"ace-1"	"X"	23.6	"[C.elegansII] p1000 : class A acetylcholinesterase reduced 100\%\; no behavioral phenotype alone (ES1 ME3) but ace-2\;ace-1 is uncoordinated (hypercontracted) and ace-2\;ace-3\;ace-1 is L1 lethal.  Mosaic focus in muscle.  OA6: e1572 etc.Cloned: sequence predicts 609 aa, 37\% identity with Torpedo acetylcholinesterase.  p1000 is W99op. [Herman and Kari 1985\; Arpagaus et al. 1994\; FF]"	
"ace-2"	"I"	-4.94219	"[C.elegansII] g72 : class B acetylcholinesterase reduced 98\%\; no behavioral phenotype alone (see ace-1). ES1 ME3. OA11: g73 etc. [Culotti et al. 1981]"	
"ace-3"	"II"	22.6285	"[C.elegansII] dc2 : class C acetylcholinesterase reduced >95\%\; no behavioral phenotype (see ace-1). ES1. OA1: dc3. [Johnson et al. 1988]"	
"act-4"	"X"	-6.27	"[C.elegansII] NMK. Encodes actin, similar to but distinct from actin-123.  Abundant transcript.  act-4::lacZ expressed strongly in body-wall muscles, vulval muscles, spermatheca. [Krause et al. 1989\; Stone and Shaw 1993]"	
"act-123"	"V"	2.92	"[C.elegansII] st15sd : (pka unc-92) both st15 and st15\/+ small, slow-growing, uncoordinated, almost paralysed abnormal thin filament ultrastructure in muscle. ES3 ME0. NA(sd)5 (st22ts (25C phenotypes similar to st15) st119 (dominant paralysed, recessive larval lethal) etc.). All are dominant neomorphic mutations of one of the three clustered actin genes. Double mutant intragenic revertants are wildtype in phenotype even if act-1 or act-3 is disrupted (e.g. st22st283 internal deficiency in act-3).  See also emb-22. Cloned: encodes 3 actin genes act-1, act-2, act-3 (act-1 and act-3 identical coding sequence).  Mutant alterations in either act-1(st118 is K18T,D11N), act-3 (st15 is Y143N,st22 and ad767 are both Q334K) or both act-2 and act-3 (ad468, recessive lethal with dominant pharynx muscle defect). [Files et al. 1983, Krause et al. 1989, DA]"	
"adn-1"	"I"	3.60019	"[C.elegansII] rh38 (Unc and slightly Dpy, many axon trajectories are abnormal, excretory canals are short, distal tip cells detach from germ cells, and first polar bodies rest in abnormally posterior positions. rh38\/+ is not Unc, but  has axonal, canal, distal tip cell, and polar body abnormalities. rh38\/Df is approximately wild-type. The intragenic revertants are impenetrant Uncs), rh240, rh38rh272,rh38rh408, rh38rh409, rh38rh410. [NJ]"	
"adn-2"	"V"	0.014709	"[C.elegansII] rh162 : excretory canals are short\; alae areabnormal\; distal tip cells detach from germ cells\; first polar body ends up in posterior positions. [NJ]"	
"adp-1"	"II"	2.61044	"[C.elegansII] ky20 : fails to adapt to a subset of odorants detected by AWC (benzaldehyde, butanone\; normaladaptation to diacetyl, isoamyl alcohol).See also osm-9. [Colbert & Bargmann 1995 ]"	
"aex-1"	"I"	2.24063	"[C.elegansII] sa9: defecation defective, severely constipated, anterior body contraction (aBoc) and expulsion muscle contraction (Exp) steps of defecation nearly always missing, adult males not constipated and mate well.  OA3: sa10, sa27 (weaker), sa49 (weaker)[Thomas 1990: JT]"	
"aex-2"	"X"	1.16029	"[C.elegansII] sa3 : defecation defective, severely constipated, expulsion muscle contraction (Exp) nearly always absent, anterior body contraction (aBoc) either absent or mistimed, adult male unaffected and mates well.  OA1: sa21 (similar) [Thomas 1990\; JT]"	
"aex-3"	"X"	-19.1022	"[C.elegansII] ad418 : defecation defective, slightly constipated, anterior body contraction (aBoc) and expulsion muscle contraction (Exp) missing in five of six defecation cycles, adult males unaffected and mate well.  Interactions (Daf-c and Eat) with unc-31.  OA3: sa5, ad696, n2166. Cloned: cosmid C02H7 [Thomas 1990\; JT, DA]"	
"aex-4"	"X"	-10.1761	"[C.elegansII] sa22 : defecation defective, moderately constipated, anterior body contraction (aBoc) and expulsion muscle contraction (Exp) missing in about 6 of 7 defecation cycles, adult males unaffected and mate well. [Thomas 1990\; JT]"	
"aex-5"	"I"	27.2055	"[C.elegansII] sa23 : defecation defective, moderate to severe constipation, expulsion muscle contraction (Exp) missing in about 9 of 10 defecation cycles, anterior body contraction (aBoc) usually missing as well, adult males unaffected and mate well.  OA3: sa41, sa42, sa43 (all similar) [Thomas 1990\; JT]"	
"aex-6"	"I"	21.8557	"[C.elegansII] sa24 : defecation defective, moderately to severely constipated, expulsion muscle contraction (Exp) missing in about 9 of 10 defecation cycles, anterior body contraction (aBoc) usually also missing, slightly sluggish and slight egg laying defect (Egl). [Thomas 1990\; JT]"	
"age-1"	"II"	3.55715	"[C.elegansII] m333mat : nonconditional, constitutive formationof dauers and dauer-like larvae\; maternally rescued adults are Egl\; increased lifespan\; probably allelic with age-1. ES3(L3).OA>4: mg44, etc. [Gottlieb and Ruvkun 1994\; Larsen et al. 1995\; DR\; GR]"	
"ali-1"	"V"	3.27834	"[C.elegansII] e1934 : faint or invisible alae in L1. ES1 ME3. NA1. [CF]"	
"ama-1"	"IV"	0.050329	"[C.elegansII] m118sd : heterozygote m118\/+ resistant to 400ug\/ml alpha-amanitin\; altered RNA polymerase II, no other phenotype. ES1. OA>30 (intragenic revertants): m118m221 (L1 lethal, probable null),m118m235 (late larval lethal),m118m252 (embryonic lethal), m118m238ts (sterile adult), etc.  Also hyper-resistant allele m118m526 (sterile25C, 80\% embryonic lethal at 20C.)[Rogalski et al. 1988, 1990]"	
"ama-2"	"V"	4.85332	"[C.elegansII] m323dm : heterozygote m323\/+ resistant to 100 ug\/ml alpha-amanitin\; recessive lethal. ES1. NA1. [Rogalski et al. 1988}"	
"anc-1"	"I"	-1.4444	"[C.elegansII] e1753amb : nuclei of hypodermal cells not elastically anchored\; other cytoskeletal abnormalities\; no gross phenotype. Enhances multivulva phenotype of lin-15 mutants, without change in lineage.e1753\/Df is very unhealthy. ES1. OA4: e1802, e1873, e1874, e1885(all resemble e1753\;  all alleles tend to revert spontaneously by intragenic reversion). e1753, e1802, e1873, e1874, e1885 [Hedgecock and Thomson 1982\;  CZ]"	
"aph-1"	"I"	3.61161	"[C.elegansII] zu123 : maternal effect lethal, no anterior pharynx\;resembles Glp-1 embryonic phenotype but no Lag or germ line phenotypes.  Maternal rescue complete.OA1: zu147 (weaker allele). [JJ]"	
"aph-1"	"I"	3.61161	"[C.elegansII] zu123 : maternal effect lethal, no anterior pharynx\;resembles Glp-1 embryonic phenotype but no Lag or germ line phenotypes.  Maternal rescue complete.OA1: zu147 (weaker allele).[JJ]"	
"aph-2"	"I"	4.9	"[C.elegansII] Mutation maternal effect lethal, no anterior pharynx\;resembles Aph-1\; Egl.Cloned: novel protein, 722 aa with signal sequence\; antibody staining indicates APH-2 present on membranes of all late oocytes and early blastomeres. [JJ]"	
"aph-2"	"I"	4.9	"[C.elegansII] Mutation maternal effect lethal, no anterior pharynx\;resembles Aph-1\; Egl.Cloned: novel protein, 722 aa with signal sequence\; antibody staining indicates APH-2 present on membranes of all late oocytes and early blastomeres.[JJ]"	
"apx-1"	"V"	-10.1723	"[C.elegansII] or3mat : maternal effect lethal, extraanterior pharyngeal cells,ABp fails to produce intestinal valve cells.OA1: zu183.Cloned: predicted protein with similarity to Delta, Serrate, LAG-2.  Can substitute for lag-2 , if fused to lag-2 promoter. [Mello et al. 1994\; Gao and Kimble 1995\; JJ\; BB\; JK\; GS]"	
"bar-1"	"X"	-1.99174	"[C.elegansII] mu63spo : suppresses pry-1(mu38). mu63 alone leads to ts defect in the migration of the QL descendants. NA1. [CF]"	
"bas-1"	"III"	-0.818014	"[C.elegansII] ad446 : serotonin-deficient (nodetectable serotonin immunoreactivity)\;serotonin immunoreactivity restored by exposure to serotonin, but not to 5-hydroxytryptophan\; poor male turning behavior [Loer and Kenyon 1993\; LC\; DA]"	
"ben-1"	"III"	-6.66436	"[C.elegansII] e1880ts,sd : resistant to 14fM benomyl no other phenotype. ES1. OA>20: e1910, u102, u134 etc. (all somewhat ts and sd). Cloned: encodes beta-tubulin. [Driscoll et al. 1989]"	
"bli-1"	"II"	3.04537	"[C.elegansII] e769 : adult symmetrically blistered,especially head\; enhanced 25C. ES3 (old adult) ME2. OA6: e770, e935 (weaker allele) e993spo, e1610 etc. Spontaneous mutations frequent. [Brenner 1974\; CB]"	
"bli-2"	"II"	-1.26657	"[C.elegansII] e768 : adult blistered especially head\; slightly small\; enhanced 25C. ES3 (old adult) ME2. OA3: e107, e527, e772. [Brenner 1974\; CB]"	
"bli-3"	"I"	-18.6971	"[C.elegansII]e767 : small irregular shape variable slight blistering in adult. ES2 (adult late larvae) ME1. OA1: n529. [Brenner 1974\; CB]"	
"bli-4"	"I"	0.907283	"[C.elegansII] e937 : adult blistered,  especially head\; penetrance 90\%\; unique Class I allele. ES3 (old adult) ME1. OA13: all other alleles result in late embryonic lethality, most are class II, fail to complemente937. e.g. h42, h199, h254, h1403.  Also s90(pka let-77, class III allele, late larval lethal,complements e937 but not other alleles)Cloned:  multiple alternatively spliced transcripts,  encoding predicted endoproteases (KEX2\/subtilisin class) with different C-termini,[Peters et al. 1991, Thacker et al. 1995, KR]"	
"bli-5"	"III"	21.4491	"[C.elegansII] e518 : small dumpyish adult, blistered, especially around pharynx\; abnormal bursa in adult male. ES3 (adult late larvae) ME0. OA1: s277 (induced on eT1). [Brenner 1974\; CB\; BC]"	
"bli-6"	"IV"	3.17545	"[C.elegansII] sc16 : adult blistered, both head and body\; often small blisters. ES3 (old adult). OA>4: n776sd, mn4dm (mn4\/+ always blistered),revertants of mn4.  Null phenotype uncertain. [Park and Horvitz 1986\; BE\; SP]"	
"cad-1"	"II"	23.0346	"[C.elegansII] j1 : 90\% reduced cathepsin D\; gut cells appear more vacuolated and bubbly\; gross phenotype WT.  OA2: j12, j14 (similar).Probable structural gene for cathepsin D. [Jacobson et al. 1988]"	
"can-1"	"III"	7.02485	"[C.elegansII] rh67 : CAN migrates normally, but retains a neuronal phenotype and usually dies. Animals are pale and have withered tails."	
"cap-2"	"II"	3.05724	"[C.elegansII] NMK.  Encodes homolog of actin capping protein, beta subunit.Functional in yeast. [Waddle et al. 1993]"	
"cap-2"	"II"	3.05724	"[C.elegansII] NMK.  Encodes homolog of actin capping protein, beta subunit.Functional in yeast.[Waddle et al. 1993]"	
"cat-1"	"X"	-4.25143	"[C.elegansII] e1111amber : dopamine and serotonin absent from neuron processes present in cell bodies\; poor male turning behavior\; enhanced foraging behavior, suppressed by serotonin agonists\;serotonin immunoreactivity restored by exogenous serotonin or 5-hydroxytryptophan\;ES1, ME1. OA1: n733. [Sulston et al. 1975\; Loer and Kenyon 1993\; KP\; LC]"	
"cat-2"	"II"	-17.8685	"[C.elegansII] e1112 : dopamine reduced > 95\%\; serotonin normal\; no defect in male turning behavior. ES1 ME3 NA1. [Sulston et al. 1975, Loer and Kenyon 1993\; LC]"	
"cat-4"	"V"	2.77783	"[C.elegansII] e1141 : dopamine reduced > 90\%, serotonin reduced orabsent\; poor male turning behavior\; enhanced foraging behavior, suppressed by serotonin agonists\;  serotonin immunoreactivity restored by exogenous serotonin or 5-hydroxytryptophan\;cuticle defective, hypersensitive to SDS, levamisole,hypochlorite.. ES1 ME2 NA1. [Sulston et al. 1975\; Loer and Kenyon 1993\; DA\; KP\; LC]"	
"cat-6"	"V"	4.96913	"[C.elegansII] e1861 : sensory neurons CEP, ADE, PDE take up FITC\; tubular body of CEP cilia disrupted\;abnormal cilia in CEP, OLL\; slightly defective dauer formation. ES1 ME3. NA1. [Hedgecock et al. 1985\; Perkins et al. 1986]"	
"ced-1"	"I"	13.3038	"[C.elegansII] e1735 : programmed cell deaths abnormal, dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; engulfment group A (ced-1,6,7)\; no gross phenotype. ES1. OA>10: n1506spo, e1754,e1797, e1798, e1799, e1800, e1801, e1814, n691, n21506, n2000, n2092 (all alleles similar)[Hedgecock et al. 1983\; Ellis et al. 1991\; MT]"	
"ced-2"	"IV"	-19.0557	"[C.elegansII] e1752 : programmed cell deaths abnormal,dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; engulfment group B (ced-2,5,10 : suppressvulvaless phenotype of lin-24, lin-33)\;extensive maternal rescue\; no gross phenotype ES1. OA1: n1994. [Hedgecock et al. 1983\; Ellis et al. 1991\; MT]"	
"ced-3"	"IV"	8.21455	"[C.elegansII] n717 : programmed cell deaths fail to occur\; epistatic to ced-1, ced-2 and nuc-1\; recessive suppressor of egl-1 and of egg-laying defect of egl-41 homozygotes\; semidominant suppressor of egl-1 (n487)\/+ and egl-41(n1069)\/+ heterozygotes\; no gross phenotype. ES1 (ES2 in egl-1 background) ME3. OA>10: n718, n1129, n1163, n1164,n1165, n1286, pk59tci.Cloned: 2.9 kb RNA, predicted protein 503aa, 56 kD\;similarity (29\% identity) to mammalian ICE(interleukin-1 beta converting enzyme)\;antibodies detect 34 kD and 12kD species. [Yuan et al. 1993\; MT]"	
"ced-4"	"III"	-2.53522	"[C.elegansII] n1162 : programmed cell deaths fail to occur\; recessive suppressor of egl-1 and egl-41 homozygotes\; no gross phenotype. ES1 (ES2 in egl-1 background) ME3. OA>10: n1894, n1920, n1461 (Tc4 insertion, also revertants n1561n1712, n1416n1713), n2273  (anomalous allele, enhances cell death by synergy with ced-9(lf), but reduces cell death alone), etc.Cloned: major transcript 2.2 kb, encodes 549aa novel protein, 65 kD (confirmed by antibody)\; minor 2.3 kb transcript (alternatively spliced,may inhibit cell death). [Yuan and Horvitz 1992\; MT]"	
"ced-5"	"IV"	4.65	"[C.elegansII] n1812 : programmmed cell deaths abnormal, dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; engulfment group B (ced-2,5,10 : suppress vulvaless phenotype of lin-24, lin-33)\; Mig, hermaphrodite distal tip cells execute extra turns\; extensive maternal rescue\; no gross phenotype.  OA1: n2002.Cloned : 5.6 kb transcript, predicted protein 180 kD, novel. [Ellis et al. 1991\; MT\; NF\; ZB]"	
"ced-5"	"IV"	4.65	"[C.elegansII] n1812 : programmmed cell deaths abnormal, dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; engulfment group B (ced-2,5,10 : suppress vulvaless phenotype of lin-24, lin-33)\; Mig, hermaphrodite distal tip cells execute extra turns\; extensive maternal rescue\; no gross phenotype.  OA1: n2002.Cloned : 5.6 kb transcript, predicted protein 180 kD, novel.[Ellis et al. 1991\; MT\; NF\; ZB]"	
"ced-6"	"III"	-1.53181	"[C.elegansII] n2095 : programmed cell deaths abnormal, dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; engulfment group A (ced-1,6,7)\;extensive maternal rescue\; no gross phenotype.  OA1: n1813. [Ellis et al. 1991\; MT]"	
"ced-6"	"III"	-1.53181	"[C.elegansII] n2095 : programmed cell deaths abnormal, dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; engulfment group A (ced-1,6,7)\;extensive maternal rescue\; no gross phenotype.  OA1: n1813.[Ellis et al. 1991\; MT]"	
"ced-7"	"III"	0.503312	"[C.elegansII] n1892 : programmed cell deaths abnormal, dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; engulfment group A (ced-1,6,7)\; extensive maternal rescue\; no gross phenotype. OA6: n1893, n1896, n1996,n1997, n1998, n2001, n2094.Cloned: encodes 191 kD protein, similarity to ABCtransporter proteins. [Ellis et al. 1991\; MT\; ZB]"	
"ced-7"	"III"	0.503312	"[C.elegansII] n1892 : programmed cell deaths abnormal, dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; engulfment group A (ced-1,6,7)\; extensive maternal rescue\; no gross phenotype. OA6: n1893, n1896, n1996,n1997, n1998, n2001, n2094.Cloned: encodes 191 kD protein, similarity to ABCtransporter proteins.[Ellis et al. 1991\; MT\; ZB]"	
"ced-8"	"X"	-0.044954	"[C.elegansII] n1891 : programmed cell deaths abnormal and protracted\; dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; superficially resembles engulfment group A (ced-1,6,7)\; but synergizes with weak ced-3 alleles in preventing cell death\; no gross phenotype.  OA3: n1999, n2090, n2093. Cloned: encodes predicted novel protein. [Ellis et al. 1991\; MT]"	
"ced-8"	"X"	-0.044954	"[C.elegansII] n1891 : programmed cell deaths abnormal and protracted\; dying cells arrest at highlyrefractile stage\; killer cells fail to engulf target cells\; superficially resembles engulfment group A (ced-1,6,7)\; but synergizes with weak ced-3 alleles in preventing cell death\; no gross phenotype.  OA3: n1999, n2090, n2093.Cloned: encodes predicted novel protein.[Ellis et al. 1991\; MT]"	
"ced-9"	"III"	2.42229	"[C.elegansII] n1950sd : gf allele, reduced cell deaths. Intragenic lf revertants increase cell death:n1950n2077 (partial sterility, Mel, very sick embryo),  n1950n2161 (weaker lf, Mel, ectopic cell deaths in embryo), n1653ts (weak lf, viable). Cloned: 2.1 kb (cyt-1 + ced-9) and 1.3 kb transcripts, latter encodes 280 aa protein related to mammalian bcl-2 (23\% identity).3' of cyt-1, immediately adjacent, shares regulation. [Hengartner et al. 1992\; Hengartner and Horvitz 1994\;MT]"	
"ced-10"	"IV"	-1.82713	"[C.elegansII] n1993 : dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; engulfment group B (ced-2,5,10 : suppress vulvaless phenotype of lin-24, lin-33)\;extensive maternal rescue\; no gross phenotype. [Ellis et al. 1991\; MT]"	
"ced-10"	"IV"	-1.82713	"[C.elegansII] n1993 : dying cells arrest at highly refractile stage\; killer cells fail to engulf target cells\; engulfment group B (ced-2,5,10 : suppressvulvaless phenotype of lin-24, lin-33)\;extensive maternal rescue\; no gross phenotype.[Ellis et al. 1991\; MT]"	
"ced-11"	"III"	0.148405	"[C.elegansII] n2744 : abnormal programmed cell death corpses OA3: n2745, n2832, n2833, n2834Cloned: encodes predicted novel protein. [MT]"	
"ceh-6"	"I"	2.85	"[C.elegansII] mg60 : embryonic or L1 lethal, malformed rectum,rectal rupture at or after 2-fold stage.  mg60 is 1.6 kb deletion derived from Tc1 insertion pk33. Antibody stains strong or transiently in a variety of neuronal tissues, excretory cell, rectal cells Y, K, F, B, U. Encodes homeoprotein, POU III subclass. [Burglin et al. 1989\; TB]"	
"ceh-10"	"III"	-1.43	"[C.elegansII] NMK.  1.2 kb transcript, encodes 344 aa Paired-like class homeoprotein\; extensive similarity to mouse Chx10, goldfish Vsx-1.  ceh-10:lacZ expressed maximally in embryo, from 250-300 cell stage, lower in larvae, in certain neuronal nuclei (interneurons AIY, AIN\; sensory neurons CEPD, motor neurons RID, RMED\; CAN cells etc.).  Transgene can induce defects in CAN cell migration and withered tail phenotype. [Hawkins and McGhee 1990\; Svendsen and McGhee 1995\; JM]"	
"ceh-10"	"III"	-1.43	"[C.elegansII] NMK.  1.2 kb transcript, encodes 344 aa Paired-like class homeoprotein\; extensive similarity to mouse Chx10, goldfish Vsx-1.  ceh-10:lacZ expressed maximally in embryo,from250-300 cell stage, lower in larvae, in certain neuronal nuclei (interneurons AIY, AIN\; sensoryneurons CEPD, motor neurons RID, RMED\; CAN cellsetc.).  Transgene can induce defects in CAN cell migration and withered tail phenotype. [Hawkins and McGhee 1990\; Svendsen and McGhee 1995\; JM]"	
"ceh-20"	"III"	-0.818299	"[C.elegansII] ay9 : Vul, Egl, SM migration defects. Stronger alleles are larval lethal, Unc,defective in Q daughter migrations, M lineage. Males do not mate, have defective tails.  OA3: ay412 (severe Unc, Vul), ay37,ay38 (both larval lethal). Encodes PBC class homeoprotein.  Antibody stains posterior of embryo, RVG and VNC of larva\; weak staining in body muscle and hypodermis. [Burglin and Ruvkun 1992\; NH\; TB]"	
"ceh-22"	"V"	2.79924	"[C.elegansII] cc8266te : pharyngeal defects, poor feeding, some larval arrest.  OA1: pk40tci Encodes protein related (83\%) to NK-2 of Drosophila.Candidate binding protein for myo-2 enhancer.  ceh-22:lacZ expressed in pharyngeal muscle. [Okkema and Fire 1994]"	
"ces-1"	"I"	2.92453	"[C.elegansII] n703 : sisters of NSM, I2 fail to undergo programmed cell death (gf allele).  OA2 (gf): n1895, n1896 (similar).lf alleles (probable null) wild type but suppress ces-2 mutations. Cloned: encodes zinc finger protein, most related to snail of Drosophila. [Ellis and Horvitz 1991\; MT]"	
"ces-1"	"I"	2.92453	"[C.elegansII] n703 : sisters of NSM, I2 fail to undergo programmed cell death (gf allele).  OA2 (gf): n1895, n1896 (similar).lf alleles (probable null) wild type but suppress ces-2 mutations.Cloned: encodes zinc finger protein, mostrelated to snail of Drosophila.[Ellis and Horvitz 1991\; MT]"	
"ces-2"	"I"	29.0617	"[C.elegansII] n732 : sisters of NSM (but not I2) fail to undergo programmed cell death. Cloned: encodes protein related to bZIP transcription factors. [Ellis and Horvitz 1991\; MT]"	
"ces-2"	"I"	29.0617	"[C.elegansII] n732 : sisters of NSM (but not I2) fail to undergo programmed cell death.Cloned: encodes protein related to bZIP transcription factors.[Ellis and Horvitz 1991\; MT]"	
"cha-1"	"IV"	-3.31327	"[C.elegansII] p1152 : 99\% reduced choline acetyltransferase, slow-growing, uncoordinated (coiler), Ric (resistant to aldicarb, trichlorfon)\; slow pumping. ES3. OA>10: m324 (lethal, probable null),b401ts (ME2), p1154, p1156 (anomalous allele, fails to complement unc-17), cn101,n2411 etc.   Defecation cycle variable in length, often extremely long in all alleles tested. unc-17 alleles e113, e876 fail to complement cha-1. Cloned : encodes choline acetyltransferase, 37\% identical to pig enzyme, 28\% to Drosophila enzyme. Antibody staining cytosolic, in motor neurons.Shares 5' UTR exon with unc-17. [Rand 1989\; Alfonso et al. 1994\; RM\; JT\; DR\; DA]"	
"che-1"	"I"	1.45632	"[C.elegansII] e1034 : non-chemotactic to sodium ion\; abnormal sensory neuroanatomy especially AFD, IL2 cells.  ES1 ME2. OA>5: e1035,  p674 (pka tax-1, normal thermotaxis, poor osmotic avoidance), p679, p680, p692, p696. [Dusenbery 1976\; Lewis and Hodgkin 1977]"	
"che-2"	"X"	-19.5458	"[C.elegansII] e1033 : non-chemotactic to sodium ion\; slightly small\; defective osmotic avoidance\; defective dauer formation\; males impotent\; Dyf (no FITC uptake)\; ciliated neurons have abnormal stunted ultrastructure. ES2. ME0.OA5: m127, mn330mut, mn395 etc. [Lewis and Hodgkin 1977\; Starich et al. 1995\; DR\; SP\; NJ]"	
"che-3"	"I"	2.31461	"[C.elegansII] e1124 : non-chemotactic to sodium ion, slightly small\; defective osmotic avoidance\; defective dauer formation\; males impotent\; ciliated neurons have abnormal stunted ultrastructure\; Dyf (no FITC uptake)\; octopamine deficient. ES2 ME0. OA>30: e1379, e1253 (pka che-8), p801 (pka osm-2), m443mut, mn333mut,sa129, etc.  Also hf5 (pka caf-2, resistant to30 mM caffeine\;no gross phenotype\; Dyf).  High forward mutation frequency. [Lewis and Hodgkin 1977\; Starich et al. 1995\; NJ\; SP\; DR]"	
"che-10"	"II"	-2.87019	"[C.elegansII] e1809 : Dyf (no FITC uptake by amphids or phasmids)\; striated ciliary rootlets missing from OLQ, IL1, BAG sensory neurons\; defective osmotic avoidance\; males impotent. ES1. OA>5: m525mut, mn403, n1514. [Perkins et al. 1986\; Starich et al. 1995\; DR\; SP\; MT]"	
"che-11"	"V"	3.57331	"[C.elegansII] e1810 : Dyf (no FITC uptake by amphids or phasmids)\; defective in osmotic avoidance and dauer formation\; irregular amphid cilia, abnormal staining, abnormal CEP cilia etc.. ES1 ME0. OA>6: e1815, m162, mn387, mn393. [Perkins et al. 1986\; Starich et al. 1995\; SP\; DR]"	
"che-12"	"V"	2.28896	"[C.elegansII] e1812 : Dyf (weak FITC uptake by amphids and phasmids)\; amphid sheath cells fail to secrete matrix material\; defective osmotic avoidance. ES1 ME3. OA3: e1813, mn389, mn399. [Perkins et al. 1986\; Starich et al. 1995]"	
"che-13"	"I"	5.01553	"[C.elegansII] e1805 : Dyf (no FITC uptake by amphids or phasmids)\; severely shortened axonemes and ectopic assembly of ciliary structures and microtubules in many sensory neurons\; defective in osmotic avoidance and dauer formation. ES1 ME0. OA2: m523mut, n1520. [Perkins et al. 1986\; Starich et al. 1995\; DR\; SP]"	
"cib-1"	"I"	-0.24992	"[C.elegansII] e2300ts : maternal effect embryonic lethal at25C, WT at 15C.  TSP in oocyte, early embryo. Mutant embryos exhibit abnormal delayed cleavage of P1, P2, P3\; other pleiotropic defects. OA6: e2303 (non-conditional strict Mel), e2301,e2302, e2304, e2305, e2306 (all ts, weaker than e2300). [Schnabel and Schnabel, 1990]"	
"cib-3"	"I"	-7.39191	"[C.elegansII] t1008 : Mel?[GE]"	
"clk-1"	"III"	-1.99372	"[C.elegansII] e2519mat : growth and behavior slowed by up to 2-fold.Profound zygotic and maternal rescue.Slow postembryonic development, slow cell cycle,long life span.  Swimming, pumping, egg-laying, defecation all slow and irregular.  OA4: qm30 (worms are viable at 20C but become sterile at 25C) qm11, qm47, qm51. Cloned: cosmid rescue (W03B11)[Wong et al. 1995]"	
"clk-2"	"III"	-0.722758	"[C.elegansII] qm37 : slow growth and rhythms, phenotypes similar to Clk-1\; profound maternal and zygotic rescue\; embryonic lethal at 25C, some lethality at all temperatures. NA1. [MQ]"	
"clk-3"	"II"	22.2455	"[C.elegansII] qm38 : slow growth and rhythms, phenotypes similar to Clk-1\; profound maternal and zygotic rescue\; no lethality.OA1 (qm53). [MQ]"	
"clr-1"	"II"	-1.92114	"[C.elegansII] e1745ts : starved translucent appearance at 20C, facilitating Nomarski visualization of neuron processes\; phenocopied by growth on 1mM orthovanadate. Inviable at 25C. Suppresses egl-15(n1477ts), and SM Mig defect of egl-17(1313)ES3 (25C) ES2 (20C). OA>30:e2530 (slightly stronger phenotype, putative null),ut41 (non-ts lethal)\; most alleles isolated as egl-15 suppressors, some of these viable, non-Clr.See also soc.Cloned: encodes protein with similarity to protein tyrosine phosphatases. [Clark et al. 1992\; DeVore et al. 1995\;NJ\; MT\; NH\; JC]"	
"cod-1"	"V"	1.32467	"[C.elegansII] sy193 : males unable to insert spicules during mating. [PS]"	
"cod-2"	"I"	10	"[C.elegansII] sy43 : males unable to insert spicules during mating,spicule muscle defect. [PS]"	
"cod-4"	"III"	-2.027	"[C.elegansII] sy180 : males have difficulty inserting spicules during mating. [PS]"	
"cod-5"	"II"	0.137955	"[C.elegansII] sy181 : males fail to execute proper turning behavior during mating. [PS]"	
"cod-6"	"III"	-0.931184	"[C.elegansII] sy186 : males fail to insert spicules during mating. [PS]"	
"cod-7"	"I"	0.1	"[C.elegansII] sy190 : males unable to insert spicules during mating. [PS]"	
"cod-10"	"I"	8.96214	"[C.elegansII] sy38 : males fail to initiate mating behavior, have a variable tail abnormality which can include abnormal rays, breaks in the alae and occasional pseudovulvae-like structures.  NA1. [PS]"	
"col-2"	"IV"	4.58335	"[C.elegansII] NMK.  Transcript abundant only in dauer larvae. Encodes 300 aa collagen, dpy-13 family (59\%identical to SQT-3). [Kramer et al. 1982\; Cox and Hirsh 1985]"	
"col-3"	"IV"	3.89672	"[C.elegansII] NMK.  Transcript present in all stages, abundant in L4, decreases in adult. [Cox and Hirsh 1985]"	
"col-4"	"IV"	3.50118	"[C.elegansII] NMK.  Misnamed, not a true collagen\; contains 23 repeats of 15 aa sequence GAPPSGGPGPF(D\/N)PS\; no transcript detected. [Cox et al. 1985\; CH]"	
"col-5"	"IV"	5.51184	"[C.elegansII] NMK.  Hybridizes to collagen probe. [Cox et al. 1985]"	
"col-34"	"IV"	0.01	"[C.elegansII] NMK.  Encodes collagen, adjacent and closely related to collagen gene dpy-13. [von Mende et al. 1988\; Bird 1992\; CH]"	
"cul-1"	"III"	2.5	"[C.elegansII] e1756 : normal L1, extra cell divisions in most post-embryonic lineages (about 4-fold increase\; extra cells smaller, but differentiate)\; sterile. ES3 (adult) ME0. NA1. Cloned: encodes predicted 697 aa protein, 28\% identity to yeast CDC53. [Mitani et al. 1993\; NJ]"	
"daf-1"	"IV"	-27.55	"[C.elegansII] m40ts,mat : constitutive dauer formation at 25C, reversible by shift to 15C. Dark intestine\; clumpy.  Exhibits Srf-6 phenotype even at 16C.  ES3 (L3) NA17: n690 (Egl Type C), sa184 (Egl, clumpy)\; many nonconditional alleles eg m65\; e1287, e1146, m402, etc. Cloned: 2.5 kb rare transcript, encodes predicted 669 aa protein with TM domain, cytosolic domain with similarity to raf family Ser\/Thr kinase. [Georgi et al. 1990\; Malone and Thomas 1994\; DR]"	
"daf-2"	"III"	-9.98868	"[C.elegansII] e1370ts : constitutive dauer formation at 25C\; reversible by shift to 15C. Increased lifespanat 20C\; increased thermotolerance, UV resistance. Non-Srf.  Synthetic lethal with daf-12. ES3 (L3). OA>40: e1032, e1286, e1365, sa230 (100\%Daf-c at all temperatures), sa223 (sterile), m65 (nonconditional), etc. Most alleles (not e1370) hypersensitive to dauer pheromone. [Larsen et al. 1995\; Malone and Thomas 1994\; CF\; JC]"	
"daf-3"	"X"	-19.3465	"[C.elegansII] e1376 : defective dauer formation.  ES1 ME3.  OA7. [Riddle et al. 1981\; Thomas et al. 1993\; DR]"	
"daf-4"	"III"	-1.53058	"[C.elegansII] m63ts : constitutive dauer formation at 25C\; reversible by shift to 15C\; at all temperatures small and defective in intestinal endocytosis, similar to Sma-2\; Type E Egl.  Weak maternal rescue.ME0: males have crumpled spicules, fused and displaced rays.ES3 (L3 25C)\; ES2 (other stages). OA7: e1364,m72amb, sa183, sa185, m592ts (ts for Sma) etc\; most alleles resemble m63. Cloned : encodes predicted 744 aa receptor Ser\/Thr kinase, related to activin, TGF-beta receptor kinases. [Estevez et al. 1993\; DR\; JT\; PB\; PJ]"	
"daf-5"	"II"	23.2949	"[C.elegansII] e1386 : defective dauer formation. ES1 ME3. OA11: e1385 etc. [Riddle et al. 1991\; Thomas et al. 1993\; DR]"	
"daf-6"	"X"	19.0906	"[C.elegansII] e1377 : defective dauer formation\; abnormal chemotaxis\; defective osmotic avoidance\; poor male mating\; abnormal sensory anatomy especially amphidial sheath cells (resembles Che-14)\; Dyf, no FITC uptake by amphids or phasmids. ES1 ME2. OA6. [Perkins et al. 1986\; Starich et al. 1995\; DR\; SP]"	
"daf-7"	"III"	-26.1433	"[C.elegansII] e1372ts : constitutive dauer formation at 25C reversible at 15C\; Type C Egl at all temperatures\; dark intestine\; clumpy\;Srf-6 at 16C. ES3 (L3). OA11: m70, m62amb, n696, n708, m434::Tc1,  etc..All alleles Egl and ts Daf. Cloned : encodes novel member of TGFbeta superfamily, possible ligand for DAF-1 receptor. [Golden and Riddle 1984\; \; Thomas et al. 1993\; DR\; JT]"	
"daf-8"	"I"	2.88373	"[C.elegansII] m85ts : constitutive dauer formation at 25C, reversible by shift to 15C\; Type C Egl at all temperatures\; dark intestine\; Srf-6 at 16C.  ES3 (L3). OA7: e1393ts (weak allele), sa233 (Egl, clumpy), etc.Cloned:[Malone and Thomas 1994\; DR\; JT]"	
"daf-10"	"IV"	4.10748	"[C.elegansII] e1387 : defective dauer formation\; abnormal chemotaxis abnormal osmotic avoidance\; males impotent\; abnormal sensory anatomy especially amphidial neurons and sheath cells, cephalic neurons\; Dyf (FITC uptake defective)\; octopamine deficient. ES1. ME0. OA10: m79,  p821 (pka osm-4), m534mut, mn321mut, etc. [Starich et al. 1995\; DR\; SP]"	
"daf-11"	"V"	3.2338	"[C.elegansII] m47ts : constitutive dauer formation at 25C, reversible by shift to 15C\; defective chemotaxis, normal osmotic avoidance\; Odr (defective in response to benzaldehyde, not to diacetyl)\; Srf-6.No effect on lifespan.  Possibly defective in sensing dauer pheromone.  ES3(L3). OA9: m84 (Daf non-Odr), m597::Tc1, sa203 (high penetrance at 15C), etc. Cloned : encodes predicted TM guanyl cyclase. [Riddle et al. 1981\; Vowels and Thomas 1994\; DR\; JT]"	
"daf-12"	"X"	2.13065	"[C.elegansII] m20 : defective dauer formation\; cell migration and lineage defects. ES1 ME3 (ME0 at 25C). OA>20:m25 (pka daf-20), rh84 (distal tip cells fail to reflex, fail to express unc-5:lacZ), etc. At least six phenotypic classes\;some alleles lead to heterochronic defects\; some alleles enhance Age phenotype of daf-2. Cloned : encodes protein similar to nuclear hormone receptors. [Riddle et al. 1981\; Hedgecock et al. 1987\; DR\; NJ]"	
"daf-13"	"X"	-6.3353	"[C.elegansII] m66 : formation of SDS-sensitive dauer larvae. ES1 ME3. NA1. [Riddle et al. 1981\; DR]"	
"daf-14"	"IV"	4.5386	"[C.elegansII] m77ts : constitutive dauer formation at 25C, incomplete penetrance, reversible by shift to 15C\; Type C Egl\; dark intestine\; clumpy\;  Srf-6 at 16C. ES3 (L3). OA1: sa340 (21\% dauers at 25C, derived from egl-21 strain).Cloned: cosmid rescue. [Thomas et al. 1994\; DR\; GR\; JT]"	
"daf-15"	"IV"	4.22838	"[C.elegansII] m81 : constitutive formation of abnormal dauer-like larvae irreversible (genetically lethal)\; does not form true dauers in pheromone. ES3 (L3). OA7. [Albert and Riddle 1988\; DR\; JT]"	
"daf-16"	"I"	5.1	"[C.elegansII] m26 : defective dauer formation. Suppresses Age phenotype of age-1, daf-2. ES1. ME3. OA>10: m27 (pka daf-17), mg11 (possible defect in maintenance of dauer state). [Gottlieb and Ruvkun 1994\; DR\; GR]"	
"daf-18"	"IV"	-25	"[C.elegansII] e1375 : defective dauer formation\; forms some dauer-like larvae when starved.  Partly suppresses Age phenotype of daf-2, age-1.  ES1, ME3. NA1. [Larsen et al. 1995\; DR]"	
"daf-19"	"II"	1.88105	"[C.elegansII] m86ts : constitutive dauer formation at 25C, reversible by shift to 15C\; defective chemotaxis and osmotic avoidance\; Dyf, fails to take up FITC at 15C or 25C\; cilia but not ciliary rootlets missing from sensory neurons. ES3 (L3) ME0. OA5: sa190, sa232,m334 (pka daf-24, nonconditional constitutive formation of dauer larvae.  ES3 (L3)). Cloned: cosmid rescue. [Malone and Thomas 1994\; DR\; JT]"	
"daf-21"	"V"	6.47556	"[C.elegansII] p673ts, mat : constitutive dauer formation\; poor recovery even at low temperature\; defective chemotaxis, defective response to some volatile odorants (benzaldehyde, isoamyl alcohol, like Daf-11)\; normal osmotic avoidance.  Slightly lethargic, semi-sterile at 25C. Strong maternal rescue. p673\/Df is not Daf-c. [Vowels and Thomas 1994\; DR\; JT]"	
"daf-22"	"II"	12.0794	"[C.elegansII] m130 : defective dauer formation (suppressible by exogenous dauer pheromone)\; defective dauer pheromone production. ES1. NA1. [Golden and Riddle 1985\; DR\; JT]"	
"daf-28"	"V"	23.774	"[C.elegansII] sa191ts : constitutive dauer formation\; dauer larvae resume development within 2 hours, even at 25C.  Semidominant: 10\% of sa191\/+ animals form dauers. Probable gf mutation. NA1. [Malone and Thomas 1994]"	
"deb-1"	"IV"	3.28976	"[C.elegansII] st385amb : Pat (paralysed embryonic arrest at 2-fold)\; disorganized muscle\; some pharyngeal pumping.  OA1: st555 (similar).Cloned: encodes dense body component, vinculin. [Barstead and Waterston 1991\; Williams and Waterston 1994]"	
"dec-1"	"X"	17.6759	"[C.elegansII] sa48 : long defecation cycle period, shorter at 25C. [Iwasaki et al. 1995\; JT]"	
"dec-2"	"III"	22.3555	"[C.elegansII] sa89 : long defecation cycle period, slightly slow growing and scrawny\;  appears to feed normally [Iwasaki et al. 1995\; JT]"	
"dec-4"	"IV"	3.25798	"[C.elegansII] sa73 : long defecation cycle period, slightly slow growing and scrawny, reduced brood especially at 25C\; appears to feed normally. [Iwasaki et al. 1995\; JT]"	
"dec-7"	"III"	0.638448	"[C.elegansII] sa92ts, short defecation cycle period at 20C, longer at 25C\;  appears to feed normally OA1: sa296. [Iwasaki et al. 1995\; JT]"	
"dec-9"	"IV"	4.67763	"[C.elegansII] sa293 : short defecation cycle period, semi-dominant\; appears to feed normally. [Iwasaki et al. 1995\; JT]"	
"dec-10"	"X"	1.99184	"[C.elegansII] sa294 : short defecation cycle period, dominant\; appears to feed normally. [Iwasaki et al. 1995\; JT]"	
"dec-11"	"IV"	19	"[C.elegansII] sa292 :  long defecation cycle period, slightly slow growing and scrawny, appears to feed normally [Iwasaki et al. 1995\; JT]"	
"dec-12"	"I"	-10.6995	"[C.elegansII] sa295 : long defecation cycle period, slightly slow growing and scrawny, appears to feed normally [Iwasaki et al. 1995\; JT]"	
"deg-1"	"X"	-1.32723	"[C.elegansII] u38ts,dm : touch-insensitive and prod-insensitive only in tail. PVC interneurons degenerate at L1\/L2, certain other neurons die at hatching (some IL1, also probably AVG) or L4 moult (probably AVD). ES2. OA1 (dominant):u529 (identical). Intragenic revertants (e.g. u38u175) are wildtype (probable null phenotype). Also recessive gf allele: u506 (cs embryonic lethal, arrest at 2-fold with cell degenerations at 15C\; see also des-1, des-4) Cloned: encodes predicted membrane protein, two TM domains surrounding Cys-rich domain.  Deg alleles are A707V (u38, 2nd TM domain) andA393T (u506, predicted extracellular). [Chalfie and Wolinsky 1990\; Hong and Driscoll 1994\; Garcia-Anoveros et al. 1995\; MP\; TU]"	
