196 ORMDL3,ZPBP2M,GSDML GSDMB rs2305480-A rs2305480 2305480 missense 1 NR 3E-8 1.15 17 38080642 38081047 17 38062196 38062196 -0.413018589925 6.76005416816E-8 0.411369670302 -0.671838565873 0.0650500402366 2.736559E-5 10/14/2010 20860503 Moffatt MF 09/23/2010 N Engl J Med Asthma 17q12 17 38062196 GSDMB GSDMB rs2305480-G rs2305480 2305480 missense 1 0.55 1E-7 1.18 17 38080642 38081047 17 38062196 38062196 -0.413018589925 6.76005416816E-8 0.411369670302 -0.671838565873 0.0650500402366 2.736559E-5 04/02/2010 20228799 McGovern DP 03/14/2010 Nat Genet Ulcerative colitis 17q12 17 38062196 ORMDL3,ZPBP2M,GSDML GSDMB rs2305480-A rs2305480 2305480 missense 1 NR 3E-8 1.15 17 38028921 38029301 17 38062196 38062196 1.18976421924 1.26821189815E-11 -1.07101533527 0.781824485588 0.135546735257 1.536647E-8 10/14/2010 20860503 Moffatt MF 09/23/2010 N Engl J Med Asthma 17q12 17 38062196 GSDMB GSDMB rs2305480-G rs2305480 2305480 missense 1 0.55 1E-7 1.18 17 38028921 38029301 17 38062196 38062196 1.18976421924 1.26821189815E-11 -1.07101533527 0.781824485588 0.135546735257 1.536647E-8 08/20/2011 21804549 Torgerson DG 07/31/2011 Nat Genet Asthma 17q12 17 38064405 GSDMB GSDMB rs11078927-? rs11078927 11078927 intron 1 NR 2E-16 NR 17 38080642 38081047 17 38064405 38064405 -0.413018589925 6.76005416816E-8 0.411369670302 -0.671838565873 0.0650500402366 2.736559E-5 08/20/2011 21804549 Torgerson DG 07/31/2011 Nat Genet Asthma 17q12 17 38064405 GSDMB GSDMB rs11078927-? rs11078927 11078927 intron 1 NR 2E-16 NR 17 38028921 38029301 17 38064405 38064405 1.18976421924 1.26821189815E-11 -1.07101533527 0.781824485588 0.135546735257 1.536647E-8 06/01/2009 19430480 Barrett JC 05/10/2009 Nat Genet Type 1 diabetes 17q12 17 38066240 ORMDL3 GSDMB rs2290400-? rs2290400 2290400 intron 1 0.50 6E-13 1.15 17 38080642 38081047 17 38066240 38066240 -0.481905082246 4.90990357863E-10 0.501849942724 -0.741349044799 0.0623219011896 3.710757E-7 06/01/2009 19430480 Barrett JC 05/10/2009 Nat Genet Type 1 diabetes 17q12 17 38066240 ORMDL3 GSDMB rs2290400-? rs2290400 2290400 intron 1 0.50 6E-13 1.15 17 38028921 38029301 17 38066240 38066240 1.37131194104 2.16336398589E-15 -1.3154296691 0.852217635117 0.120266594704 9.180834E-12 11/25/2008 17611496 Moffatt MF 07/26/2007 Nature Asthma 17q12 17 38069949 ORMDL3 GSDMB rs7216389-T rs7216389 7216389 intron 1 0.52 9E-11 1.45 17 38080642 38081047 17 38069949 38069949 0.481905082246 4.90990357863E-10 -0.461960221769 0.741349044799 0.0623219011896 3.710757E-7 11/25/2008 17611496 Moffatt MF 07/26/2007 Nature Asthma 17q12 17 38069949 ORMDL3 GSDMB rs7216389-T rs7216389 7216389 intron 1 0.52 9E-11 1.45 17 38028921 38029301 17 38069949 38069949 -1.37131194104 2.16336398589E-15 1.42719421297 -0.852217635117 0.120266594704 9.180834E-12 07/09/2012 22561531 Wan YI 05/05/2012 Thorax Asthma 17q12 17 38089344 ORMDL3 ORMDL3 - GSDMA rs4794820-? rs4794820 4794820 Intergenic 2 NR 1E-8 1.33 17 38080642 38081047 17 38089344 38089344 0.369235203779 5.96684130208E-6 -0.395551258389 0.587010119985 0.0727476595114 0.001278711 01/11/2011 21150878 Ferreira MA 12/08/2010 Eur J Hum Genet Asthma 17q12 17 38095174 ORMDL3 ORMDL3 - GSDMA rs6503525-C rs6503525 