"deg-3"	"V"	3.15972	"[C.elegansII] u662 : dominant uncoordinated, Tab in tail\; subset of neurons undergo progressive degeneration.  See also des-2, des-3.OA:  > 8 pseudo-wildtype intragenic revertants e.g. u662u692, u662u693 : wild type phenotype. Cloned: encodes alpha subunit of nicotinic acetylcholine receptor, u662 is missense change in second TM domain. [Treinin & Chalfie 1995]"	
"dif-1"	"IV"	3.39822	"[C.elegansII] e2562 : maternal-effect embryonic lethal (mn)\; embryos arrest at the completion of gastrulation with little or no tissue differentiation\; probable null.  OA4:  e2577  (similar), e2591cs (100\% dead eggs at 15C, variably viable and sometimes dumpy at 25C\; TSP hrs 5-8embryo), etc. Cloned: 1.2 kb transcript, present at all stages\;encodes predicted 312 aa protein with similarity to mitochondrial carrier proteins. [Ahringer 1995]"	
"dif-2"	"IV"	4.84633	"[C.elegansII] e2576cs :  maternal effect embryonic lethal (mn)\; embryos arrest at the completion of gastrulation, with little or no tissue differentiation\; e2576 is cold-sensitive, with more differentiation at 25C than 15C, but is inviable at both temperatures.  NA1. [CB]"	
"dig-1"	"III"	-0.939501	"[C.elegansII] n1321 :  gonad displaced, usually to anterior\; 13\% have dorsal gonad\; phenotype enhanced in n1321\/Df. Additional failures of adherence in various tissues, twisted pharynx, defects in ciliated sensory endings\; defective head withdrawal (Not phenotype), normal osmotic avoidance\; similarities to Mig-4.  OA6: n1480, n2467 (Not, defects in CEP, OLQ, AWC,AFD sensory endings\; IL1 and IL2 processes abnormal), nu52, nu336 (severe sensory defects, somewhat Unc, very small brood), nu319ts (weak\; TSP embryonic). [Thomas et al. 1990\; KP\; NJ]"	
"dpy-1"	"III"	-19.4269	"[C.elegansII] el : strong dumpy.  Mosaic analysis indicates focus in hyp7, also required in other hypodermal syncytia. Suppresses some alleles of glp-1.ES3 ME1. OA>20: e6, e830xri, e874pdi, e1177icr,f14, s513 etc. High forward mutation frequency. [Brenner 1974\; Hedgecock and Herman 1995\; EL]"	
"dpy-2"	"II"	0.008233	"[C.elegansII] e8 : dumpy left roller\; early larvae non-dumpy.  Suppresses some alleles of glp-1, emb-5. ES3 ME1. OA>10: e115,  sc38ts, sc78sd,e489 (pka rol-2), e961, q292  etc. Cloned: encodes collagen, 41\% identical to adjacent gene dpy-10. [Brenner 1974\; Levy et al. 1993\; CH]"	
"dpy-3"	"X"	-15.8071	"[C.elegansII] e27 : medium dumpy (non-roller). L1 non-dumpy. Suppresses some alleles of glp-1, emb-5.ES3 (all stages) ME1. OA>10 : e2079, sc26 (left roller dumpy), e182 (pka dpy-12, medium dumpy, ES3 (adult), ME1),  m39ts [Brenner 1974\; EL]"	
"dpy-4"	"IV"	12.4972	"[C.elegansII] e1166sd,icr : large dumpy,  e1166\/+ is slightly dumpy. ES3 (adult) ES1 (larva). ME3. OA1: e1158sd, icr. [Cox et al. 1980\; DR]"	
"dpy-5"	"I"	0	"[C.elegansII] e61 : strong dumpy\; early larvae non-dumpy\; e61\/+ is very slightly dumpy\; homozygote suppressed by Smg, e61\/+ enhanced by Smg. ES3 ME1. OA7: e565, e907pdi, s102, s111fdi, s1300::Tc1, s1706spo. Cloned: encodes novel protein, 257aa, has signal sequence. [Brenner 1974\; Hodgkin et al. 1989\; KR]"	
"dpy-6"	"X"	0	"[C.elegansII] e14 : small dumpy, non-roller. ES3 ME0. OA6: e1502aci, f10, f11, n754 etc. [Brenner 1971]"	
"dpy-7"	"X"	-1.79797	"[C.elegansII] e88 : dumpy (non-roller). Suppresses some alleles of glp-1, emb-5.ES3. ME1. OA>8: e1324ts, sc27ts (left roller dumpy), m38, e2076, q288,  etc. Cloned: transspliced to SL1\;  encodes typical cuticular collagen, 318aa, no close relatives\; 4 missense alleles sequenced\; expressed at each larval stage 5.5 hours pre-lethargus. [Johnstone et al. 1992\; IA]"	
"dpy-8"	"X"	-5.795	"[C.elegansII] e130 : medium dumpy (non-roller) Suppresses some alleles of glp-1, emb-5.ES3. ME1. OA>10: e1281ts, sc24ts (left roller dumpy), sc44, e2279, q287 (weak?), etc. [Brenner 1971\; Maine and Kimble 1989]"	
"dpy-9"	"IV"	-27.8317	"[C.elegansII] e12 : large dumpy. ES3 (adult) ES1 (larvae). ME2. OA3: e424, e858, e1164icr. [Brenner 1974]"	
"dpy-10"	"II"	0	"[C.elegansII] e128 : small dumpy (non-roller)\; sometimes poor survival from freezing\; non-null. Suppresses some alleles of glp-1, emb-5.ES3 (all stages) ME1. OA>10: e223, sc48 (left roller dumpy), sc30ts (pka rol-7, left roller dumpy at 25C),cn64 (dominant left roller), q291, s364fdi etc.Cloned: encodes collagen 41\% identical to DPY-2. e128 is splicing defect, cg36 (left roller dumpy, ochre, probable null). [Brenner 1974\; Levy et al. 1993\; CH]"	
"dpy-11"	"V"	0	"[C.elegansII] e224 : medium dumpy. ES3 (adult) ES2 (larvae). ME2. Males Ram (lumpy rays) at25C.  OA>10: e33, e1180icr (these and most other alleles have much stronger dumpy or 'piggy' phenotype) etc.), e455,e733, e752, s287 (induced on eT1), s10, s261, s360fdi etc. [Brenner 1974\; Baird and Emmons 1990\; CB]"	
"dpy-13"	"IV"	0	"[C.elegansII] e184sd : strong dumpy\; e184\/+ is medium dumpy. ES3 (all stages). ME2. NA13: e458, e1165icr, e225 (pka dpy-16 : recessive medium dumpy), e458, m399::Tc1, e1165, etc. Cloned: encodes 302 aa collagen\; dpy-13 family includes col-2, col-34, sqt-3\; e184 is in-frame deletion, e458 is 673 bp deletion, null, strong dumpy.Expressed at each larval stage, 4 to 2.5 hours pre-lethargus. [Brenner 1974\; von Mende et al. 1988\; CH\; IA]"	
"dpy-14"	"I"	1.40383	"[C.elegansII] e188ts : medium dumpy adult, strong dumpy L1 (20C)\; ts lethal (25C). Lethality enhanced bySmg.   ES3 (all stages 20C). Synthetic lethal with some mutations at 20C. ME2. OA2: n497, s70. Cloned: cosmid rescue. [Brenner 1974\; McKim et al. 1992\; KR\; TR]"	
"dpy-17"	"III"	-2.19971	"[C.elegansII] e164 : medium dumpy, spindle-shaped adult\; old adults sometimes less dumpy\; strong dumpy L1\; low penetrance defects in outgrowth of posterior canal cell processes. ES3 (all stages). ME2. OA6: e1345ts, e905pdi, e1295icr, e1345, e2145 etc. [Brenner 1974\; NJ]"	
"dpy-18"	"III"	8.61813	"[C.elegansII] e364amb : medium dumpy. ES3 (adult) ES2 (larvae). ME2.  Males have abnormal lumpy rays (Ram) at 25C. OA>10: e499, e1270, e1862,s361fdi, s1304 (induced on eT1), bx26 (Ram at 25C), h662. [Brenner 1974\; Baird and Emmons 1990\; PB]"	
"dpy-19"	"III"	-0.166312	"[C.elegansII] e1259ts,des,mat : dumpy (20C, 25C)\; WT (15C)\; abnormal Q and Q daughter migrations.ES3 (adult 25C). Weaker phenotype if mother dpy-19\/+. ME0 (25C) ME3 (15C). OA3: e1314ts, n1347, pk102[DR\; MT\; CF]"	
"dpy-20"	"IV"	5.18354	"[C.elegansII] e1282ts : medium dumpy (20C), weak dumpy (15C), strong dumpy, round-nosed (25C).  TSPduring L1 and L2 stages. ES3 (25C all stages). ME2 (20C). OA>10: other alleles mostly severe round-headed dumpy (20C), inviable or almost inviable (15C), e1362,e1415, cn142 (strongest allele), e2017amb (slightly weaker), cn322, etc. m474::Tc1 : strong dumpy, reverts to Dpy (m474s2033)or wild type (m474m495). Cloned: rare 1.9 kb RNA, most abundant in L2\; encodes predicted 359aa novel protein. [Hosono et al. 1982\; Clark et al. 1995\; BC]"	
"dpy-21"	"V"	13.0144	"[C.elegansII] e428 : weak dumpy (XX)\; non-dumpy (XO)\; lethal to 2A\;3X. ES3 (adult) ES1 (larvae).Some X chromosome transcript levels elevated,in both XX and XO. ME3. OA2: e459 (resembles e428), ct16 (very weak phenotype). [Hodgkin 1983b\; Meyer and Casson 1986\; TY]"	
"dpy-22"	"X"	1.952	"[C.elegansII] e652 : variable, scrawny, dumpy slow-growing (XX)\; very abnormal small or inviable male (XO)\; reduced X chromosome expression. ES2 (all stages XX) ES3 (all stages XO). ME0. NA1. [Meneely and Wood 1987\; Plenefisch et al. 1989]"	
"dpy-23"	"X"	-7.36327	"[C.elegansII] e840 : variable dumpy, head swollen around pharynx, inviable at 15C (XX)\; HSN migrationdefect\; variable QL and DTC Mig defects also\; inviable on low phosphate media\; very abnormal or inviable males (XO). ES2 (XX) ES3 (XO). ME0. OA1: gm17 (similar),[Meneely and Wood 1987\; CB\; BG]"	
"dpy-24"	"I"	5.02122	"[C.elegansII] s71 : weak dumpy\; abnormal DTC migration. ES3 (adult) ES1 (larvae). NA1. [Hedgecock et al. 1987\; BC\; BS]"	
"dpy-25"	"II"	-4.48139	"[C.elegansII] e817sd : strong dumpy, inviable 15C\; e817\/+ is medium dumpy. ES3 (all stages).Intragenic revertants may be wild-type, probable null phenotype.  ME1. NA1. [Hodgkin 1983a\; Chen et al. 1992\; PD]"	
"dpy-26"	"IV"	5.91302	"[C.elegansII] n199mat : XX daughters of n199\/+ mothers are maternally rescued weak dumpy phenotype with protruding vulva (ES2) 4\% Him\; XX daughters of n199\/n199 mothers are severely dumpy and Him (2\% of brood) or die as embryos or young larvae (98\% of XX brood). XO n199 animals are non-dumpy almost wildtype males (ME3). Similar or slightly stronger phenotypes in n199\/Df. OA3: n198 (resembles n199),  y6 (weaker phenotypes), y65. Cloned: encodes predicted 1263 aa novel protein\; antibody staining indicates DPY-26 associated with X chromosomes in XX, diffuse nuclear in XO. [Plenefisch et al. 1989\; TY]"	
"dpy-27"	"III"	-4.40673	"[C.elegansII] rh18mat : XX phenotype is zygotic weak dumpy maternal effect dumpy\/near lethal like Dpy-26 but non-Him. ES2. XO phenotype nearly wildtype male (ME3). OA5: y57 (weaker allele), y44, y42, y56am, y49 (strongest allele). Cloned: encodes 1469 aa protein with similarities to chromosome structural proteins, specifically localized to X chromosomes in XX but not XO animals. [Plenefisch et al. 1989\; Chuang et al. 1994]"	
"dpy-28"	"III"	5.17781	"[C.elegansII] y1mat,ts : at 24C, XX phenotype is zygotic weak dumpy 3\% Him, maternal effect dumpy\/near lethal\; XO phenotype wildtype male (ME3)\; XX viable at 15C, 0.4\% Him. OA1: s939 (non-ts, Him,  >99\% maternal XX lethality at 15C, > 90\% at 20C) . [Plenefisch et al. 1989]"	
"dpy-30"	"V"	3.65	"[C.elegansII] y130 : maternal ts lethal to XX animals, as a result of X chromosome overexpression\;fully penetrant at restrictive temperature (25C). XO animals viable abnormal males: scrawny, slow-growing, mating defective. OA1: y228am. Cloned: 0.6 kb transcript, encodes 123 aa novel protein\; antibody staining indicates DPY-30 ubiquitous nuclear protein, present in both sexes.  Upstream gene in operon with rnp-1. [Hsu and Meyer 1994\; Hsu et al. 1995]"	
"dyf-1"	"I"	-0.516048	"[C.elegansII] mn335mut : defective in dye filling (FITC or DiO) of amphid and phasmid neurons. Chemotaxis defective. ME2. [Starich et al. 1995]"	
"dyf-2"	"III"	21.685	"[C.elegansII] m543mut : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME4 (both alleles).OA1: m160[Starich et al. 1995]"	
"dyf-3"	"IV"	-6.18918	"[C.elegansII] m185 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME4(m185), ME2(mn331), ME1(sa122).  OA2: mn331mut, sa122 [Starich et al. 1995]"	
"dyf-4"	"V"	4.3032	"[C.elegansII] m158 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME4(m158), ME4(m177), ME3(mn332).  OA2: m177, mn332mut. [Starich et al. 1995]"	
"dyf-5"	"I"	3.64399	"[C.elegansII] mn400 :defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Animals slightly short. Chemotaxis defective. ME2 [Starich et al. 1995]"	
"dyf-6"	"X"	1.96744	"[C.elegansII] m175 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME3(m175), ME4(mn346) OA1: mn346mut. [Starich et al. 1995]"	
"dyf-7"	"X"	1.95687	"[C.elegansII] m537mut : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME1 [Starich et al. 1995]"	
"dyf-8"	"X"	12.7333	"[C.elegansII] m539mut : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Animals slightly short. Chemotaxis defective. ME1. [Starich et al. 1995]"	
"dyf-9"	"V"	23.5658	"[C.elegansII] n1513 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME1(n1513), ME3(sa121).  OA1: sa121. [Starich et al. 1995]"	
"dyf-10"	"I"	1.56096	"[C.elegansII] e1383 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME4.  NA1. [Starich et al. 1995]"	
"dyf-11"	"X"	-17.9014	"[C.elegansII] mn392 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Animals slightly short. Chemotaxis defective. ME3. NA1. [Starich et al. 1995]"	
"dyf-12"	"X"	1.94168	"[C.elegansII] sa127 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Chemotaxis defective. ME3.  OA3: nr272, nr2477, nr2344 (dominant Avr allele, heterozygotes98\% non-Dyf but many have less uptake than WT). [Starich et al. 1995]"	
"dyf-13"	"II"	0.232743	"[C.elegansII] mn396 : defective in dye (FITC or DiO) filling of amphid and phasmid neurons. Usually 1-2 amphid neurons dye fill (FITC or DiO). Reduced growth rate and reduced and variable brood sizes. Mildly chemotaxis defective. ME2. NA1. [Starich et al. 1995]"	
"eat-1"	"IV"	4.84164	"[C.elegansII] e2343 : slow, irregular pumping, body slightly long and thin, movement slightly sluggish.  OA1: ad427 (stronger phenotype). [Avery 1993\; DA]"	
"eat-2"	"II"	22.5422	"[C.elegansII] ad465 : medium-strong Eat: slow, often regular pumping. Somewhat hypersensitive to arecoline (cholinergic agonist): most L1s arrested by 5 mM. Lose synaptic transmission from MC motor neuron. OA>10: ad451, ad453, ad459, ad570, ad692.  Complex complementation, 5 classes. [Avery 1993\; DA]"	
"eat-3"	"II"	1.32991	"[C.elegansII] ad426 : generally disgusting worm. Very slow, irregular pumping, sluggish, Egl, dies on recovery from dauer. Strong maternal rescue effect: eat-3 progeny of an eat-3\/+ mother move normally and have only a weak Eat phenotype. NA1. [Avery 1993\; DA]"	
"eat-4"	"III"	0.145806	"[C.elegansII] ad572xri : weak Eat. Normal pumps are interspersed with abnormal pumps in which corpus contractions are feeble but long-lasting, and terminal bulb contractions are long-lasting but of normal strength. Phenotype resembles that caused by killing pharyngeal M3 neurons, but is stronger.  Lacks M3-derived IPSPs. Other behavioral defects: Not, Fab,Che, Ttx\; possibly general defect in glutametergic neurons.OA6: ad537, ad613, ad801, ad818, ad819, ky5. Cloned: encodes possible transporter protein,\"NERD\" family (45\% identity to rat brain phosphate transporter). eat-4:lacZ expressed in multiple neurons. [Avery 1993\; CX\; DA\; KP]"	
"eat-6"	"V"	4.90191	"[C.elegansII] ad467 : strong relaxation-defective.Pharynx oftens fails to relax, or relaxes slowly. There are long yawns, where the corpus stays open for seconds, punctuated with erratic partial relaxations. The terminal bulb is usually more strongly affected than the corpus, but the motions of the two are precisely synchronized. Relaxation transient is reduced in size in electropharyngeograms. Hypersensitive to inhibitors of Na\/K ATPase.  Synthetic lethal with eat-11(ad541).OA2: ad601xri, ad792. Cloned: encodes alpha subunit of Na\/K ATPase (pka spa-1). [Avery 1993\; DA]"	
"eat-7"	"IV"	-16.9789	"[C.elegansII] ad450 : narcoleptic\; eat-7 worms when undisturbed fall \"asleep\"\; tend to become starved. While asleep they do not move or pump, and probably don't defecate. Disturbing them wakes them up, and while awake they act fairly normal. OA1: ad540. [Avery 1993\; DA]"	
"eat-8"	"III"	-25.6111	"[C.elegansII] ad697 : brief, rare pumps. Pumping otherwise normal in Nomarski, except that pumps are sometimes so brief as to be only coordinated twitches. Penetrant, strong Eat. OA1: ad599. [Avery 1993\; DA]"	
"eat-9"	"I"	23.5376	"[C.elegansII] e2337 : slightly starved, irregular pumping. NA1. [Avery 1993\; DA]"	
"eat-10"	"IV"	-28.002	"[C.elegansII] ad606 : strong Eat, slippery isthmus and corpus.NA1. [Avery 1993\; DA]"	
"eat-11"	"I"	2.24653	"[C.elegansII] ad541 : weak Eat: slippery corpus. Slightly long. Movement slightly loopy (i.e. bends are deeper than normal). Hypersensitive to arecoline (cholinergic agonist): will not grown at concentrations >= 1 mM.  Synthetic lethal with eat-6\; suppressed by egl-30(gf), exp-2(gf).  NA1. [Avery 1993\; DA\; JT]"	
"eat-13"	"X"	1.14843	"[C.elegansII] ad522 : strong Eat, slippery pharynx, possible terminal bulb relaxation defect. NA1. [Avery 1993\; DA]"	
"eat-14"	"X"	5.32611	"[C.elegansII] ad573 : medium or weak Eat: grinder sometimes fails to relax fully between pumps. Resembles phm-2 in motion defect, but weaker, and there are no obvious anatomical abnormalities. NA1. [Avery 1993\; DA]"	
"eat-15"	"I"	1.80386	"[C.elegansII] ad602 : medium to weak Eat: slippery isthmus, corpus, and grinder.  NA1. [Avery 1993\; DA]"	
"eat-16"	"I"	3.85344	"[C.elegansII] ad702 : strong Eat: slippery isthmus and corpus. [Avery 1993\; DA]"	
"eat-17"	"X"	23.8245	"[C.elegansII] ad707 : strong Eat: stuffs corpus and isthmus, abnormality in pharyngeal muscles pm6 and pm7 contraction timing. [Avery 1993\; DA]"	
"eat-18"	"I"	23.5682	"[C.elegansII] ad820sd : Eat\; homozygote has slow pharyngeal pumping, lacks I-phase transients in the EPG, and is starved. (ES3). ad820\/+ pumps slower than wild type but faster than ad820\/ad820 and is not very starved (ES1).  OA1. [DA]"	
"egl-1"	"V"	5.865	"[C.elegansII] n487sd,ts : transient bloating Egl\; stimulated by serotonin, not imipramine\;HSN cells undergo programmed cell death hence ced-3 suppressible. No phenotype in male. n487\/+ is ts Egl (penetrance 85\% at 25C, 60\% at 20C). ES2 (adult). ME3. OA3: n986, n987 (both stronger non-ts alleles, n987\/+ penetrance > 95\%), n1084 (weaker than n487). [Ellis and Horvitz 1986\; Desai and Horvitz 1989\; MT]"	
"egl-2"	"V"	-20.2828	"[C.elegansII] n693dm : severe bloating Egl\; stimulated by imipramine, not by serotonin\; weak uncoordinated kinker phenotype. Muscle activation defective (flaccid, long). Defecation defective, Exp (expulsion muscle contraction) nearly always missing\; corrected by imimpramine\; egg-laying and defecation muscles appear normal by polarized light.ES3 (adult) ME1 (abnormal bursal morphology, cloacal structures protrude, poor vulval location\; weak similar phenotype in n693\/+). Probable gf allele.    OA>4: intragenic revertants eg n693n905, n693sa326 (phenotypically wild type).  Also second sd allele, n2656. [Trent et al. 1983\; JT]"	
"egl-3"	"V"	2.32664	"[C.elegansII] n150ts : moderate bloating Egl, stimulated by serotonin and by imipramine\; coiler phenotype. ES3 (adult 25C) ES2 (larvae, males) ME2. OA3: n588 (weakly semidominant), n729. [Trent et al. 1983\; MT]"	
"egl-4"	"IV"	-15.2998	"[C.elegansII] n478 : transient bloating Egl\; variable drug response.  Over-responds to dauer pheromone. ES2 (adult), ME1 (no obvious morphological defect). OA4: n477, n479ts, n579, n612[Trent et al. 1983\; Golden and Riddle 1984]"	
"egl-5"	"III"	-0.549558	"[C.elegansII] n486 : moderate bloating Egl\; stimulated by serotonin, not imipramine\; uncoordinated coiler phenotype\; Mec in posterior\; HSN cell bodies absent or displaced and serotonin-negative\; not suppressed by ced-3. ES3 (adult) ME0. OA>10: e2495, u202, e2399, e2502, e2506,e2508, n1066, n1067, n1439 (weakest allele, males can mate), n945amb (strongest allele), n988, n989. Cloned: encodes Abd-B class homeoprotein (pka ceh-11)[Chisholm 1991\; Wang et al. 1993\; CF\; MT]"	
"egl-6"	"X"	-3.77095	"[C.elegansII] n592sd : transient bloating Egl\;  variable drug response\; uncoordinated weak kinker phenotype. ES2 ME2. NA1. [Trent et al. 1983\; MT]"	
"egl-7"	"III"	-3.21354	"[C.elegansII] n575ts,sd : moderate bloating at 25C, unhealthy\; some bloating at 15C\; stimulated by serotonin and by imipramine. ES2 (adult 25C), ME2 . NA1. [Trent et al. 1983\; MT]"	
"egl-8"	"V"	-20.1177	"[C.elegansII] n488 : transient variable bloating\; variable drug response\; Unc\; Pbo, pBoc defecation contractions weak or very weak. ES2 (adult).  ME0 (variable Mab:fan defective, missing rays).OA5: sa28 (pka pbo-2), sa32ts, sa46 (weaker), sa47. [Trent et al. 1983\; Thomas 1990]"	
"egl-9"	"V"	2.64047	"[C.elegansII] n586ts : transient bloating at 25C\; variable drug response\; resistant to paralysis by toxin from Pseudomonas aeruginosa. ES2 (adult 25C). ME3. OA3: n571 (non-ts), sa307, sa330. [Trent et al. 1983\; MT\; JT]"	
"egl-10"	"V"	4.36868	"[C.elegansII] n692sd,ts : transient bloating, sluggish weak kinker. Type B\/C. HSN appears normal.  Weakly semidominant, partially ts. ES3 (adult). ES2 (other stages). ME2. OA9: n480ts (slight bloating\; stimulated by serotonin and by imipramine), n1068,n1083, n1185 etc. Cloned: predicted protein has distant similarity toyeast signal transduction component, Sst2p. [Trent et al. 1983\; MT]"	
"egl-11"	"V"	3.19118	"[C.elegansII] n587ts : transient bloating at 25C, variable drug response. ES2 (adult 25C). ME2. [Trent et al. 1983\; MT]"	
"egl-12"	"V"	16.1395	"[C.elegansII] n602sd : transient bloating, variable drug response, weakly semidominant. ES2 (adult). ME2. OA1: n599 (recessive). [Trent et al. 1983\; MT]"	
"egl-13"	"X"	-3.715	"[C.elegansII] n483 : penetrance 70\%,  severe bloating or bag-of-worms phenotype (insensitive to serotonin and imipramine)\; minority WT. ES3\/0 (adult) ME3. OA1: e1447. [Trent et al. 1983\; MT]"	
"egl-14"	"X"	-3.58314	"[C.elegansII] n549 : transient bloating. variable drug response. ES2 (adult).  ME0 (no obvious morpho-Mab, poor vulva location). NA1. [Trent et al. 1983\; MT]"	
"egl-15"	"X"	2.48595	"[C.elegansII] n484 : moderate to severe bloating, 60\%form bag-of-worms (insensitive to serotonin, imipramine). Vulval and uterine muscles defective because of defects in sex myoblast migrations. Soc: suppresses and is suppressed by clr-1 mutations.ES3 (adult). ME3.  OA>10: n1458, n1459, ay1 (all 3 resemble n484, Class 1)\; also stronger alleles (Class II, putative null):n1454, n1456, n1478 ( all larval lethal, L1 arrest). Also Class III alleles: n1477ts, n1460, n1780, n1784 (all scrawny, Egl, Soc).  Also Class IV alleles: n1783, n1775 (Soc, no other phenotype).C loned: 4.2 kb transcript, encodes predicted 1040 aa FGFR-type receptor tyrosine kinase.  Transgene over expression leads to Clr phenotype. [Stern and Horvitz 1991\; DeVore et al. 1995\; MT\; NH]"	
"egl-17"	"X"	-19.5567	"[C.elegansII] e1313 : moderate to severe bloating, 30\% form bag-of-worms. insensitive to serotonin and imipramine. Severe posterior displacement of hermaphrodite sex muscles (due to gonadal repulsion)\; enhancer of weak Tra mutation.  Suppressed by clr-1 mutations.ES3 (adult), ME3.  OA9: ay6, n1377, ay10 (putative null)\; all similar. Cloned: cosmid rescue. ay6, n1377 are deletions. [Stern and Horvitz 1991\; Clark et al. 1993\; MT\; NH]"	
"egl-18"	"IV"	-15.5676	"[C.elegansII] n162 : variable bloating, a few form bag-of-worms\; variable drug response\; vulval abnormalities\; low penetrance Vab.  ES3\/1 (adult). ME0(variable Mab, rays blobby or missing, fan abnormal).OA2: n474, n475. [Trent et al. 1983\; MT]"	
"egl-19"	"IV"	3.39812	"[C.elegansII] n582sd : moderate bloating\;  stimulated by imipramine, not by serotonin\; slow and floppy\; long. n582\/Df more severe phenotypes.ES3 (adult) ES2 (other stages). ME1.  NA(lf)>10:st556 (pka pat-5), st576, st577 (all embryonic lethal, severe Pat, probable null phenotype).Also apparent gf alleles: ad695sd (pka eat-12, Weak Eat: terminal bulb stays contracted for longer than normal, sometimes > 1 sec. Corpus action is normal. Muscle hyperactivated, sticky pumping, short,ad695\/+ similar but weaker phenotypes).n2368 (Eat: delayed relaxation and repolarization of terminal bulb\; Egl: eggs of less than 10 nuclei are laid, vulval muscles show spontaneous contraction\; Dpy: may be due to body muscles hypercontraction\; Mab: protruding spicules. n2368\/+ has a phenotype similar to but weaker than n2368. ES3. ME0. n2368 but not n2368\/+ has a cold-sensitive Pat phenotype, penetrant at 12 degree. ME0. Intragenic revertants eg n2368ad979 are recessive Pat) Cloned: may encode calcium channel subunit. [Avery 1993\; Williams and Waterston 1994\; DA\; MT]"	
"egl-20"	"IV"	4.42377	"[C.elegansII] n585ts : moderate bloating at 25C, variable drug response\; pleiotropic Mig, some but not all migrations defective, QL daughters migrate anteriorly.ES3 (adult). ME0 (variable Mab: blobby rays, small fan, displaced sex muscles etc.).NA1. [Trent et al. 1983\; Garriga and Stern 1994\; CF\; MT]"	
"egl-21"	"IV"	4.62637	"[C.elegansII] n611ts : transient bloating at 25C, variable drug response\; partially temperature sensitive\;uncoordinated weak coiler\; abnormal 5-HT signalling. ES2 (adult). ME2. OA2: n476, n576. [Trent et al. 1983\; KP\; MT]"	
"egl-23"	"IV"	10.7869	"[C.elegansII] n601dm : severe bloating (insensitive to serotonin and imipramine)\; some animals form bag-of-worms\; uncoordinated sluggish phenotype (recessive).Vulval muscles contract under laser stimulation. Muscle activation defective (flaccid, long).Defecation defective, slight constipation but almost never have expulsion (Exp)contraction.  ES3 (adult). ES1 (larvae). ME3.OA>4 (intragenic revertants n601sa179 etc : all phenotypically wild type (probable null).  Also second sd allele. [Trent et al. 1983\; JT\; MT]"	
"egl-24"	"III"	-1.06204	"[C.elegansII] n572 : variable bloating (insensitive to serotonin and imipramine)\; some animals WT\; variable Unc and Lon phenotype.ES2 (adult).  ME2. NA1. [Trent et al. 1983\; MT]"	
"egl-25"	"III"	-1.52271	"[C.elegansII] n573 : variable bloating (insensitive to serotonin and imipramine)\; variable abnormal tail morphology. ES2 (adult).  ME0 (no obvious morphological defect).NA1. [Trent et al. 1983\; MT]"	
"egl-26"	"II"	-18.1998	"[C.elegansII] n481 : variable bloating, insensitive to serotonin and imipramine\; 60\% adults form bag-of-worms\; abnormal vulva\; suppressor of Tra-3. ES2 adult.  ME3.   OA1: e1952 (pka egl-48, HME1\/2, stronger suppressor of Tra-3). [Trent et al. 1983\; Hodgkin 1986\; CB\; MT]"	
"egl-27"	"II"	0.120779	"[C.elegansII] n170 : variable bloating, moderate to severe\; variable drug response\; possibly abnormal vulva\; Mig\; males Lin, very abnormal : reduced rays, short spicules, swollen bursa, hermaphroditic tail spike. ES2 (adult). ES3 (adult male).ME0. OA1: e2394. [Trent et al. 1983\; Desai et al. 1988\; CZ\; MT]"	
"egl-28"	"II"	1.60174	"[C.elegansII] n570ts : transient bloating at 25C, variable drug response\; partially temperature sensitive\; Dpy\; ES2 (adult). ME0 (occasional Mab, also variable Spe defect in germ line).  NA1. [Trent et al. 1983\; MT]"	
"egl-29"	"II"	5.09799	"[C.elegansII] n482 : variable,  some animals WT, some animals form bag-of-worms (80\%)\; insensitive to serotonin and imipramine\; variably abnormal vulva (protrusive\; abnormal VU pi fate). ES2 (adult). ME3. NA1. [Trent et al. 1983\; MT\; PS]"	
"egl-30"	"I"	-13.3534	"[C.elegansII] n686sd : moderate bloating,  variable drug response\; Unc slow, very sluggish phenotype, Sma, Gro. Muscle activation defective (flaccid, long).ES3 (adult), ES2 (other stages). ME0 (slight morpho-Mab).  OA>10(dominant): n715sd (uncoordinated paralysed phenotype, n715\/+ has Type C bloating), ad805, ad803, ad806, ad809, ad810 (recessive lethal, flaccid arrest at hatching), ad813, ad814.  The strongest gf alleles are homozygous lethal. Homozygotes hatch, but are paralyzed, with no or feeble contractions of body wall, pharyngeal, and defecation muscles. However, homozygotes move normally during embryonic elongation. Many alleles are dominant suppressors of eat-11. Also intragenic revertants:  n715n1190, n715n1189 (candidate lf: weak Egl, possibly hyperactive), pk45tci. Null phenotype uncertain. Cloned: corresponds to gqa-1, alpha subunit of G protein q (80\% identity to mammalian Gqalpha). [Trent et al. 1983\; Park and Horvitz 1986\; DA\; MT\; PS]"	
"egl-31"	"I"	3.069	"[C.elegansII] n472 : moderate to severe bloating, insensitive to serotonin and imipramine\; some animals formbag-of-worms (20\%) or rupture at vulva\; sex muscles variably defective because of abnormalities in early M lineage\; Unc poor backing phenotype\; Lon?. ES2 (adult) ES2 (other stages).  ME0 (males have M lineage defect also). NA1. [Trent et al. 1983\; CZ\; MT]"	
"egl-32"	"I"	3.95354	"[C.elegansII] n155ts : moderate bloating, variable drug response\;partially temperature-sensitive\; suppressible by daf-3. ES2 (adult). ME3 (some males have abnormal somatic gonads, some have abnormal or feminized germ lines). NA1. [Trent et al. 1983\; MT]"	
"egl-33"	"I"	3.95354	"[C.elegansII] n151ts : moderate to severe bloating at 25C, insensitive to serotonin and imipramine\;some animals form bag-of-worms (40\%) or rupture at vulva\; Gro\;  Unc kinker phenotype at 25C. ES3 (adult 25C), ES2 (larvae 25C). ME2.  NA1. [Trent et al. 1983\; MT]"	
"egl-34"	"I"	-2.41409	"[C.elegansII] n171 : variable bloating, variable drug response\; some animals WT, some form bag-of-worms (10\%). ES2 (adult). ME0 (variable Mab: blobby rays, misshapen bursa, sex muscle defects).  OA1: e1452. [Trent et al. 1983\; CZ\; MT] egl-35III17.53n694ts : transient bloating at 25C\; sensitive to serotonin and to imipramine\; Unc, unhealthy\; precocious HSN differentiation. ES2 (adult 25C). ME3\/ME0(variable Mab: some tail deformity at 25C, less at 20C). NA1. [Trent et al. 1983\; CZ\; MT]"	
"egl-36"	"X"	1.97188	"[C.elegansII] n728dm : severe bloating\; insensitive to serotonin and imipramine\; 50\% adults form bag-of-worms. Abnormal defecation (Exp). Sma? ES2 (adult). Muscle activation defective (flaccid, long).ME3. n728\/+ has similar phenotype. NA1. [Trent et al. 1983\; Park and Horvitz 1986\; JT\; MT]"	
"egl-37"	"II"	1.43134	"[C.elegansII] n742ts : transient bloating at 25C\; variable drug response. ES2 (adult 25C). ME3. NA1. [Trent et al. 1983\; MT]"	
"egl-38"	"IV"	4.58428	"[C.elegansII] n578 : severe bloating\; insensitive to serotonin and imipramine\; almost no egg-laying, >90\% adults form bag-of-worms (>90\%)\; defect in vulval-uterine attachment, persistent survival of AC\;  uncoordinated very sluggish phenotype\; abnormal vulva. ES3 (all stages). OA2: sy294 (pka lin-50, males have abnormal tails with U and B lineage defects\; hermaphrodites also have abnormal tails, frequently sterile), s1775. [Trent et al. 1983\; MT\; PS]"	
"egl-40"	"IV"	4.33029	"[C.elegansII] n606ts,sd : transient bloating\; sensitive to serotonin and to imipramine\; partially temperature sensitive\; Dpy.  Over-responds to dauer pheromone.ES2 (adult 25C). ME3. NA1. [Trent et al. 1983\; Golden and Riddle 1984\; MT]"	
"egl-41"	"V"	5.70244	"[C.elegansII] n1077cs sd : moderate bloating, sensitive to serotonin and not to imipramine\; HSN cells absent in adult (ced-3 suppressible)\; other indications of weak masculinization of XX animals (CEM cells survive\; weak suppressor of tra-2(gf)). Also XO animals sometimes weakly feminized, especially at 25C.  . Penetrance of n1077\/+ XX : 60\% Egl at 20C. ES2 (adult). ES1 (other stages). OA3: n1069, n1074, e2055 (all similar). [Desai and Horvitz 1989\; Hodgkin et al. 1985\; CB\; MT]"	
"egl-42"	"II"	0.324613	"[C.elegansII] n995sd : moderate bloating\; stimulated by serotonin, not imipramine\; HSN appear normal\; slight bloating in n995\/+. ES2 (adult). ME2. OA1 (n996sd). [Desai and Horvitz 1989\; MT]"	
"egl-43"	"II"	1.82884	"[C.elegansII] n997 : moderate bloating\; stimulated by serotonin, not imipramine. HSN cell bodies serotonin-positive but misplaced posteriorly along path of HSN migration\; aberrant variable HSN processes\; abnormal IL2 wiring. ES2 (adult) ES1 (other stages). ME2.  OA1: n1079. Cloned: 2.5 and 1.8 kb transcripts, encode 517 aa or360 aa zinc finger proteins, related to mouse Evi-1. [Desai and Horvitz 1989\; Garriga and Stern 1994\; KP\; MT\; NG]"	
"egl-44"	"II"	-1.74541	"[C.elegansII] n998 : moderate bloating\; stimulated by serotonin, not imipramine\; HSN cell bodies do not contain serotonin\; axon defects\; slow growth.  Serotonin levels increased if synapse formation blocked.  Ectopic expression of mec-7. ES2 (adult). ME2.  OA2: n1080, n1087 (strongest allele). [Desai and Horvitz 1989\; MT\; TU]"	
"egl-45"	"III"	-0.547216	"[C.elegansII] n999 : moderate bloating\;  stimulated by serotonin, not imipramine\;  HSN cell bodies sometimes degenerate in L4,  absent in adult and never contain serotonin\; Unc\;axon defects\; some sterility.  n999\/Df often very unhealthy, slow, sterile.  HSN degeneration is suppressed by unc-76 and unc-42 mutations.ES2 (adult) ES1 (other stages).  ME1 (variable morpho-Mab: posterior bulges in fan, some spicule and muscle defects).  NA1. Cloned: encodes novel predicted protein. [Desai and Horvitz 1989\; MT]"	
"egl-46"	"V"	0.195	"[C.elegansII] n1127 : moderate bloating\; stimulated by serotonin, not imipramine\; HSN cell bodies do not contain serotonin\; torpid Unc and Lin (abnormal Q lineage) phenotypes\; axon defects\; serotonin levels increased if HSN synapse formation blocked.  Ectopic expression of mec-7. n1127\/Df similar. ES2 (adult) ES1 (other stages). ME2. OA3: n1075, n1076. [Desai and Horvitz 1989\; MT\; TU]"	
"egl-47"	"V"	2.56685	"[C.elegansII] n1081dm : moderate bloating\; stimulated by serotonin, not imipramine. HSN appear normal.  Slightly Unc, kinking tendency.  Probable gf allele.ES2 (adult).  ME2.   OA1: n1082dm. [Desai and Horvitz 1989\; MT]"	
"egl-50"	"II"	23.4635	"[C.elegansII] n1086cs : Egl\; stimulated by serotonin, not imipramine\; HSN appear normal\; slight Dpy\; weak Tra (some intersexes at 15C)\; weak Him.ME2. [Desai and Horvitz 1989\; MT]"	
"ego-1"	"I"	2.07131	"[C.elegansII] om18 : recessive enhancer of glp-1(bn18) at 20C\; has reduced germ cell number, 50\% of wild type in young adult, delayed spermatogenesis, abnormal unfertilized oocytes. NA1. [Qiao et al. 1995\; EL]"	
"ego-2"	"I"	7.57313	"[C.elegansII] om33 : recessive enhancer of glp-1(bn18) at 20C, also interacts with glp-4(om14). NA1. [Qiao et al. 1995\; EL]"	
"ego-3"	"V"	6.39533	"[C.elegansII] om40 : recessive enhancer of glp-1(bn18) at 20C, reduced germ cell number, 50\% of WT in young adult, delayed spermatogenesis\; some proximal germline proliferation\; abnormal unfertilized oocytes, some somatic gonad abnormalities\; severe Unc as larva, not as adult. NA1. [Qiao et al. 1995\; EL]"	
"ego-4"	"III"	0.835144	"[C.elegansII] om30 : recessive enhancer of glp-1(bn18) at 20C, reduced germ cell number, 30\% of WT in young adult, defective oocytes (Mel, usually mid-embryonic arrest).  OA1: om60. [Qiao et al. 1995\; EL]"	
"ego-5"	"III"	0.705882	"[C.elegansII] om31 : recessive enhancer of glp-1(bn18) at 20C, reduced germ cell number, 30\% of WT in young adult, defective oocytes (Mel, late embryonic arrest).  OA1: om62. [Qiao et al. 1995\; EL]"	
"elt-1"	"IV"	4.35909	"[C.elegansII] zu180 : zygotic recessive lethal, makes no hypodermis, extra cell divisions in all hypodermal lineages, extra neuron-like cells.  OA1: pk60 (Tc1 insertion, no known phenotype). Cloned: 1.7 kb transcript, transpliced to SL1, encodes GATA family protein, functional in yeast. Transcripts most abundant in germ line, especially male\; elt-1:lacZ expressed in embryo from 50-cellstage. [Spieth et al. 1991\; BL\; JJ\; JM]"	
"emb-1"	"III"	-4.65884	"[C.elegansII] hc57ts,mm : at 25C one to 24 cell arrest no pseudocleavage defective cytoplasmic streaming. Normal and defective execution before one cell stage. Viable at 16C. OA1: hc62ts (similar phenotype). [Miwa et al. 1980\; MJ]"	
"emb-2"	"III"	-4.96509	"[C.elegansII] hc58ts,mnz : at 25C lima bean arrest\; abnormal blastocoel\; division rates slowed about 20\%. Normal execution in oogenesis or early cleavage\; defective execution later. Viable at 16C slightly slow divisions. NA1. [Miwa et al. 1980\; MJ]"	
"emb-3"	"IV"	3.71403	"[C.elegansII] hc59ts,mm : at 25C lima bean arrest\; early nuclear and cytoplasmic abnormalities abnormal blastocoel\; division rates slightly faster. Normal and defective execution before fertilization. NA1. [Miwa et al. 1980\; MJ]"	
"emb-4"	"V"	21.0503	"[C.elegansII] hc60ts,mm : at 25C lima bean arrest\; slow division rates especially E lineage. Shift to 25C in L1 results in defective gonadogenesis. At 16C subviable : 60\% of eggs fail to hatch many larvae die or have gross morphological abnormalities.  NA1. [Miwa et al. 1980\; MJ]"	
"emb-5"	"III"	-2.93066	"[C.elegansII] hc61ts,mm : at 25C lima bean arrest misplaced gut granule birefringence\; abnormal gastrulation division rates slowed (except E lineage, precocious) Ea divides a\/p. Normal and defective execution at 24 cell stage. Shift to 25C in L1 results in defective gonadogenesis. Viable at 16C. Suppressible by mutations in dpy-2,3,7,8,10.OA3: g16ts, g65ts (similar to hc61), hc67ts (division rates faster than WT, otherwise like hc61). Cloned: 5.4 kb transcript, encodes predicted 1521 aa protein, some similarity to yeast nuclear protein SPT6[Miwa et al. 1980\; Denich et al. 1984\; MJ]"	
"emb-6"	"I"	-0.475063	"[C.elegansII] hc65ts,mm : at 25C 14 cell arrest, no gut granule birefringence\; division rates very slow. Normal and defective execution before first cleavage. Viable at 16C. OA1: g36ts (similar). [Miwa et al. 1980\; Denich et al. 1984\; MJ]"	
"emb-7"	"III"	-2.93297	"[C.elegansII] hc66ts,mm : at 25C lima bean arrest division rates slightly slowed. Normal and defective execution before first division. At 16C viable but slightly abnormal division rates. OA2: b84ts (pka zyg-4 : 25C embryonic arrest <100 nuclei\; L1 temperature shift-up affects gonadogenesis), b64. [Miwa et al. 1980\; MJ]"	
"emb-8"	"III"	-4.27723	"[C.elegansII] hc69ts,mm : at 25C eggs osmotically sensitive, variable arrest (early to mid-cleavage) division rates slowed. At 16C viable but eggs are fragile. NA1. Cloned: cosmid rescue (ZC235). [Miwa et al. 1980\; MJ]"	
"emb-9"	"III"	0.489382	"[C.elegansII] hc70sd,ts,nn : at 25C early pretzel arrest, a few animals hatch and die in L1\; ts for larval growth (arrest shortly after any shift to 25C). Normal and defective execution in late embryogenesis. OA>10:g23ts, g34ts, b117ts, b189ts (pka zyg-6))(all similar to hc70), mj70ts (Mig, abnormal Q daughter migration).Also Pat alleles: st540, st545 (paralysed arrest at two-fold, late paralysis, no elongation).Putative nulls recessive, arrest at 3-fold stage\; strong missense alleles arrest at 2-fold. Cloned: pka clb-2, encodes  1758 aa basement membrane collagen (Type IV), alpha1 chain. [Denich et al. 1984\; Sibley et al. 1993\; CH\; MJ\; RW]"	
"emb-10"	"I"	1.7628	"[C.elegansII] hc63ts : embryonic arrest.OA1: k12ts (sterile\; viable at 16C). [MJ]"	
"emb-11"	"IV"	4.74416	"[C.elegansII] g4ts,mm : osmotically sensitive eggs at 25.6C (leaky at 25C), 94\% arrest during early proliferation\; escapers mostly arrest in L1. Temperature shift-up in L1 or L4 results in abnormal gonadogenesis. Adults dumpy at 25C, uncoordinated at 16C. OA1: g1ts (similar phenotypes but lower penetrance). [Cassada et al. 1981\; RC]"	
"emb-12"	"I"	2.06452	"[C.elegansII] g5ts,mm : osmotically sensitive eggs at 25.6C (leaky at 25C), 72\% arrest during early proliferation\; escapers have abnormal gonads. Temperature shift-up in L1 results in incompletely penetrant gonad defects. Viable at 16C. NA1. [Cassada et al. 1981\; RC]"	
"emb-13"	"III"	-11.7373	"[C.elegansII] g6ts,nm : at 25C 99\% eggs arrest at lima bean, no gut granule birefringence. Reduced cytoplasmic streaming before first cleavage slow divisions\; E D and P lineages early. Escapers arrest as larvae abnormal gonadogenesis\; L1 temperature shift-up results in larval arrest, abnormal gonad. At 16C viable variably long. NA1. [Cassada et al. 1981\; Denich et al. 1984\;  RC]"	
"emb-14"	"I"	1.68267	"[C.elegansII] g43ts,nm : osmotically sensitive eggs at 25C 100\% eggs arrest during proliferation. Escapers arrest as larvae\; L1 temperature shift-up results in some gonad abnormality. At 16C viable poor male mating. OA1: g14ts,mm? (similar phenotypes, lower penetrance). [Cassada et al. 1981\; RC]"	
"emb-15"	"X"	7.48823	"[C.elegansII] g15ts,mnz : at 25C 97\% eggs arrest at pretzel\; prolonged mitoses during cleavage. Escapers arrest L1-L4. Viable 16C. NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-16"	"III"	-0.774836	"[C.elegansII] g19ts,mm : at 25C 91\% eggs arrest at lima bean misplaced gut granule birefringence. E lineage early MS delayed. Escapers arrest in L1 abnormal gonadogenesis. L1 temperature shift-up affects gonadogenesis. At 16C viable, somewhat uncoordinated.NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-18"	"V"	2.20389	"[C.elegansII] g21ts,mm : at 25C 100\% eggs arrest at lima bean, normal gut granule birefringence\; eggs variably round in shape. C and E lineages late, P4 early. Escapers arrest L2-L4. L1 temperature shift-up affects gonadogenesis. At 16C slightly long. NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-19"	"I"	2.06452	"[C.elegansII] g22ts,mm : osmotically sensitive eggs at 25C, 100\% arrest during early proliferation. Escapers arrest L1-L4. L1 temperature shift-up affects gonadogenesis. At 16C viable. NA1. [Cassada et al. 1981\; RC]"	
"emb-20"	"I"	13.312	"[C.elegansII] g27ts,mm : osmotically sensitive eggs at 25.6C (leaky at 25C) 96\% arrest during early proliferation. Escapers viable F1 Emb. At 16C viable. OA1: g26[Cassada et al. 1981\; RC]"	
"emb-21"	"II"	0.595074	"[C.elegansII] g31ts,mm : at 25C 90\% eggs arrest 26-30 cell stage no gut granule birefringence\; variable round eggs\; large ooplasmic granules prolonged mitoses especially AB. Escapers arrest L2-L3 abnormal gonadogenesis. L1 temperature shift-up affects gonadogenesis. NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-22"	"V"	1.28683	"[C.elegansII] g32ts,nm : at 25C 100\% eggs arrest at lima bean, misplaced gut granule birefringence. Strong ooplasmic streaming, erratic pronuclear migration, no polar body formation, all mitoses prolonged. Temperature shift- up at all stages after lima bean results in immediate arrest. At 16C viable. NA1. Tightly linked to and possibly identical with act-123. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-23"	"II"	2.94886	"[C.elegansII] g39ts,mm : at 25C 100\% eggs arrest at lima bean, misplaced gut granule birefringence. Very large ooplasmic granules\; MS, C and P2 divisions late. Escapers arrest L1-L2 abnormal gonads. L1 temperature shift-up results in L1-L2 arrest abnormal gonads. At 16C viable. NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-24"	"III"	0.031765	"[C.elegansII] g40ts,mnz : at 25C 100\% eggs arrest at pretzel, normal gut granule birefringence. E lineage late. L1 temperature shift-up results in L1-L3 arrest. At 16C viable but many defective embryos. NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-25"	"III"	-0.377475	"[C.elegansII] g45ts,mm : at 25C 100\% eggs arrest at 100-250 cells, normal gut granule birefringence\; eggs variably long in shape. Later divisions slow or incomplete. Escapers arrest L1-L2. L1 temperature shift-up results in L1-L2 arrest. At 16C viable. NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-26"	"IV"	2.45126	"[C.elegansII] g47ts,mm : at 25.6C (leaky at 25C) 80\% eggs arrest at lima bean, abnormal gut granule birefringence. Slow ooplasmic streaming cleavage timing alterations. Escapers arrest L1-L4 abnormal gonads. L1 temperature shift-up affects gonadogenesis. At 16C viable, slightly long, poor male mating. Meiotic phenotype at 20C (pka him-12), self-progeny 8\% XO male, low brood size (65\% unhatched eggs), males sire many inviable zygotes. ES3 (progeny) ME2. NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-27"	"II"	0.78789	"[C.elegansII] g48ts,mm,pat : at 25C 100\% eggs arrest at one cell stage. No polar body formation, no pseudocleavage, 30\% fail to reform pronucleus\; pronuclear migration and fusion are slow or absent, pronuclei disintegrate. Escapers viable adults F1 Emb. Males crossed with wildtype hermaphrodites sire progeny that arrest at 100 cell stage\; mutant hermaphrodites crossed with WT males also produce embryos arrested at 100 cell stage. Pleiotropic defect in gametogenesis (compare emb-30). L1 temperature shift-up results in viable adult F1 Emb. At 16C viable. NA1. [Cassada et al. 1981\; Denich et al. 1984\; DS\; RC]"	
"emb-28"	"V"	13.9078	"[C.elegansII] g49ts,mm : at 25.6C (leaky at 25C) 91\% arrest at lima bean, misplaced gut granule birefringence. Very large ooplasmic granules\; slow and abnormal first cleavage\; later divisions slow. Escapers viable with abnormal gonad. L1 temperature shift-up results in viable adult F1 Emb. At 16C viable. NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-29"	"V"	-18.3914	"[C.elegansII] g52ts,nn : at 25C 100\% eggs arrest before mitosis during 150-200 cell stage\; misplaced gut granule birefringence. Some divisions delayed. Escapers arrest L2-L4. L1 or L4 temperature shift-up affects gonadogenesis. Probably general G2\/M cell cycle arrest. At 16C viable. OA4: b262 (similar phenotypes), s819, s1613, s1666fdi. Cloned: cosmid rescue?[Denich et al. 1984\; Hecht et al. 1987\; BC\; HH]"	
"emb-30"	"III"	0.995325	"[C.elegansII] g53ts,mm,pat : round osmotically sensitive eggs at 25Cx\; 96\% eggs arrest at one cell stage. Ooplasmic streaming somewhat abnormal, only one polar body\; no pseudocleavage\; no pronuclear migration or fusion\; some endomitosis. Escapers are viable adults F1 Emb. Males crossed with WT hermaphrodites sire progeny that arrest at 100-cell stage.  Pleiotropic defect in gametogenesis? (compare emb-27). L1 temperature shift-up results in viable adult F1 Emb. At 16C viable slightly uncoordinated. NA1. Cloned: cosmid rescue.  Operon includes tbg-1, so emb-30 may correspond to tbg-1. [Cassada et al. 1981\; Denich et al. 1984\; RC \; SQ]"	
"emb-31"	"IV"	2.89695	"[C.elegansII] g55ts,mm : at 25C 100\% eggs arrest at lima bean, normal gut granule birefringence. Abnormal blastocoel and gastrulation. Escapers sometimes arrest in L1-L2, abnormal gonads. L1 temperature shift-up affects gonadogenesis. At 16C viable. NA1. [Cassada et al. 1981\; RC]"	
"emb-32"	"III"	-6.65367	"[C.elegansII] g58ts,mnz : at 25.6C (leaky at 25C) 97\% eggs arrest at lima bean, normal gut granule birefringence. Ooplasmic streaming slow, cleavage timing altered, late divisions slow. Escapers arrest in L2. L1 temperature shift-up results in L2 arrest abnormal gonadogenesis. At 16C viable dumpy. NA1. [Cassada et al. 1981\;  Denich et al. 1984\; RC]"	
"emb-34"	"III"	0.290587	"[C.elegansII] g62ts,nm : at 25C 100\% eggs arrest at lima bean, abnormal gut granule birefringence\; egg shape variable. Some pseudocleavage failure, erratic pronuclear migration\; first mitosis prolonged\; later divisions prolonged and skewed. L1 temperature shift-up results in L1 arrest. At 16C viable. NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emb-35"	"IV"	0.258039	"[C.elegansII] g64ts,mnz : at 25.6C (leaky at 25C) 97\% eggs arrest at lima bean, normal gut granule birefringence. Later divisions delayed and prolonged,  P4 early. Escapers small, arrest L1-L4. L1 temperature shift-up results in some larval arrest, dumpy adults F1 Emb. At 16C viable. NA1. [Cassada et al. 1981\; Denich et al. 1984\; RC]"	
"emo-1"	"V"	2.83814	"[C.elegansII] oz1 : oocyte diakinesis arrest defective. Hermaphrodite sterile. In hermaphrodite, unfertilized oocytes in diakinesis undergo DNA endoreduplication and become polyploid.  OA1: oz151 (embryonic lethal). Cloned : cosmid F32D8[BS]"	
"epi-1"	"IV"	4.72	"[C.elegansII] rh165 : basal lamina missing or defective in epidermis, gonad, intestine\; pharynx normal\; some migrations defective\; body wall myofilaments disorganized\; uterus and spermatheca fail to epithelialize, release proliferating germ cells\; sterile.  OA3: rh152 (weaker allele, mostly sterile), gm1, gm80 (more severe?). Cloned: encodes predicted protein with similarity to  laminin A (pka lgx-3). [NJ\; GS\; NG]"	
"evl-1"	"V"	2.4196	"[C.elegansII] ar115 : everted vulva, sterile\; normal L4 vulval invagination, abnormal uterus, abnormal oocytes. NA1. [Seydoux et al., 1993]"	
"evl-2"	"II"	-2.17962	"[C.elegansII] ar119 : everted vulva, sterile\; normal L4 vulval invagination\; abnormal uterus, abnormal oocytes. NA1. [Seydoux et al., 1993]"	
"evl-3"	"II"	1.90043	"[C.elegansII] ar99 : everted vulva, sterile\; normal L4 vulval invagination, no uterine cavity, abnormal distal germ line, no sperm or oocytes.  OA2: ar100, ar118 (both similar). [Seydoux et al., 1993]"	
"evl-4"	"II"	2	"[C.elegansII] ar101 : everted vulva, sterile\; abnormal L4 vulval invagination, abnormal uterus, abnormal oocytes.   OA1: ar116 (similar). [Seydoux et al., 1993]"	
"evl-5"	"V"	-0.410124	"[C.elegansII] ar105 : everted vulva, sterile\;  abnormal L4 vulval invagination, abnormal uterus, abnormal oocytes. NA1. [Seydoux et al., 1993]"	
"evl-6"	"IV"	6	"[C.elegansII] ar120 : everted vulva, sterile\;  abnormal L4 vulval invagination, abnormal uterus, abnormal oocytes. NA1. [Seydoux et al., 1993]"	
"evl-7"	"IV"	1.73536	"[C.elegansII] ar108 : everted vulva, sterile\;  abnormal L4 vulval invagination, abnormal uterus, no oocytes.  NA1. [Seydoux et al., 1993]"	
"evl-8"	"III"	1	"[C.elegansII] ar102 : everted vulva (or sometimes no vulval induction), sterile\;  abnormal L4 vulval invagination, abnormal uterus, abnormal oocytes.  NA1. [Seydoux et al., 1993]"	
"evl-9"	"I"	3	"[C.elegansII] ar121 : everted vulva, sterile\; abnormal L4 vulval invagination\; abnormal uterus\; distal germ line abnormal\; abnormal oocytes\; no sperm.  NA1. [Seydoux et al., 1993]"	
"evl-10"	"I"	1.02162	"[C.elegansII] ar95 : everted vulva, sterile\; abnormal L4 vulval invagination\; abnormal uterus\; distal germ line abnormal\; no sperm or oocytes.  NA1. [Seydoux et al., 1993]"	
"evl-11"	"V"	-0.820247	"[C.elegansII] ar114 : everted vulva, sterile\; abnormal L4 vulval invagination\; no uterine cavity\; abnormal oocytes.  OA1: ar113 (similar). [Seydoux et al., 1993]"	
"evl-12"	"V"	3.23978	"[C.elegansII] ar109 : everted vulva (or sometimes no vulval induction)\; sterile\; abnormal L4 vulval invagination\; no uterine cavity\; abnormal oocytes.   NA1. [Seydoux et al., 1993]evl-13IV3.3ar107 : everted vulva, sterile\; abnormal L4 vulval invagination\; no uterine cavity\;no oocytes.  NA1. [Seydoux et al., 1993]"	
"evl-13"	"IV"	3.3	"[C.elegansII] ar107 : everted vulva, sterile\; abnormal L4 vulval invagination\; no uterine cavity\;no oocytes.  NA1. [Seydoux et al., 1993]"	
"evl-14"	"III"	-3.09883	"[C.elegansII] ar96 : everted vulva, sterile\; no L4 vulval invagination\; abnormal uterus and oocytes.OA2: ar97, ar112 (both similar)[Seydoux et al., 1993]"	
"evl-15"	"IV"	-4	"[C.elegansII] ar126 : everted vulva, sterile\; no L4 vulval invagination\; abnormal uterus\; no oocytes.NA1. [Seydoux et al., 1993]"	
"evl-16"	"I"	3	"[C.elegansII] ar93 : everted vulva, sterile\; no L4 vulval invagination\; abnormal uterus and oocytes\; distal germ line abnormal.  NA1. [Seydoux et al., 1993]"	
"evl-17"	"I"	3	"[C.elegansII] ar94 : everted vulva, sterile\; no L4 vulval invagination\; abnormal uterus and oocytes\; distal germ line abnormal.  NA1. [Seydoux et al., 1993]"	
"evl-18"	"III"	-7	"[C.elegansII] ar117 : everted vulva, sterile\; no L4 vulval invagination\; abnormal uterus\; distal germline abnormal, no sperm or oocytes.  NA1. [Seydoux et al., 1993]"	
"evl-19"	"III"	1	"[C.elegansII] ar98 : everted vulva, sterile\; no L4 vulval invagination\; abnormal uterus\; distal germline abnormal, no sperm or oocytes.  NA1. [Seydoux et al., 1993]"	
"evl-20"	"II"	0.92015	"[C.elegansII] ar103 : everted vulva, sterile\; no L4 vulval invagination\; abnormal uterus\; distal germline abnormal, no sperm or oocytes.  NA1. [Seydoux et al., 1993]"	
"evl-21"	"III"	-7	"[C.elegansII] ar122 : everted vulva (or sometimes no vulva), sterile\; no L4 vulval invagination\; abnormal uterus\; distal germ line abnormal, no sperm.  NA1. [Seydoux et al., 1993]"	
"evl-22"	"II"	3	"[C.elegansII] ar104 : everted vulva, sterile, no L4 vulval invagination\; no uterine cavity\; no sperm or oocytes.  NA1. [Seydoux et al., 1993]"	
"evl-23"	"IV"	3.26248	"[C.elegansII] ar106 : everted vulva (or sometimes no vulva), sterile, no L4 vulval invagination\; no uterine cavity\; abnormal oocytes.  NA1. [Seydoux et al., 1993] evl-24IV4ar124 : everted vulva, sterile, no L4 vulval invagination, no uterine cavity or oocytes\; distal germ line abnormal. NA1. [Seydoux et al., 1993]"	
"evl-24"	"IV"	4	"[C.elegansII] ar124 : everted vulva, sterile, no L4 vulval invagination, no uterine cavity or oocytes\; distal germ line abnormal. NA1. [Seydoux et al., 1993]"	
"exc-1"	"X"	21.2401	"[C.elegansII] rh26 : excretory canal defect. Large vacuoles appear randomly along the excretory canal, especially at the tips. 100\% penetrant. Often visible by low-power microscopy.  NA1. [NJ]"	
"exc-2"	"X"	-5.44737	"[C.elegansII] rh90 : excretory canal defect. Canals are very short and consist of a series of vacuoles. Luminal coat partly detached, floats in canal.100\% penetrant.Usually visible by low-power microscopy.  Affects tail spike ??? OA1: rh105. [NJ]"	
"exc-3"	"X"	1.15316	"[C.elegansII] rh186 : excretory canal defect. Canals are shortened and animal is somewhat pale. Defect visible only by Nomarski microscopy. OA1: rh207. [NJ]"	
"exc-4"	"I"	25.3871	"[C.elegansII] rh133 : excretory canal defect. Vacuolesappear in canal during embryogenesis, and drastically shorten canal by hatch. Animals are pale, slightly unc, and are often killed by growth of large vacuoles at the excretory cell body. Defect visible by low-power microscopy. Affects tail spike ??? OA1: n2400[NJ]"	
"exc-5"	"IV"	4.34733	"[C.elegansII] rh232 : excretory canal defect. Large vacuoles appear randomly along the excretory canal. 100\% penetrant.Often visible by low-power microscopy.  OA2: n2669 (weaker allele, smaller vacuoles), n2672. [NJ]"	
"exc-6"	"III"	-24.5466	"[C.elegansII] rh103 : excretory canal defect. Canal varies in length from no outgrowth to almost complete outgrowth. Frequent small vacuoles and extrabranchings in the canal lumen visible only by Nomarski microscopy. Animal is somewhat pale. NA1,[NJ]"	
"exc-7"	"II"	1.59579	"[C.elegansII] rh252 : excretory canal defect. Canal is invariably short with multiple cysts of varying size clustered along length, especially at the tips.  Visible only by Nomarski microscopy. Animal is somewhat pale.  NA1. [NJ]"	
"exp-1"	"II"	-0.887555	"[C.elegansII] sa6 : severe to moderate constipation, Exp contraction present about every sixth cycle, slight Egl\; defecation phenotype resembles Unc-25, Unc-47\; GABA staining normal\;  sa6\/Df similar.  NA1. [Thomas 1990\; JT]"	
"exp-2"	"V"	-0.23476	"[C.elegansII] sa26sd : recessive lethal\; sa26\/+ strongly dominant,severely constipated, jerky Unc\;expulsion muscle contraction (Exp) always absent from defecation cycle, severe egg laying defect (Type A Egl), serotonin nonresponsive, egg laying and anal muscle normal as observed by polarized light, pumping very shallow but rapid.  Muscle activation defective (flaccid, long).  NA1 (gf).Intragenic revertants, eg sa26sa66, sa26sa68, arerecessive lethal, no dominant Exp phenotype. [Thomas 1990\; JT]"	
"exp-3"	"V"	21.72	"[C.elegansII] n2372sd :  semi-dominant, severely bloated egg-laying defective (Type A). Frequently forms bag-of-worms. Also semi-dominantly defective for expulsion step of defecation. Rarely has expulsion (Exp). Severely constipated. Egg-laying and enteric muscles grossly normal by polarized light microscopy. Muscle activation defective (flaccid, long).ES3 (adult). ES2 (larvae). ME3. NA1. [Reiner et al. 1995, JT]"	
"exp-4"	"IV"	-4.99544	"[C.elegansII] m2373sd : semi-dominant, moderately bloated egg-laying defective (Type A). Infrequently forms bag-of-worms. Also semi-dominantly defective for expulsion step of defecation. Infrequently has expulsion (Exp). Moderately constipated. Egg-laying and enteric muscles grossly normal by polarized light microscopy. Muscle activation defective (flaccid, long). ES3 (adult). ES2 (larvae). ME3.  NA1 [Reiner et al. 1995, JT]"	
"fem-1"	"IV"	1.96617	"[C.elegansII] e1965mat : XO animals transformed into fertile females if mother homozygous, into intersexes if mother heterozygous. XX animals females if mother homozygous, femalesor hermaphrodites if mother heterozygous. Null allele. ES3 (XO adult) ES2 (XX adult) ME0. OA>20: e1991amb (resembles e1965), e1949, etc.\; also many ts alleles, hc17ts (pka isx-1, causes only partial XO feminization at 25C, XX self fertile at 20C), e1918ts, e1988ts, e1973ts. Cloned : 2.4 kb transcript, encodes 656 aaprotein with 6 ANK repeats. Antibody staining indicates present in both sexes, both germline and soma. [Doniach and Hodgkin 1984\; Spence et al. 1990\; AS]"	
"fem-2"	"III"	-26.7673	"[C.elegansII] e2105ts,mat : XO animals transformed into fertile females (25C) or intersexes (20C) if mother homozygous, into abnormal males if mother heterozygous\; XX animals fertile females if mother homozygous hermaphrodite if mother heterozygous\; XX phenotype non-ts. ES3 (XO adult) ES2 (XX progeny). ME0. OA>10: e2102, e2106 etc. (all similar to e2105),b245ts (pka isx-2,  weaker allele causes only partial XO feminization at 25C, XX self-fertile at 20C). Cloned: encodes predicted 449 aa protein, with similarity to protein phosphatase class 2C. [Kimble et al. 1984\; Hodgkin 1986\; Pilgrim et al. 1995\; DP]"	
"fem-3"	"IV"	4.10182	"[C.elegansII] e1996sd,mat,och : XO animals transformed into fertile females if mother homozygous, into intersexes if mother heterozygous\; XX animals fertile females. Some e1996\/+ XX animals female. Some e1996\/+ sons of e1996 mothers are feminized. ES3 (XO adult) ES2 (XX adult). ME0. OA>20 e1950, e2068amb, e2006ts (XX self-fertile at 20C). Also gf,ts alleles, q20sd,ts (at 25C XX germline makes only sperm, at 15C XX germline makes oocytes and excess sperm. ES3 (progeny) ME3. OA8(gf):q22ts (weaker), q95ts (strongest allele, 80\% Mog even at 15C). Cloned: 1.7 kb and 1.55 kb (minor) transcripts, former encodes predicted 388 aa novel protein. gf alleles are alterations in 3'UTR.  Transgene overexpression of fem-3 leads to extensive masculinization of XX soma. [Hodgkin 1986\; Ahringer et al. 1992\; CB\; JK\; AS]"	
"fer-1"	"I"	2.91454	"[C.elegansII] hc1ts : hermaphrodites and males grown at 25C produce nonfunctional nonmotile sperm with short pseudopods\; membranous organelles fail to fuse with sperm plasma membrane\; TSP in L4. Similar phenotype in hcl\/Df. ES2 (adult). Self-fertility < 1\% (25C) 100\% (16C). Sperm normal if grown <25C.OA7: hc80 (nonconditional), hc24 (leaky ts), b232 etc. Cloned: cosmid rescue (C02D7). 7 kb transcript, encodes probable novel protein. [Ward et al. 1981\; BA]"	
"fer-2"	"III"	7.04905	"[C.elegansII] hc2ts : hermaphrodites and males grown at 25C produce nonfunctional nonmotile sperm with aberrant pseudopods, perinuclear tubules. TSP L2-L4. Self fertility 2\% (25C) 70\% (16C). ES2 (adult). NA1. [Ward et al. 1981\; BA]"	
"fer-4"	"V"	2.76438	"[C.elegansII] hc4ts : hermaphrodites and males grown at 25C produce nonfunctional nonmotile sperm with aberrant pseudopods, perinuclear tubules. Skewed transmission ratio from hc4\/+ males, implying haplo-expression. Self-fertility 3\% (25C) 50\% (16C). ES2 (adult). NA1. hc4\/Df hermaphrodites have abnormal gonads with no oocyte production, no rescue by wild-type sperm. [Ward et al. 1981\; BA]"	
"fer-6"	"I"	2.88221	"[C.elegansII] hc6ts : hermaphrodites and males grown at 25C produce few sperm with defective pseudopods and retention of fibrous bodies. Self-fertility 1\% (25C) 50\% (16C). TSP L4. ES2 (adult). NA1. (hc23ts (pak fer-5) is probably reisolate of hc6). [Ward et al. 1981\; BA]"	
"fer-7"	"I"	-1.91792	"[C.elegansII] hc34ts : hermaphrodites and males grown at 25C produce nonfunctional nonmotile sperm. Self-fertility 6\% (25C) 40\% (16C). TSP L4. ES2 (adult). NA1. [Argon and Ward 1980\; BA]"	
"fer-14"	"X"	6.32837	"[C.elegansII] hc14ts : hermaphrodites and males grown at 25C produce nonfunctional motile spermatozoa\;sperm from Fer-14 males can outcompete WT hermaphrodite sperm. Self-fertility < 0.5\% (25C) 8\% (16C). ES2 (adult). NA1. [BA\; DS\; SL]"	
"fer-15"	"II"	0.78789	"[C.elegansII] hc15ts : hermaphrodites and males grown at 25C produce spermatids that fail to activate into spermatozoa. Self-fertility < 1\% (25C) 100\% (16C). ES2 (adult). Similar phenotype in hc15\/Df. OA2: hc89, b26. See also age-1. [Roberts and Ward 1982\; BA\; TJ\; SL]"	
"flp-1"	"IV"	4.12	"[C.elegansII] pk41 : Tc1 insertion,  no known phenotype. Cloned: encodes FMRF-containing neuropeptides.Six exons, four encode FMRFamide-like peptides.Alternatively spliced transcripts. [Rosoff et al. 1992\;  NY]"	
"flr-1"	"X"	12.3182	"[C.elegansII] ut1 : resistant to 400 ug\/ml NaF. Slow growth. Small. OA5: ut2, ut4, ut6, ut11, sa96 (very short defecation cycle period, often with weak or missing motor program steps, Con, scrawny and slow growing, fluoride resistant\; appears to feed normally). Cloned: encodes protein with some similarity to DEG-1\/MEC-4 family. [Katsura et al. 1994\; Iwasaki et al. 1995\; JC\; JT]"	
"flr-2"	"V"	3.49508	"[C.elegansII] ut5 : partially resistant to 400 ug\/ml NaF\; normal defecation. OA1: ut71. [Katsura et al. 1994\; JC\; JT]"	
"flr-3"	"IV"	-29.1373	"[C.elegansII] ut9 : resistant to 400 ug\/ml NaF. Slow growth. Small.  Very short defecation cycle period.OA2: ut8, ut10. Cloned: encodes protein with some similarity to kinases, but lacks ATP-binding consensus. [Katsura et al. 1994\; Iwasaki et al. 1995\; JC\; JT]"	
"flr-4"	"X"	19.9891	"[C.elegansII] ut3 : resistant to 400 ug\/ml NaF. Slow growth. Small.  OA2: ut7, sa201 (ts, at 25C very short defecation cycle period, often with weak or missing motor program steps, Con, scrawny and slow growing, fluoride resistant\; appears to feed normally). Cloned: cosmid rescue (F09B12). [Katsura et al. 1994\; Iwasaki et al. 1995\; JC\; JT]"	
"flr-5"	"V"	1.89925	"[C.elegansII] ut73 : partially resistant to 400 ug\/ml NaF.Normal defecation. [Katsura et al. 1994\; JC\; JT]"	
"flu-2"	"X"	-3.59653	"[C.elegansII] e1003 : reduced gut fluorescence dull green\; high orthoaminophenol content low kynureninase levels enhanced mutagen sensitivity. ES1. ME3. OA4. [Babu 1974\; Bhat and Babu 1980]"	
"fog-1"	"I"	-4.43148	"[C.elegansII] e1959sd : homozygous XX animals transformed into fertile females\; homozygous XO animals are somatically male, make oocytes in germ line\; heterozygous XO animals are somatically male with both sperm and oocytes in germline. ES2 (adults). OA>10: e2121, e1959, e2122, q155, q253ts (fertile at 15C). [Barton and Kimble 1990\; Ellis and Kimble 1995\; JK\; RE]"	
"fog-2"	"V"	24.9622	"[C.elegansII] q71 : XX animals transformed into females XO animals wildtype males. ES3 (adult XX) ME3. OA5. [Schedl and Kimble 1988\; BS]"	
"fog-3"	"I"	4.52622	"[C.elegansII] q469 : XX animals transformed into females, XO animals somatically male, make oocytes in germ line.  q469\/Df similar.  No dominant phenotypes. ES3 (adult XX), ME0.OA>10: q441, q443, q470, q520fdi, q502uvp,oz137, oz147. [Ellis and Kimble 1995\; RE]"	
"fox-1"	"X"	-14.3934	"[C.elegansII] Extra copies of locus lead to dominant XO lethality and feminization. Cloned: 1.8 kb transcript, encodes predicted  415 aa protein with RNP motif. [Hodgkin et al. 1994\; CB\; TY]"	
"ges-1"	"V"	-18.9358	"[C.elegansII] cal : electrophoretic variant of major gut esterase. No other phenotype. ES1 ME3. OA>10: ca4, ca6 etc (all electrophoretic variants), ca6ca7, ca6ca9, ca10, ca11 etc (null mutations, major gut esterase activity absent, no other phenotype) pk47, pk49 (Tc1 insertions\; deletionderivatives also obtained). Cloned: encodes gut-specific esterase,expressed from 200-cell stage onward. Extensive promoter analysis. [McGhee et al. 1990, Aamodt et al. 1991, JM]"	
"gld-1"	"I"	2.24	"[C.elegansII] q485 : hermaphrodite germ cells enter meiosis, fail in pachytene, re-enter mitosis and form large proximal germline tumor\; males unaffected. Probable null phenotype.  ES3 (adult), ME3.OA>15: multiple phenotypic classes and subclasses, class A: q268, q365 (probable nulls, resemble q485)\; class B: q93oz12 (sperm, then germ cells arrested in pachytene)\;class C: q93 (gf, Mog)\; class D: q126 (gf, Fog)\; class E: q266 (gf, Fog, abnormal oocytes)\; class F: q343 (sperm, then abnormal oocytes).  Complex complementation. Cloned: encodes predicted 463 or 466 aa proteins,with similarity to shrimp GRP33, mouse Src-associated protein Sam68\; includes KH (possible RNA binding) domain. [Francis et al. 1995 \; Jones and Schedl 1995\; BS]"	
"gld-2"	"I"	1	"[C.elegansII] h292 : sterile adult.  NA1[KR]"	
"gld-2"	"I"	1	"[C.elegansII] q497 : germ cells enter meiosis, fail in pachytene, make enlarged oocyte-like cells.  Spermatogenesis also defective in males.  In presence of extragenic modifier (q525), proximal germ line becomes mitotic.  NA1. [JK]"	
"glp-1"	"III"	0.145748	"[C.elegansII] q46 : germ cells divide only a few times in both XX and XO forming 10-20 sperm\; somatic gonad superficially wildtype. Mosaic analysis indicates germline focus. ES3 (adult). OA>10: q35, q50 (both have weaker phenotype than q46, some oocyte production, fertilized eggs arrest during embryogenesis)\;e2072 (Mel, late embryonic arrest, no AB derived pharyngeal cells, variable hypodermal defects),e2141ts, e2144ts (both Mel at 25C),  g60ts,mm (pka emb-33, at 25C 100\% eggs arrest at lima bean or earlier, misplaced gut granule birefringence. Escapers have abnormal gonadogenesis. L1 temperature shift-up results in viable adult F1 Emb. At 16C viable).Also gf alleles, q35sd (causes Muv, extra vulval differentiation, mimics lin-12(gf))\; oz112gf (dominant germ line tumorous inboth sexes, some Muv, extra vulval differentiation).See also sog, ego, lag, lin-12 etc.\; lag functions redundant with lin-12. Cloned: 4.4 kb transcripts, encodes 1295 aatransmembrane receptor, closely related to LIN-12, Drosophila Notch, etc.\; extracellular 10 EGF-like repeats, other repeats\; intracellular 6 ANK repeats, etc.  Antibody staining indicates GLP-1 membrane-associated in early embryo, AB descendants, mitotic germ cells, not detected in gametes.Very extensive developmental and molecular analysis. [Austen and Kimble 1987, 1989\; Priess et al. 1987\; Yochem and Greenwald 1989\; Crittenden et al. 1994\;   JK\; BS\; GE\; JR\; GS]"	
"glp-3"	"III"	-0.88	"[C.elegansII] q145 : sterile, no germ line proliferation in hermaphrodites or males\; about 3 undifferentiated germ cells per gonad arm.  No somatic defects.  OA4: q156, q171, q363, q456 (all similar). [JK]"	
"glp-4"	"I"	20.8135	"[C.elegansII] bn2ts : hermaphrodites raised at 25C sterile,~12 germ line nuclei, non-reflexed gonad arms\; males at 25C ~16 germ line nuclei, normal soma. Germ cells arrested at meiotic prophase. Fertile at 16C\; TSP throughout larval development.OA3: om14 (proliferation normal\; oocytes small,irregular\; other germline abnormalities), om23 (weaker phenotypes), om24. Also probable intragenic revertants of bn2:bn2bn39, bn2bn40 (some fertility at 25C). [Beanan and Strome 1992\; Qiao et al. 1995\; EL\; SS]"	
"goa-1"	"I"	2.05089	"[C.elegansII] sy192 : hyperactive, Egl-c, defective male mating OA3: pk39 (Tc1 insertion, similar phenotypes),n363, n1134 (some axon guidance defects ?) Cloned: encodes homolog of mammalian G protein alpha subunit (>80\% identity).  goa-1:lacZ expressed in most neurons,some muscle cells, pharynx, distal tip cells.  Transgene overexpression leads to lethargy,slow pumping, egg-laying defects, irregular defecation. [Mendel et al. 1995\; Segalat et al. 1995\; KP\; PS]"	
"gon-1"	"IV"	4.35	"[C.elegansII] e1254 : defective formation of somatic gonad primordium\; much germ line proliferation, almost no gamete maturation, variable vulval induction, no uterus.  e1254\/Df similar.ES3. ME0 (male somatic gonad also abnormal).  OA4:e2547, e2551, q517, q518 (similar). [Hodgkin et al. 1989\; CB\; JK]"	
"gon-2"	"I"	2.88	"[C.elegansII] q362 :partial maternal effect gonadless (Z1 and Z4 often fail to divide).  OA3: q388ts (zygotic sterile at 25C, fertile 15C, upshift gives Gon progeny), dx12, dx13. Cloned : cosmid rescue (T01H8)[EJ]"	
"gon-4"	"IV"	4.54319	"[C.elegansII] e2575 : abnormal gonad development,sterile\; vulva development mostly abnormal, some spermatogenesis, little oogenesis. Often failure of division of Z1, Z4.OA2: q519, q521. [CB\; JK]"	
"gon-10"	"V"	6.36488	"[C.elegansII] e1795 : hermaphrodites have very abnormal swollen proximal gonad with apparent giant oocytes, additional non-gonadal somatic abnormalities, sterile, variable tail malformationNA1. [CB]"	
"gpb-1"	"II"	3.99	"[C.elegansII] pk13.  Tc1 insertion, also excision derivatives pk44: recessive lethal, arrests at L1 stage with very little body wall or pharyngeal muscle activity.  In absence of maternal rescue, probably arrests as early embryonic lethal. [NL\; JA]"	
"gro-1"	"III"	-1.99372	"[C.elegansII] e2400spo,mat : postembryonic growth rate greatly reduced, increased resistance to heat-shock, some increase in life-span\; tends to avoid bacterial lawn, Complete maternal rescue. ES0 (zygotic), ES2. ME2. Polymorphic in wild isolate (Palm Canyon, CA). NA1. [CB\; DR]"	
"gro-2"	"IV"	9.49581	"[C.elegansII] e2442spo,mat : postembryonic growth rate greatly reduced, tends to avoid bacterial lawn.  Spontaneous mutation from cross with Bergerac strain. Complete maternal rescue.  ES0 (zygotic), ES2.  ME2. NA1. [CB\; MQ]"	
"gro-3"	"I"	18.6829	"[C.elegansII] e2556spo,mat : no obvious zygotic phenotype\; in absence of maternal rescue, homozygotes are very slow-growing, slow-moving, Egl, tend to avoid bacterial lawn. ES0(zygotic), ES2. ME1.  e2556 spontaneous in N2 background. NA1. [CB]"	
"gus-1"	"I"	25.8715	"[C.elegansII] b405 : beta-glucuronidase activity reduced > 99\%. No gross phenotype. ES1. NA11: b410 (slight activity), gb25 etc.Also intragenic revertants e.g. gb94b410. Probable structural gene. [Sebastiano et al. 1986\; NA]"	
"ham-1"	"IV"	5.92894	"[C.elegansII] n1438 : multiple HSN defects, Egl, Dyf\; HSN and sister phasmid neuron PHB both abnormal\; also disrupted asymmetry in other sister cells RID, ADE\/ADA, ADL, ALN\/PLM.  OA1: n1810. Cloned: 1.8 kb RNA, encodes 414 aa novel protein. [Desai et al. 1988\; Garriga and Stern 1994\; NG\; NH\; MT]"	
"hch-1"	"X"	17.9445	"[C.elegansII] e1734 : delayed hatching from eggshell rescued by protease or wildtype hatching fluid\; QL and descendant cells migrate forward instead of backward. ES1. OA1: e1907 (same phenotypes). [Hedgecock et al. 1987\; NJ]"	
"her-1"	"V"	2.11081	"[C.elegansII] e1518 : XX animals WT,  XO animals transformed into fertile hermaphrodites. ES3 (XO). Similar phenotype in e1518\/Df. OA>20: e1520, e1561ts (XO fertile male 15C, fertile hermaphrodite25C), q428ts (very weak Her), etc. Also gain-of-function alleles: n695sd,ts(XO animals WT, XX animals partly masculinized Egl  hermaphrodites\; n695\/+ XX animals slightly masculinized),y101 (stronger masculinization, still incomplete).  Intragenic revertants are recessive Her-1 alleles:n695n826, y1hv101 (viable deletion), etc.  ES2 (XX). NA1. Intragenic revertants have Class 1 phenotype. Cloned: 0.8 and 1.2 kb transcripts, XO specific\;1.2 kb transcript necessary and sufficient, encodes175 aa predicted cysteine-rich novel protein with signal sequence. [Hodgkin 1980\; Perry et al. 1993, 1994\; NT\; PA]"	
"him-1"	"I"	-0.244898	"[C.elegansII] e879sd : self-progeny 21\% XO male, 5\% 3X herm\; 8\% ova are nullo-X as a result of reductional meiotic nondisjunction\; X chromosome recombination specifically reduced 40\% or more, except at left end (recombination increased)\; Rad.e879\/+ self-progeny 1\% XO. ES3 (progeny). ME2. NA1. [Hodgkin et al. 1979\; Broverman and Meneely 1994]"	
"him-2"	"I"	6.98182	"[C.elegansII] e1065 : self progeny 2\% XO male\; 1.5\% ova are nullo-X\; some associated sterility.ES2 (progeny). ME3. NA1. [Hodgkin et al. 1979]"	
"him-3"	"IV"	1.9679	"[C.elegansII] e1147 : self-progeny 3.5\% XO male 2\% ova are nullo-X. ES2 (progeny). ME3. OA1: e1256 (stronger allele,  11\% Him many unhatched eggs (71\%)\; males sire inviable zygotes\; probably generalized meiotic nondisjunction\; some reduction in autosomal recombination, effects on segregation of free duplications). [Hodgkin et al. 1979\; KR]"	
"him-4"	"X"	1.13008	"[C.elegansII] e1267icr : self-progeny 6\% XO male, very low brood size\; frequent gonad eversion with rupture at vulva\; 2\% nullo-X ova. Male gonad abnormal, testis fails to connect with proctodeum, may be twice reflexed. Mua (muscle attachment) phenotype, general defects in transhypodermal anchorage. ES2 (adult). ME0. OA2: e1266icr (same phenotypes), rh166. [Hodgkin et al. 1979\; NJ]"	
"him-5"	"V"	5.85747	"[C.elegansII] e1467ts : at 20C self-progeny 16\% XO male, 3\% 3X herm, 11\% ova are nullo-X as a result of reductional meiotic nondisjunction\; X chromosome recombination specifically reduced 50\% or more, except at left end (increased)\; additional sterility not due to autosomal nondisjunction ( brood reduced 64\% at 25C)\; some embryonic lethality. ES3 (progeny). ME3. OA4: e1490 (stronger allele : 33\% Him at 20C)). Cloned: cosmid rescue K02A12. [Hodgkin et al. 1979\; Broverman and Meneely 1994\; FH]"	