6503525 Intergenic 2 0.43 5E-7 1.33 17 38080642 38081047 17 38095174 38095174 0.308574378353 1.74922257083E-4 -0.29998366939 0.501943914571 0.0759578411065 0.02030068 10/14/2010 20860503 Moffatt MF 09/23/2010 N Engl J Med Asthma 17q21.1 17 38121993 GSDMA GSDMA rs3894194-A rs3894194 3894194 missense 1 0.45 5E-9 1.17 17 38080642 38081047 17 38121993 38121993 0.307326330149 2.50157794778E-4 -0.292587257046 0.491443461407 0.0778038677988 0.02683352 03/18/2011 21292315 Nalls MA 02/01/2011 Lancet Parkinson's disease 17q21.31 17 43714850 MAPT MGC57346 rs2942168-G rs2942168 2942168 1 0.78 1E-28 1.27 17 43670351 43670799 17 43714850 43714850 1.21549278351 1.58285503095E-12 -0.513391274517 0.801600190678 0.129507931738 2.526564E-9 12/10/2009 19915575 Simon-Sanchez J 11/15/2009 Nat Genet Parkinson's disease 17q21.31 17 43719143 MAPT, C17orf69, KIAA1267, LOC644246 C17orf69 rs393152-A rs393152 393152 1 0.82 2E-16 1.30 17 43670351 43670799 17 43719143 43719143 1.19938251967 3.84352946509E-12 -0.529643165719 0.79342834469 0.131440542575 5.473849E-9 10/16/2011 21940522 Shaffer JR 09/21/2011 J Dent Res Dental caries 17q22 17 56584205 Intergenic MTMR4 rs2302189-? rs2302189 2302189 missense 1 NR 8E-6 1.33 17 56598169 56598630 17 56584205 56584205 -0.59155371139 6.49823107826E-4 0.519695975501 -0.461650589312 0.162381538983 0.05572647 09/24/2011 21833088 Sawcer S 08/11/2011 Nature Multiple sclerosis 17q23.1 17 58024275 RPS6KB1 RPS6KB1 rs180515-G rs180515 180515 UTR-3 1 NR 9E-8 1.09 17 57976434 57976875 17 58024275 58024275 0.891786456054 2.14899801367E-5 -0.596630459445 0.557403877796 0.189756767973 0.003733264 11/08/2011 21998595 N'Diaye A 10/06/2011 PLoS Genet Height 17q23.3 17 61977248 Intergenic CSH1 - CSHL1 rs2854160-T rs2854160 2854160 Intergenic 2 0.21 5E-8 .05 17 61974201 61974701 17 61977248 61977248 -0.671323756071 9.99377773936E-4 0.85449825193 -0.44728010597 0.191771134743 0.07590139 12/29/2009 20031577 Danik JS 04/01/2009 Circ Cardiovasc Genet Fibrinogen 17q25.1 17 72699833 CD300LF, SLC9A3R1, NAT9 CD300LF;RAB37 rs10512597-A rs10512597 10512597 intron;intron 1 0.18 8E-11 6.45 17 72682977 72683344 17 72699833 72699833 -0.808621767338 8.70292130446E-5 1.42852287793 -0.521501242302 0.189002959035 0.0116874 11/25/2008 18521091 Volpi S 06/03/2008 Mol Psychiatry Response to iloperidone treatment (QT 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74101941 74101941 0.621348437823 1.7078119291E-4 -0.423966292836 0.50263513555 0.152668222039 0.01992169 05/25/2012 22493691 Eriksson N 04/06/2012 PLoS One Hypothyroidism 19p13.2 19 7223848 INSR INSR rs4804416-G rs4804416 4804416 intron 1 0.423 5E-6 1.13 19 7242889 7243297 19 7223848 7223848 0.772103998074 7.7079701357E-7 -0.642083755565 0.628937576441 0.13634710706 2.245739E-4 01/25/2012 20686565 Teslovich TM 08/05/2010 Nature HDL cholesterol 19p13.2 19 8433196 ANGPTL4 ANGPTL4 rs7255436-C rs7255436 7255436 intron 1 0.47 3E-8 .45 19 8461504 8461961 19 8433196 8433196 -0.54572235607 1.24536546273E-4 0.662444917392 -0.511610276152 0.130929534225 0.0155875 01/25/2012 20686565 Teslovich TM 08/05/2010 Nature HDL cholesterol 19p13.2 19 8433196 ANGPTL4 ANGPTL4 rs7255436-C rs7255436 