"him-6"	"IV"	6.26879	"[C.elegansII] e1423 : self-progeny 15\% XO male, 6\% 3X herm,low brood size (78\% unhatched eggs) 8\% nullo-X ova as a result of reductional meiotic nondisjunction\; autosomal nondisjunction\; males sire inviable zygotes. ES3 (progeny). ME3. OA1: e1104 (weaker allele : 5\% Him). [Hodgkin et al. 1979, Haack and Hodgkin 1991\; KR]"	
"him-7"	"V"	-5.1265	"[C.elegansII] e1480 : self-progeny 3\% XO male, 0.6\% nullo-X ova\; males make slight excess of nullo-X sperm, sire some inviable zygotes. ES2 (progeny). ME3. NA1. [Hodgkin et al. 1979]"	
"him-8"	"IV"	4.69379	"[C.elegansII] e1489 : self-progeny 37\% XO male, 6\% 3X herm,38\% nullo-X ova as a result of reductional meiotic nondisjunction X chromosome recombination specifically reduced 90\% except at left end (increased) ES3 (progeny). ME2. OA6: mn253, ec51 etc.(all  >30\% Him)). Cloned: cosmid rescue T19G9 [Hodgkin et al. 1979\; Broverman and Meneely 1994\;  SP\; FH]"	
"him-9"	"II"	4.84324	"[C.elegansII] e1487aci : self-progeny 5\% males, 2\% nullo-X ova. ES3 (progeny). ME3. NA1. [Hodgkin et al. 1979]"	
"him-10"	"III"	-1.72475	"[C.elegansII] e1511ts : self-progeny 2\% XO male (15C) 12\% male (20C) 27\% male (25C) low brood size many unhatched eggs at 25C.Probably some chromosome loss in premeiotic germ-line: abnormal mitotic cytology, jackpots in male production. ES3 (progeny 25C). ME3 (20C). NA1. [Hartman and Herman 1982\; AV]"	
"him-14"	"II"	0.571537	"[C.elegansII] it44ts : viable self-progeny 2--40\% male,95\% dead eggs, probable generalized nondisjunction,meiotic defect.  OA4: it13, it21, it23, it52 (strongest allele, <3\% eggs hatch). [Kemphues et al. 1988]"	
"hlh-1"	"II"	-4.50501	"[C.elegansII] cc450am : recessive lethal, arrest at varying stages as lumpy dumpy with some muscle differentiation, disorganized myofilaments. Encodes member of MyoD family.  Transcripts present transiently in MS descendants, stably in D daughters and C and MS lineages leading to body wall muscle. Antibody staining similar (nuclear staining, persists through development of body wall muscle cells). [Krause et al. 1990, 1994\; Chen et al. 1992\; KM\; PD]"	
"hsp-1"	"IV"	17.5005	"[C.elegansII] NMK.  Encodes protein related to generic hsp70.  Quite strong expression normally, only weak heat shock induction. [Heschl and Baillie 1990\; BC]"	
"kin-15"	"II"	1.34	"[C.elegansII] Tc1 insertion : retarded development?  Encodes predicted tyrosine kinase with transmembrane domain, no large extracellular domain.  Related to kin-16. [Morgan and Greenwald 1993\; WR]"	
"ksr-1"	"X"	-0.579116	"[C.elegansII] pka sur-3, sar-2.  Mutations suppress ras mutation,let-60(n1046gf).  No phenotype alone in VPC\; some larval lethality, Egl and Mig phenotypes. [MT\; MH]"	
"lag-1"	"IV"	2.95015	"[C.elegansII] q385 : larval arrest at L1, characteristic Lag (Lin-12 and Glp-1) phenotype: rectum\/anus and excretory cell absent (98\%), sometimes twisted nose (12\%). OA>10 (other alleles mostly weaker): q416 (sometimes viable and fertile at 20C), q426 (low larval lethality), om13 (viable, impenetrant embryonic and larval lethality\; strong Ego, enhances glp-1(bn18ts)), om27(viable, Ego), om108 (viable, Ego), etc. Cloned: 2.6 kb transcript, encodes protein with high similarity to Drosophila Suppressor of hairless. [Lambie and Kimble 1991\; JK]"	
"lag-2"	"V"	-10.3226	"[C.elegansII] q387 : larval arrest at L1, characteristic Lag (Lin-12 and Glp-1) phenotype: rectum\/anus absent, excretory cell absent, often twisted nose (76\%). Similar phenotype in q387\/Df. NA >6: q420 (weaker allele), s1486 (pka let-461), ut103 and ut105 (both Clr).  Also gf alleles: n1255, sa37 (pka sel-3,partly suppresses lin-12(gf) mutations.) Cloned: encodes 400 aa membrane protein with similarity to Drosophila Delta and Serrate\;transcript present in DTC. [Johnsen and Baillie 1991\; Tax et al. 1994\; Henderson et al. 1994\; MT\; JC]"	
"lep-1"	"I"	3.9259	"[C.elegansII] bx37sd : male tail tip is pointy and protrudes beyond the posterior edge of the fan, 100\%penetrant. No hermaphrodite phenotype. OA1: bx42sd (92\% penetrant). [DF]"	
"let-1"	"X"	19.8222	"[C.elegansII] mn119 : early larval lethal. OA5: mn124, mn102 (late larval lethal), mn115 (hermaphrodite sterile, lays fertilized eggs, male sterile) etc. [Meneely and Herman 1981\; SP]"	
"let-2"	"X"	23.7694	"[C.elegansII] mn153amb : embryonic lethal. OA>15:(many ts, complex interallelic complementation pattern),  mn114ts (pka let-8), b246ts, e1470ts, g30ts (inviable 20C),b246ts (viable 20C), q37ts (Mig, Q daughters affected), st550 (embryonic lethal, late paralysis,elongation arrest at 2-fold) etc. High forward mutation frequency. See also sup-20. Cloned: encodes 1795 aa Type IV (basement membrane) collagen, alpha2 chain (pka clb-1)\; alternative splicing [Kramer] either exon 9 (higher in embryo) or exon 10 (higher in larva, adult). [Meneely and Herman 1981\; Sibley et al. 1993\; CF\; CH\; MT\; RW\; SP]"	
"let-2"	"X"	23.7694	"[C.elegansII] n821 : recessive suppressor of unc-105(n490).Mosaic analysis indicates focus in muscle cells.OA2 (viable suppressor alleles): n1168, n1169.Also many recessive lethal alleles (embryonic arrest), probable nulls.  Suppressor alleles fail to complement let-2, probably allelic. [Park and Horvitz 1986b\; MT]"	
"let-3"	"X"	22.4655	"[C.elegansII] mn104amb : early larval lethal, incompletely suppressible by sup-5. NA1. [Meneely and Herman 1981\; SP]"	
"let-4"	"X"	17.4367	"[C.elegansII] mn105amb : early larval lethal\; cystic excretory canals. NA1. [Meneely and Herman 1981\; NJ\; SP]"	
"let-5"	"X"	17.5419	"[C.elegansII] mn106amb,mat,mnz : progeny grow slowly, fail to reach adulthood. OA1: mn132 (similar). [Meneely and Herman 1981\; SP]"	
"let-6"	"X"	24.1367	"[C.elegansII] mn130 : early larval lethal. OA3: mn108 etc. [Meneely and Herman 1981\; SP]"	
"let-7"	"X"	18.6544	"[C.elegansII] mn112 : late larval lethal, XX animals die at early L3\; XO die at late L4. OA1: mn107 (sterile). [Meneely and Herman 1981\; SP]"	
"let-9"	"X"	17.6396	"[C.elegansII] mn107 : sterile\; defective sperm. NA1. [Meneely and Herman 1981\; SP]"	
"let-10"	"X"	22.4569	"[C.elegansII] mn113 : early larval lethal. OA1: mn118. [Meneely and Herman 1981\; SP]"	
"let-11"	"X"	22.4109	"[C.elegansII] mn116 : early larval lethal. NA1. [Meneely and Herman 1981\; SP]"	
"let-12"	"X"	20.6549	"[C.elegansII] mn121amb : early larval lethal. OA1: mn125(pka let-17, similar). [Meneely and Herman 1981\; SP]"	
"let-14"	"X"	22.4857	"[C.elegansII] mn120 : early larval lethal. NA1. [Meneely and Herman 1981\; SP]"	
"let-15"	"X"	21.8261	"[C.elegansII] mn127amb : early larval lethal. OA2: mn123, e1471. [Meneely and Herman 1981\; SP]"	
"let-16"	"X"	23.4871	"[C.elegansII] mn117 : early larval lethal. NA1. [Meneely and Herman 1981\; SP]"	
"let-18"	"X"	21.8261	"[C.elegansII] mn122amb : embryonic lethal, incompletely suppressible by sup-5. OA2: mn142, mn136 (late larval lethal). [Meneely and Herman 1981\; SP]"	
"let-19"	"II"	0.819153	"[C.elegansII] mn19 : larval lethal. NA1. [Sigurdson et al.\; SP]"	
"let-21"	"II"	3.67528	"[C.elegansII] e1778 : sterile uncoordinated polynucleate oocytes, abnormal positioning of germ linenuclei. NA1. [NJ]"	
"let-22"	"II"	-0.264625	"[C.elegansII] mn22 : embryonic lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-23"	"II"	1.03811	"[C.elegansII] mn23 : early larval lethal. OA>15: sy15(rod-like early larval lethal, probable null), sy5 (similar tosy15, W1078op), mn224 (earlylarval lethal, non-null), n1045 (homozygousviable, Vul at 15C, weak Muv (hyperinduced) at25C\; P12 transformed to P11 fate), sy1 (viable, Vul, Q1318och), sy97 (viable,Vul, ME0, abnormal spicules), sy10 (impenetrant larval lethal, survivors sterile, Emo, abnormal oocytes), etc.Alleles affect subset or all of 5 phenotypes (L1 viability, vulval induction, male spicules,oogenesis, P12).  Also gf allele sa62sd (scrawny Muv, sa62\/+ variable Muv, 5-50\%) Cloned: 4.9 kb transcript, encodes 1323 aa EGF-receptor class tyrosine kinase (pka kin-7)\;let23:lacZ expressed in many but not all cells.Extensive molecular and developmental analysis.See also lfe, sli, etc. [Sigurdson et al. 1984\; Aroian et al. 1990\; Aroian and Sternberg 1991\; Aroian et al. 1994\; Koga and Ohshima 1995\; FK\; SP]"	
"let-24"	"II"	0.694894	"[C.elegansII] mn24 : early larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-25"	"II"	2.6986	"[C.elegansII] mn25 : early larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-26"	"II"	4.25626	"[C.elegansII] mn26 : early larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-30"	"II"	-1.11546	"[C.elegansII] mn30 : embryonic  lethal. OA1: mn239. [Sigurdson et al. 1984\; SP]"	
"let-31"	"II"	1.46251	"[C.elegansII] mn31 : embryonic lethal. OA1: mn223. [Meneely and Herman 1981\; SP]"	
"let-33"	"X"	22.9799	"[C.elegansII] mn128mat,mm : Mel, homozygotes lay fertilized eggs that do not hatch, no male rescue but males fertile\; mn128\/Df is sterile. NA1. [Meneely and Herman 1981\; SP]"	
"let-34"	"X"	20.53	"[C.elegansII] mn134 : early larval lethal. NA1. [Meneely and Herman 1981\; SP]"	
"let-35"	"X"	22.4391	"[C.elegansII] mn135 : early larval lethal. NA1. [Meneely and Herman 1981\; SP]"	
"let-36"	"X"	21.2401	"[C.elegansII] mn140 : slow growth, late larval lethal or adult producing inviable progeny\; rescued by mating\; mn140\/Df is early larval lethal. NA1. [Meneely and Herman 1981\; SP]"	
"let-37"	"X"	22.9799	"[C.elegansII] mn138 : early larval lethal. NA1. [Meneely and Herman 1981\; SP]"	
"let-38"	"X"	21.8261	"[C.elegansII] mn141mat mnz : Mel, homozygotes lay fertilized eggs that do not hatch, males fertile\; mn141\/Df is sterile. NA1. [Meneely and Herman 1981\; SP]"	
"let-39"	"X"	21.2401	"[C.elegansII] mn144amb : early larval lethal, incompletely suppressible by sup-5. NA1. [Meneely and Herman 1981\; SP]"	
"let-40"	"X"	21.8261	"[C.elegansII] mn150ts : early larval lethal at 25C, dumpyish sterile with abnormal gonads at 20C\; males fertile\; mn150\/Df is early larval lethal at 20C. NA1. [Meneely and Herman 1981\; SP]"	
"let-41"	"X"	22.9799	"[C.elegansII] mn146amb : early larval lethal incompletely suppressible by sup-5. NA1. [Meneely and Herman 1981\; SP]"	
"let-42"	"III"	1.54707	"[C.elegansII] g38 : leaky maternal effect lethal phenotype at 25C. Animals which develop to adulthood are sterile, frequently Evl. OA1: oz36 (similar phenotype at 25C, also impenetrant late-onset tumorous germline phenotype,strongest at 15C.  oz36 males exhibit some tumorous germ lines, some oogenesis and yolk synthesis). [RC\; BS]"	
"let-43"	"X"	-8.58789	"[C.elegansII] mg49 : larval lethal [GR\; DG]"	
"let-44"	"X"	-7.95753	"[C.elegansII] mg41 : embryonic lethal [GR\; DG]"	
"let-45"	"I"	13.6	"[C.elegansII] h1292: lethal.  NA1. [KR]"	
"let-46"	"I"	13.6	"[C.elegansII] h1297 : lethal.  OA3: h1330, h1337, h1359. [KR]"	
"let-47"	"I"	13.6	"[C.elegansII] h1319 : lethal. NA1. [KR]"	
"let-48"	"I"	13.6	"[C.elegansII] h1320 : lethal. NA1. [KR]"	
"let-49"	"I"	27.1874	"[C.elegansII] st44 : mid-larval lethal. NA1. [Anderson and Brenner 1984\; RW]"	
"let-50"	"I"	27.474	"[C.elegansII] st33 : early larval lethal. NA1. [Anderson and Brenner 1984\; RW]"	
"let-51"	"IV"	4.62945	"[C.elegansII] s41 : embryonic lethal, cystic excretory canals. NA1. [Rogalski et al. 1982\; BC\; NJ]"	
"let-52"	"IV"	5.52532	"[C.elegansII] s42 : early larval lethal. OA2: s2346 (homozygote and hemizygote arrest at L2),  s2381 (L3 arrest, s2381\/Df L2 arrest). Cloned: cosmid rescue (T12G3). [Clark et al. 1988\; BC]"	
"let-53"	"IV"	4.56046	"[C.elegansII] s43 : late larval lethal. NA1. [Rogalski et al. 1982\; BC]"	
"let-54"	"IV"	4.05979	"[C.elegansII] s44 : early larval lethal (L1-L2 molt). OA1: s53 (similar). [Rogalski et al. 1982\; BC]"	
"let-55"	"IV"	4.61358	"[C.elegansII] s45 : early larval lethal. NA1. [Rogalski et al. 1982\; BC]"	
"let-56"	"IV"	5.42383	"[C.elegansII] s173 : slow development, eventually reaches sterile adult stage after 7 days\; s173\/Df slower development initially, still reaches sterile adult stage.OA>10: s46 (late larval lethal, hemizygote mid-larval lethal)\; s50, s168 (late larval lethals)\;s1210, s1223, s1262 (homozygotes and hemizygotes mid larval lethal)\; s173 (homozygote and hemizygote arrest as sterile adults)\; s2217, s2230, s2321(resemble s173). Cloned: cosmid rescue, C11F2. [Clark et al. 1988\; Clark and Baillie 1992\; BC]"	
"let-59"	"IV"	4.88587	"[C.elegansII] s49 : early larval lethal\; hemizygote embryonic\/early larval lethal. OA5: s175 (pka let-62,  embryonic lethal), s681, s1087, s1174, s1197. [Rogalski and Baillie 1985\; Clark et al. 1988\; BC]"	
"let-60"	"IV"	5.17841	"[C.elegansII] s59 : mid-larval lethal (leaky, escapers non-Vul). OA>10 (recessive): s1124 (strongest allele, both homozygote and hemizygote arrest as rod-like early larva\; rare escapers die as Vul adult), s2336 (homozygote L3 arrest, hemizygote L2 arrest), s1155, n2021 (viable, 14\% Vul), etc. Weak lf mutations have mating defects.Also dominant negative alleles, OA8: sy93dm (dominant Vul, viable), sy99 (dominant Vul,recessive lethal), sy92 (weaker dominant, recessive lethal), etc.Also gf alleles, OA>5: n1046sd,amb (pka  lin-34, non-null\; adult hermaphrodite Muv(penetrance 57\%), normal vulva with one to three large additional protrusions\; n1046\/+17\% Muv. ES2.  Male gross morphology wildtype, ME1),n1700, sy130 (all identical to n1046), ga89ts(at 25C 57\% Muv, near-sterile, ME0). Cloned: encodes 143 aa ras protein.  let-60:lacZ fusion indicates complex developmental expression, multiple functions.  Extensive molecular and developmental analysis. [Rogalski et al. 1982\; Han and Sternberg 1990, 1991\;Beitel et al. 1990\; BC\; MH\; MT\; PS\; SD]"	
"let-61"	"IV"	4.63072	"[C.elegansII] s65 : late larval lethal. s65\/Df similar. NA1. [Clark et al. 1988\; BC]"	
"let-63"	"IV"	4.69338	"[C.elegansII] s170 : mid-larval lethal\; s170\/Df similar. OA2: s679 (late larval lethal), s1766. [Clark et al. 1988\; BC]"	
"let-64"	"IV"	4.84078	"[C.elegansII] s216 : thin sterile adult progeny\; not rescued by wildtype sperm. OA3: s171 (leaky sterile adult), s697 (pka let-74, late larval lethal,s697\/Df similar), s1746. [Clark et al. 1988\; BC]"	
"let-65"	"IV"	5.12187	"[C.elegansII] s254 : nonconditional constitutive formation of abnormal dauer-like larvae, arrested.NA11: s174, s694, s1084, s1154, s1222, s1730, s1777 (all resemble s254), s694 (sterile adult0,s1083  (homozygote is mid-larval lethal, hemizygote is sterile adult). [Clark et al. 1988\; BC\; DR]"	
"let-66"	"IV"	5.70547	"[C.elegansII] s176 : early larval lethal, s176\/Df mid larval lethal. OA1: s1739 (homozygote and hemizygote both early larval lethal). [Clark et al. 1988\; BC]"	
"let-67"	"IV"	5.70555	"[C.elegansII] s214 : sterile adult, rescued by wild type sperm\; s214\/Df is mid larval lethal. NA1. [Clark et al. 1988\; BC]"	
"let-68"	"IV"	5.76685	"[C.elegansII] s1258 : early larval lethal, s1258\/Df similar.OA4: s1081 (early larval lethal), s693, s696, s698 (some alleles arrest at sterile adult stage). [Clark et al. 1988\; BC]"	
"let-69"	"IV"	4.63072	"[C.elegansII] s684 : late larval lethal. OA3: s1111, s172 (both early larval lethal, s1111\/Df embryonic or early larval lethal). [Clark et al. 1988\; BC]"	
"let-70"	"IV"	4.84633	"[C.elegansII] NMK.  Encodes ubiquitin conjugating enzyme, 134 aa.95\% identical to Drosophila DUC1, 85\% identical to yeast UBC4\/5 (can complement yeast mutant). ubc-2:lacZ strong in larval nervous system, weaker in adult.Corresponds to let-70. [Zhen et al. 1993\; PC]"	
"let-70"	"IV"	4.84633	"[C.elegansII] s689 : mid-larval lethal. OA1: s1132 (early larval lethal, s1132\/Df mid larval lethal). Cloned: corresponds to ubc-2. [Clark et al. 1988\; BC]"	
"let-71"	"IV"	4.75	"[C.elegansII] s692 : leaky sterile adult, s692\/Df is similar. NA1. [Clark et al. 1988\; BC]"	
"let-72"	"IV"	4.69338	"[C.elegansII] s52 : late larval lethal. OA1: s695 (midlarval lethal, s695\/Df similar). [Clark et al. 1988\; BC]"	
"let-73"	"IV"	4.84633	"[C.elegansII] s685 : sterile adult, s685\/Df is similar. OA1: s1747 (sterile adult, hemizygote similar). [Clark et al. 1988\; Clark and Baillie 1992\; BC]"	
"let-75"	"I"	1.86238	"[C.elegansII] s101 : early larval lethal (L1). No pumping, pharyngeal birefringence abnormal\; possibly = myo-1.   OA3: s107, s108, s143. [McKim et al 1992\; Avery 1993\; DA\; KR\;  RW]"	
"let-80"	"I"	2.62976	"[C.elegansII] s96 : L1 lethal. NA1. [Rose and Baillie 1980\; KR]"	
"let-81"	"I"	2.24063	"[C.elegansII] s88 : L1 lethal. NA1. [Rose and Baillie 1980\; KR]"	
"let-82"	"I"	2.24063	"[C.elegansII] s85 : L1 lethal (larva abnormal?). NA1. [Rose and Baillie 1980\; KR]"	
"let-84"	"I"	2.69769	"[C.elegansII] s91 : late larval lethal. NA1. [Rose and Baillie 1980\; KR]"	
"let-85"	"I"	2.24063	"[C.elegansII] s142 : L1 lethal. NA1. [McKim et al. 1992\; KR]"	
"let-86"	"I"	1.4	"[C.elegansII] s141 : L1 lethal. NA1. [McKim et al. 1992\; KR]"	
"let-87"	"I"	2.17544	"[C.elegansII] s106 : semi-viable, L1 lethal with dpy-14(e188). OA2: s87 (L1 lethal), s139. [McKim et al. 1992\; KR]"	
"let-88"	"I"	2.24063	"[C.elegansII] s132 : L1 lethal. NA1. [McKim et al. 1992\; KR]"	
"let-89"	"I"	2.62976	"[C.elegansII] s133 : L1 lethal. NA1. [McKim et al. 1992\; KR]"	
"let-90"	"I"	2.24063	"[C.elegansII] s140 : L1 lethal (larva abnormal?). NA1. [McKim et al. 1992\; KR]"	
"let-91"	"IV"	4.99882	"[C.elegansII] s678 : pka let-95 mid-larval lethal, s678\/Df similar. OA2: s753, s1720.  Anomalous complementation:let-91 (s753)\/let-651(s1185) is lethal, other combinations viable. [Clark et al. 1988\; Clark and Baillie 1992\; BC]"	
"let-92"	"IV"	5.33076	"[C.elegansII] s504 : early larval lethal, s504\/Df similar. OA3: s677, s2021 (homozygote and hemizygote arrest as L2), s2209 (similar). Cloned: partial cosmid rescue B0033. [Clark et al. 1988\; BC]"	
"let-93"	"IV"	5.70369	"[C.elegansII] s734 : mid-larval lethal.  OA2: s2254 (homozygote arrests at L2, hemizygote at L1),s2357 (similar). [Clark et al. 1988\; BC]"	
"let-96"	"IV"	4.63072	"[C.elegansII] s1112 : mid larval lethal, s1112\/Df similar.  OA1: s1732 (late larval lethal). [Clark et al. 1988\; Clark and Baillie 1992\; BC]"	
"let-97"	"IV"	6.12441	"[C.elegansII] s1121 : early larval lethal, s1121\/Df similar.  NA1. [Clark et al. 1988\; Charest et al. 1990\; BC]"	
"let-98"	"IV"	4.84633	"[C.elegansII] s1117 : late larval lethal, s1117\/Df similar. NA1. [Clark et al. 1988\; BC]"	
"let-99"	"IV"	5.93592	"[C.elegansII] s1201 : Mel, s1201\/Df similar. Incorrect spindle orientation in AB and P1.  OA1. Cloned. [Clark et al. 1988\; Charest et al. 1990\; BC\; KK]"	
"let-100"	"IV"	4.84633	"[C.elegansII] s1160 : early larval lethal, s1160\/Df embryonic or early larval lethal.  NA1. [Clark et al. 1988\; BC]"	
"let-201"	"I"	23.5421	"[C.elegansII] e1716 : lethal. NA1. [Anderson and Brenner 1984]"	
"let-202"	"I"	22.9254	"[C.elegansII] e1720 : lethal. NA1. [Anderson and Brenner 1984]"	
"let-203"	"I"	23.5421	"[C.elegansII] e1717 : lethal. NA1. [Anderson and Brenner 1984]"	
"let-204"	"I"	23.5618	"[C.elegansII] e1719 : lethal. NA1. [Anderson and Brenner 1984]"	
"let-205"	"I"	25.4271	"[C.elegansII] e1722 : lethal. NA1. [Anderson and Brenner 1984]"	
"let-206"	"I"	25.4732	"[C.elegansII] e1721 : lethal. NA1. [Anderson and Brenner 1984]"	
"let-207"	"I"	25.662	"[C.elegansII] e1723 : lethal. NA1. [Anderson and Brenner 1984]"	
"let-208"	"I"	29.0305	"[C.elegansII] e1718 : lethal. NA1. [Anderson and Brenner 1984]"	
"let-236"	"II"	0.239341	"[C.elegansII] mn88 : larval lethal. NA1. Possible U1 snRNP 70 kD protein ?[Sigurdson et al. 1984\; SP]"	
"let-237"	"II"	0.789911	"[C.elegansII] mn208 : larval lethal. OA1: b283(Mel, leaky). [Sigurdson et al. 1984\; Kemphues et al. 1988]"	
"let-238"	"II"	0.806347	"[C.elegansII] mn229 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-239"	"II"	0.837839	"[C.elegansII] mn217 : embryonic lethal. OA1: mn93 (similar). [Sigurdson et al. 1984\; SP]"	
"let-240"	"II"	1.2448	"[C.elegansII] mn209 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-241"	"II"	1.59882	"[C.elegansII] mn228 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-242"	"II"	1.83514	"[C.elegansII] mn90 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-243"	"II"	1.97431	"[C.elegansII] mn226 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-244"	"II"	1.97431	"[C.elegansII] mn97 : embryonic lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-245"	"II"	2.40511	"[C.elegansII] mn185 : embryonic lethal. OA1: mn221. [Sigurdson et al. 1984\; SP]"	
"let-246"	"II"	2.99412	"[C.elegansII] mn99 : embryonic lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-247"	"II"	3.3878	"[C.elegansII] mn211 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-248"	"II"	3.07756	"[C.elegansII] mn237 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-249"	"II"	3.87281	"[C.elegansII] mn238 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-250"	"II"	3.68689	"[C.elegansII] mn207 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-251"	"II"	5.78824	"[C.elegansII] mn95 : embryonic lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-252"	"II"	0.799813	"[C.elegansII] mn100 : embryonic lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-253"	"II"	0.49	"[C.elegansII] mn181 : larval lethal\; some embryonic and larval death or very slow growth to Egl adult.Severe constipation\; most intestinal nuclei fail to divide in L1.  OA2: mn184, n2142. Cloned: cosmid rescue (F31B8). [Sigurdson et al. 1984\; SP\; ML]"	
"let-257"	"II"	24	"[C.elegansII] mn235 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-259"	"II"	22.9302	"[C.elegansII] mn210 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-263"	"II"	0.203568	"[C.elegansII] mn240 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-264"	"II"	-0.140388	"[C.elegansII] mn227 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-265"	"II"	-0.268909	"[C.elegansII] mn188 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-266"	"II"	5.78824	"[C.elegansII] mn194 : larval lethal. NA1. [Sigurdson et al. 1984\; SP]"	
"let-268"	"II"	1.85236	"[C.elegansII] mn189 : larval lethal. OA1: mn198. [Sigurdson et al. 1984\; SP]"	
"let-272"	"IV"	-3.39686	"[C.elegansII] m243 : mid-larval lethal. OA1: m266. [DR]"	
"let-273"	"IV"	-2.88217	"[C.elegansII] m263 : early larval lethal. NA1. [Rogalski and Riddle 1988\; DR]"	
"let-274"	"IV"	-1.66302	"[C.elegansII] m256 : early larval lethal. NA1. [Rogalski and Riddle 1988\; DR]"	
"let-275"	"IV"	-0.554341	"[C.elegansII] m245 : mid-larval lethal. OA1 (m257). [Rogalski and Riddle 1988\; DR]"	
"let-276"	"IV"	0.603953	"[C.elegansII] m240 : early larval lethal. OA5: m239  (embryonic lethal), etc. [Rogalski and Riddle 1988\; DR]"	
"let-277"	"IV"	1.42574	"[C.elegansII] m262 : nonconditional constitutive formation of abnormal dauer-like larvae, arrested. OA1 (m657)[Rogalski and Riddle 1988\; DR]"	
"let-278"	"IV"	-0.065217	"[C.elegansII] m265 : sterile adult. NA1. [Rogalski and Riddle 1988\; DR]"	
"let-279"	"IV"	0.679447	"[C.elegansII] m261 : sterile adult. NA1. [Rogalski and Riddle 1988\; DR]"	
"let-280"	"IV"	1.40167	"[C.elegansII] m259 : sterile adult. NA1. [Rogalski and Riddle 1988\; DR]"	
"let-281"	"IV"	1.29333	"[C.elegansII] m247 : sterile adult. NA1. [Rogalski and Riddle 1988\; DR]"	
"let-282"	"IV"	1.29333	"[C.elegansII] m258 : early larval lethal.  OA1: m270  (sterile adult). [Rogalski and Riddle 1988\; DR]"	
"let-284"	"IV"	1.29333	"[C.elegansII] m267 : early larval lethal. NA1[Rogalski and Riddle 1988\; DR]"	
"let-288"	"IV"	0.609092	"[C.elegansII] m306 : sterile adult. NA1. [Rogalski and Riddle 1988\; DR]"	
"let-289"	"IV"	3.23624	"[C.elegansII] s1133 : embryonic or early larval lethal.  OA2: s1253, s2006. [BC\; DR]"	
"let-290"	"IV"	3.17017	"[C.elegansII] s1140 : embryonic or early larval lethal. OA1 (s1109?). [BC\; DR]"	
"let-291"	"IV"	3.31552	"[C.elegansII] s1139 : embryonic or early larval lethal. NA1. [BC\; DR]"	
"let-292"	"IV"	3.40801	"[C.elegansII] s1146 : embryonic or early larval lethal. NA1. [BC\; DR]"	
"let-293"	"IV"	3.09089	"[C.elegansII] s1166 : embryonic or early larval lethal.  NA1. [BC\; DR]"	
"let-294"	"IV"	3.42122	"[C.elegansII] s1103 : embryonic or early larval lethal. NA1. [BC\; DR]"	
"let-295"	"IV"	3.2032	"[C.elegansII] s1175 : embryonic or early larval lethal. NA1. [BC\; DR]"	
"let-296"	"IV"	3.40801	"[C.elegansII] s1250 : embryonic or early larval lethal. NA1. [BC\; DR]"	
"let-297"	"IV"	3.42122	"[C.elegansII] s1989 : embryonic or early larval lethal. NA1. [BC\; DR]"	
"let-301"	"IV"	7.74631	"[C.elegansII] s1134 : early larval lethal.  OA1: s1735. [Charest et al. 1990\; BC]"	
"let-302"	"IV"	6.88111	"[C.elegansII] s1159 : (lost) embryonic or early larval [Charest et al. 1990\; BC]"	
"let-307"	"IV"	4.63072	"[C.elegansII] s1171 : mid-larval lethal, s1171\/Df similar. NA1. [Clark et al. 1988\; BC]"	
"let-308"	"IV"	4.63072	"[C.elegansII] s1705 : mid-larval lethal, s1705\/Df similar.  NA1. [Clark et al. 1988\; BC]"	
"let-309"	"IV"	5.79858	"[C.elegansII] s1115 : late larval lethal, s1115\/Df similar.  OA1: s1770 (similar). [Clark et al. 1988\; Clark and Baillie 1992\; BC]"	
"let-311"	"IV"	4.89069	"[C.elegansII] s1195 : late larval lethal, s1195\/Df similar.  NA1. [Clark et al. 1988\; BC]"	
"let-312"	"IV"	4.69385	"[C.elegansII] s1234 : late larval lethal, s1234\/Df similar.  NA1. [Clark et al. 1988\; BC]"	
"let-313"	"IV"	9.4985	"[C.elegansII] s1135 : hemizygote is sterile adult.  NA1. [Charest et al. 1990\; BC]"	
"let-314"	"IV"	7.77782	"[C.elegansII] s1206 : hemizygote is embryonic or early larval lethal. NA1. [Charest et al. 1990\; BC]"	
"let-315"	"IV"	8.00499	"[C.elegansII] s1101 : hemizygote is mid-larval lethal, s1101 similar.  NA1. [Charest et al. 1990\; BC]"	
"let-316"	"IV"	7.83221	"[C.elegansII] s1227 : hemizygote is early larval lethal. NA1. [Charest et al. 1990\; BC]"	
"let-317"	"IV"	7.8081	"[C.elegansII] s1153 : hemizygote is embryonic or early larval lethal.  NA1. [Charest et al. 1990\; BC]"	
"let-318"	"IV"	9.4985	"[C.elegansII] s1218  : hemizygote is sterile adult.  NA1. [Charest et al. 1990\; BC]"	
"let-319"	"IV"	9.4985	"[C.elegansII] s1754 : late larval lethal, s1754\/Df similar.  OA1: s1233. [Charest et al. 1990\; BC]"	
"let-320"	"IV"	8.87567	"[C.elegansII] s1248 : hemizygote is sterile adult.OA1: s1757 (similar). [Charest et al. 1990\; BC]"	
"let-321"	"IV"	9.4985	"[C.elegansII] s1228 : hemizygote is sterile adult. NA1. [Charest et al. 1990\; BC]"	
"let-322"	"IV"	9.1426	"[C.elegansII] s1238 : hemizygote is early to mid larval lethal. NA1. [Charest et al. 1990\; BC]"	
"let-323"	"IV"	10.6615	"[C.elegansII] s1719 : sterile adult, s1719\/Df similar.  NA1. [Charest et al. 1990\; BC]"	
"let-324"	"IV"	9.52362	"[C.elegansII] s1727 : early larval lethal, s1727\/Df similar. NA1. [Charest et al. 1990\; BC]"	
"let-325"	"IV"	7.8165	"[C.elegansII] s1738 : mid-larval lethal, s1738\/Df sterile adult.  NA1. [Charest et al. 1990\; BC]"	
"let-326"	"V"	-19.363	"[C.elegansII] s1404 : early larval lethal.  OA1: s238 (mid larval lethal). [Johnsen and Baillie 1991\; BC]"	
"let-327"	"V"	-16.0774	"[C.elegansII] s247 : cold-sensitive larval lethal\;slow developer, translucent adult.  OA3: s1485, s1496 (morphological abnormalities, lethal 25C),  s1799. [Johnsen and Baillie 1991\; BC]"	
"let-329"	"V"	-0.545736	"[C.elegansII] s575 : early larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-330"	"V"	-11.571	"[C.elegansII] s573 : mid-larval lethal.  Highly mutable,  NA18: s1425 (early larval lethal), s1429, s1463, s1468, s1497, s1515, s1517, s1518, s1583, s1638, s1702spo, s955, etc.Also s1433, s1497, s1518 (anomalous complementation, possible weaker alleles). [Johnsen and Baillie 1991\; BC]"	
"let-331"	"V"	-2.85759	"[C.elegansII] s427 : cs mid-larval lethal or sterile adult.  OA1: s1608 (slow development, sterile). [Johnsen and Baillie 1991\; BC]"	
"let-332"	"V"	0.610222	"[C.elegansII] s234 : embryonic lethal.  OA6: s369, s1021 (some escapers), s1441, s1464 (late embryonic lethal), s1498, s1567. [Johnsen and Baillie 1991\; BC]"	
"let-334"	"V"	1.64955	"[C.elegansII] s908 : early larval lethal.  OA1: s383 (mid larval lethal). [Johnsen and Baillie 1991\; BC]"	
"let-335"	"V"	0.901913	"[C.elegansII] s1439 : early larval lethal.  OA5: s232, s1412, s1476 (tends to coil), s1520 (escapers to sterile Evl adult), s1523. [Johnsen and Baillie 1991\; BC]"	
"let-336"	"V"	-22.2	"[C.elegansII] s1413 : early larval lethal.  OA2: s1420, s1495. [Johnsen and Baillie 1991\; BC]"	
"let-337"	"V"	0.008217	"[C.elegansII] s825 : mid-larval lethal. OA4: s1426 (early larval lethal), s382, s1018, s1024. Some alleles early larval lethal, some Mel. [Johnsen and Baillie 1991\; BC]"	
"let-338"	"V"	-8.33	"[C.elegansII] s1020: mid-larval lethal.  OA1: s503gri (similar)[Johnsen and Baillie 1991\; BC]"	
"let-339"	"V"	0.610222	"[C.elegansII] s1444 : early larval lethal.  OA2: s1019 (cs Mel),s1469 (variable, embryonic to mid larval lethal). [Johnsen and Baillie 1991\; BC]"	
"let-340"	"V"	1.64955	"[C.elegansII] s1508 : early larval lethal. OA1: s1022 (mid larval lethal). [Johnsen and Baillie 1991\; BC]"	
"let-341"	"V"	-5.34533	"[C.elegansII] s1031 : embryonic  lethal.  OA>8: s1415, s1421, s1454, s1516, s1534, s1571, s2118fdi, ut58 (early larval lethal, Clr phenotype), n1613ts (variable vulvaless phenotype at 25C, some suppression by let-60(gf))[Johnsen and Baillie 1991\; BC\; JC\; MT]"	
"let-342"	"V"	-4.95508	"[C.elegansII] s1029 : early larval lethal, s1029\/sDf27 similar,s1029\/sDf50 is sterile adult.  OA4: s1487, s1549, s1616, s1442 (weaker allele, s1442\/sDf50 is viable).  Some alleles mid larval lethal. [Johnsen and Baillie 1991\; BC]"	
"let-343"	"V"	0.610222	"[C.elegansII] s1025 : embryonic lethal. OA5: s816, s1410, s1428, s1579, s1465  (cs slow development),[Johnsen and Baillie 1991\; BC]"	
"let-344"	"V"	-5.83746	"[C.elegansII] s376 : embryonic lethal. OA1: s1555 (mid larval lethal). [Johnsen and Baillie 1991\; BC]"	
"let-345"	"V"	-4.57109	"[C.elegansII] s578 : mid larval lethal.  OA4: s1452, s1509, s1510, s1690fdi.  Some alleles late larval lethal. [Johnsen and Baillie 1991\; BC]"	
"let-346"	"V"	0.610222	"[C.elegansII] s1619 : mid-larval lethal.  OA6: s373, s1026, s1575, s1580 (mid\/late larval lethal, Evl), s1630 (sterile adult, rescued by mating), s2166fdi. [Johnsen and Baillie 1991\; BC]"	
"let-347"	"V"	-11.5988	"[C.elegansII] s1035 : late larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-348"	"V"	-5.66822	"[C.elegansII] s1436 : early larval lethal. OA3: s1622 (resembles s1436), s998gri, s1448 (slow development to Mel adult, embryonic lethal), s1622. [Johnsen and Baillie 1991\; BC]"	
"let-349"	"V"	-0.694133	"[C.elegansII] s217 : early larval lethal.  OA3: s502gri, s572 (cold sensitive, late larval lethal), s1965uvi. [Johnsen and Baillie 1991\; BC]"	
"let-350"	"V"	-2.72208	"[C.elegansII] s250 : sterile adult.  OA1: s2126fdi. [Johnsen and Baillie 1991\; BC]"	
"let-351"	"I"	-0.6	"[C.elegansII] h43 : mid-larval lethal.  NA1. [Howell et al. 1987\; McKim et al. 1992\; KR]"	
"let-352"	"I"	-0.158593	"[C.elegansII] h45 : late larval lethal\/sterile adult. NA1. [Howell et al. 1987\; KR]"	
"let-353"	"I"	-1.46646	"[C.elegansII] h46 : mid-larval lethal. NA1. [Howell and Rose 1990\; KR]"	
"let-354"	"I"	-1.33944	"[C.elegansII] h79 : mid-larval lethal, no dominant effect.  OA>20 (recessive lethals), also 3 dominant alleles: ct42, ct76, ct77 (all 3 alleles lead to recessive zygotic larval lethality, dominant embryonic Mel). [Howell and Rose 1990\; Mains et al. 1990\; HR\; KR]"	
"let-355"	"I"	0.000148	"[C.elegansII] h81 : sterile adult.  NA1. [Howell et al. 1987\; KR]"	
"let-356"	"I"	-2.20819	"[C.elegansII] h83 : mid-larval lethal.  OA3: h501, h679, h871. [Howell and Rose 1990\; KR]"	
"let-357"	"I"	-3.12285	"[C.elegansII] h89 : sterile adult.  OA1: h132. [Howell et al. 1987\; KR]"	
"let-359"	"I"	-0.241793	"[C.elegansII] h94 : sterile adult. NA1. [Howell et al. 1987\; KR]"	
"let-360"	"I"	-5.13219	"[C.elegansII] h96 : late larval lethal. NA1. [Howell et al. 1987\; KR]"	
"let-361"	"I"	-0.237052	"[C.elegansII] h97 : late larval\/early adult lethal. OA3: h113, h116, h323gri. [Howell et al. 1987\; KR]"	
"let-362"	"I"	-13.2735	"[C.elegansII] h86 : embryonic lethal.  OA1: h93. [Howell et al. 1987\; KR]"	
"let-363"	"I"	-0.237171	"[C.elegansII] h98 : late larval lethal.  OA4: h111 (early adult arrest), h60, h114, h131 (lethal). [Howell et al. 1987\; KR]"	
"let-364"	"I"	-0.245386	"[C.elegansII] h104 : sterile adult.  NA1. [Howell et al. 1987\; KR]"	
"let-365"	"I"	-5.30737	"[C.elegansII] h108 : sterile adult.  OA2: h129, h295 (sterile adult). [Howell et al. 1987\; KR]"	
"let-366"	"I"	-1.77851	"[C.elegansII] h112 : mid-larval lethal.  OA6: h265 (lethal), etc. [Howell and Rose 1990\; KR]"	
"let-367"	"I"	0.010253	"[C.elegansII] h119 : sterile adult. NA1. Cloned: cosmid rescue (C12H4). [Howell et al. 1987\; KR]"	
"let-368"	"I"	-2.7	"[C.elegansII] h121 : early larval lethal.  OA1:h826 (sterile adult, not rescued by mating). [Howell et al. 1987\; KR]"	
"let-369"	"I"	-2.22013	"[C.elegansII] h125 : early larval lethal.  OA1: h864 (mid larval lethal). [Howell et al. 1987\; KR]"	
"let-370"	"I"	-0.006033	"[C.elegansII] h128 : sterile adult or Mel with larval lethality. OA1: h210. [Howell et al. 1987\; KR]"	
"let-371"	"I"	-0.2	"[C.elegansII] h123 : mid- to late larval lethal\/sterile adult. NA1. [Howell et al. 1987\; KR]"	
"let-372"	"I"	-2.6	"[C.elegansII] h126 : sterile adult.  NA1. [Howell et al. 1987\; KR]"	
"let-373"	"I"	-1.86206	"[C.elegansII] h234 : early larval lethal.  OA2: h70, h573 (early larval lethal). [Howell and Rose 1990\; KR]"	
"let-374"	"I"	-1.46213	"[C.elegansII] h251 : mid-larval lethal. NA1. [Howell and Rose 1990\; KR]"	
"let-375"	"I"	-0.609294	"[C.elegansII] h259 : leaky sterile adult. OA1: h391 (similar)[Howell and Rose 1990\; KR]"	
"let-376"	"I"	0.26	"[C.elegansII] h130 : early larval lethal. OA6: h416 (lethal), etc. Cloned: cosmid rescue (M01A12) [Howell et al. 1987\; KR]"	
"let-377"	"I"	0.29	"[C.elegansII] h110 : early larval lethal. OA2: h443, h766[Howell et al. 1987\; KR]"	
"let-378"	"I"	0.27	"[C.elegansII] h124 : sterile adult. OA3: h181, h401, h563. Cloned: cosmid rescue (C07F10)[Howell et al. 1987\; KR]"	
"let-379"	"I"	0.28	"[C.elegansII] h127 : embryonic or early larval lethal. OA2: h186, h712. [Howell et al. 1987\; KR]"	
"let-380"	"I"	0.950025	"[C.elegansII] h80 : late larval lethal.  OA2: h675, h831. [Howell et al. 1987\; KR]"	
"let-381"	"I"	0.905292	"[C.elegansII] h107 : embryonic or early larval lethal. OA2: h495, h747. Cloned (cosmid F26B1).  [Howell et al. 1987\; KR]"	
"let-382"	"I"	1.23975	"[C.elegansII] h82 : mid-larval lethal.  OA1: h476. [Howell et al. 1987\; KR]"	
"let-383"	"I"	1.29	"[C.elegansII] h115 : early to mid-larval lethal.  OA3: h389, h527, h727. [Howell et al. 1987\; [McKim et al. 1992\; KR]"	
"let-384"	"I"	0.746054	"[C.elegansII] h84 : late larval lethal or sterile adult. OA3: h388, h454, h865. [Howell et al. 1987\; KR]"	
"let-385"	"I"	1.36407	"[C.elegansII] h85 : early larval lethal.  Highly mutable:OA>15: h578 (spontaneous, late larval lethal),h940, etc. [Howell et al. 1987\; McKim et al. 1992\; KR]"	
"let-386"	"I"	1.20492	"[C.elegansII] h117 : mid-larval lethal.  OA4: h678, etc. [Howell et al. 1987\; KR]"	
"let-387"	"I"	0.909183	"[C.elegansII] h87 : mid- to late larval lethal. OA1: h183. [Howell et al. 1987\; KR]"	
"let-388"	"I"	0.421973	"[C.elegansII] h88 : early larval lethal.  OA2: h729, h843. [Howell et al. 1987\; KR]"	
"let-389"	"I"	1.57186	"[C.elegansII] h680 : early larval lethal.  OA10: h428, h106 (both early larval lethal), h698 (late larval lethal).  Complex complementation, h698\/h428 is fertile. [Howell et al. 1987\; McKim et al. 1992\; KR]"	
"let-390"	"I"	1.23975	"[C.elegansII] h44 : late larval lethal or sterile adult.  NA1. [Howell et al. 1987\; KR]"	
"let-391"	"I"	0.878323	"[C.elegansII] h91 : late larval lethal or sterile adult. OA3:h823 (early\/mid larval lethal), h736, h475. [Howell et al. 1987\; KR]"	
"let-392"	"I"	1.27	"[C.elegansII] h120 : early larval lethal.  OA8: h122 etc. [Howell et al. 1987\; McKim et al. 1992\; KR]"	
"let-393"	"I"	0.005074	"[C.elegansII] h225 : early larval lethal.  OA1: h375 etc. Cloned: cosmid rescue (F40D12)."	