7255436 intron 1 0.47 3E-8 .45 19 8428307 8428808 19 8433196 8433196 0.574624238193 8.91127479377E-4 -0.689931313491 0.451169210573 0.162377072855 0.06976397 11/03/2009 19862010 Ganesh SK 10/11/2009 Nat Genet Mean corpuscular volume 19p13.2 19 12932269 RTBDN RNASEH2A - RTBDN rs7255045-A rs7255045 7255045 Intergenic 2 NR 2E-12 .00 19 12943375 12944139 19 12932269 12932269 -0.542389186351 0.00101135921143 0.242861492055 -0.446873187262 0.155115884957 0.07664731 03/10/2012 22228203 Aslibekyan S 01/05/2012 Pharmacogenet Genomics Inflammatory biomarkers 19p13.12 19 15724203 CYP4F8 CYP4F8 rs3764563-? rs3764563 3764563 nearGene-5 1 NR 3E-7 NR 19 15742636 15743011 19 15724203 15724203 -0.952839633601 1.01103626802E-4 1.61275477683 -0.517400812663 0.225132459652 0.01321094 02/08/2010 20081857 Saxena R 01/17/2010 Nat Genet Two-hour glucose challenge 19q13.32 19 46182304 GIPR GIPR rs10423928-A rs10423928 10423928 intron 1 NR 3E-12 .09 19 46181156 46181549 19 46182304 46182304 0.796752448606 5.82390692252E-4 -0.287365686339 0.465210478457 0.216579492204 0.05115548 09/10/2010 20663923 Anney R 07/27/2010 Hum Mol Genet Autism 20p12.1 20 14747471 MACROD2 MACROD2 rs4141463-? rs4141463 4141463 intron 1 0.57 4E-8 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0.163605427089 0.004659946 11/25/2008 18758464 Kugathasan S 08/31/2008 Nat Genet Inflammatory bowel disease 20q13.33 20 62343956 TNFRSF6B ZGPAT rs2315008-G rs2315008 2315008 intron 1 0.69 9E-15 1.36 20 62362089 62362464 20 62343956 62343956 -0.628943405383 6.84068982671E-4 0.836336926951 -0.459968456132 0.173446994464 0.05792769 01/11/2011 21102463 Franke A 11/21/2010 Nat Genet Crohn's disease 20q13.33 20 62349586 RTEL1, TNFRS-F6B, SLC2A4RG ZGPAT rs4809330-G rs4809330 4809330 intron 1 0.71 3E-15 1.12 20 62362089 62362464 20 62349586 62349586 -0.628943405383 6.84068982671E-4 0.836336926951 -0.459968456132 0.173446994464 0.05792769 06/14/2010 20463881 Liu F 05/16/2010 PLoS Genet Eye color traits 21q22.13 21 38491095 TTC3,DSCR9 TTC3 rs1003719-A rs1003719 1003719 intron 1 NR 2E-10 .10 21 38451648 38452089 21 38491095 38491095 -0.618433270257 2.24857940268E-5 0.689774095449 -0.556303241529 0.131969464354 0.003879678 03/30/2012 22365631 Greenwood TA 02/22/2012 Biol Psychiatry Temperament-related traits 21q22.2 21 40569779 BRWD1 BRWD1 rs2150410-? rs2150410 2150410 intron 1 NR 4E-6 1.69 21 40547111 40547553 21 40569779 40569779 1.75738997409 4.69964638639E-14 -3.11313959233 0.830623257077 0.168303207893 1.278603E-10 04/20/2012 22451204 Pankratz N 03/01/2012 Ann Neurol Parkinson's disease 21q22.3 21 43286352 PRDM15 PRDM15 rs2839398-? rs2839398 2839398 intron 1 NR 5E-6 1.23 21 43282135 43282526 21 43286352 43286352 0.916217785657 2.22166755255E-5 -0.253066940246 0.556596187185 0.195365621763 0.003838077 03/29/2011 21297633 Anderson CA 02/06/2011 Nat Genet Ulcerative colitis 21q22.3 21 45615023 ICOSLG C21orf33 - ICOSLG rs2838519-G rs2838519 2838519 Intergenic 2 0.39 6E-11 1.14 21 45659281 45659688 21 45615023 45615023 -0.519172159843 2.07168757736E-4 0.543398169916 -0.497020177137 0.129487678476 0.02314324 11/25/2008 18587394 Barrett JC 06/29/2008 Nat Genet Crohn's disease 21q22.3 21 