"let-394"	"I"	1.40386	"[C.elegansII] h262 : early to mid-larval lethal. OA6:h361 (sterile adult), etc. Cloned: cosmid rescue (T14D10). [McKim et al. 1992\; KR]"	
"let-395"	"I"	0.25	"[C.elegansII] h271 : sterile adult, undeveloped gonad.  NA1. Cloned: partial cosmid rescue (M01A12),to Mel with arrest at cleavage stage. [KR]"	
"let-396"	"I"	0.89159	"[C.elegansII] h217 : early larval lethal. OA4: h354 etc. [KR]"	
"let-397"	"I"	1.24124	"[C.elegansII] h228 : early larval lethal.  OA2: h221, h445. [McKim et al. 1992\; KR]"	
"let-398"	"I"	1.31431	"[C.elegansII] h257 : arrests L2. NA1. Cloned: partial cosmid rescue (K01B11)[McKim et al. 1992\; KR]"	
"let-399"	"I"	1.34652	"[C.elegansII] h273 : L4 lethal.  NA1. [McKim et al. 1992\; KR]"	
"let-400"	"I"	1.58146	"[C.elegansII] h269 : early to mid-larval lethal.  OA5: h878, h590gri, etc. [McKim et al. 1992\; KR]"	
"let-401"	"V"	-0.755489	"[C.elegansII] s193 : mid-larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-402"	"V"	-0.232065	"[C.elegansII] s1526 : early larval lethal.  OA2: s127(mid-larval lethal), s500gri. [Johnsen and Baillie 1991\; BC]"	
"let-403"	"V"	-0.09675	"[C.elegansII] s1482: early larval lethal.  OA3: s120(mid\/late larval lethal), s246, s498gri. [Johnsen and Baillie 1991\; BC]"	
"let-404"	"V"	0.478088	"[C.elegansII] s119 : mid-larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-405"	"V"	0.899563	"[C.elegansII] s116 : early larval lethal. OA2: s388, s829. Some alleles mid larval lethal. [Johnsen and Baillie 1991\; BC]"	
"let-406"	"V"	0.746919	"[C.elegansII] s514 : mid-larval lethal (gri).  NA1. Cloned: cosmid rescue (F58G4). [Johnsen and Baillie 1991\; BC]"	
"let-407"	"V"	1.88048	"[C.elegansII] s830 : early larval lethal.  OA3: s118,s1631 (early larval lethal), s2122fdi. [Johnsen and Baillie 1991\; BC]"	
"let-408"	"V"	0.909954	"[C.elegansII] s827 : embryonic lethal.  OA1: s195 (late larval lethal).  [Johnsen and Baillie 1991\; BC]"	
"let-409"	"V"	1.54397	"[C.elegansII] s823 : early larval lethal.  OA6: s206 (early larval lethal), s1480 (early larval lethal, curls), s1507, s1528, s1546, s1547). [Johnsen and Baillie 1991\; BC]"	
"let-410"	"V"	0.408469	"[C.elegansII] s815 : mid-larval lethal.  OA1: s1565 (similar). [Johnsen and Baillie 1991\; BC]"	
"let-411"	"V"	0.766054	"[C.elegansII] s1595 : mid-larval lethal.  OA3: s223 (late larval lethal), s1453, s1553. [Johnsen and Baillie 1991\; BC]"	
"let-412"	"V"	1.51493	"[C.elegansII] s1598 : sterile adult roller.  OA1: s579 (Mel, embryonic lethality)[Johnsen and Baillie 1991\; BC]"	
"let-413"	"V"	1.30398	"[C.elegansII] s128 : embryonic lethal.  OA3: s1431, s1451, s1455.  [Johnsen and Baillie 1991\; BC]"	
"let-414"	"V"	0.909954	"[C.elegansII] s114 : mid-larval lethal.  OA1: s207. [Johnsen and Baillie 1991\; BC]"	
"let-415"	"V"	-1.59818	"[C.elegansII] s1525 : early larval lethal. OA2: s1505 (late larval lethal), s129 (mid\/late larval lethal). [Johnsen and Baillie 1991\; BC]"	
"let-416"	"V"	1.54397	"[C.elegansII] s113 : late larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-417"	"V"	-0.945589	"[C.elegansII] s204 : early larval lethal.  OA3: s1313, s1424, s1679fdi). [Johnsen and Baillie 1991\; BC]"	
"let-418"	"V"	-0.65495	"[C.elegansII] s1617 : sterile adult, Evl, partial rescue 15C.OA1: s1045 (sterile Evl adult 24C, Mel (early larval lethal) at 20C). [Johnsen and Baillie 1991\; BC]"	
"let-419"	"V"	-2.59398	"[C.elegansII] s1483 : early\/mid larval lethal.  OA2: s219 (mid-larval lethal), s1539. [Johnsen and Baillie 1991\; BC]"	
"let-420"	"V"	-2.72208	"[C.elegansII] s1046 : sterile adult, Evl.  OA6: s723gri,s1058, s1478, s1573, s1584, s1603 (abnormal tail). [Johnsen and Baillie 1991\; BC]"	
"let-421"	"V"	-0.65495	"[C.elegansII] s1477 : embryonic lethal.  OA3: s288 (leaky),s1460 (dumpy, mid-larval lethal), s1632 (dumpy, curls, escapers late larval lethal, Evl). [Johnsen and Baillie 1991\; BC]"	
"let-422"	"V"	-0.677123	"[C.elegansII] s194 : early larval lethal. OA6: s738gri,s739gri, s1312, s1563, s1578 (ts, rescued 15C), s1548. [Johnsen and Baillie 1991\; BC]"	
"let-423"	"V"	0.825997	"[C.elegansII] s818 : early larval lethal. OA1: s1550  (early\/mid larval lethal). [Johnsen and Baillie 1991\; BC]"	
"let-424"	"V"	1.10697	"[C.elegansII] s384 : sterile adult.  OA2: s248, s1587 (similar). [Johnsen and Baillie 1991\; BC]"	
"let-425"	"V"	0.610222	"[C.elegansII] s385 : sterile adult. NA1. [Johnsen and Baillie 1991\; BC]"	
"let-426"	"V"	-17.796	"[C.elegansII] s1527 : early larval lethal. OA1: s826 (mid-larval lethal). [Johnsen and Baillie 1991\; BC]"	
"let-427"	"V"	2.08903	"[C.elegansII] s1057 : sterile adult.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-428"	"V"	-2.72208	"[C.elegansII] s1490 : dumpy, late larval lethal (ruptures).  OA1: s1070  (sterile adult). [Johnsen and Baillie 1991\; BC]"	
"let-429"	"V"	-0.393001	"[C.elegansII] s584 : sterile adult.  OA1: s1597  (slow development, morphological abnormalities). [Johnsen and Baillie 1991\; BC]"	
"let-430"	"V"	-5.66822	"[C.elegansII] s1042 : sterile adult.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-431"	"V"	-19.8968	"[C.elegansII] s1049 : sterile adult.  OA1: s1044 (similar). [Johnsen and Baillie 1991\; BC]"	
"let-433"	"V"	1.53966	"[C.elegansII] s950 : sterile adult.  NA1. Cloned: cosmid rescue F25G6 [Johnsen and Baillie 1991\; BC]"	
"let-434"	"V"	1.46996	"[C.elegansII] s1904 : sterile adult, gri. NA1. Cloned: cosmid rescue (ZK307). [Johnsen and Baillie 1991\; BC]"	
"let-436"	"V"	1.10697	"[C.elegansII] s1403 : early larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-437"	"V"	-20.9542	"[C.elegansII] s1405 : mid larval lethal, abnormal tail. NA1. [Johnsen and Baillie 1991\; BC]"	
"let-438"	"V"	0.610222	"[C.elegansII] s2114 : fdi, lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-439"	"V"	-0.393001	"[C.elegansII] s1407 : early larval lethal.  OA3: s1503,s1522, s1524 (all similar) [Johnsen and Baillie 1991\; BC]"	
"let-440"	"V"	-2.72208	"[C.elegansII] s1411 : very early larval lethal.  OA4: s1440, s1552, s1560, s1589 (similar). [Johnsen and Baillie 1991\; BC]"	
"let-441"	"V"	2.03696	"[C.elegansII] s1414 : early larval lethal (ts, leaky at 20C,rescued at 15C).  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-442"	"V"	0.610222	"[C.elegansII] s1416 : early\/mid larval lethal.  OA2: s1430ts (partial rescue to sterile adult at 15C),s1535. [Johnsen and Baillie 1991\; BC]"	
"let-443"	"V"	-0.85112	"[C.elegansII] s1417 : early larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-444"	"V"	-0.166016	"[C.elegansII] s1418 : early larval lethal.  OA2: s1459,s1569 (Mel). [Johnsen and Baillie 1991\; BC]"	
"let-445"	"V"	1.10697	"[C.elegansII] s1419 : Mel (larval lethal, tight coiler). [Johnsen and Baillie 1991\; BC]"	
"let-447"	"V"	-21.9486	"[C.elegansII] s1457 : Mel, (embryonic lethal, arrest pre-lima bean),s1457\/Df lays more eggs than homozygote. OA1: s1654fdi (resembles s1457)[Johnsen and Baillie 1991\; BC]"	
"let-448"	"V"	-21.4235	"[C.elegansII] s1363mut : mid\/late larval lethal. NA1. [Johnsen and Baillie 1991\; BC]"	
"let-449"	"V"	0.825966	"[C.elegansII] s1343mut : early larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-450"	"V"	-22.6	"[C.elegansII] s2160 : fdi, lost. [Johnsen and Baillie 1991\; BC]"	
"let-452"	"V"	-2.72208	"[C.elegansII] s1434 : early larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-453"	"V"	-20.4388	"[C.elegansII] s2167 : lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-454"	"V"	2.03696	"[C.elegansII] s1423 : mid larval lethal\; double cuticle, no pumping.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-455"	"V"	-8.34	"[C.elegansII] s1447 : early larval lethal.  OA1: s1511 (similar). [Johnsen and Baillie 1991\; BC]"	
"let-456"	"V"	1.30828	"[C.elegansII] s1479 : early larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-458"	"V"	-21.9486	"[C.elegansII] s1443 : early larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-459"	"V"	-6.44318	"[C.elegansII] s1432 : mid larval lethal.  OA1: s1615 (Mel (embryonic lethal), not rescued by mating). [Johnsen and Baillie 1991\; BC]"	
"let-460"	"V"	1.76107	"[C.elegansII] s1664 : early larval lethal, fdi.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-462"	"V"	-0.393001	"[C.elegansII] s1594 : embryonic\/early larval lethal.  OA3: s1481 (larval lethal, molting problem), s1590, s1956uvi. [Johnsen and Baillie 1991\; BC]"	
"let-463"	"V"	-0.545736	"[C.elegansII] s2168 : lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-464"	"V"	1.43685	"[C.elegansII] s1504 : embryonic\/early larval lethal.  OA1: s1530 (early larval lethal). [Johnsen and Baillie 1991\; BC]"	
"let-466"	"V"	-8.35	"[C.elegansII] s1063 : Mel (early larval lethal).  OA1: s990 (Mes, maternal effect sterile). [Johnsen and Baillie 1991\; BC]"	
"let-467"	"V"	1.70613	"[C.elegansII] s1521 : early larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-468"	"V"	0.610222	"[C.elegansII] s1533 : early larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-469"	"V"	0.408469	"[C.elegansII] s1582 : sterile adult, rescued by mating.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-470"	"V"	1.97236	"[C.elegansII] s1581 : mid larval lethal.  OA1: s1629ts (slow development 20C, normal 15C). [Johnsen and Baillie 1991\; BC]"	
"let-471"	"V"	0.408469	"[C.elegansII] s1570 : Mel (early larval lethal, rescued by mating).  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-472"	"V"	0.408469	"[C.elegansII] s1605 : mid larval lethal, morphological abnormalities.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-473"	"V"	-0.240267	"[C.elegansII] s1602 : early larval lethal, trapped in old cuticle.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-474"	"V"	0.766054	"[C.elegansII] s1577 : early larval lethal.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-475"	"V"	1.97236	"[C.elegansII] s1606 : sterile adult. NA1. [Johnsen and Baillie 1991\; BC]"	
"let-476"	"V"	-0.040158	"[C.elegansII] s1621 : ts, sterile adult at 20C, rescued by mating\;fertile at 15C. NA1. [Johnsen and Baillie 1991\; BC]"	
"let-478"	"V"	-9.01513	"[C.elegansII] s1620 : early larval lethal, s1620\/sDf50 is Mel(embryonic lethal).  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-479"	"V"	-0.393001	"[C.elegansII] s1576 : sterile Evl adult, lays unfertilized eggs\;rescued by mating\; partial rescue at 15C.  NA1. [Johnsen and Baillie 1991\; BC]"	
"let-501"	"I"	-1.91577	"[C.elegansII] h714 : early larval lethal. OA1: h498  (mid larval lethal). [Howell and Rose 1990\; KR]"	
"let-502"	"I"	-1.4	"[C.elegansII] h392 :  mid larval lethal. OA5:h783 (late larval lethal), h509 (sterile adult), ca201sd (embryonic arrest, early morphogenesis\; ca201\/+ sometimes abnormal), h732, h835(both mid-larval lethal).All alleles probable dominant negatives. Cloned : encodes protein with similarity to human mytotonic dystrophy kinase. [Howell and Rose 1990\; HR\; JM\; KR]"	
"let-503"	"I"	-1.4648	"[C.elegansII] h313 : sterile adult. OA1: h418 (similar). [Howell and Rose 1990\; KR]"	
"let-504"	"I"	-1.54025	"[C.elegansII] h844 : late larval lethal.  OA3:h448 (sterile adult), h327, h888 (late larval lethals). [Howell and Rose 1990\; KR]"	
"let-505"	"I"	-1.54025	"[C.elegansII] h426 : late larval lethal. NA1. [Howell and Rose 1990\; KR]"	
"let-506"	"I"	-1.46646	"[C.elegansII] h300 : late larval lethal.  NA1. [Howell and Rose 1990\; KR]"	
"let-507"	"I"	-1.4649	"[C.elegansII] h439 : leaky sterile adult.  NA1. [Howell and Rose 1990\; KR]"	
"let-508"	"I"	-0.944638	"[C.elegansII] h452 : late larval lethal.  OA1: h995. [Howell and Rose 1990\; KR]"	
"let-509"	"I"	-1.91577	"[C.elegansII] h867 : leaky late larval lethal\/sterile adult.OA2: h521 (leaky sterile adult), h522. [Howell and Rose 1990\; KR]"	
"let-510"	"I"	-1.91577	"[C.elegansII] h740 : lethal. NA1. [Howell and Rose 1990\; KR]"	
"let-511"	"I"	-1.91577	"[C.elegansII] h755 : early larval lethal.  NA1. [Howell and Rose 1990\; KR]"	
"let-512"	"I"	0.630011	"[C.elegansII] h797 :  Mid-larval lethal. OA5: h351, etc. [KR]"	
"let-513"	"I"	0.539066	"[C.elegansII] h752 : sterile adult. NA1. [KR]"	
"let-514"	"I"	0.45	"[C.elegansII] h753 : early\/mid larval lethal. NA1. Cloned: partial cosmid rescue (C32E7),to sterile adult, no oocytes. [KR]"	
"let-515"	"I"	-2.78316	"[C.elegansII] h730 : early larval lethal.  OA3:h223 (late larval lethal), h139, h149 (both Mel). [KR]"	
"let-517"	"I"	-2.49601	"[C.elegansII] h264 : lethal.  OA2: h757, h1398. [KR]"	
"let-518"	"I"	-2.49601	"[C.elegansII] h316 : embryonic\/early larval lethal.  NA1. [KR]"	
"let-519"	"I"	-0.293592	"[C.elegansII] h405 : lethal.  NA1. [KR]"	
"let-520"	"I"	1.65024	"[C.elegansII] h690 : L4 lethal.  OA1: h1003 (similar). [McKim et al. 1992\; KR]"	
"let-521"	"I"	1.3553	"[C.elegansII] h704 : L4 lethal.  NA1. [McKim et al. 1992\; KR]"	
"let-522"	"I"	1.73127	"[C.elegansII] h735 : early larval lethal.  OA2: h240, h519. [McKim et al. 1992\; KR]"	
"let-523"	"I"	1.73127	"[C.elegansII] h751 : early larval lethal.  OA1: h479. [McKim et al. 1992\; KR]"	
"let-524"	"I"	1.79	"[C.elegansII] h442 : early larval lethal.  OA4: h53gri, etc. [McKim et al. 1992\; KR]"	
"let-525"	"I"	1.73127	"[C.elegansII] h874 : mid larval lethal.  OA1: h410[McKim et al. 1992\; KR]"	
"let-527"	"I"	1.79	"[C.elegansII] h207 : early larval lethal.  OA3: h209 (mid larval lethal), h357 (some maternalrescue to Spe adult),  h932(early larval lethal). [McKim et al. 1992\; KR]"	
"let-528"	"I"	1.40537	"[C.elegansII] h1012 : late larval lethal.  OA1: h58spo (similar). [McKim et al. 1992\; KR]"	
"let-529"	"I"	1.35968	"[C.elegansII] h238 : early larval lethal.  OA3. [McKim et al. 1992\; KR]"	
"let-530"	"I"	0.24	"[C.elegansII] h798 : early larval lethal.  OA5: h359, etc. Cloned: partial cosmid rescue (M01A12)of h798, to Mel (cleavage arrest). [KR]"	
"let-531"	"I"	0.295266	"[C.elegansII] h733 : late larval lethal.  OA1: h767. [KR]"	
"let-532"	"I"	0.376975	"[C.elegansII] h715 : embryonic lethal.  NA1. Cloned: cosmid rescue (anomalous?). [KR]"	
"let-534"	"I"	1.31494	"[C.elegansII] h260 : mid larval lethal, coiler Unc. OA1: h196 (mid larval lethal). Cloned: cosmid rescue (T14D10). [McKim et al. 1992\; KR]"	
"let-535"	"I"	2.43916	"[C.elegansII] h993 : mid larval lethal.  OA1: h999 (similar). [McKim et al. 1992\; KR]"	
"let-536"	"I"	3.12183	"[C.elegansII] h882 : late larval lethal.  NA1. [McKim et al. 1992\; KR]"	
"let-538"	"I"	2.43916	"[C.elegansII] h990 : sterile adult.  NA1. [McKim et al. 1992\; KR]"	
"let-539"	"I"	1.83158	"[C.elegansII] h938 : mid larval lethal.  NA1. [McKim et al. 1992\; KR]"	
"let-540"	"I"	2.04276	"[C.elegansII] h884 : late larval lethal.  NA1. [McKim et al. 1992\; KR]"	
"let-541"	"I"	3.12183	"[C.elegansII] h886 : early larval lethal.  NA1. [KR]"	
"let-542"	"I"	1.94619	"[C.elegansII] h986 : early larval lethal.  NA1. [McKim et al. 1992\; KR]"	
"let-543"	"I"	1.37284	"[C.elegansII] h792 : L4 lethal.  NA1. [McKim et al. 1992\; KR]"	
"let-544"	"I"	1.27417	"[C.elegansII] h692 : sterile adult.  NA1. [McKim et al. 1992\; KR]"	
"let-545"	"I"	1.45378	"[C.elegansII] h842 : sterile adult, very few germ line nuclei, no oocytes or sperm.   NA1. Cloned: cosmid rescue (T21G5).  Possibly = glh-1. [McKim et al. 1992\; KR]"	
"let-546"	"I"	-15	"[C.elegansII] h227 : lethal.  NA1. [KR]"	
"let-547"	"I"	-15	"[C.elegansII] h277 : lethal.  NA1. [KR]"	
"let-548"	"I"	-11.3174	"[C.elegansII] h356 : lethal.  NA1. [KR]"	
"let-549"	"I"	-7.52689	"[C.elegansII] h193 : lethal.  NA1. [KR]"	
"let-550"	"I"	-2.65	"[C.elegansII] h291 : sterile adult.  NA1. [KR]"	
"let-551"	"V"	17.0688	"[C.elegansII] e2517 : early\/mid larval lethal at 20C,sterile adult at 15C, mutator induced. [CB]"	
"let-552"	"II"	-5.21291	"[C.elegansII] e2542 : most animals arrest as L1 hatchlings, small dumpy warped appearance. Occasional escapers reach fertile adulthood, with extreme dumpy phenotype, rare progeny have same phenotype\; spontaneous mutation.NA1. [CB]"	
"let-571"	"I"	-12.5	"[C.elegansII] h347 : lethal.  NA1. [KR]"	
"let-572"	"I"	-15	"[C.elegansII] h220 : lethal.  NA1. [KR]"	
"let-573"	"I"	-8.15342	"[C.elegansII] h247 : lethal.  NA1. [KR]"	
"let-574"	"I"	-2.65	"[C.elegansII] h317 : sterile adult.  NA1. [KR]"	
"let-575"	"I"	-2.65	"[C.elegansII] h345 : lethal.  OA1: h728. [KR]"	
"let-576"	"I"	-2.65	"[C.elegansII] h816 : early larval lethal.  OA1: h494. [KR]"	
"let-577"	"I"	-2.65	"[C.elegansII] h503 : early larval lethal.  NA1. [KR]"	
"let-578"	"I"	-2.65	"[C.elegansII] h512 : lethal.  NA1. [KR]"	
"let-579"	"I"	-2.65	"[C.elegansII] h705 : mid larval lethal.  NA1. [KR]"	
"let-580"	"I"	-2.65	"[C.elegansII] h709 : lethal.  NA1. [KR]"	
"let-581"	"I"	-2.65	"[C.elegansII] h725 : mid larval lethal.  OA1: h876 (similar). [KR]"	
"let-582"	"I"	-2.65	"[C.elegansII] h726 : lethal.  NA1. [KR]"	
"let-583"	"I"	-2.65	"[C.elegansII] h738 : early\/mid larval lethal.  NA1. [KR]"	
"let-584"	"I"	-2.65	"[C.elegansII] h743 : sterile adult.  OA1: h746 (similar). [KR]"	
"let-585"	"I"	-2.5	"[C.elegansII] h784 : early larval lethal.  NA1. [KR]"	
"let-587"	"I"	-2.65	"[C.elegansII] h849 : late larval lethal.  NA1. [KR]"	
"let-589"	"I"	-2	"[C.elegansII] h319 : Mel, embryonic arrest.  NA1. [KR]"	
"let-595"	"I"	-0.1	"[C.elegansII] h353 : lethal.  OA1: h372. [KR]"	
"let-598"	"I"	-0.3	"[C.elegansII] h213 : lethal.  OA1: h813. [KR]"	
"let-599"	"I"	-0.127284	"[C.elegansII] h290 : sterile adult.  NA1. [KR]"	
"let-601"	"I"	1.01	"[C.elegansII] h281 : embryonic lethal.  NA1. Cloned: cosmid rescue (ZC338). [KR]"	
"let-602"	"I"	0.886985	"[C.elegansII] h283 : early larval lethal.  OA2: h374, h497. Cloned: mixed cosmid rescue, (incl. C46H8),partial rescue to sterile adult, no oocytes. [KR][McDowall JS]"	
"let-603"	"I"	0.455	"[C.elegansII] h289 : sterile adult (gonad tumorous mass). OA3: h408, h437, h812 (sterile adults). Cloned: partial cosmid rescue (C32E7)\; rescued to Mel. [KR]"	
"let-604"	"I"	1.23766	"[C.elegansII] h293 : sterile adult.  OA1: h490 (similar). [KR]"	
"let-605"	"I"	1.30709	"[C.elegansII] h312 : sterile Unc adult.  h312\/Df sterile, Evl, strong coiler Unc.  OA4 (all alleles Unc). [McKim et al. 1992\; KR]"	
"let-607"	"I"	1.23978	"[C.elegansII] h402 : embryonic lethal.  NA1. [KR]"	
"let-608"	"I"	1.13204	"[C.elegansII] h706 : early larval arrest, lives 1-2 weeks. OA2. [KR]"	
"let-610"	"I"	1.13204	"[C.elegansII] h695 : sterile adult.  NA1. [KR]"	
"let-611"	"I"	0.89751	"[C.elegansII] h850 : early\/mid larval lethal.  OA2. Cloned: mixed cosmid rescue (incl. C48E7),rescue to sterile adult, no oocytes. [KR]"	
"let-613"	"I"	-0.8	"[C.elegansII] h198 : lethal.  NA1. [KR]"	
"let-651"	"IV"	4.66205	"[C.elegansII] s1165 : mid larval lethal.  OA1: s1185 (midlarval lethal, fails to complement let-91(s753)). [Clark and Baillie 1992\; BC]"	
"let-652"	"IV"	4.66205	"[C.elegansII] s1086 : mid larval lethal, s1086\/Df similar.  NA1. [Clark and Baillie 1992\; BC]"	
"let-653"	"IV"	5.39361	"[C.elegansII] s1733 : early larval lethal, arrest stage is late L1 to early L2\; cystic excretory canals. OA2: s2270 (homozygote arrests L2 with vacuole anterior to posterior pharyngeal bulb,hemizygote arrests L1), s2377 (homozygote sterile adult, hemizygote arrests L2). Cloned: encodes predicted 694 aa secreted protein, with features characteristic of mucin glycoproteins. [Jones and Baillie 1995\; BC\; NJ]"	
"let-655"	"IV"	4.98218	"[C.elegansII] s1748 : sterile adult, s1748\/Df similar.  NA1. [Clark and Baillie 1992\; BC]"	
"let-656"	"IV"	5.78324	"[C.elegansII] s1753 : sterile adult, s1753\/Df similar.  OA1: s1767 (similar). [Clark and Baillie 1992\; BC]"	
"let-657"	"IV"	4.59565	"[C.elegansII] s1254 : hemizygotes arrest embryo\/early larva.OA3: s1143, s1164, s1236. [BC]"	
"let-658"	"IV"	4.49349	"[C.elegansII] s1149 : hemizygote arrests as late larva.OA2: s1107, s1194. [BC]"	
"let-659"	"IV"	4.49349	"[C.elegansII] s1152 : hemizygote arrests as early larva.  NA1. [BC]"	
"let-660"	"IV"	5.36778	"[C.elegansII] s1996 : sterile adult (leaky). NA1. [BC]"	
"let-661"	"IV"	5.53699	"[C.elegansII] s2203 : homozygote and hemizygote arrest as L2 larva.  NA1. Cloned: partial cosmid rescue (K04H1). [BC]"	
"let-662"	"IV"	5.70541	"[C.elegansII] s2219 : homozygote and hemizygote arrest as leaky sterile adult.  NA1. [BC]"	
"let-664"	"IV"	5.34074	"[C.elegansII] s2374 : homozygote and hemizygote arrest as sterile adult.  NA1. [BC]"	
"let-702"	"III"	-0.75	"[C.elegansII] s2483 : early larval lethal.  NA1. [BC]"	
"let-705"	"III"	-1.47335	"[C.elegansII] s2451 : early larval lethal.  NA1. [BC]"	
"let-706"	"III"	-5.48258	"[C.elegansII] s2480 : early larval lethal.  NA1. [BC]"	
"let-707"	"III"	-2.31355	"[C.elegansII] s2462 : early larval lethal.  NA1. [BC]"	
"let-713"	"III"	-1.36	"[C.elegansII] s2449 : early\/mid larval lethal.  OA1: s2470 (early larval lethal). [BC]"	
"let-714"	"III"	-0.8	"[C.elegansII] s2582 : early larval lethal. OA2: s2481 (mid\/late larval lethal), s2465 (sterile). [BC]"	
"let-715"	"III"	-3.43	"[C.elegansII] s2618 : variable sterile adult.  NA1. [BC]"	
"let-716"	"III"	-1.33	"[C.elegansII] s2457 : early larval lethal.  OA1: s2626 (similar). [BC]"	
"let-720"	"III"	-20.5086	"[C.elegansII] s2610 : sterile adult.  NA1. [BC]"	
"let-721"	"III"	-1.34	"[C.elegansII] s2447 : sterile adult.  NA1. [BC]"	
"let-722"	"III"	-0.5	"[C.elegansII] s2448 : early larval lethal.  OA2: s2588 (pka let-744, mid larval lethal), s2450 (pka let-772, sterile adult). [BC]"	
"let-723"	"III"	-1.12857	"[C.elegansII] s2434 : sterile adult. NA1. [BC]"	
"let-725"	"III"	-1.38	"[C.elegansII] s2454 : sterile adult. NA1. [BC]"	
"let-728"	"III"	-1.41447	"[C.elegansII] s2573 : early\/mid larval lethal.  NA1. [BC]"	
"let-733"	"III"	-2.33	"[C.elegansII] s2467 : sterile adult.  NA1. [BC]"	
"let-733"	"III"	-2.33	"[C.elegansII] s2621 : variable sterile adult. NA1. [BC]"	
"let-734"	"III"	-2.1	"[C.elegansII] s2479 : early larval lethal. NA1. [BC]"	
"let-737"	"III"	-4	"[C.elegansII] s2477 : mid larval lethal.  NA1. [BC]"	
"let-747"	"III"	-1.2841	"[C.elegansII] s2456 : early\/mid larval lethal.  NA1. [BC]"	
"let-754"	"III"	-0.5	"[C.elegansII] s2622 : mid larval lethal.  NA1. [BC]"	
"let-755"	"III"	-0.9	"[C.elegansII] s2600 : early\/mid larval lethal.  NA1. [BC]"	
"let-758"	"III"	-5.48258	"[C.elegansII] s2607 : sterile adult.  NA1. [BC]"	
"let-759"	"III"	-5.5	"[C.elegansII] s2595 : sterile adult.  NA1. [BC]"	
"let-761"	"III"	-1.70024	"[C.elegansII] s2461 : early larval lethal.  NA1. [BC]"	
"let-764"	"III"	-0.8	"[C.elegansII] s2616 : early larval lethal.  OA1: s2443 (pka let-708, early larval arrest). [BC]"	
"let-765"	"III"	-0.9	"[C.elegansII] s2575 : early larval lethal, L2 arrest with lineage abnormalities\; in males, B.a and B.p equal in size.  s2575\/Dfarrests at L1.  OA1: s2630 (pka let-745, midlarval lethal). [BC]"	
"let-766"	"III"	-0.5	"[C.elegansII] s2463 : early larval lethal. NA1. [BC]"	
"let-767"	"III"	-1.4	"[C.elegansII] s2464 : early larval lethal. NA1.  [BC]"	
"let-768"	"III"	-0.74	"[C.elegansII] s2592 : mid\/late larval lethal.  OA2: s2482 (sterile), s2628 (late larval lethal). [BC]"	
"let-771"	"III"	-0.8	"[C.elegansII] s2442 : sterile adult.  NA1. [BC]"	
"let-774"	"III"	-1.42	"[C.elegansII] s2615 : early larval lethal.  NA1. [BC]"	
"let-778"	"III"	-2.1	"[C.elegansII] s2584 : early larval lethal.  NA1. [BC]"	
"let-782"	"III"	-1.69571	"[C.elegansII] s2591 : variable sterile adult.  NA1. [BC]"	
"let-783"	"III"	-0.8	"[C.elegansII] s2601 : embryonic or early larval lethal.  NA1. [BC]"	
"let-786"	"III"	-0.4	"[C.elegansII] s2631 : early larval lethal.  NA1. [BC]"	
"let-789"	"III"	-2.1	"[C.elegansII] s2606 : sterile adult.  NA1. [BC]"	
"let-852"	"II"	3.53	"[C.elegansII] cc502 : early larval lethal.  OA3: cc503 (mid larval lethal), cc504 (late larval lethal). [PD]"	
"let-853"	"II"	3.48	"[C.elegansII] cc505 : embryonic lethal.  OA2. [PD]"	
"let-854"	"II"	3.49	"[C.elegansII] cc507 : embryonic lethal.  OA1. [PD]"	
"let-855"	"II"	3.5	"[C.elegansII] cc509 : early larval lethal.  OA8. [PD]"	
"let-856"	"II"	3.51	"[C.elegansII] cc514 : mid larval lethal.  OA6. [PD]"	
"let-857"	"II"	3.52	"[C.elegansII] cc516 : embryonic lethal.  OA5. [PD]"	
"let-858"	"II"	3.07	"[C.elegansII] cc500 : embryonic lethal.  OA2. Two strongest alleles arrest at 1.5\/2.5 fold elongation stage, often with head vacuoles\;transgenically rescued animals survive to sterile adult, abnormal germ line. Cloned : partial cosmid rescue (F33A8),to viable sterile adult phenotype.2.8 kb transcript, predicted 90 kD novel protein. [PD]"	
"let-974"	"III"	-0.305761	"[C.elegansII] s230 : late larval lethal.  NA1. [BC\; KR]"	
"let-975"	"III"	-0.305761	"[C.elegansII] s255 : sterile adult.  NA1. [BC\; KR]"	
"let-976"	"III"	-0.305761	"[C.elegansII] s267 : lethal.  NA1. [BC\; KR]"	
"let-977"	"III"	-0.305761	"[C.elegansII] s966 : sterile adult.  NA1. [BC\; KR]"	
"let-978"	"III"	-0.305761	"[C.elegansII] s1050 : sterile adult.  OA1: s377 (similar). [BC\; KR]"	
"let-979"	"III"	0.191137	"[C.elegansII] s231 : lethal.  NA1. [BC\; KR]"	
"let-980"	"III"	0.191137	"[C.elegansII] s424 : mid larval lethal.  NA1. [BC\; KR]"	
"let-981"	"III"	0.191137	"[C.elegansII] s453 : lethal.  OA3: s222, s529 (larval lethal), s1072 (sterile adult). Cloned: cosmid rescue (ZK643)[BC\; KR]"	
"lev-1"	"IV"	8.09006	"[C.elegansII] e211 : (pka tmr-1) almost normal movement in absence of drug uncoordinated but not hypercontracted in 1 mM levamisole. ES2. ME3. OA>10: x22, e289, x577  etc.  Also two rare semidominant alleles with uncoordinated phenotype, x21 (uncoordinated Egl-c, ME3), x63. Cloned: corresponds to acr-1, encoding subunit of nicotinic acetylcholine receptor. [Lewis et al. 1980, 1987\; ZZ\; MQ]"	
"lev-8"	"X"	5.1432	"[C.elegansII] x15 : almost normal movement in absence of drug, weakly resistant to 1 mM levamisole\; body contracts but head does not\; more resistant at 25C. ES2. NA1. [Lewis et al. 1980, 1987\; ZZ]"	
"lev-9"	"X"	-2.30766	"[C.elegansII] x16 : almost normal movement in absence of drug, weakly resistant to 1 mM levamisole. ES2. OA2. [Lewis et al. 1980, 1987\; ZZ]"	
"lev-10"	"I"	23.9124	"[C.elegansII] x17 : almost normal movement in absence of drug, weakly resistant to 1 mM levamisole. ES2. NA1. [Lewis et al. 1980, 1987\; ZZ]"	
"lev-11"	"I"	25.4655	"[C.elegansII] x12 : slightly long, uncoordinated, mild twitcher phenotype\; grows well in 1 mM levamisole\; strong semi-dominant suppressor of unc-90(e1463). ES3 ME2. OA6: x1 (twitcher), e1724 (lethal). Also Pat (paralysed arrest at two-fold) alleles: st536 (severe paralysis),st577, st566 (some pharyngeal pumping. Greatly reduced staining for tropomyosin, probably corresponds to structural gene tmy-1. [Lewis et al. 1980\; Williams and Waterston 1994\; HK\; ZZ]lfeLet-23 FErtility effector\/regulator.PS."	
"lin-1"	"IV"	-8.47126	"[C.elegansII] e1777amb : adult hermaphrodite has multiple (one to four) vulval protrusions, often bursts at abnormal vulva during L4 molt\; ES3 (adult)\/ ES1 (larvae)\; HME2\; adult male has rudimentary ectopic hooks ES1 ME0. OA>20: e1026, n431amb (phenotype resembles e1777), e1275 (weaker, slightly ts phenotype\; ME1), n746, n1141 etc. Cloned: encodes predicted protein with strong similarity to ETS family transcription factors. [Ferguson et al. 1985\; Katz et al. 1995\; GS\; MT]"	
"lin-2"	"X"	7.27956	"[C.elegansII] e1309 : adult hermaphrodite vulvaless (penetrance 93\%)\; ES2 (adult)\/ ES1 (larvae)\; HME2\; adult male wildtype ME3. NA13: e1453amb (non-null, lower penetrance than e1309, 50\% vulvaless), n105ts (penetrance 24\% at 15C, 90\% at 25C) n768 (weak allele multiple vulval protrusions penetrance 21\%), n397 (deletes most of gene), etc. Cloned: encodes predicted protein with PDZ domain,similarity to guanylate kinase, Drosophila discs large.  Mutants delocalize LET-23. [Ferguson et al. 1985\; SD\; MT]"	
"lin-3"	"IV"	4.82283	"[C.elegansII] e1417 : adult hermaphrodite vulvaless (penetrance 89\%)\; HME2\; adult male wildtype ME2. OA>10: n378 (resembles e1417)d,\; n1059 (early larval lethal), n1058 (early larval lethal\/sterile adult),s751 (pka let-94, late larval lethal, s751\/Df early larval lethal), s1750 (homozygote and hemizygote mid larval lethal), etc. Cloned: encodes proteins with similarity to EGF family. Transgene overexpression leads to Muv(extra vulval differentiation). [Hill and Sternberg 1992\; BC\; MT\; PS]"	
"lin-4"	"II"	-0.900514	"[C.elegansII] e912pdi : heterochronic, retarded adult hermaphrodites long abnormal movement vulvaless lack adult cuticle ES3 (adult) ES1 (larvae)\; HME0 (20C)\/HME1 (15C) adult males lack copulatory structures ME0. OA1: ma161 (resembles e912). Cloned: encodes two small RNAs with nocoding potential. [Lee et al. 1993\; Wightman et al. 1993\; GR\; VT]"	
"lin-5"	"II"	0.56696	"[C.elegansII] e1348 : thin, sterile and uncoordinated after L1\; all postembryonic divisions fail from defective cytokinesis although DNA replication continues. No sexual maturation in either sex. ES3 ME0. OA1: e1457 (similar phenotypes). Cloned: cosmid rescue (C03G3)[Sulston and Horvitz 1981\; Albertson et al. 1978\; MT]"	
"lin-6"	"I"	-9.22594	"[C.elegansII] e1466 : thin, sterile and uncoordinated after L1\; most postembryonic divisions absent or defective from absence of DNA synthesis\; Q and I divisions normal. No sexual maturation in either sex. ES3 ME0. OA1 (pka let-358). [Sulston and Horvitz 1981\; MT]"	
"lin-7"	"II"	22.9279	"[C.elegansII] e1413amb : adult hermaphrodite vulvaless (penetrance 98\%) HME2\; adult male wildtype ME3. OA>10: e974amb, n308 (both resemble e1413), n308cs (penetrance 95\% at 15C 28\% at 25C), n385, n764 etc. Cloned: encodes predicted 33kD protein withPDZ domain, similarity to junction-associated proteins.  Mutants delocalize LET-23. [Sulston and Horvitz 1981\; MT\; SD]"	
"lin-8"	"II"	-8.40199	"[C.elegansII] n111 : adult hermaphrodite wildtype,  Muv in homozygotes with lin-9, lin-35, lin-36 or lin-37\; male wildtype ME3.  Mosaic analysis indicates action is cell nonautonomous. OA1: n762. [Ferguson and Horvitz 1989\; Hedgecock and Herman 1995\; MT]"	
"lin-9"	"III"	-0.003911	"[C.elegansII] n112 : adult hermaphrodite wildtype Muv in homozygotes with lin-8 or lin-38. OA2: n942, n943 (both sterile non-Muv alone\; sterile Muv with lin-8 etc.). Cloned: encodes predicted 642 aa novel protein, hydrophobic, possible C-term transmembrane domains. [Ferguson and Horvitz 1989\; MT]"	
"lin-10"	"I"	2.53584	"[C.elegansII] e1439 : adult hermaphrodite vulvaless (penetrance 95\%) HME2\; adult male wildtype ME3. Similar phenotype in e1439\/Df. OA>5\; e1438,  n299, n1299, n1329, n1638amb, etc.C loned: encodes predicted 407aa novel protein\;antibody staining indicates ubiquitous,cytoplasmic. [Kim and Horvitz 1990\; MT\; SD]"	
"lin-11"	"I"	4.83733	"[C.elegansII] n389 : adult hermaphrodite vulvaless (penetrance 100\%)\; 2ary lineages become symmetrical\;HME0\;  slightly uncoordinated\; adult male slightly uncoordinated\; wildtype morphology ME1. OA3: n382 (resembles n389), n672sd (n672\/+ is 5\% Vul), n566 (weaker allele HME2)). Cloned: encodes LIM class homeoprotein. lin-11:lacZ expressed in some VPC 2ary descendants, some gonadal cells, VC neurons, some head neurons. [Freyd et al. 1990\; MT]"	
"lin-12"	"III"	0.124522	"[C.elegansII] n941 : abnormal vulva, sterile small, many lineage transformations. ES3 ME0. Also gain-of-function alleles:  n137sd : adult hermaphrodite Muv, many lineage transformations. ES3 ME1 (n137\/+ ME3). OA>15(gf): n177 (resembles n137)\; n676, n302, n379 (these alleles have semidominant Vul phenotype, probably less hypermorphic)). Also intragenic revertants of dominant alleles OA>50 (ird): most have lf phenotype e.g. n137n720, n676n909amb (resemble n941), n137n460ts (wildtype at 25C, Muv at 15C)\; many other non-null alleles with tissue-specific effects, also Tcl-insertion null alleles.See also sel, lag, glp-1\; Lag functions redundant with glp-1. Cloned: encodes 1429 aa protein, transmembrane receptor related to GLP-1, Drosophila Notch\; 13 EGF-like repeats and other repeatsin extracellular domain, 6 ANK repeats in intracellular domain.  Very extensive developmental and molecular analysis, many mutations sequenced. [Greenwald et al. 1983\; Wilkinson et al. 1994\; Wilkinson and Greenwald 1995\; GS]"	
"lin-13"	"III"	-0.613837	"[C.elegansII] n387ts,mat : adult hermaphrodite Muv and sterile at 25C, maternally rescued at 15C (n387 progeny of n387\/+ are wildtype but produce sterile F2 only). Males have occasional ventral protrusions ME0. n387\/Df at 25C is early larval lethal. OA1: n388 (similar). Cloned: cosmid rescue (K04F4)[Ferguson and Horvitz 1985, 1989\; GS\; MT]"	
"lin-14"	"X"	3.38891	"[C.elegansII] n526n540ird : lf allele (Class II, a-b-), precocious heterochronic lineage alterations in ectoderm\; abnormal development of vulva,endoderm and mesoderm\; abnormal cuticle formation\; precocious dauer entry at L1 molt\; ES2\; male more severely affected, only three molts, gonadal development abnormal. Similar phenotype in n536n540\/Df. OA>10: n179ts, etc.\; also n355n679ird,ts (Class V, a-b+, only early events precocious)\; n360ts(Class III, a+b-, only late events precocious). Also gain-of-function alleles:  n536sd (Class I, retarded heterochronic alterations in many lineages\; abnormal vulval development, cuticle formation, supernumerary molts, extra divisions in sex mesoblasts, intestine etc.\; gonadal lineages normal. ES3), n355sd(similar).  Numerous intragenic revertants. For both lf and gf mutations, late lineages are less affected if animal develops via dauer stage. Cloned: two 3.5 kb transcripts, differing 5',encoding 70 kD novel proteins\; antibodies stain nuclei\; protein levels high in L1, reduced or absent later.  Gain-of-function mutations affect3' UTR. [Ruvkun and Giusto 1989\; Wightman et al. 1993\; GR\; VT]"	
"lin-15"	"X"	22.2964	"[C.elegansII] n309 : adult hermaphrodite Muv, vulva either normal or nonfunctional, two to six ventral protrusions. Some animals rupture during L4 molt. Adult males have one to three ventral protrusions, rudimentary ectopic hook. ME0. Possibly enhanced phenotype in n309\/Df. OA>10: e1763, n765ts (wildtype at 15C, Muv at 25C, maternal effect Muv at 20C)\; n767 (class A allele, wildtype alone, Muv in homozygotes with lin-9,35,36,37), n744 (class B allele, wildtype alone, Muv with lin-8,38),  etc. Cloned: locus encodes two collinear transcripts,B (5') and A (3', SL2 transpliced)\; encode predicted 1440 aa and 719 aa novel proteins. [Clark et al.1994\; Huang et al. 1994\; MT\; PS]"	
"lin-16"	"III"	-0.817901	"[C.elegansII] e1743 : thin, sterile, uncoordinated after L1\;  extensive failure of postembryonic divisions\; no polyploid cells\; most Vn.p cells join syncytium. [TU]"	
"lin-17"	"I"	-7.43999	"[C.elegansII] n671 : adult hermaphrodite slightly uncoordinated, long, irregularly shaped tail, vulva may be nonfunctional\; many hermaphrodites (50\%) have single small protrusion posterior to vulvas\; some gonadal abnormality and sterility. Abnormally long excretory canals.  Diverse asymmetric cell divisions are symmetric or reversed. ES2. Male tail grossly abnormal, may rupture during L2 molt ME0. OA4: n677 (resembles n671), n669 (less penetrant for Muv phenotype), e2257, etc. Cloned: encodes predicted membrane protein(seven TM domains), 28\% identity to Drosophila frizzled. [Sternberg and Horvitz 1988\; Herman et al. 1995\; MT]"	
"lin-18"	"X"	-8.16697	"[C.elegansII] e620 : some (<50\%) hermaphrodites have single small protrusion posterior to vulva, occasional vulval rupture\; Polarity of 2ary lineages variably disrupted. slight maternal effect\; slightly ts. e620\/Df stronger phenotype. ES2. Males phenotypically wildtype ME3. OA1: n1051amb,ts (resembles e620). [Ferguson et al. 198\; MT\; PS]"	
"lin-23"	"II"	-0.396977	"[C.elegansII] e1883 : extra cell divisions in all postembryonic lineages, apparently stochastic.  Sterile, eggs undergo many cell divisions, no morphogenesis. ES3 (adult) ME0. OA3: e1924,  e1925, e1521 (pka stu-1, thin, sterile,loopy uncoordinated). Cloned: predicted protein has similarity to yeast CDC4. [Miller et al. 1993\; NJ]"	
"lin-24"	"IV"	5.70678	"[C.elegansII] n432sd : adult hermaphrodite vulvaless (n432 95\% Egl, n432\/+ 55\% Egl). Pn.p cells degenerate, dependent on ced-2,-5,-10.ES2. Male WT, ME3. Probably neomorphic, n432\/nDf27 is 54\% Egl,  +\/nDf27 is wildtype. OA1: n1057amb (non-null, n1057 and n1057\/Df are wildtype, n1057\/+ is 33\% Egl)). Null phenotype probably WT. [Ferguson et al. 1987\; Ellis et al. 1991\; MT]"	
"lin-25"	"V"	4.50576	"[C.elegansII] e1446 : adult hermaphrodite vulvaless,11\% sterile. VPC all 3ary except P6.p. Suppresses lin-1, let-60(gf), not lin-12(gf).ES2. HME1. Males morphologically wildtype ME0. OA9: n545ts (at 25C resembles e1446, at 15C 8\% Vul), n1063, ku78,  ar90 (probable null, resembles e1446), etc. Cloned: encodes predicted 1139 aa novel protein. [Tuck and Greenwald 1995\; GS]"	
"lin-26"	"II"	0.484136	"[C.elegansII] n156 : adult hermaphrodites vulvaless ( >99\%), slightly small and fat\; HME1. General hypodermal and support cell defects,hypodermal cells die or neuralize. 2\% sterile.ES2. Males very small scrawny rounded tail\; ME0. n156\/Df is larval lethal. OA4: mc1, mc2 (both embryonic lethal),pk38tci, mc15 (deletion derivative). Cloned: encodes predicted zinc finger transcription factor.  Antibody stains hypodermis,support cells, uterine cells. [Labouesse et al. 1994\; MT\; ML]"	
"lin-28"	"I"	2.73242	"[C.elegansII] n719 : precocious heterochronic alterations in many ectodermal lineages, more severe than lin-14(null)\; precocious abnormal vulva development\; Egl\; abnormal cuticle formation\; only three molts\; hermaphrodite and male V5.pa make ray cells in L2\; gonadal development normal. Late lineages less affected if animal develops via dauer stage. ES3 ME0. OA3: n947, n1119, n1120 (all resemble n719). Cloned: 1.5 and 1.6 kb transcripts, encode predicted Y-box protein. [Liu and Ambros 1991\; Arasu et al. 1992\; GR\; VT]"	
"lin-29"	"II"	4.25769	"[C.elegansII] n333 : retarded heterochronic alterations in L4 seam cells\; no adult alae formed\; supernumerary divisions\; also Egl, Evl\;phenotype not affected by development via dauer stage. ES3.  ME0 (males have short spicules).OA3: n546 (smg suppressible), n1440, n836, ga94 (adult cuticle but abnormal vulva). Cloned: 1.8 and 2.4 kb transcripts (different 5'),present throughout larval development, maximal L4\; 2.4 kb encodes 50 kD protein with five zinc fingers.  Antibody shows LIN-29 stage specific expression in nuclei of seam cells, hyp-7 of L4, some vulval nuclei also. [Rougvie and Ambros 1995\; VT\; GR]"	
"lin-31"	"II"	-5.27281	"[C.elegansII] n301 : adult hermaphrodite Muv, vulva either functional or nonfunctional protrusion\; 0-4 small ventral protrusions. VPC cells adopt 1ary\/2ary\/3ary fate at random.ES3 (adult). Male gross morphology wildtype ME0. Similar phenotype in n301\/Df. Mosaic analysis indicates cell-autonomous action.OA>10: e1750, e2181, n376, n428, n1301 etc. Cloned: 1.5 transcript, expressed throughout development, encodes predicted 237 aa protein with similarity to fork head\/HNF-3 transcription factors.  lin-31:GFP expressed in P3.p - P8.p. [Miller et al. 1993\; SD]"	
"lin-32"	"X"	-15.1167	"[C.elegansII] e1926 : many neuroblasts adopt hypodermal fates (Q, postdeirid, ray neuroblasts make only seam or syncytial nuclei)\; Q\/V5 embryonic division delayed\; various embryonic sensory neurons absent or displaced. Loopy foraging.  Anterior rays most affected.  Mutant phenotypes more severe in e1926\/Df. ES1 (hermaphrodite) ES3 (adult male). OA2: u282 (stronger, 90\% of males lack rays\; also lack PLM, AVM, PVM neurons, hence touch-insensitive in tail), bx46 (intermediate phenotype). Cloned: encodes predicted bHLH transcription factor,66\% identity to Drosophila atonal.  Transgene overexpression leads to ectopic ray papillae. [Zhao and Emmons 1995\; EM\; KP]"	
"lin-33"	"IV"	2.58759	"[C.elegansII] n1043sd : adult hermaphrodite vulvaless (n1043 95\% Egl n1043\/+ 77\% Egl). Pn.p cells undergo cell death (ced-2,5,10 dependent). ES2. Male gross morphology wildtype ME3. OA1: n1044 (similar).  Null phenotype uncertain. [Ferguson et al. 1987\; Ellis et al. 1991\; MT]"	
"lin-35"	"I"	0.31	"[C.elegansII] n745 : almost WT alone (reduced fertility)\; Muv (extra vulval differentiation) in homozygotes with lin-8, lin-38 or lin-15(n767). ES2. OA1: n373 (similar). [Ferguson and Horvitz 1989\; MT\; PS]"	
"lin-36"	"III"	-0.432203	"[C.elegansII] n766 : wildtype alone,  Muv in homozygotes with lin-8, lin-38 or lin-15(n767). Mosaic analysis indicates autonomous action in VPC.  ES2. ME3. OA3: n772 (similar), n750 etc. Cloned: encodes predicted 926 aa novel protein. [Ferguson and Horvitz 1989\; MT\; PS]"	
"lin-37"	"III"	-0.780716	"[C.elegansII] n758 : wildtype alone Muv in homozygotes with lin-8 lin-38 or lin-15(n767). ES2.  NA1. [Ferguson and Horvitz 1989\; MT\; PS]"	
"lin-38"	"II"	12.6162	"[C.elegansII] n751 : almost WT alone (reduced fertility),Muv in homozygotes with lin-9 lin-35 lin- 36 lin-37 or lin-15(n744). Non-cell autonomous ? ES2. OA1: n761 (similar). [Ferguson and Horvitz 1989\; MT\; PS]"	
"lin-39"	"III"	-0.654782	"[C.elegansII] n709ts : some or all P3.aap - P8.aap (presumptive VC neurons) die in hermaphrodites (ES1)\; variably Egl (ES2)\; variably abnormal vulval divisions. Multiple defects in specification of fates in mid-body.  ME3. OA1: n1490, mu26. Cloned: encodes homeoprotein (pka ceh-15) relatedto Drosophila Dfd\/Scr.  lin-39:lacZ expressed in central body region of egg, larva, adult. [Clark et al. 1993\; Wang et al. 1993\; CF\; MT]"	
"lin-40"	"V"	-8.40252	"[C.elegansII] e2173 : sterile Evl adult, multiple defects\; males very abnormal.  ES3.  ME0.  OA>15: s1053 (pka let-432), s1345mut, s1351mut, s1669fdi, s1675fdi, s1704, s1916uvi, etc. Homozygous developmental arrest stages range from early\/mid larval lethal to Mel (early larval lethal)\; sterile and Mel adults are Evl\;complex complementation, at least 5 classes\; high mutation frequency.  Also dominant effects on sperm number (dominant increase in Df\/+, decrease in some alleles). [Johnsen and Baillie 1991\; BC]"	
"lin-41"	"I"	4.89	"[C.elegansII] ma104 : heterochronic defect in L4\/A switch. [VT]"	
"lin-42"	"II"	-12.7696	"[C.elegansII] n1089 : precocious HSN differentiation\; heterochronicdefect in L4\/A switch. [MT\; VT]"	
"lin-44"	"I"	-1.61405	"[C.elegansII] n1792 : polarities of B, F, U, T divisions reversed. n1792\/Df similar.  Mosaic analysis indicates non-autonomous action.  OA1: n2111 (similar). Cloned: encodes member of Wnt family.  lin-44:lacZ and lin-44:GFP expressed in tail tip hypodermis. [Herman et al. 1995\; EH\; MT\; SP]"	
"lin-45"	"IV"	3.27767	"[C.elegansII] sy96 : subviable, >90\% die as rod-like L1, escapers mostly Egl, Vul\; suppresses lin-15Muv\; impenetrant P12 to P11 transformation\; partial maternal rescue of larval lethality. Effects on male development resemble F and U ablation.  OA1: n2018cs (most animals vulvaless or inviable at 15C\; 25\% non-Vul at 25C). Cloned: pka raf-1, encodes 813 aa predicted protein with extensive similarity to raf kinases. Dominant negative transgene frequently Vul. [Han et al. 1993\; MH\; MT\; PS]"	
"lin-46"	"V"	4.77	"[C.elegansII] Mutation suppresses Lin-28\; some lateral hypodermal cells divide at 4th molt rather than form alae.  Enhanced by starvation. [VT]"	
"lin-47"	"X"	2.19618	"[C.elegansII] sy32: males have abnormal spicules. B cell lineage defect, possibly additional defects. [PS]"	
"lin-48"	"III"	-4	"[C.elegansII] sy234 : males have abnormal spicules.  Lineagedefects in B, F, U. [PS]"	
"lin-49"	"IV"	3.97343	"[C.elegansII] sy238 : males have short crumpled spicules, defects in F and U lineages. Both males and hermaphrodites are sickly and have some 'scarring' at the rectum. sy238)\/Df animals arrest at mid-larval stage, heavy scarring at int\/rect junction. Males have B lineage defect.  OA1: s1198 (stronger,mid larval lethal). [PS, BC]"	
"lon-1"	"III"	-1.70042	"[C.elegansII] e185 : about 50\% longer than wildtype at all stages, markedly tapering tail and head\; low penetrance tendency to form constriction behind head, may result in auto-decapitation. Eggs elongated.ES3. Male bursa elongated ME0. OA5: e43, e1820, n1130 etc. (some have stronger Lon phenotype than e185, all show some decapitation). [Brenner 1974\; MT]"	
"lon-2"	"X"	-6.32469	"[C.elegansII] e678 : about 50\% longer than wildtype at all stages\; some embryonic lethality\; ES3. Male bursa slightly elongated, ME3 (ME0 at25C?). OA4: e405, e434, n1346, n1630 etc. (allsimilar to e678). [Brenner 1974]"	
"lon-3"	"V"	4.24819	"[C.elegansII] e2175mut : adult about 50\% longer than WT.ES3 (adult), ME1. NA1. [CB\; KE]"	
"mab-2"	"I"	0.360573	"[C.elegansII] e1241 : adult male has 6-18 missing copulatory rays as a result of variable failures of V and T lineages\; bursa often grossly distorted. ME0\/ME1. Hermaphrodite gross phenotype normal\; late hypodermal V and T divisions variably defective. ES1 (hermaphrodite) ES3 (adult male).  NA1. [Hodgkin 1983a\; Link et al. 1988\; CB]"	
"mab-3"	"II"	1.68852	"[C.elegansII] e1240 : adult male tail morphology grossly abnormal, often with hermaphrodite tail spike\; adult male synthesizes yolk proteins\; V lineages abnormal, other defects. ES3 (adult male), ME0. Hermaphrodite WT.OA4: e1921ts, e2093 (similar but slightly weaker phenotypes than e1240), e2093, e2212. [Shen and Hodgkin 1988\; CB]"	
"mab-4"	"III"	8.25588	"[C.elegansII] e1252 : adult male has swollen bursa ES3 ME1. Adult hermaphrodite has protruding vulva. ES2. NA1. [Hodgkin 1983a\; Link et al. 1988\; CB]"	
"mab-5"	"III"	-0.564049	"[C.elegansII] e1239 : postembryonic lineages and migrations in pre-anal region generally abnormal\; adult male tail morphology thin, grossly abnormal\; V rays missing, T rays present\; sex mesoblast lineages etc. abnormal. ES3 (male) ME0. Hermaphrodite gross phenotype WT but V divisions, Q migrations coelomocytes all abnormal. ES1 (hermaphrodite).  Mosaic analysis indicates cell autonomous.  Similar mutant phenotypes in e1239\/Df. OA>8: e1936, e2011 (Q24och), e2088 (all resemble e1239) etc. Also bx54sd (dominant missense, ray fusion phenotype) See also lin-21. Cloned: HOM-C member, encodes homeoprotein related to Antennapedia.  Extensive molecular analysis. [Kenyon 1986\; Cowing and Kenyon 1992\; CF]"	
"mab-6"	"II"	-0.935052	"[C.elegansII] e1249 : adult male has very swollen bursa ES2 ME1. Hermaphrodite WT. NA1. [Hodgkin 1983a\; Link et al. 1988\; CB]"	
"mab-7"	"X"	-19.2336	"[C.elegansII] e1599 : adult male slightly small, all bursal rays swollen\; bursal fan reduced. ES2 ME1. Hermaphrodite slightly dumpy. ES2. OA1: e2150. [Hodgkin 1983a\; Link et al. 1988\; CB]"	
"mab-8"	"II"	-1.19451	"[C.elegansII] e1250 : adult male has swollen bursa. Adult hermaphrodite has protruding vulva. ES2 ME1. NA1. [Hodgkin 1983a\; Link et al. 1988\; CB]"	
"mab-9"	"II"	-14.4772	"[C.elegansII] e1245amb : male tail morphology and development grossly abnormal, B lineage defective, resembles Y lineage\; also probable F to U lineage transformation\; many males die or rupture during L4 molt.  e1245\/Df similar. ES3 (male), ME0. Hermaphrodite grossly WT, sometimes constipated as a result of rectal abnormalities.rectal cells. OA2: e2410, e2376 (weaker allele). [Chisholm and Hodgkin 1989]"	
"mab-10"	"II"	3.04651	"[C.elegansII] e1248 : adult male has slightly swollen bursa, reduced fan, thin rays\; some adult males have supernumerary molt, second adult cuticle.  e1248\/Df more severe. ES2 ME0. Hermaphrodite has slightly protruding vulva. ES2. NA1. [Hodgkin 1983a\; Link et al. 1988\; CB\; CL]"	
"mab-12"	"IV"	-15.3271	"[C.elegansII] e2166 : adult male has swollen bursa. Adult hermaphrodite has protruding vulva. ES2, ME1. [Hodgkin et al. 1989]"	
"mab-18"	"X"	1.97535	"[C.elegansII] bx23 :  ray 6 to ray 4 transformation, resulting in fused double ray 4. OA1: bx79. Cloned: mab-18 activity provided by shorter transcripts from vab-3, encoding only homeodomain. mab-18:GFP expressed in ray 6 sublineage from L4 onward. [Zhang & Emmons 1995\; CZ\; EM]"	
"mab-19"	"X"	-2.79012	"[C.elegansII] bx38 : variable loss of T rays (lineage defect), some retention of tail spike, gonad morphology defects.  Hermaphrodite brood size reduced to 100. Partly suppressed by many dpy mutations, or stress\; synthetic lethal with many unc-17 alleles.  bx38\/Df is lethal.  OA1: bx83 (similar). [Sutherlin and Emmons 1994\; EM]"	
"mab-20"	"I"	-10.479	"[C.elegansII] bx24 : displacements and fusions in rays 1,2,3,4,8,9\;  R1,2,4 probably transformed to R3. Variable bulges in posterior body region.  OA1: bx61ts (weaker). [Baird et al. 1991\; Chow and Emmons 1994\; EM]"	
"mab-21"	"III"	-3.30695	"[C.elegansII] bx53 : transformation of thick ray 6 to a thin ray, which is anteriorly displaced and fuses with ray 4 (>95\%). Tenth ray derived from T.apapa, between rays 5 and 7, is found in ~50\% of sides scored.  Both males and hermaphrodites have slightly shorter body length (~85\% of wild type)\; reduced brood size\; males backward Unc, reduced mating efficiency. Mosaic focus cell autonomous for R6, non-autonomous for T.apapa.  Probable hypomorph, bx53\/Df is embryonic lethal.  OA2: bx41, sy155 (similar). Cloned: encodes predicted 386 aa novel protein. [Baird et al. 1991\; Chow et al. 1995\; KC\; EM\; PS]"	
"mab-23"	"V"	2.48087	"[C.elegansII] e2518spo : no phenotype in hermaphrodite, male tail very swollen, rays indistinct.  ME0.  Vancouver wild isolate KR314 is naturally homozygous for e2518. [CB]"	
"mab-26"	"IV"	-29.2	"[C.elegansII] bx80sd : fusions among all rays\; also head, body and (especially) tail deformities\; bx80\/+ impenetrant R4 to R3 transformation. [Chow and Emmons 1994\; EM]"	
"mab-27"	"X"	16.4415	"[C.elegansII] sy202 : males have abnormal spicules. Both males and hermaphrodites exhibit a slight 'loopy' Unc. Possibly also very weakly penetrant lineage defect. NA1. [PS]"	
"mad-1"	"I"	26.8026	"[C.elegansII] qm39 : hatchlings short and deformed, resembleDpy-17\; at later stages variable, anterior body short, posterior half thin\;  high larval lethality\; full zygotic rescue, almost complete maternal rescue. NA1. [MQ]"	
"mad-2"	"I"	5.55847	"[C.elegansII] qm62 : adults short, lethargic but hyperactive for foraging movement, very rapid pumping after touch\; tails abnormal in both sexes\; very slow development\; high larval lethality\; full zygotic and maternal rescue.  OA1 (qm58). [MQ]"	
"mad-3"	"V"	5.53331	"[C.elegansII] qm64 : hatchlings of variable length, shortest die\; adults short, unhealthy\; high embryonic and larval lethality\; full zygotic and maternalrescue.  NA1. [MQ]"	
"mah-2"	"X"	-2.1	"[C.elegansII] cn110ts,sd : rigid paralysis on shift to 30C,reversible on shift-down.  NA1. [Hosono et al. 1985]"	
"mal-1"	"IV"	9.56754	"[C.elegansII] qm27 : variable, dorsal protrusions on head and tail, head frequently twisted\; high embryonic and larval lethality\; full zygotic and maternal rescue.NA1. [MQ]"	
"mal-2"	"V"	21.2281	"[C.elegansII] qm31 : variably deformed\; frequently hypertrophic ventral side of head\; high embryonic and larval lethality\; no zygotic rescue, full maternal rescue.OA2 (qm16, qm35). [MQ]"	
"mal-3"	"I"	0.820936	"[C.elegansII] qm34 : head frequently deformed because buccal opening displaced ventrally, dorsally or laterally\; some embryonic lethality, very high larval lethality\; full zygotic and maternal rescue. NA1. [MQ]"	
"mal-4"	"II"	0.783831	"[C.elegansII] qm36 : hypertrophic left side of the head, usually anterior to terminal bulb of pharynx\; high larval lethality\;  full zygotic and maternal rescue.  NA1. [MQ]"	
"mau-1"	"V"	-20.9774	"[C.elegansII] e2507 : variable Unc: kinking, coiling or paralysis\; Egl\; neuroanatomical defects\; some lethality\; full zygotic and maternal rescue.  OA1 (qm6). [MQ]"	
"mau-2"	"I"	2.49838	"[C.elegansII] qm4 : kinky Unc, Egl, neuroanatomical defects\; short excretory canals\; Egl\; some lethality\; full zygotic rescue, almost complete maternal rescue, no maternal rescue of Egl.  OA2 (qm5, qm40). [MQ]"	
"mau-3"	"IV"	3.51788	"[C.elegansII] qm10 : Unc, progressive paralysis, abnormal muscle anatomy\; full zygotic and maternal rescue.NA1. [MQ]"	
"mau-4"	"X"	24	"[C.elegansII] qm45 : Unc, stiff posterior body, withered tail\; some lethargy\; full zygotic rescue, almost complete maternal rescue.  OA2 (qm18, qm19 : both[MQ]ts alleles, WT at  15C, mutant 20C, lethal 25C). [MQ]"	
"mau-5"	"III"	-16.6633	"[C.elegansII] qm17 : progressive sluggishness and jerky forward movement\; Egl\; abnormal muscle anatomy\;full maternal and zygotic rescue.  NA1. [MQ]"	
"mau-6"	"V"	2.80761	"[C.elegansII] qm50 : progressive paralysis, full paralysis and rapid death after 4th molt\; some larval lethality.  Complete zygotic rescue, almost complete maternal rescue.  NA1. [MQ]"	
"mau-7"	"IV"	-28	"[C.elegansII] qm56 : Unc, lethargic, kinky jerky ratchet-like movements in reverse\; constipated (Exp)\; some lethality\;  full zygotic and maternal rescue.NA1. [MQ]"	
"mau-8"	"IV"	3.42604	"[C.elegansII] qm57 : Unc, lethargic, kinky jerky ratchet-like movements in reverse\; constipated (Exp)\; some lethality\;  full zygotic and maternal rescue.NA1. [MQ]"	
"mec-1"	"V"	0.338776	"[C.elegansII] e1066 : (pka che-4) touch insensitive\; lethargic\; microtubule cells lack extracellular mantle often displaced\; some amphidial neurons also displaced, defective fasciculation. ES2 ME2. OA>50: e1292, e1336, u39amb etc. Most alleles resemble e1066 but may lack amphidial neuron displacement. [Perkins et al. 1986]"	
"mec-2"	"X"	-4.58483	"[C.elegansII] u8amb : touch insensitive\; lethargic. ES2. ME?.  OA>50: e75 (recessive, ME3), u7cs, e1084 (probable null), e1514, e1608dm, u284sd, etc.  Alleles vary in phenotype from weak recessive to strong dominant Mec\; complex complementation. Cloned: encodes predicted 440 aa protein with central similarity to human stomatin (65\% identity over 247 aa).  mec-2:lacZ expressed in cell bodies and processes of touch cells, some other neurons.??? [Chalfie and Au 1989\; Huang et al. 1995\; TU]"	
"mec-3"	"IV"	4.62987	"[C.elegansII] e1338 : touch insensitive, lethargic\; microtubule cells small and lacking processes, ALM and PLM cells displaced. ES2 ME2. OA>10: e1498, e1612, u467amb,  etc. Also revertant allele e1498u124 (ALM and PLM processes abnormally long). Cloned: encodes LIM class homeoprotein,expressed in touch receptors, FLP, PVD\;extensive molecular analysis. [Way and Chalfie 1989\; Xue et al. 1993\; JW\; TU]"	
"mec-4"	"X"	24.0788	"[C.elegansII] u52amb : touch insensitive, lethargic. ES2 ME2. OA>50: e1339 (weak allele, sometimes touch sensitive in tail), e1497, u45ts etc. Also dominant Deg alleles: e1611dm (pka mec-13, touch insensitive, microtubule cells become vacuolated and die in e1611 and e1611\/+\; neomorphic. ES2 ME3. Intragenic revertants (e.g. e1611e1879) resemble u52. OA2 (dominant). Cloned: encodes protein related to mammalian ENaC sodium channel subunit. Deg alleles are bulky missense changes at A442.  See also deg-1,mec-10. [Driscoll and Chalfie 1991\; Hong and Driscoll 1994\; TU\; ZB]"	
"mec-5"	"X"	22.4098	"[C.elegansII] e1340 : touch insensitive, lethargic\; mantle of microtubule cells not stained by peanut lectin. ES2 ME3. OA>30: e1503ts, e1504, e1790  etc. (many are ts). Cloned: encodes 329 aa collagen. [Chalfie and Au 1989\; Huang and Chalfie 1994\; TU]"	
"mec-6"	"I"	1.46731	"[C.elegansII] e1342 : touch insensitive, lethargic. Suppresses Deg phenotype of mec-4(dm),deg-1(dm), deg-2(dm).ES2 ME3. OA>10: e1609spo,  u247ts (may be Mec only in head), e1472, u450,  etc. [Chalfie and Au 1989\; Huang and Chalfie 1994\; MP\; TU\; ZB]"	
"mec-7"	"X"	-1.31407	"[C.elegansII] e1343sd,ts : touch insensitive, lethargic at 25C\; microtubule cells lack 15-protofilament microtubules\; e1343\/+ variably touch insensitive at 25C\; wildtype at 15C. ES2 ME3. OA>30:n434dm (dominant at all temperatures), e1506 (recessive at all temperatures), e1527,u278 (missense, causes ectopic touch cell branching),u443 (deletion null), etc. Most alleles incompletely dominant and ts. Cloned: encodes beta-tubulin. Antibody stains strongly in touch cells, weakly in some others (FLP, PVD).  45 alleles sequenced. [Savage et al. 1989\; Hamelin et al. 1992\; NW\; TU]"	
"mec-8"	"I"	3.69942	"[C.elegansII] e398amb : touch insensitive lethargic\; disrupted fasciculation of amphid and phasmid channelcilia\; Dyf.  Synthetic lethal with some unc-52(e444)\; Pat.  ES2 ME2. NA16:mn364 (recessive lethal, Pat), mn412 (Mel, Gro). u74, u456, rh170, mn472, u391.  See also smu. Cloned: encodes protein with two copies of RNP predicted RNA binding domain. [Perkins et al. 1986\; Lundquist and Herman 1994\; SP\; NJ\; EH\; TU]"	
"mec-9"	"V"	2.19887	"[C.elegansII] u27amb : touch insensitive lethargic. ES2 ME2. OA>30: e1494, e1852, u164amb etc. Cloned: 2 kb and 3 kb transcripts, transpliced to SL1 and SL2, encode protein with Kunitztype serine protease inhibitor domains, EGF-like repeats.  mec-9:GFP expressed in touch cells and PVD (3kb promoter) or more extensively (2kb promoter). [Chalfie and Au 1989\; Huang and Chalfie 1994\; TU]"	
"mec-10"	"X"	-0.555292	"[C.elegansII] e1515 : touch insensitive lethargic. ES2 ME3. OA5: e1715, etc. [Huang M] TU#66 is a plasmid contained in cosmids F16F9 and K11G11 e1515, e1715. Cloned: encodes 724 aa degenerin protein,related to MEC-4, DEG-1, vertebrate ENaC sodium channel components. [Huang and Chalfie 1994\; MP\; TU\; ZB]"	
"mec-12"	"III"	-9.92098	"[C.elegansII] e1605 : touch insensitive lethargic. ES2 ME3. NA15: e1607 (weaker allele), u94sd (u94\/+ touch insensitive in head only), u241sd,  etc.  Weak alleles often lack synaptic branch of AVM\; strong alleles have few microtubules in microbule cell processes, no 15 protofilament microtubules. Cloned: encodes alpha tubulin (pka tba-3).mec-12:lacZ expressed in touch cells, some other neurons also. [Chalfie and Au 1989\; NW\; SQ\; TU]"	
"mec-14"	"III"	-0.765363	"[C.elegansII] u55 : touch insensitive, lethargic. ES2. OA8: u82, u296 etc. [Chalfie and Au 1989\; Huang and Chalfie 1994\; TU]"	
"mec-15"	"II"	2.11624	"[C.elegansII] u215ts : touch insensitive, lethargic. ES2 (25C). OA4: u75, etc.(all alleles partially ts). [Chalfie and Au 1989\; Huang and Chalfie 1994\; TU]"	
"mec-17"	"IV"	3.6293	"[C.elegansII] u265 : larvae touch sensitive, older animals touch insensitive\; mec-3:lacZ expression not maintained in touch cells. NA1. [Chalfie and Au 1989\; Way and Chalfie 1989\; TU]"	
"mec-18"	"X"	-7.69485	"[C.elegansII] u228 : touch insensitive, lethargic.OA5: u69, u138, u182 etc. [Chalfie and Au 1989\; Huang and Chalfie 1994\; TU]"	
"mei-1"	"I"	2.64158	"[C.elegansII] b284 : Mel, embryonic lethality, abnormal oocyte meiosis leading to lethal aneuploidy. Normal male meiosis.OA>20: ct46dm,ts (gf allele, normal meiosis followed by abnormal mitoses), intragenic revertants of ct46 eg ct44ct99 (putative null, abnormal meiosis), ct46ct82 (antimorphic), ct46ct103 (viable, weak Him), additional phenotypic classes.  See also mei-2, mel-26, zyg-9. Cloned: two transcripts encoding 472 and 475 aa predicted proteins with similarity to ATPases. Antibody stains meiotic spindles I and II. [Mains et al. 1990, Clark-Maguire and Mains 1994\; HR]"	
"mei-2"	"I"	1.23978	"[C.elegansII] ct102 : Mel, embryonic arrest as mass of cells without morphogenesis\; abnormal oocyte meiosis\; dominant suppressor of mei-1(dm), mel-26(dm).OA1: ct98 (dominant suppressor of mei-1(dm), slight recessive Mel, weak Him, viable). [Mains et al. 1990\; HR]"	
"mek-2"	"I"	-5.55565	"[C.elegansII] n2678 : sterile, vulvaless\; suppresses Muv phenotype of let-60(gf).  OA: h294 (pka let-537),n2156 (both similar to n2678), n1859, n1989, n2537 (weaker allele, some fertility), n1859,n1989 (weak alleles, homozygous viable but much early larval lethality, rod-like morphology)\;q425 (pka glv-1, sterile vulvaless adult hermaphrodite, makes sperm but no oocytes, all VPC tertiary), ku114 (viable,suppresses let-60(gf)),etc. Cloned: 55\% identity to human MEK1. [Church et al. 1995\; Kornfeld et al. 1995\; Wu et al. 1995\; EJ\; KR\; MH\; MT]"	
"mel-1"	"II"	-0.334914	"[C.elegansII] it19 : strict maternal effect embryonic lethal.  OA1: b315. [Kemphues et al. 1988]"	
"mel-3"	"II"	-0.334914	"[C.elegansII] b281 : strict maternal effect embryonic lethal.  OA1: it8. [Kemphues et al. 1988]"	
"mel-8"	"II"	0.964738	"[C.elegansII] it39 : maternal effect embryonic lethal,71\% zygotic rescue by mating with males.OA>15: b312 (stronger allele, only 19\% rescue),it3, it27 (pka mel-6), t1120, t1152 etc. Highly mutable gene.  [Kemphues et al. 1988, GE]"	
"mel-9"	"II"	1.12565	"[C.elegansII] b293ts : maternal effect embryonic lethal, some escapers\; reasonable zygotic rescue. NA1. [Kemphues et al. 1988]"	
"mel-10"	"II"	0.579277	"[C.elegansII] it10 : maternal effect embryonic lethal (0.5\% hatch), no zygotic rescue.  NA1. [Kemphues et al. 1988]"	
"mel-11"	"II"	1.13538	"[C.elegansII] it26 : maternal effect embryonic lethal, extensive zygotic rescue.  NA1. [Kemphues et al. 1988]"	
"mel-12"	"II"	0.579277	"[C.elegansII] it42 : maternal effect embryonic lethal, leaky, some zygotic rescue.  NA1. [Kemphues et al. 1988]"	
"mel-13"	"II"	3.36759	"[C.elegansII] b306 : strict maternal effect embryonic lethal.  NA1. [Kemphues et al. 1988]"	
"mel-15"	"II"	5.49703	"[C.elegansII] it38 : maternal effect embryonic lethal,leaky.  OA1: it7ts (0.9\% egg hatch at 25C,extensive zygotic rescue). [Kemphues et al. 1988]"	
"mel-18"	"II"	3.37352	"[C.elegansII] b300 : maternal effect embryonic lethal, slight zygotic rescue.  NA1. [Kemphues et al. 1988]"	
"mel-19"	"II"	3.37352	"[C.elegansII] b310 : maternal effect embryonic lethal, leaky, no zygotic rescue.  NA1. [Kemphues et al. 1988]."	