45615561 ICOSLG C21orf33 - ICOSLG rs762421-G rs762421 762421 Intergenic 2 0.39 1E-9 1.13 21 45659281 45659688 21 45615561 45615561 -0.560650610667 7.15283516119E-5 0.597496375884 -0.526788546784 0.129233470064 0.01002337 11/18/2011 22001757 Chambers JC 10/16/2011 Nat Genet Liver enzyme levels (gamma-glutamyl transferase) 22q11.23 22 24295286 DDT, DDTL, GSTT1, GSTT2B, MIF MIF - GSTT2B rs2739330-T rs2739330 2739330 Intergenic 2 0.42 2E-9 3.70 22 24326540 24326944 22 24295286 24295286 -1.34758308599 9.95914071981E-15 1.82408667959 -0.841909019722 0.123390005197 3.314265E-11 11/18/2011 22001757 Chambers JC 10/16/2011 Nat Genet Liver enzyme levels (gamma-glutamyl transferase) 22q11.23 22 24295286 DDT, DDTL, GSTT1, GSTT2B, MIF MIF - GSTT2B rs2739330-T rs2739330 2739330 Intergenic 2 0.42 2E-9 3.70 22 24272172 24272636 22 24295286 24295286 -0.7997355785 1.25992713028E-5 1.10757532754 -0.570090914321 0.164647435125 0.002397212 11/18/2011 22001757 Chambers JC 10/16/2011 Nat Genet Liver enzyme levels (gamma-glutamyl transferase) 22q11.23 22 24295286 DDT, DDTL, GSTT1, GSTT2B, MIF MIF - GSTT2B rs2739330-T rs2739330 2739330 Intergenic 2 0.42 2E-9 3.70 22 24275830 24276457 22 24295286 24295286 -0.844351813502 2.73922179911E-13 1.18071578922 -0.816713275798 0.0852245045028 5.447453E-10 11/18/2011 22001757 Chambers JC 10/16/2011 Nat Genet Liver enzyme levels (gamma-glutamyl transferase) 22q11.23 22 24295286 DDT, DDTL, GSTT1, GSTT2B, MIF MIF - GSTT2B rs2739330-T rs2739330 2739330 Intergenic 2 0.42 2E-9 3.70 22 24286485 24286857 22 24295286 24295286 -0.851937779244 6.69586350775E-10 1.19675445968 -0.737528723828 0.111439148828 4.847274E-7 10/30/2009 19820697 Soranzo N 10/11/2009 Nat Genet Hematological parameters 22q12.3 22 32867528 FBX07 BPIL2 - FBXO7 rs9609565-G rs9609565 9609565 Intergenic 2 NR 4E-10 .37 22 32869295 32869717 22 32867528 32867528 -0.508252106116 7.21461640443E-4 0.189597424722 -0.458216236168 0.14084279371 0.06011169 10/30/2009 19820697 Soranzo N 10/11/2009 Nat Genet Hematological parameters 22q12.3 22 32867528 FBX07 BPIL2 - FBXO7 rs9609565-G rs9609565 9609565 Intergenic 2 NR 4E-10 .37 22 32870620 32870981 22 32867528 32867528 0.979324471067 1.23800250958E-5 -0.432007376419 0.570499274144 0.201406875213 0.002362203 07/01/2010 20532800 Bostrom MA 06/08/2010 Hum Genet End-stage renal disease (non-diabetic) 22q12.3 22 36616445 MYH9 APOL4 - APOL2 rs4821469-? rs4821469 4821469 Intergenic 2 0.056 2E-19 2.86 22 36626909 36627337 22 36616445 36616445 -0.58645655779 0.00144100447668 0.201922527795 -0.434550343604 0.173641120012 0.09801802 03/24/2010 20228798 Franke A 03/14/2010 Nat Genet Ulcerative colitis 22q13.33 22 50435480 IL17REL IL17REL rs5771069-G rs5771069 5771069 missense 1 0.49 4E-8 1.17 22 50421757 50422153 22 50435480 50435480 0.641973985364 1.92730573305E-4 -0.702092926781 0.499131630477 0.159215734263 0.02186785 03/29/2011 21297633 Anderson CA 02/06/2011 Nat Genet Ulcerative colitis 22q13.33 22 50435480 PIM3, IL17REL IL17REL rs5771069-G rs5771069 5771069 missense 1 0.51 2E-7 1.11 22 50421757 50422153 22 50435480 50435480 0.641973985364 1.92730573305E-4 -0.702092926781 0.499131630477 0.159215734263 0.02186785