"mel-22"	"II"	5.49703	"[C.elegansII] it30 : maternal effect embryonic lethal, no zygotic rescue.  NA1. [Kemphues et al. 1988]"	
"mel-23"	"III"	3.85653	"[C.elegansII] ct45dm,ts : dominant maternal effect lethalat 25C, recessive nonconditional lethal\; at 25C all embryos from ct45\/+ mothers have early defects, arrest at 28-cell stage.  Also dominant zygotic defects in male tail.  NA1. [Mains et al. 1990\; HR]"	
"mel-24"	"IV"	4.04961	"[C.elegansII] ct59sd,ts : dominant maternal effect lethal, variable\; at 25C many progeny from ct59\/+mothers arrest during embryogenesis\; homozygotes nonconditional Mel.  NA1. [Mains et al. 1990\; HR]"	
"mel-25"	"V"	2.90355	"[C.elegansII] ct60dm,ts : dominant maternal effect lethal at 25C, recessive nonconditional sterile\;at 25C progeny from ct60\/+ mothers have early defects, arrest at early morphogenesis.Also dominant zygotic defects in male tail. [Mains et al. 1990\; HR]"	
"mel-26"	"I"	3.55098	"[C.elegansII] ct61dm,ts : dominant maternal effect lethal, at 25C most embryos from ct61\/+ mothers have early cleavage defects, arrest prior to morphogenesis\; at 15C impenetrant maternal effect Vab.  More severe defects in progeny from homozygous mothers.OA1: revertant ct61sb4 is a recessive maternal-effect lethal. [Mains et al. 1990\; HR]"	
"mel-27"	"III"	-1.07992	"[C.elegansII] e2561mm : embryos arrest with about 100 cells that do not adhere to each other, and resemble a bag of marbles\; no tissue differentiation\; homozygous mutant mothers are slightly clear and sick, with hypodermis variably pulled away from cuticle along the body. NA1. [CB]"	
"mel-28"	"III"	-2.4537	"[C.elegansII] e2567mm : polar bodies sometimes large, mitotic spindles look weak\; DNA does not separate properly at mitotic divisions when viewed in tubulin\/DNA stained embryos\; globs of DNA can be seen at midbodies, and sometimes most of the DNA goes to one cell. NA1 [CB]"	
"mel-29"	"V"	2.15727	"[C.elegansII] e2596mm : embryos arrest as balls of cells with gut granules, twitching, hypodermis and neurons, but appear to lack pharyngeal tissue. NA1 [CB]"	
"mel-30"	"II"	2.01017	"[C.elegansII] e2595mm : embryos arrest as balls of cells with gut granules, twitching, hypodermis, and neurons, but apparently lack pharyngeal tissue\; founder cell divisions slow relative to P-cell divisions.  NA1. [CB]"	
"mel-31"	"III"	-2.2	"[C.elegansII] s2438 : variable sterile or Mel (embryoniclethal). NA1. [BC]"	
"mes-1"	"X"	6.35862	"[C.elegansII] bn7ts : grandchildless, at 25C, 70\% of progeny develop into sterile adults\;P2 and P3 divisions variably defective, P4 transformed into D-like muscle precursor,generating additional muscle cells, no germ cells.  OA9: bn74 (deletion null, ts impenetrant Mes resembling bn7), bn24, q222,etc. (all ts, impenetrant). Cloned: cosmid rescue C38D5. [Strome et al. 1995]"	
"mes-2"	"II"	22.988	"[C.elegansII] bn11 : grandchildless, progeny undergo normal embryogenesis but develop into agametic adults\;few germ cells made.  XO germ line less affected. Normal P granule staining. OA2: bn27, bn48. Cloned: 2.5 kb transcript, encodes SET domain protein, closest similarity to Drosophila Enhancer of zeste. [Capowski et al. 1991\; SS]"	
"mes-3"	"I"	-0.421414	"[C.elegansII] bn35 :  grandchildless, progeny undergo normal embryogenesis but develop into agametic adults\; few germ cells made. Normal P granule staining. XO germ line less affected. OA4: bn53 (stronger allele), bn21ts (100\% sterile 25C, 2\% 16C\; T-shift suggests action in early embryo). Cloned: 3.1 kb transcript, encodes novel protein. In operon with dom-3. [Capowski et al. 1991\; SS]"	
"mes-4"	"V"	5.29706	"[C.elegansII] bn50 : grandchildless, progeny undergo normal embryogenesis but develop into agametic adults(only 10 germ cells made). Normal P granule staining.   XO germ line much less affected.OA3: bn23, bn58, bn67 (all similar). [Capowski et al. 1991\; SS]"	
"mes-5"	"III"	-1.6384	"[C.elegansII] bn37ts : grandchildless, progeny undergo normal embryogenesis but develop into agametic adults. [Capowski et al. 1991\; SS]"	
"mes-6"	"IV"	3.89444	"[C.elegansII] bn66 :  grandchildless, progeny undergo normal embryogenesis but develop into agametic adults. OA3: bn38, bn64, bn69. Cloned: encodes predicted protein with WD40 repeats.In operon with dom-6. [Capowski et al. 1991\; SS]"	
"mev-1"	"III"	2.43	"[C.elegansII] kn1 : four-fold increase in paraquat sensitivity\; hypersensitive to high oxygen concentration\; reduced broodsize, reduced lifespan, increased age-associated fluorescence\; rare supernumerary divisions in gut cells. [Honda et al. 1993\; TK\; TM]"	
"mev-1"	"III"	2.43	"[C.elegansII] NMK. Transcripts 2.1 kb (cyt-1 + ced-9) and0.75 kb\; encodes 182 aa presumptive cytochrome b560\;3' end overlaps ced-9, shared regulation. [Hengartner and Horvitz 1994\; MT\; WS]"	
"mev-2"	"X"	-18.4782	"[C.elegansII] kn2 : increased paraquat sensitivity. [TK\; TM]"	
"mev-3"	"I"	0.589622	"[C.elegansII] kn3 : increased paraquat sensitivity, hypersensitive to oxygen. [TK\; TM]"	
"mex-1"	"II"	4.5	"[C.elegansII] zu121 :  maternal effect lethal mutation, which results in  four AB granddaughters of the eight cell stage embryo following a pattern of development nearly identical to the posterior blastomere MS. This results in embryos which produce excess muscle and pharynx. OA9: zu120, zu122, zu140, zu173, zu221it9 (pka mel-21)[Mello et al. 1992\; JJ\; KK]"	
"mex-3"	"I"	-17.4207	"[C.elegansII] zu142 : maternal effect lethal mutations which results in the production of excess muscle. The excess muscle is derived from the anterior blastomere AB of the two cell stage embryo. OA8: zu155, zu203, zu205, zu208, zu211, etc. Cloned: encodes novel predicted protein with two KH domains.  mRNA accumulates at anterior pole of zygote after fertilization. [JJ]"	
"mig-1"	"I"	-16.4817	"[C.elegansII] e1787 : abnormal migration of Q neuroblasts (both QL and QR migrate anteriorly)\; HSN migration also abnormal\; Egl. ES1. OA3: n1354, n1654. [Hedgecock et al. 1987\; Desai et al. 1988\; NJ]"	
"mig-2"	"X"	4.75	"[C.elegansII] rh17 : variable abnormal migration of Q neuroblasts, HSN cells,  CAN cells etc.\; Egl\; uncoordinated\; axon defects.  OA1. [Hedgecock et al. 1987\; Desai et al. 1988\; NJ]"	
"mig-5"	"II"	0.688089	"[C.elegansII] rh147ts,mat : complex phenotype, abnormal cell migrations\; cell lineage and cell fate defects\; often two linker cells in male\; rh147\/Df similar.  Both maternal and zygotic rescue.  OA1: rh94 (weaker). Cloned: encodes predicted 666 aa intracellular protein, 3 domains with high similarity to Drosophila dsh, discs large. [Hedgecock et al. 1987\; NJ]"	
"mig-6"	"V"	0.880972	"[C.elegansII] e1931 : distal tip cells fail to migrate, sterile.  OA2: oz90, oz113[Hedgecock et al. 1987\; NJ\; BS]"	
"mig-8"	"X"	-2.10285	"[C.elegansII] rh50 :  distal tip cells fail to reflex, fail to express unc-5:lacZ.  See also daf-12. [Hedgecock et al. 1987\; NJ]"	
"mig-10"	"III"	-0.31445	"[C.elegansII] ct41 : incomplete CAN, HSN, ALM migrations\; shortened excretory canals\; additional defects.  Mosaic analysis indicates non-autonomy, possible hypodermal focus.  OA1: e2527. Cloned: encodes predicted 650 aa protein with similarity to human Grb7, Grb10, including pleckstrin homology domain. [Desai et al. 1988\; LK]"	
"mig-11"	"III"	-1.43981	"[C.elegansII] ct78 : defective CAN migrations\; other migrations defective at low penetrance. [LK\; CX]"	
"mig-13"	"X"	-5.83687	"[C.elegansII] mu31 : defects in migration of cells descended from QR. Positions of a few other cells (BDU, ALM, left coelomocytes) sometimes abnormal. HSN wildtype. [CF]"	
"mig-14"	"II"	20.7853	"[C.elegansII] mu71 : QL descendants migrate to anterior, QR descendants and HSNs have shortened migrations, BDU posteriorly displaced. Mild Egl. [CF]"	
"mig-15"	"X"	1.97	"[C.elegansII] rh148 : QL migration resembles QR. Pleiotropic defects in hypodermis. [CF]"	
"mix-1"	"II"	3.058	"[C.elegansII] mn29 : late larval lethal. OA2: b285 (Mel), mn182. [Sigurdson et al. 1984\; Kemphues et al. 1988]"	
"mlc-1"	"X"	24.1203	"[C.elegansII] Deletions (eg sup-10(n184)) viable, normal muscle\; increased lethality of mlc-2(0).Resembles mammalian non-muscle MLC\; expressed in both pharynx and body wall.  Not transpliced. [Cummins and Anderson 1988\; TR]"	
"mlc-2"	"X"	24.1199	"[C.elegansII] Deletion exhibits pharyngeal pumping defect,10\% reach fertile adulthood (most males reach adulthood).  Deletion of both mlc-1 and mlc-2 leads to lethal arrest as short lumpy paralysed L1\/L2.  Resembles mammalian non-muscle MLC\; expressed in both pharynx and body wall\; SL1transpliced. [Cummins and Anderson 1988\; Rushforth et al. 1993\; TR]"	
"mog-1"	"III"	1.05109	"[C.elegansII] q223 : hermaphrodite germline makes 300-500 sperm, no oocytes\; no somatic defects\; males WT. q223\/Df similar. OA5: q151, q161, q370, q471 (all similar),q473 (viable, some oogenesis, more at 15C). mog-1\; fem-1 or mog-1\; fem-3 double mutant hermaphrodites make oocytes, but are Mel (variable embryonic arrest). [Graham and Kimble 1993]"	
"mog-2"	"II"	-4.56621	"[C.elegansII] q75 : ts Mog, at 25C  hermaphrodite germline makes mostly sperm, rare abnormal oocytes. Mostly fertile at 15 degrees, but no viable progeny (Mel). Also Mel if feminized by fem-3. NA1. [Graham et al. 1993]"	
"mog-3"	"III"	-2.63145	"[C.elegansII] q74 : ts Mog, at 25C , most hermaphrodites make only sperm, 13\% make ooids. At 15 degrees fertile but Mel. Also Mel if feminized by fem-3. NA1. [Graham et al. 1993]"	
"mog-4"	"II"	24	"[C.elegansII] q233 : ts Mog, at 25C incompletely penetrant Mog: hermaphrodite germline makes mostly sperm, some abnormal oocytes. At 15 degrees sterile, non-Mog. Mel if feminized by fem-3. NA1. [Graham et al. 1993]"	
"mog-5"	"II"	-0.86	"[C.elegansII] q449 : ts Mog, at 25C  fully penetrant Mog: hermaphrodite germline makes only sperm. At 15 degrees sterile non-Mog. Mel if feminized by fem-3. NA1. [Graham et al. 1993]"	
"mog-6"	"II"	3.49883	"[C.elegansII] q465 : ts Mog, at 25C fully penetrant Mog: hermaphrodite germline makes only sperm. At 15 degrees sterile non-Mog. Mel if feminized by fem-3. NA1. [Graham et al. 1993]"	
"mom-1"	"X"	-3.11784	"[C.elegansII] Mutations lead to maternal effect lethality, embryos arrest with extra pharyngeal tissue like that derived from MS\; possible E to MStransformation.  OA3. [JJ]"	
"mor-1"	"III"	1.39129	"[C.elegansII] e1071 : head less pointed than wildtype, slightly rounded nose, especially at 25C. ES2 (adult) ME3. NA1. [Lewis and Hodgkin 1979\; Hodgkin 1983a]"	
"mor-2"	"IV"	2.4	"[C.elegansII] e1125 : head less pointed than wildtype, rounded nose. ES2 (adult). ME3. OA1: e2015 (similar). [Hodgkin 1983a]"	
"mpk-1"	"III"	-3.93	"[C.elegansII] ku1 : (pka sur-1) suppresses activated ras(let-60(gf), variable Vul, cs Egl, rod-like early larval lethality phenotypes\; impenetrant defects in P6.p lineage.OA>10: ku30 (lineage defects), ku33, ku34, ku38(all Egl), n2521 (activated ras suppressor, normal lineage alone, mosaic analysis indicates cell autonomy), pk79tci etc. Cloned: Encodes 375 aa predicted protein, 75-80\% identical to mammalian MPK, closest to ERK2 subfamily. [Lackner et al. 1994\; Wu and Han 1994\; MH\; MT\; SD]"	
"mua-1"	"II"	-0.052302	"[C.elegansII] rh160 : progressive paralysis, with loss of muscle-to-cuticle attachments\; both muscle-muscle and muscle-hypodermis links lost from L2 onward\; may lead to secondary Gon, Egl defects etc.\; detachment suppressed by muscle mutants such as unc-54.  rh160\/Df similar. NA1. Cloned: encodes predicted 246 aa protein with three zinc fingers, Sp1  family.  [NJ]"	
"mua-2"	"III"	10.2463	"[C.elegansII] rh119 : progressive detachment of muscles during larval development. [NJ]"	
"mua-3"	"III"	1.85358	"[C.elegansII] rh169 :  progressive detachment of muscles during larval development, possibly defective in reformation of muscle-cuticle links at each molt. Cloned: encodes predicted 3617 aa protein with TM domain, large extracellular domain containing 52 EGF repeats, 5 LDL repeats, etc. [NJ]"	
"mua-4"	"III"	-1.99991	"[C.elegansII] rh177 : progressive detachment of muscles during larval development. [NJ]"	
"mua-6"	"X"	23.4053	"[C.elegansII] rh85 : progressive paralysis, defective muscle attachments like Mua-1\;  poor growth\; most homozygotes arrest as larvae\; adults Egl\; Smg suppressible.  NA1. [NJ]"	
"mud-1"	"III"	-3.28822	"[C.elegansII] qm21 : hatchlings of variable length, very poor movement\; adults short, kinky Unc\; very high embryonic and larval lethality\; full zygotic and maternal rescue, except for incomplete maternal rescue of Dpy phenotype.OA1: qm22. [MQ]"	
"mum-1"	"IV"	4.62945	"[C.elegansII] qm32 : variably deformed body, pharynx\; severe Unc, strong kinker or paralysed\; defects in neuroanatomy, excretory system,gonads\; high embryonic and larval lethality\; extensive (>95\%) maternal and zygotic rescue\; qm32\/Df lethal.  NA1. [MQ]"	
"mum-2"	"IV"	4.35157	"[C.elegansII] qm33 : variably deformed body, pharynx\; severe Unc, strong kinker or paralysed\; defects in neuroanatomy, excretory system, gonads\; high larval lethality\; extensive (>95\%) maternal and zygotic rescue\; qm33\/Df sterile.  NA1. [MQ]"	
"mum-3"	"III"	2.84046	"[C.elegansII] qm46 : variably deformed body, pharynx\; severe Unc, strong kinker or paralysed\; defects in neuroanatomy, excretory system, gonads\; some larval lethality\; complete maternal and zygotic rescue.  NA1. [MQ]"	
"mup-1"	"II"	-7.76499	"[C.elegansII] e2430ts : viable, inappropriately attached or detached muscles\; dumpy\; phenotype least severe at 20C\; suppressed by dpy-2,-10,-11\; some maternal rescue\; weakest allele. OA9: e2485ts, e2436, e2347, e2434, e2439 (strong allele, mostly embryonic arrest at 3-fold stage or kinked L1, extensive misattachment of muscles),etc. [Goh and Bogaert 1991]"	
"mup-2"	"X"	-2.86844	"[C.elegansII] e2346ts : embryonic temp-shift leads to lethal mispositioning and deformity of body-wall muscle\; larval temp-shift leads to sterility, defects in oviduct muscle. OA1: up1 (non-conditional, lethal with arrest as kinked larva\; probable null, nonsense mutation). Cloned: encodes troponin T homolog. [EE\; UG]"	
"mup-4"	"III"	-0.6	"[C.elegansII] mg36 : lethal, embryonic arrest at 3-fold, defective muscle attachment, abnormal hypodermis\; muscle cells collapse from ventral side, retract from head and tail\; some embryos arrested earlier. Mosaic analysis indicates focus in AB.  OA>5: ar60, mg23, mg36, s2433 etc. [BC\; EE\; GR]"	
"myo-3"	"V"	3.79716	"[C.elegansII] st386 : severe Pat (paralysed embryonic arrest at two-fold stage)\; very abnormal muscle ultrastructure, no MYO-3 staining.OA2 (Pat): st563, st565. Also duplication alleles: e1407sd(pka sup-3, partial suppressor of certain mutations of muscle genes unc-15, unc-54, unc-87), e1390, etc.\;   Also super-suppressor alleles (unstable).  All probably tandem duplications or further amplifications of myo-3. [Dibb et al. 1989\; Maruyama et al. 1989\; Williams and Waterston 1989]"	
"ncl-1"	"III"	-0.609847	"[C.elegansII] e1865 : abnormal large nucleoli in all cells. ES1. OA1 (e1942 : similar phenotype). Cell autonomous, widely used cell marker for mosaic analysis. [Herman 1989\; Hedgecock and Herman 1995\; NJ]"	
"ncl-2"	"IV"	4.14229	"[C.elegansII] e1896 : abnormal refractile nucleoli especially in germ cells\; few ribosomes, abnormal nucleoli seen in EM sections\; progressive deterioration\; sterile. ES2. NA1. [NJ]"	
"nob-1"	"III"	14.4138	"[C.elegansII] ct223 : early L1 lethal with normal head, spherical gut, round posterior\; defect in E cell arrangement at 100 cell stage.  Affects pal-1:lacZ expression. ct223\/Df similar.OA2: ct351 (similar), ct230 (weaker, viable\;abnormal tail, 65\% fertile\; males have missing rays, crumpled spicules). [BW]"	
"nob-3"	"I"	3.70139	"[C.elegansII] ct315 : homozygotes L1 or embryonic lethal, malformed posterior. Cloned: cosmid rescue. [BW]"	
"nop-1"	"III"	-1.5	"[C.elegansII] it142mat : embryos from homozygous nop-1 mothers have no pseudocleavage contractions or furrow during the first cell cycle\; abnormal actin distribution\; normal cytoplasmic streaming and partition\; 79\% of embryos hatch and grow into fertile adults [Rose et al. 1995]"	
"nuc-1"	"X"	7.01134	"[C.elegansII] e1392amb : major endodeoxyribonuclease reduced >95\%\; condensed chromatin persists after programmed cell death DNA in intestinal lumen not degraded. ES1 ME3. OA2: n887 (resembles e1392), n334 (weaker allele). [Hedgecock et al. 1983\; Ellis et al. 1991\; MT]"	
"odr-1"	"X"	12.4566	"[C.elegansII] n1930 : defective chemotaxis to some volatile odorants.  OA2: n1933, n1936 (similar). [Bargmann et al. 1993]"	
"odr-2"	"V"	0.627095	"[C.elegansII] n1939 : defective chemotaxis to some volatile odorants.  n1939\/Df similar.  OA2: n2148, n2145. Cloned: encodes predicted ~200 aa protein, GPI-linked. [Bargmann et al. 1993\; CX]"	
"odr-3"	"V"	4.96	"[C.elegansII] n2150 : reduced response to all volatile odorants\; defective osmotic avoidance\; some chemotactic defects.  Cilia of sensory neuron AWC stunted.  OA1: n2046 (weaker phenotypes). [Bargmann et al. 1993]"	
"odr-4"	"III"	-1	"[C.elegansII] n2144 : defective chemotaxis to some volatile odoratants.  n2144\/Df similar.  NA1. [Bargmann et al. 1993]"	
"odr-5"	"X"	1.66366	"[C.elegansII] ky9 : defective chemotaxis to some volatile odorants, same subset as Odr-1.  NA1. [Bargmann et al. 1993]"	
"odr-7"	"X"	7.7	"[C.elegansII] ky4 : defective chemotaxis to some volatile odorants\; nonsense mutant.  OA1: ky55 (defective chemotaxis to diacetyl, other responses normal\; missense). Cloned: encodes predicted protein with similarity to NHR DNA-binding domain\; odr-7:GFP expressed only in AWA sensory neurons. [Sengupta et al. 1994, CX]"	
"odr-10"	"X"	-2.40454	"[C.elegansII] ky32 : diacetyl response defective. [CX]"	
"ooc-1"	"II"	3.04935	"[C.elegansII] mn250mat mm : hermaphrodites lay fertilized eggs that do not hatch. ES3 (progeny). NA1. [Sigurdson et al. 1984]"	
"ooc-2"	"II"	0.595787	"[C.elegansII] mn249mat mm : hermaphrodites lay fertilized eggs that do not hatch. ES3 (progeny).NA1. [Sigurdson et al. 1984]"	
"ooc-3"	"II"	3.5388	"[C.elegansII] mn241mat mm : hermaphrodites lay fertilized eggs that do not hatch. ES3 (progeny). NA1. [Sigurdson et al. 1984]"	
"ooc-4"	"III"	2.32128	"[C.elegansII] e2078 : sterile, abnormal or missing oocytes\; some spermatogenesis\; males fertile. [CB]"	
"osm-1"	"X"	23.9852	"[C.elegansII] p808 : fails to avoid 4M fructose or 4M NaCl\; poor chemotaxis to NaCl\; normal thermotaxis\; fails to take up FITC\; Daf-d\; severely shortened axonemes, ectopic assembly of ciliary structures and microtubules in many sensory  neurons. ES1 ME2. OA>10: p816 (similar phenotype, lower fertility), e1803, e1804, p808, p816, m530mut etc. Cloned: encodes predicted 1738 aa protein, very acidic\; related to human brain protein of unknown function. [Perkins 1986\; Starich et al. 1995]"	
"osm-3"	"IV"	-2.25348	"[C.elegansII] p802 : fails to avoid 4M fructose or 4M NaCl\; non-chemotactic\; defective dauer formation\; normal thermotaxis\; fails to take up FITC\; eliminates distal segment of amphid channel\; cilia in other ciliated neurons normal\; octopamine-deficient. ES1 ME3. OA>7: e1806, e1811, hf3 (pka caf-1, resistant to 30 mM caffeine, Dyf), etc. Cloned: encodes 672 aa kinesin-like protein, osm-3:lacZ expressed in all 26 sensory neurons with external openings. [Tabish et al. 1995\; Starich et al. 1995]"	
"osm-5"	"X"	-12.302	"[C.elegansII] p813 : fails to avoid 4M fructose or 4M NaCl\; poor chemotaxis to NaCl\; normal thermotaxis\; fails to take up FITC\; Daf-d\; severely shortened axonemes, ectopic assembly of ciliary structures and microtubules in many sensory neurons\; also males suicidal, poor mating. ES1 ME1. OA>6: m184, mn397 [Perkins et al. 1986\; Starich et al. 1995\; SP\; DR]"	
"osm-6"	"V"	3.44991	"[C.elegansII] p811 : fails to avoid 4M fructose or 4M NaCl\; poor chemotaxis to NaCl\; normal thermotaxis\; fails to take up FITC\; Daf-d\; severely shortened axonemes, ectopic assembly ofciliary structures and microtubules in many sensory neurons.ES1 ME1. OA>6: m511, m533mut. Cloned: cosmid R07A10. [Perkins et al. 1986\; Starich et al. 1995\; SP\; DR]"	
"osm-7"	"III"	21.4083	"[C.elegansII] n1515 : defective osmotic avoidance\; defective chemotaxis\; slow pharyngeal pumping\; FITC uptake normal.  NA1. [CX\; MT\; JT]"	
"osm-8"	"II"	0.684796	"[C.elegansII] n1518 : defective osmotic avoidance.  NA1. [MT\; JT]"	
"osm-9"	"IV"	-3.38649	"[C.elegansII] n1601 : defective in osmotic avoidance, also in nose touch avoidance (Not)\; Adp (partly defective adaptation to isoamyl alcohol and butanone)\; normal chemotaxis.OA5: n1516, n1603, n2473, ky10 (similar). [Colbert & Bargmann 1995\; JT\; KP\; MT]"	
"osm-10"	"III"	-0.657133	"[C.elegansII] n1602 : specifically defective in osmotic avoidance\; normal chemotaxis\; normal garlic avoidance\; normal nose touch response.  NA1. Cloned: cosmid rescue [Bargmann et al. 1990\; CX, KP]"	
"osm-11"	"X"	23.4871	"[C.elegansII] n1604 : defective osmotic avoidance.  NA1. [MT\; JT]"	
"osm-12"	"III"	13.4511	"[C.elegansII] n1601 : defective osmotic avoidance.  NA1. [MT\; JT]"	
"pag-1"	"III"	-1.94467	"[C.elegansII] ls2 : homozygotes exhibit overexpression of mec-7 - lacZ fusion transgene\; recessive. Some additional axonal defects. ES1. OA4. [EA]"	
"pag-3"	"X"	19.5053	"[C.elegansII] ls20 : homozygotes exhibit misexpression of the mec-7 gene, mec-7lacZ and mec-4lacZ fusion genes in the BDU neurons. Also causes a reverse kinker uncoordinated phenotype, and occasional axonal guidance errors in the PLM and BDU neurons. NA1. [EA]"	
"pal-1"	"III"	-2.829	"[C.elegansII] e2091 : adult males lack V6-derived rays, alae extend into tail region\; V6 lineage transformed into  V1-V4\; cell autonomous action\;variable additional defects, some embryonic lethality.OA3: mu13 (similar to e2091), ct224 (pka nob-2, lethal with arrest at hatching, severely deformed posterior, deletion null), ct281. Cloned: 1.25 and 1.45 kb transcripts,  encode homeoprotein  (pka ceh-3) with similarity to Drosophila caudal, mouse cdx-1. [Waring and Kenyon 1991\; Waring et al. 1992\; CF\; BW]"	
"pal-2"	"IV"	3.72166	"[C.elegansII] e2260 : adult males have ectopic alae extending into tail region\; slight ray abnormalities and mispositioning\; tail seam probably transformed to body seam\; e2260\/Df similar.  Hermaphrodite WT.  ME2.  NA1. [Hodgkin et al. 1989\; CB]"	
"par-1"	"V"	5.86	"[C.elegansII] b274mat : homozygous hermaphrodites produce embryos that arrest with many differentiated cells, no detectable gut granules\; first cleavage symmetrical, defective P granule localization. ES3 (progeny). OA>10: it51, it90 (both missense changes in kinase domain),e2012, it32, it102, lw7 (leaky, Mes), lw39gri (deletion) etc. Cloned: 4.4 kb transcript, germline enriched, encodes predicted 1192 aa Ser\/Thr kinase. Antibody staining indicates 126 kD protein with specific asymmetric membrane localizations in early blastomeres [Kemphues et al. 1988\; Guo and Kemphues 1995\; JJ\; KK]"	
"par-2"	"III"	-24.6796	"[C.elegansII] it46ts,mat : homozygous hermaphrodites produce 90\% (16C) to 99\% (25C) arrested embryos, escapers sterile\; abnormal early cleavages, both spindles transverse at 2nd cleavage (failure of P1 rotation), defective P granule localization. ES3 (progeny). OA7: it5ts (weaker phenotype), e2030 (Mes, grandchildless),it87 (weak),jb2, etc.  All ts\; temp shift indicates not needed after 2nd cleavage. Cloned: encodes predicted novel protein. Antibody staining indicates specific asymmetric cortical localizations in early blastomeres. [Cheng et al. 1995\; KK]"	
"par-3"	"III"	-1.4518	"[C.elegansII] e2074amb : maternal effect lethal mutation, affects first two embryonic cell cycles\; abnormal pseudocleavage, streaming, P granule localization\;  2nd cleavage spindle orientation variable, often both longitudinal (ectopic rotation in AB).OA5: it54 (leaky, Mes), it71amb (null), it62, it91. Cloned: encodes predicted 138 kD novel protein. Antibody staining indicates specific asymmetric peripheral localizations in early blastomeres. [Cheng et al. 1995\; KK]"	
"par-4"	"V"	13.7803	"[C.elegansII] it47ts : maternal effect lethal at 25C\; arrest as multicellular mass, no morphogenesis, no gut granules\; abnormally small and round eggs\; abnormal early cleavages, etc. \;4\% hatch at 15C, develop to sterile adult.OA9: it33 (nonconditional, fully penetrant Mel\;putative null)\; it57ts (viable at 15C, Mel at25C), it74, it75, it120, etc. [Morton et al. 1992\; KK]"	
"par-5"	"IV"	5.31234	"[C.elegansII] it55 : maternal effect lethal\; 2nd cleavage spindles transverse, asters spherical (resembles Par-2)\; most embryos lack gut granules. OA1. [Morton et al. 1992\; KK]"	
"par-6"	"I"	13.8814	"[C.elegansII] zu170spo : maternal effect lethal, resembles Par-3 but terminal arrest with more gut differentiation\; improper P granule localization. Dominant suppressor of weak par-2 mutations.OA2: zu174, zu222. [JJ\; KK]"	
"pat-2"	"III"	-0.020783	"[C.elegansII] st543 : severe Pat phenotype\; disrupted assembly of myofilament lattice.  OA6: st422, st538, st567 (weaker, some pharyngeal pumping), etc. Cloned: encodes alpha integrin. [Williams and Waterston 1994\; RW]"	
"pat-3"	"III"	-4.40333	"[C.elegansII] st423 : severe Pat phenotype, disrupted myofilament lattice.  OA>8: st564 (weaker allele), st423, st552, st564, rh54 (embryonic lethal, mosaic analysis indicates autonomous defects in cell attachment, morphogenesis, etc.),rh151 (sterile), rh96 (mild\; short excretory canals, varible Mig defects). Cloned: 3kb transcript, encodes beta integrin. [Williams and Waterston 1994\; Gettner et al. 1995\; CF\; NJ\; RW]"	
"pat-4"	"III"	-27.1637	"[C.elegansII] st552 : severe Pat phenotype. OA3: st551, st579, st580 (all similar). [Williams and Waterston 1994\; RW]"	
"pat-6"	"IV"	-27.8745	"[C.elegansII] st561 : severe Pat phenotype. OA1:st570 (weaker, some pharyngeal pumping). [Williams and Waterston 1994\; RW]"	
"pat-8"	"IV"	2.97314	"[C.elegansII] st554 : severe Pat phenotype\; some pharyngeal pumping. [Williams and Waterston 1994\; RW]"	
"pat-9"	"X"	23	"[C.elegansII] st558 : severe Pat phenotype\; some pharyngeal pumping. [Williams and Waterston 1994\; RW]"	
"pat-10"	"I"	-0.51312	"[C.elegansII] st568 : severe Pat phenotype\; some pharyngeal pumping. OA1: st575. Probably corresponds to tnc-1, encoding troponin C. [Williams and Waterston 1994\; HK\; RW]"	
"pat-11"	"I"	0.4407	"[C.elegansII] st541 : mild Pat phenotype\; paralysed pharyngeal muscles. [Williams and Waterston 1994\; RW]"	
"pat-12"	"III"	-26.5563	"[C.elegansII] st430 : mild Pat phenotype\; some pharyngeal pumping. [Williams and Waterston 1994\; RW]"	
"pbo-1"	"III"	-3.28516	"[C.elegansII] sa7 : posterior body contraction during defecation very weak or absent\; aBoc and Exp steps, and cycle period, normal\; constipated\; very slow growing.  NA1. [Thomas 1990\; JT]"	
"pex-1"	"I"	10.5	"[C.elegansII] dx8 : sterile, pachytene exit blocked in hermaphrodite oogenesis, germline phenotype resembles mpk-1and mek-2 mutants. NA1. [EJ]"	
"pha-1"	"III"	5.97577	"[C.elegansII] e2123ts : at 25C zygotic embryonic lethal, pharynx fails to undergo late differentiation and morphogenesis\; early pharynx development normal.  OA>5: e2468 (unconditional), t1001ts,e2286 (weak, 38\% hatch and arrest), t1002 (weak,some survival to late larval arrest), etc.See also extragenic suppressors sup-35, sup-36, sup-37. Cloned: 2.2kb embryonic transcript, encodes 491 aa predicted protein with some similarity to bZIP transcription factors\; pha-1:lacZ expressed transiently in all pharyngeal precursor cells. [Granato et al. 1994\; GE]"	
"pha-2"	"X"	-19.4189	"[C.elegansII] ad572 : misshapen pharynx.  Worms hatch with pharynx of correct gross shape, but disorganized, with nuclei misplaced. Most homozygotes arrest in L1\; escapers grow up to become very starved adults with deformed pharynges with abnormally small terminal bulb, thick nucleated isthmus. Weakly cs (more survival beyond L1 at 25C than at 15C).  ES2, ME3.  NA1. [Avery 1993\; DA]"	
"pha-3"	"IV"	5.54033	"[C.elegansII] ad607 : misshapen pharynx, isthmus tapered,thinner at the front, rather than uniform\; corpus also deformed\; metacorpus often open when relaxed.  No larval arrest, very slow growth.  ad607\/Df grow more slowly, usually or always sterile. ES2.  NA1. [Avery 1993\; DA]"	
"pha-4"	"V"	25.1732	"[C.elegansII] q490 : zygotic lethal, embryonic arrest with no pharynx, absence of pharyngeal antigens, intestine not connected to rectum, some rectal cells often missing\; most embryos fail to elongate.  q490\/Df similar.  OA6: q400, n2498, q506 (similar), q500 (weaker), etc. [Mango et al. 1994\; JK]"	
"phm-2"	"I"	9.32586	"[C.elegansII] ad538 : pharyngeal grinder cannot assume full forward position, terminal bulb muscles appear short (too strong?)\; space behind the grinder is usually distorted into a continuously open cavity\; male spicules protrude.ES2, ME0. OA1: ad597. [Avery 1993\; DA]"	
"phm-3"	"III"	-13.7153	"[C.elegansII] ad493 : pharyngeal muscle birefringence reduced, pharyngeal contractions are feeble. ES1, ME3, NA1. [Avery 1993\; DA]"	
"pho-1"	"II"	-1	"[C.elegansII] ca101 : electrophoretic variant in major acidphosphatase, no other phenotype.  NA1. Purified protein is homodimeric glycoprotein,55kD subunit\; activity detected at luminal edge of most gut cells, but not 6 most anterior. [Beh et al. 1991\; JM]"	
"pie-1"	"III"	17.6306	"[C.elegansII] zu154 : maternal effect lethal, often with two distinct pharynges\; additional pharynx and intestinal tissue from P2 (transformed to EMS fate).OA1. Cloned: encodes zinc finger protein, localized to nuclei of germ line blastomeres. [Mello et al. 1992\; Mango et al. 1994\; EU\; JJ]"	
"plg-1"	"III"	0.644949	"e2001dm spo : males lay down gelatinous blob over vulva of mated hermaphrodites\; allele isolated from natural C. elegans strain Cal-5. ES1 ME3. NA1."	
"plg-1"	"III"	0.644949	"[C.elegansII] e2001dm,spo : males lay down gelatinous blob over vulva of mated hermaphrodites\; allele isolated from natural C. elegans strain from Stanford, CA. ES1 ME3. NA1. [Barker 1994\;  CB]"	
"pop-1"	"I"	-6	"[C.elegansII] zu189mut : maternal effect embryonic lethal,no MS-derived pharyngeal cells\; MS blastomere adopts the fate of sister blastomere E\; resulting embryos have twice the wildtype amount of gut.  NA1. Cloned: encodes predicted 487 aa protein with HMG box\;  antibody stains nuclei of oocytes, early blastomeres. [Lin et al. 1995\; JJ]"	
"pry-1"	"I"	22.1746	"[C.elegansII] mu38 : adult males make no alae but instead have ectopic rays. Hermaphrodites are sometimes Muv. The descendants of QR stay in the posterior. The postderid is often missing. Causes late ectopic expression of lin-39, mab-5, and egl-5.  See also spy. [CF]"	
"ptp-2"	"II"	-0.88	"[C.elegansII] NMK.  Encodes predicted protein related to SH2-containing Tyrosine Phosphatases family. [CGC]"	
"pvp-1"	"X"	3.01309	"[C.elegansII] rh114 : PVP axons fail to stain with mAb44.  No other phenotype detected. [NJ]"	
"rab-3"	"II"	-1.23029	"[C.elegansII] y250 : mild Unc, Che, Egl defects\; Ric.OA1: y251 (similar\; both y250 and y251 are missense alleles).   Encodes homolog of mammalian rab3 (73\% identity to human Rab3a).  Dominant negative transgene leads to Ric, some Unc, or L1 lethality like cha-1(0). [NM]"	
"rad-1"	"I"	6.15292	"[C.elegansII] mn155 : extremely hypersensitive to UV, X and gamma irradiation\; not  hypersensitive to UV-psoralen. ES1 ME3. NA1. [Hartman and Herman 1982\; Hartman and Marshall 1992\;PH]"	
"rad-2"	"V"	1.10021	"[C.elegansII] mn156 : extremely hypersensitive to UV, X and gamma irradiation\; some sensitivity to chronic MMS treatment\; not hypersensitive to UV-psoralen.  ES1 ME3. NA1. [Hartman and Herman 1982\; Hartman and Marshall 1992\;PH]"	
"rad-3"	"I"	1.48235	"[C.elegansII] mn157 : extremely hypersensitive to UV, not to X irradiation\; hypersensitive to chronic MMS treatment (L1 arrest in 0.1 mM)\; reduced brood size (58\% of wildtype)\; reduced photoproduct excision\; not hypersensitive to UV-psoralen. ES1 ME3. [Hartman et al. 1989\; Hartman and Marshall 1992\; PH]"	
"rad-4"	"V"	-9.46258	"[C.elegansII] mn158cs : hypersensitive to UV and to acute MMS treatment, not to X irradiation\; reduced X chromosome nondisjunction (partly suppresses some him mutations)\; reduced brood size (34\% of wildtype at 20C)\; < 25\% eggs hatch at 15C. ES1 ME2. NA1. [Hartman and Herman 1982\; PH]"	
"rad-6"	"III"	3.50598	"[C.elegansII] mn160 : hypersensitive to UV and X irradiation\; not to MMS\; hermaphrodites less viable (< 50\%) than males at 25C, equal viability at 15C. ES1 ME3. NA1. [Hartman and Herman 1982\; PH]"	
"rad-7"	"IV"	6.07232	"[C.elegansII] mn161 : hypersensitive to UV not to X irradiation or MMS. Reduced brood size (25\% of wildtype). Not hypersensitive to UV-psoralen.  ES1 ME3 NA1. [Hartman and Herman 1982\; Hartman and Marshall 1992\;PH]"	
"rad-8"	"I"	0.543256	"[C.elegansII] mn163 : hypersensitive to UV not to X irradiation or MMS. Reduced brood size (7\% of wildtype), young hermaphrodites lay many inviable eggs. Hypersensitive to paraquat, high oxygen concentration (lethal at 60\%) (see also mev)\; increased lifespan at 16C.ES1 ME0. NA1. [Hartman and Herman 1982\; Ishii et al. 1994\; TJ\; TK\; PH]"	
"ram-1"	"I"	9.91997	"[C.elegansII] bx34 : adult males have lumpy, amorphous ray morphology\; bx34\/+ has variably swollen raytips\; fails to complement unlinked ram mutations\;hermaphrodite WT.  ME3.  NA1. [Baird and Emmons 1990\; PB]"	
"ram-2"	"II"	1.75306	"[C.elegansII] bx39ts : adult males have lumpy, amorphous ray morphology\; bx39\/+ has variably swollen raytips\; fails to complement unlinked ram mutations\;hermaphrodite WT.  ME3.  NA1. [Baird and Emmons 1990\; PB]"	
"ram-3"	"II"	20	"[C.elegansII] bx32 : adult males have lumpy, amorphous ray morphology\; bx32\/+ has variably swollen raytips\; fails to complement unlinked ram mutations\;hermaphrodite WT.  ME3.  NA1. [Baird and Emmons 1990\; PB]"	
"ram-4"	"IV"	-0.192923	"[C.elegansII] bx25ts : adult males have lumpy, amorphous ray morphology\; bx25\/+ has variably swollen raytips\; fails to complement unlinked ram mutations\;hermaphrodite WT.  bx25\/Df similar.  ME3.  NA?: bx48, bx56ts (possible alleles). [Baird and Emmons 1990\; PB]"	
"ram-5"	"X"	17.7315	"[C.elegansII] bx30 : adult males have lumpy, amorphous ray morphology\; bx30\/+ has variably swollen raytips\; fails to complement unlinked ram mutations\;hermaphrodite WT.  ME3.  NA1. [Baird and Emmons 1990\; PB]"	
"rec-1"	"I"	30	"[C.elegansII] s180 : increases meiotic recombination in gene clusters, reduces recombination on chromosome arms\; distribution of crossovers in Rec-1 approximates physical map.  ES1, ME3. NA1.  [Rose and Baillie 1979\; Zetka and Rose 1995\;  KR]"	
"ric-1"	"III"	-0.691172	"[C.elegansII] e239 : (pka lar-5), resistant to cholinesterase inhibitors.  OA2: n1602 (pka osm-10,specifically defective in osmotic avoidance, normal chemotaxis), n1337 (pka ric-5)[Bargmann et al.1990\; Nguyen et al. 1995\; CX\; RM]"	
"ric-4"	"V"	2.1091	"[C.elegansII] md1088 :  Unc, slow movement, great difficulty backing, small, slow growing, resistant to cholinesterase inhibitors OA2: md1136, md1192. Cloned: encodes predicted protein with similarity to SNAP-25 (57\% identity to Drosophila SNAP-25)[Nguyen et al. 1995\; RM\; TY]"	
"rol-1"	"II"	7.26897	"[C.elegansII] e91 : adults left-handed rollers. ES3 (adult) ME1. OA1: sc22ts (left roller, slightly dumpy adult at 25C). [Cox et al. 1980]"	
"rol-3"	"V"	1.3138	"[C.elegansII] e754 : adults left-handed rollers. ES3 (adult) ME1. OA1 (viable): e202.Also lethal alleles (high forward mutation rate), OA>10: s126, s422 (pka let-333), s742gri, s833,s1040ts (lethality suppressed by srl-1 orsrl-2), s1408, s1519 etc.  Lethal arrest for most alleles early to mid larval.  [Cox et al. 1980\; Barbazuk et al. 1994\; BC]"	
"rol-4"	"V"	4.33187	"[C.elegansII] sc8 : adults and L4 larvae left-handed rollers. ES3 (adult) ME2. OA2: b238ts (at 25C rolls only in adult, WT at 16C). [Cox et al. 1980]"	
"rol-6"	"II"	0.813592	"[C.elegansII] e187 : adults, L3 and L4 larvae right-handed rollers. ES3 (adults, late larvae). ME0. Similar phenotype in e187\/Df. OA6 (recessive): sc90, n1177 (both have no phenotype alone but fail to complement e187). Also intragenic revertants e187n1270 (WT) etc.\;  null phenotype probably wildtype. Also neomorphic allele:su1006dm (both su1006 and su1006\/+ severe right-handed rollers in L3, L4, adult\; phenotype more extreme than e187).su1006 widely used as dominant transformation marker (ES3\; ME1). Cloned:  encodes collagen, sqt-1 family. [Cox et al. 1980\; Kramer et al. 1990\; Mello etal. 1992\; Park and Kramer 1994\; CH]"	
"rol-8"	"II"	0.90495	"[C.elegansII] sc15 : adults left-handed rollers. OA1: sc102. [Kusch and Edgar 1986\; BE]"	
"rol-9"	"V"	25.1753	"[C.elegansII] sc148 : adults strong right-handed roller, late larvae weak roller.  sc148\/+ sometimes very weak roller.  ES3 (adult).  OA1: sc149. [BE]"	
"rrs-1"	"V"	10.8344	"[C.elegansII] Structural locus for 5S RNA and SL1. Approximately 110 tandem copies of 1 kb sequence coding for 5S RNA, alternating with sequence encoding SL1.  e2482 (pka zen-1) and w1 are deletions of this locus leading to embryonic lethality (arrest at 200-300 cells, no compaction) , orto L1 lethality if SL1 supplied transgenically. [Nelson and Honda 1986\; Krause and Hirsh 1987\; JR]"	
"sdc-1"	"X"	23.4741	"[C.elegansII] n485mat : (pka egl-16) very variable bloating\; some animals form bag-of-worms (Type A) or explode at vulva\; abnormal vulval morphology\; some masculinization of XX animals (especially at 15C). Weaker phenotype if mother n485\/+. ES2\/3 (adult). ME2. XX progeny of n485\/Df mothers have incompletely penetrant partially male (Tra) phenotype. OA>5\; e2426, n485, y4, y67ts (30\% masc. at 20C), etc. Most alleles have apparent dosage compensation defects, variable masculinizing effects. Cloned: encodes 1203 aa protein with 7 N-term zinc fingers. [Villeneuve and Meyer 1990\; Nonet and Meyer 1991\; TY]"	
"sdc-2"	"X"	4.73609	"[C.elegansII] y15 : XX animals inviable and masculinized, XO animals WT.  No maternal rescue. ES3 (XX)\; ME3.OA>20: y46, y74, y55 (weaker, Egl or Tra phenotypes). ???Cloned: 9.2 kb transcript, encodes predicted 2962 protein (344 kD), highly charged. [Nusbaum and Meyer 1989\; TY]"	
"sdc-3"	"V"	6.94017	"[C.elegansII] y126mat : deletion null, XX animals inviable if mother homozygous\; rare escapers dumpy hermaphrodite\; cryptic masculinization\; XO phenotype WT.OA>10: y122, y127, y143 (similar)\; also sdc-3 (Tra)alleles: y52 (XX viable, masculinized), y137 (weaker)\; also sdc-3(Dpy) alleles: y100 (XX inviable or dumpy,no masculinization), y128 etc. Cloned: 7kb transcript present in embryo, L1, L2\; encodes 2150 aa protein, possible ATP-binding site (affected in Tra mutations), 2 C-term zinc fingers (affected in Dpy mutations). [DeLong et al. 1993\; Klein and Meyer 1993\; TY]"	
"sel-1"	"V"	4.44026	"[C.elegansII] e1948 : pka sup-25, recessive suppressor of lin-12h ypomorph(n676n930ts), and partial suppressor of glp-1 hypomorph\; no effect on lin-12 amorph\; no phenotype alone. No suppression of lin-3, egl-15, etc.OA4: ar23, ar29, ar73, ar77. Cloned: encodes predicted 650 aa protein with signal sequence.  [Sundaram and Greenwald 1993\; GS]"	
"sel-2"	"III"	-3.02483	"[C.elegansII] n655 : interacts with lin-12(n302sd). [GS]"	
"sel-4"	"II"	-16.4922	"[C.elegansII] n1259 : suppressor of lin-12 hypermorph (n302sd). [JT\; MT]"	
"sel-5"	"III"	-3.38783	"[C.elegansII] n1524 : suppressor of lin-12 hypermorphs (n302sd, etc.).  Mosaic analysis indicates focus in VU not AC. [JT\; MT]"	
"sel-6"	"V"	20.3807	"[C.elegansII] n1256 : suppressor of lin-12 hypermorph (n302sd). [JT\; MT]"	
"sel-7"	"X"	17.3389	"[C.elegansII] n1253 : suppressor of lin-12 hypermorph (n302sd)[JT\; MT]"	
"sel-9"	"V"	1.33837	"[C.elegansII] ar22 : suppressor of hypomophic lin-12 allele, also partial suppressor of glp-1 hypomorph. No effect on lin-12 amorph. No phenotype alone. Probable gf mutation. OA1: ar26. [Sundaram and Greenwald 1993\; GS]"	
"sel-10"	"V"	5.75	"[C.elegansII] ar41 : recessive suppressor of lin-12 hypomorph allele, and partial suppressor of glp-1 hypomorph, some effect on lin-12 amorph\; properties affected by extragenic modifier. No phenotype alone.OA1 (ar28) [Sundaram and Greenwald 1993\; GS]"	
"sel-11"	"V"	3.22945	"[C.elegansII] ar39 : recessive suppressor of lin-12 hypomorph, and partial suppressor of glp-1 hypomorph\; no effect on lin-12 amorph\; no phenotype alone\; probable gf mutation. OA1: ar84. [Sundaram and Greenwald 1993\; GS]"	
"sel-12"	"X"	-18.8529	"[C.elegansII] ar131 : (pka sum-1) recessive suppressor of Muv phenotype of lin-12 hypermorph n950\; impenetrant Egl in lin-12(+) background.OA3: ar133, ar171 (100\% Egl, ar171\/Df similar,W225op). Cloned: encodes predicted 467 aa protein, 9 TM domains\; related to human presenilin genes(S182) and to SPE-4. [Levitan and Greenwald 1995\; GS]"	
"sem-1"	"X"	14.2203	"[C.elegansII] n1382 : Egl, hermaphrodite sex muscles fail to divide.ME3.  [MT\; NH]"	
"sem-2"	"I"	-0.289841	"[C.elegansII] n1343mut : Egl, hermaphrodite sex muscles adopt body wallmuscle fate.ME3. OA5: some alleles have additional phenotypes ,4 are embryonic lethal, arrest 1.5-fold with bloated head.  [MT\; NH\; RW]"	
"sem-3"	"IV"	4.91904	"[C.elegansII] n1655 : Egl (5-HT resistant), hermaphrodite sex muscles show subtle positioning defects. ME3. OA>3: n1905, s1734 (pka let-654, hemizygote mid larval lethal), [Clark and Baillie 1992\; BC\; NH]"	
"sem-4"	"I"	1.66165	"[C.elegansII] n1378 : Egl, hermaphrodite sex muscles fail to differentiate\; additional axon and lineage defects. ME0 (severe Mab), HME3.  OA3: h769, n2087, n1971 (stronger allele, two mesodermal and six neuronal cell types pleiotropically affected\; 2 additional touch cells formed in tail), etc.  Cloned: encodes predicted protein with 6 C2H2 zincfinger motifs. [Desai et al. 1988\; Mitani et al. 1993\; MT\; NH\; TU]"	
"sem-5"	"X"	-0.823823	"[C.elegansII] n2030 : vulvaless, hermaphrodite sex muscles show subtle positioning defect, Soc (suppressor of clr-1),impenetrant Mel (rod-like larval lethal)\; pleiotropic effects on migration, vulval induction etc.   ME0.  OA5: strong alleles n1619, n2019\; weaker alleles n1781, n2195 (Soc, weak Egl, ME3),n1619, n1779 (synergizes with alleles of unc-71,unc-73, egl-15, egl-17,to give stronger Sem defect). Cloned: encodes predicted SH3-SH2-SH3 protein with 60\% identity to human GRB2, functional equivalence. [Clark et al. 1992\; Stern et al. 1993\; DeVore et al.1995\; MT\; NH]"	
"shv-1"	"II"	1.6328	"[C.elegansII] oz128sd : homozygous hermaphrodite sometimes sterile and often contains a multiple-armed somatic gonad with 3 or 4 distal tip cells. Male appears normal.  Probable gf allele. NA1 (gf).  Also recessive intragenic revertants:oz128oz157 (hermaphrodite-sterile with defect in germ line proliferation\; partial loss-of-function), etc. [BS]"	
"skn-1"	"IV"	2.14335	"[C.elegansII] zu67mat : maternal effect embryonic lethal, extra internal hypodermal cells, fails to produce pharynx and intestine\; EMS adopts P2-like fate(MS more affected than E).  OA>5: or12, or13 etc. Cloned: encodes predicted transcription factor. Antibody stains early nuclei, differential localization to EMS, not detectable beyond 12-cell stage. [Bowerman et al. 1992, 1993\; EU\; JJ]"	
"sli-1"	"X"	-19.107	"[C.elegansII] sy143 : suppressor of vulvaless phenotype of let-23 hypomorph\; other let-23 defects suppressed, but not sterility\; multivulva phenotype in combination with unc-101\; low penetrance head morphology defect in let-23(+) background. sy143\/Df similar.  OA>10: sy263 (weaker), sy129 etc. Cloned: encodes homolog of mammalian oncogene c-cbl (55\% identity over 390 aa, containing RING finger motif.  sy129 missense. [Jongeward et al. 1995\; Yoon et al. 1995\; PS]"	
"sma-1"	"V"	3.45274	"[C.elegansII] e30 : short round-headed, especially in early larvae\; adults have slight rolling tendency. ES3. OA>10: e656, e2075(pka sma-7, ME2), e1160, e2090, n504, etc. Cloned: encodes predicted cytoskeletal protein. [Brenner 1974\; AZ]"	
"sma-2"	"III"	-0.061683	"[C.elegansII] e502 : short, somewhat dumpy\; males have crumpled spicules, abnormal rays\; synthetic lethal with some morphological mutants\; mosaic analysis indicates cell autonomous action.  Similar to Sma-3, Sma-4, Daf-4. ES3 (adult) ME0. OA>5: e172, e297, e1491(weaker), s262 (induced on eT1)  etc. Cloned: encodes DWARFIN [Baird et al. 1991\; LT\; PB]"	
"sma-3"	"III"	-0.906668	"[C.elegansII] e491 : short, somewhat dumpy\; males have crumpled spicules, abnormal rays. Similar to Sma-2, Sma-4, Daf-4ES3 (adult), ME0. OA2: e637, e958. Cloned: encodes DWARFIN. [Baird et al. 1991\; LT\; PB]"	
"sma-4"	"III"	-1.43	"[C.elegansII] e729 : short non-dumpy\; males have crumpled spicules, abnormal rays. ES3 (adult) ME0. OA1 (e805). [Brenner 1974\; LT\; PB]"	
"sma-5"	"X"	6.76998	"[C.elegansII] n678 : very small adult, slow-growing\; small in L1 and L2. ES3 NA1. [MT]"	
"sma-6"	"II"	-0.399791	"[C.elegansII] e1482 : short adult and late larvae. e1482\/Df similar. ES2 ME3. NA1. [CB]"	
"sma-8"	"V"	3.20491	"[C.elegansII] sma-8(e2111dm) : short blunt head\; e2111\/+ similar phenotype. ES3. OA1: n716sd (recessive lethal). [Park and Horvitz 1986\; Chen et al. 1992\; PD]"	
"smg-1"	"I"	1.49885	"[C.elegansII] e1228 : adult male has swollen bursa.ES3 (adult male) ME1. Adult hermaphrodite has protruding vulva. ES2. Recessive suppressor of unc-54(r293), tra-2(e1209), etc.  unc-54 nonsense RNAs accumulate.OA>10: e1233, e2134spo (similar phenotypes), ma127, ma131, r861, r913spo, etc. Cloned: 7.8 kb transcript, encodes predicted protein with some kinase similarity in C-term. [Hodgkin et al. 1989\; Pulak and Anderson 1993\; TR]"	
"smg-2"	"I"	-17.8838	"[C.elegansII] e2008 : adult male has swollen bursa, ES3 ME1. Adult hermaphrodite has protruding vulva ES2. Recessive suppressor of unc-54(r293), tra-2(e1209), etc.  unc-54 nonsense RNAs accumulate. OA>10: e2423, ma114, ma122, r863, r920::Tc4,r908 (deletion), etc. Cloned: encodes predicted protein with 36-69\% similarity to yeast UPF1. [Hodgkin et al. 1989\; Pulak and Anderson 1993\; TR]"	
"smg-3"	"IV"	3.18092	"[C.elegansII] ma117 : adult male has swollen bursa, adult hermaphrodite has protruding vulva.  ME1. Recessive suppressor of unc-54(r293), tra-2(e1209), etc.\; suppression reduced by maternal rescue.  unc-54 nonsense RNAs accumulate.OA>3: ma115, r867 etc. [Hodgkin et al. 1989\; Pulak and Anderson 1993\; TR]"	
"smg-4"	"V"	2.19865	"[C.elegansII] ma116 : adult male has swollen bursa, adult hermaphrodite has protruding vulva.  ME1. Recessive suppressor of unc-54(r293),tra-2(e1209), etc.\; suppression reduced bymaternal rescue.  unc-54 nonsense RNAs accumulate. OA3: r1181, e2615psu, e2616psu. Cloned: YAC and phage rescue. [Hodgkin et al. 1989\; Pulak and Anderson 1993\; CB\; TR]"	
"smg-5"	"I"	1.30212	"[C.elegansII] r860 : adult male has swollen bursa, adult hermaphrodite has protruding vulva.  ME1. Recessive suppressor of unc-54(r293), tra-2(e1209), etc.  unc-54 nonsense RNAs accumulate.OA1: r919::Tc1. Cloned: encodes 549 aa novel protein\; 56 kD protein detected by western.  In vitro and in vivo, SMG-5 interacts with SMG-7. [Hodgkin et al. 1989\; Pulak and Anderson 1993\; TR]"	
"smg-6"	"III"	-16.6633	"[C.elegansII] r896 : adult male has swollen bursa, adult hermaphrodite has protruding vulva.  ME1. Recessive suppressor of unc-54(r293),tra-2(e1209), etc.\; suppression reduced by maternal rescue.  unc-54 nonsense RNAs accumulate.OA9: r886 (similar), r1059 (embryonic lethal), r1062 (early larval lethal), r1014 (late larval lethal). [Hodgkin et al. 1989\; Pulak and Anderson 1993\; TR]"	
"smg-7"	"IV"	3.20537	"[C.elegansII] r1131::Tc1 : suppresses unc-54(r293), tra-2(e1209), dpy-5(e61). unc-54 nonsense mRNAs accumulate. Hermaphrodites are Pvul, males are Mab. Cloned: encodes predicted 53 kD protein with 3 tetratricopeptide repeats\; 54 kD protein detected by western.  In vitro and in vivo, SMG-7interacts with SMG-5. [TR]"	
"smu-1"	"I"	19.431	"[C.elegansII] mn415 : suppresses Mec (touch insensitive) and Dyf (dye-filling defective) phenes of mec-8(u218ts), Mec phene of mec-8(mn472ts), Dyf phene of most mec-8 alleles, variable cold-sensitive arrest of mec-8(u74) and mec-8(mn463), Unc phene of unc-52(e669su250ts) and synthetic lethality of mec-8(u218ts)\; unc-52(e669su250ts). Essentially WT phenotype alone.  OA2: mn417, mn433 [Lundquist and Herman 1994\; SP]"	
"smu-2"	"II"	-6.24002	"[C.elegansII] mn416 : suppresses Mec (touch insensitive) and Dyf (dye-filling defective) phenes of mec-8(u218ts), Mec phene of mec-8(mn472ts), Dyf phene of most mec-8 alleles, variable cold-sensitive arrest of mec-8(u74) and mec-8(mn463), Unc phene of unc-52(e669su250ts) and synthetic lethality of mec-8(u218ts)\; unc-52(e669su250ts). Essentially WT alone. [Lundquist and Herman 1994\; SP]"	
"snb-1"	"V"	0.193058	"[C.elegansII] md247 : lethargic, jerky, Ric, accumulates acetylcholine. Cloned: encodes synaptobrevin homolog (67\%identity to human VAMP-1)  [NM\; RM]"	
"snt-1"	"II"	0.119906	"[C.elegansII] md125 : (pka ric-2) uncoordinated, slight shrinker, small, slow-growing, resistant to cholinesterase inhibitors\; some  pumping and defecation defects.  OA2: ad596 (pka unc-121, Unc, worse when starved\; ME2), n2665. Cloned: encodes synaptotagmin (54\% identity to mammalian synaptotagmin) [Nonet et al. 1993\; Nguyen et al. 1995\; NM\; RM]"	
"soc-2"	"IV"	1.6	"[C.elegansII] n1774 : suppressor of clr-1.  OA1. [DeVore et al. 1995\; NH]"	
"sog-1"	"I"	1.95548	"[C.elegansII] q305 : recessive suppressor of ts glp-1 alleles q224 and q231, suppresses both germ-line and embryonic defects. Does not suppress stronger glp-1 alleles. No phenotype alone. Other alleles exhibit complex non-allelic non-complementation with mutations of other sog genes. OA1: q298 [Maine and Kimble 1993\; EL]"	
"sog-2"	"II"	2.40741	"[C.elegansII] q299 : recessive suppressor of ts glp-1 alleles q224 and q231, suppresses both germ-line and embryonic defects. Does not suppress stronger glp-1 alleles. No phenotype alone. [Maine and Kimble 1993\; EL]"	
"sog-3"	"IV"	3.14904	"[C.elegansII] q294 : recessive suppressor of ts glp-1 alleles q224 and q231, suppresses both germ-line and embryonic defects. Does not suppress stronger glp-1 alleles. No phenotype alone. [Maine and Kimble 1993\; EL]"	
"sog-4"	"V"	1.55323	"[C.elegansII] q301 : recessive suppressor of ts glp-1 alleles q224 and q231, suppresses both germ-line and embryonic defects. Does not suppress stronger glp-1 alleles. No phenotype alone.  OA1: q304[Maine and Kimble 1993\; EL]"	
"sog-5"	"X"	-5.26076	"[C.elegansII] q297 : recessive suppressor of ts glp-1 alleles q224 and q231, suppresses both germ-line and embryonic defects. Does not suppress stronger glp-1 alleles. No phenotype alone. [Maine and Kimble 1993\; EL]"	
"sog-6"	"IV"	4.35684	"[C.elegansII] q300 : recessive suppressor of ts glp-1 alleles q224 and q231, suppresses both germ-line and embryonic defects. Does not suppress stronger glp-1 alleles. No phenotype alone. OA1: q306[Maine and Kimble 1993\; EL]"	
"sog-10"	"III"	-2.54277	"[C.elegansII] q162 : suppressor of germ-line defect of some weak glp-1 alleles. Cold-sensitive Fog phenotype alone, q162\/Df stronger Fog. [Maine and Kimble 1993\; EL]"	
"spe-1"	"II"	0.405796	"[C.elegansII] mn47 : hermaphrodites and males produce aberrant spermatids which fail to activate into spermatozoa. Spermatids exhibit unusual and rapid cytoplasmic movement. ES2 (adult). NA1. [Sigurdson et al. 1984]"	
"spe-3"	"II"	-0.900181	"[C.elegansII] mn230pat : hermaphrodites lay self-fertilized eggs that do not hatch but eggs are viable if cross-fertilized by mn230 sperm from mn230\/+ males. (Same Spe phenotype as spe-2, but non-Sqv).ES3 (progeny). NA1. [Sigurdson et al. 1984]"	
"spe-4"	"I"	2.05	"[C.elegansII] hc78 : hermaphrodites and males produce primary spermatocytes that contain 4 haploid nuclei\; males retain these spermatocytes while hermaphrodites resorb them when oogenesis begins. Self-fertility 0\%. Similar phenotype in hc78\/Df. Fibrous body-membranous organelle formation disrupted.ES2 (adult). OA2: hc81, q347 (deletion null). Cloned: 1.3 kb transcript, spermatogenesis specific\; encodes  predicted 465 aa protein, probable 7 TM domains, similarity to human S182(Alzheimer's associated) and SEL-12.  SPE-4 segregates to spermatids. [L'Hernault and Arduengo 1992\; SL]"	
"spe-5"	"I"	-0.288923	"[C.elegansII] hc93 : hermaphrodites and males produce primary spermatocytes that occasionally begin first meiotic division but do not differentiate further\; abnormal fibrous body-membranous organelle complex. Self-fertility <1\%. ES2 (adult). OA3: hc110, etc., all slightly leaky, cs. Cloned: encodes predicted 25 kD protein, 4 TM domains, large hydrophilic domain. [L'Hernault et al. 1988\; SL]"	
"spe-6"	"III"	10.0974	"[C.elegansII] hc49 : hermaphrodites and males produce primary spermatocytes that do not differentiate further\; no division, eventual degeneration\; MSP fails to assemble into fibrous body-membranous organelle. ES2 (adult). OA3 : hc92, hc143, also non-allelic failure to complement eDf19. [Varkey et al. 1993\; BA\; HU]"	
"spe-8"	"I"	-17.383	"[C.elegansII] hc40 : hermaphrodites produce nonfunctional nonmotile sperm with uniformly aberrant pseudopods\; male sperm normal. Self-fertility < 1\% (16C or 25C). ES2 (adult). OA5: hc50. hc53 etc. [L'Hernault et al. 1988\; Shakes and Ward 1989a\; BA]"	
"spe-9"	"I"	8.5	"[C.elegansII] hc52ts : hermaphrodites and males grown at 25C produce motile sperm that are fertilization defective. Self-fertility < 1\% (25C) 100\% (16C). ES2 (adult). OA3: hc88ts,also nonconditional alleles. [L'Hernault et al. 1988\; SL]"	
"spe-10"	"V"	2.68619	"[C.elegansII] hc104ts : hermaphrodites and males produce nonfunctional but motile sperm with short pseudopods\; severe defects in fibrous body-membranous organelle. ES2 (adult). NA1. [Shakes and Ward 1989b\; BA\; DS]"	
"spe-11"	"I"	-0.104303	"[C.elegansII] hc77ts : hermaphrodites and males grown at 25C produce motile sperm that are fertilize oocytes leading to abnormal early development.defective. Self-fertility 3\% (25C) 100\% (16C). Similar phenotype in hc77\/Df. ES2 (adult). OA3: hc90 (nonconditional sterile). Cloned: encodes 299 aa novel protein, highly charged and hydrophilic\; transcript only in sperm, but forced expression in oocyte can rescue Spe phenotype.  SPE-11 in perinuclear halo of mature sperm. [Hill et al. 1989\; SS]"	
"spe-12"	"I"	2.5338	"[C.elegansII] hc76 : hermaphrodites produce nonfunctional sperm fertilization defective\; males are fertile. Similar phenotype in hc76\/Df. Spermatids activated by ionophores\; arrest as spiky intermediates after protease activation. Self-fertility <1\% (16C or 25C). ES2 (adult). NA1. Cloned: transcript only in spermatogenic germ line, predicted protein novel? [L'Hernault et al. 1988\; Shakes and Ward 1989a\; BA]"	
"spe-13"	"I"	-20	"[C.elegansII] hc137ts : at 25C, spermatids can activate to form crawling sperm, unable to fertilize. Low hermaphrodite self-fertility at 15C.  NA1. [L'Hernault et al. 1988\; SL]"	
"spe-15"	"I"	-15.9774	"[C.elegansII] hc75ts : at 25C, spermatids can activate to form crawling sperm, unable to fertilize. Low hermaphrodite self-fertility at 15C.  NA1. [L'Hernault et al. 1988\; SL]"	
"spe-16"	"III"	8.22783	"[C.elegansII] hc54ts : at 25C, hermaphrodites make non-functional sperm with WT cytology. [SL]"	
"spe-26"	"IV"	4.62	"[C.elegansII] hc138 : accumulates defective spermatocytes\; pleiotropic effects in increasing lifespan, thermotolerance, UV resistance. OA5: hc139, hc140, it112, it118, hc107ts( Spe, non-Age).5\/6 alleles ts. Cloned: encodes 570 aa protein containing 5 tandem 50 aa scruin\/kelch repeats, possible actin-binding domains. [Van Voorhies 1992\; Varkey et al. 1995\; BA\; HU\; KK]"	
"spe-27"	"IV"	2.50803	"[C.elegansII] it132 : ts, hermaphrodites produce nonfunctionalsperm, males are fertile.  Hypomorphic allele.OA>3: some alleles probably null. Cloned: transcript only in spermatogenic germ line, encodes novel predicted protein. [BA]"	
"spe-29"	"IV"	4.47572	"[C.elegansII] it127 : leaky, hermaphrodites produce nonfunctional sperm, almost self-sterile (brood 4 - 10 at 20C, 1 - 2 at16C or 25C)\; males are fertile.  it127\/Df similar.  NA1. [BA]"	
"sqt-1"	"II"	3.38472	"[C.elegansII] sclsd : homozygotes short, dumpyish in adult and L4\; roll in L3\; scl\/+ non-dumpy right-handed rollers in adult, L4,L3. ES3 ME1. OA>10 (dominant): su1005, e1584 (resemble scl), e1350 (recessive dumpy) etc.). Also recessive alleles e.g. sc13 (pka rol-5,  adults L3 and L4 larvae left-handed rollers. ES3 (adult, late larvae)), sc101 (long), sc33ts (at 25C rolls only in adult at 16C wildtype) etc. Complex complementation patterns. Null phenotype probably wildtype. Cloned: encodes 32 kD collagen, sqt-1 family includes rol-6\; expressed each larval stage, 4 - 2.5 hr pre-lethargus. [Kramer et al. 1988\; Park and Kramer 1994\; CH\; IA]"	
"sqt-2"	"II"	-18.2925	"[C.elegansII] sc3sd : homozygotes slightly dumpyish in adult late larvae\; roll in L3\; sc3\/+ non-dumpy right-handed roller in adult, L4, L3. ES3 (adult). OA6: sc14 (stronger phenotype than sc3), e1486, sc108 etc. [Kusch and Edgar 1986]"	
"sqt-3"	"V"	3.98027	"[C.elegansII] sc63ts,sd : homozygotes at 25C are non-roller dumpy, heterozygotes sc63\/+ are non-dumpy left-handed roller in adult\; high penetrance deformed tail at 25C. ES3 ME0 (25C). At 15C slightly dumpy. OA3: sc80ts (resembles sc63), e24sd,ts (pka dpy-15, dumpy inviable at 25C, e24\/+ dumpy at 25C, sometimes Lon at15C), sc42 (recessive left roller), e2117ts (extreme dumpy early larval lethal at 25C). Cloned: encodes 295 aa collagen (pka col-1), dpy-13 family\;  mutations all missense\; expressed at each larval stage, 4 - 2.5 hours before lethargus. [Kramer et al. 1982\; Keyl et al. 1994\; IA]"	
"sqv-1"	"IV"	3.73559	"[C.elegansII] n2820 :  morphology of L4 vulva abnormal (invagination considerably reduced)\; hermaphrodites  almost self-sterile. OA5: n2819, n2828, n2848, n2849, n2824 (all self-sterile?). [MT]"	
"sqv-2"	"II"	-6	"[C.elegansII] n2826 : morphology of L4 vulva abnormal (invagination considerably reduced)\; hermaphrodites self-sterile. OA4: n2821 (somewhat fertile), n3037, n3038,n2826, n2821. [MT]"	
"sqv-3"	"III"	0.761043	"[C.elegansII] n2823 : morphology of L4 vulva abnormal(invagination considerablyreduced)\; hermaphrodites self-sterile. OA2: n2841, n2842. Cloned: encodes predicted protein with similarity to beta 1,4 galactosyltransferase. [MT]"	
"sqv-4"	"V"	2.71409	"[C.elegansII] n2840 : morphology of L4 vulva abnormal (invagination considerably reduced)\; hermaphrodites self-sterile OA1: n2827. [MT]"	
"sqv-5"	"I"	6.33937	"[C.elegansII] n3039 : morphology of L4 vulva abnormal (invagination considerably reduced)\; hermaphrodites self-sterile. [MT]"	
"sqv-6"	"V"	0.64718	"[C.elegansII] n2845 : morphology of L4 vulva abnormal (invagination considerably reduced)\; hermaphrodites self-sterile. [MT]"	
"sqv-7"	"II"	0.199023	"[C.elegansII] n2844 : morphology of L4 vulva abnormal (invagination considerably reduced)\; hermaphrodites self-sterile. OA1: n2839 (somewhat fertile). [MT]"	
"sqv-8"	"II"	1.59938	"[C.elegansII] mn63pat : hermaphrodites lay self-fertilized eggs that do not hatch but eggs are viable if cross-fertilized by mn63 sperm from mn63\/+ males.  Also Sqv (squashed vulva) phenotype, morphology of L4 vulva abnormal (invagination considerably reduced). OA>5:  n2843, n2847, n2850, n2851, n3036, n2822, n2825 (somewhat fertile). Cloned: encodes predicted novel protein\;possible TM domain. [Sigurdson et al. 1984\; MT]"	
"srf-1"	"II"	4.31771	"[C.elegansII] yj1 : adult cuticle fails to bind adult-specific antiserum.  Gross morphology wildtype. [Politz et al. 1990\; AT]"	
"srf-2"	"I"	5.28521	"[C.elegansII] yj262 : increased binding of anti-cuticle antiserum, ectopic lectin WGA binding, no labelling with L1-specific mAb M38.  Gross morphology WT.OA>20: yj133, yj422, ct104, ct117, dv1, dv2, dv37etc.  All alleles recessive. [Hemmer et al. 1991\; Link et al. 1992\; AT\; CL]"	
"srf-3"	"IV"	6.37208	"[C.elegansII] yj10 : increased binding of anti-cuticle antiserum, ectopic WGA lectin binding, no labelling with L1-specific mAb M38.  Gross morphology WT.  Fragile cuticle, increased drug permeability, reduced SDS resistance of dauers.  OA1: ct107[Hemmer et al. 1991\; Link et al. 1992\; AT\; CL]"	
"srf-4"	"V"	23.9823	"[C.elegansII] ct109 : altered cuticle labelling, ectopic WGA lectin binding, pleiotropic defects: Unc, Egl, Mab, Mig (DTC), variable neuronal abnormalities, SDS-sensitive dauers\; enhance lin-12(gf).  OA7: ct113, dv11, dv39 etc. [Link et al. 1992\; CL]"	
"srf-5"	"X"	12.5498	"[C.elegansII] ct115 : ectopic surface binding of lectins SBA, WGA.  OA5: ct114, dv18, dv32, dv40 etc. [Link et al. 1992\; CL]"	
"srf-6"	"II"	0.116876	"[C.elegansII] yj13 : all larval stages (but not adult) label with L1-specific mAbs M37, M38.  Gross phenotype WT.  See also daf-1,4,7,8,11,14. OA4: yj41, yj43, yj5, yj15. [AT\; DR]"	
"srf-8"	"V"	3.08717	"[C.elegansII] dv38 : altered cuticle labelling, ectopic WGA lectin binding, pleiotropic defects: Unc, Egl, Mab, Mig(DTC), variable neuronal abnormalities,SDS-sensitive dauers\; enhance lin-12(gf),[Link et al. 1992\; CL]"	
"srf-9"	"V"	1.41682	"[C.elegansII] dv4 :  altered cuticle labelling, ectopic WGA lectin binding, pleiotropic defects: Unc, Egl, Mab, Mig(DTC), variable neuronal abnormalities, SDS-sensitive dauers\; enhance lin-12(gf),OA1: dv16. [Link et al. 1992\; CL]"	
"stu-2"	"II"	2.01831	"[C.elegansII] e2297spo :  thin, sterile, uncoordinated. Males similar\; testis thin but well-formed, contains sperm. No rays or fan, spicules rudimentary. ES3. NA1. [CB]"	
"stu-3"	"V"	25.0973	"[C.elegansII] q265 : uncoordinated, sterile, vulvaless. [BS]"	
"stu-4"	"I"	-4.41641	"[C.elegansII] e2406ts : sterile unc, extensive failures of postembryonic cell division at 25C, many polyploid nuclei, probable defect in karyokinesis. Hermaphrodites and males viable and fertile at 15C. [CB]"	
"stu-6"	"X"	5.25005	"[C.elegansII] e2408 : sterile and uncoordinated but not defective in cell division: small, variably dumpy, often second vulval protrusion posteriorly. Abnormal gonad arms, abnormal oocytes, ventral cord has abnormal positioning of nuclei and commissures, cord sometimes detached from hypodermal ridge. [CB]"	
"sud-1"	"II"	0.926168	"[C.elegansII] Mutation leads to embryonic lethality, high cell number\; possible failure to repress cell cycle at end of proliferation phase. [GE]"	
"sup-1"	"III"	11.735	"[C.elegansII] e995dm : dominant allele-specific suppressor of unc-17(e245)\; does not suppress unc-17(e876)\; no phenotype alone. ES3 in presence of e245 ME3. OA>5: e996xri, e1827, e1955 etc. (all similar). [CB\; RM]"	
"sup-2"	"X"	1.44118	"[C.elegansII] e997dm : dominant suppressor of unc-17(e245),does not suppress unc-17(e876), no phenotype alone. ES3 in presence of e245 ME3.  Weaker suppressor than sup-1. NA1. [CB\; RM]"	
"sup-6"	"II"	12.1451	"[C.elegansII] st19dm : dominant suppressor of unc-13(e309)\; recessive lethal\; also suppresses certain daf mutations\; does not suppress amber or ochre alleles of unc-54. ES3. [PD\; RW]"	
"sup-7"	"X"	-2.92323	"[C.elegansII] st5sd : strong amber suppressor, partially or completely suppresses amber alleles of more than forty different genes\; slow growing or sterile below 22C, grows best at 23C\; suppression strongest at low temperature\; otherwise no gross phenotype alone\; alteration in tRNATrp anticodon. ES3 in presence of unc-13(e450) etc. ME2. OA5 all identical to st5. Corresponds to rtw-2. [Waterston 1981\; Wills et al. 1983]"	
"sup-8"	"V"	0.001961	"[C.elegansII] e1563dm,uvi : dominant suppressor of unc-17(e245)\; no phenotype alone. ES3 in presence of e245. NA1. [CB]"	
"sup-9"	"II"	-11.9075	"[C.elegansII] n180 : recessive suppressor of unc-93(e1500) no phenotype alone\; probably null allele. ES3 in presence of e1500 ME3. OA>20(lf):n180spo, n192uvi, n186, n350  (all resemble n180). Also neomorphic dominant allele n1550sd(severe rubber-band, almost sterile, inviable\;n1550\/+ strong \"rubber-band\" Unc-93 phenotype.  Muscle activation defective (flaccid, long)). Also dominant negative suppressor alleles n1435, n242 (semidominant suppressors of sup-10(n983). [Greenwald and Horvitz 1980, Levin & Horvitz 1993]"	
"sup-10"	"X"	24.1207	"[C.elegansII] n183 : recessive suppressor of unc-93(e1500) no phenotype alone\; probably null allele. ES3 in presence of e1500, ME3. OA>20(lf):n181spo, n245gri, n184 (large viable deletion, also removes mlc-1, nhr-1), n185, n221, n1034 etc.Also neomorphic dominant allele n983dm(uncoordinated \"rubber-band\" Unc-93 paralysis muscle activation defective (flaccid, long)\; suppressed by intragenic revertants, unc-93 null alleles etc.). Cloned: sequence predicts 332 aa protein, possible signal sequence, TM domain. [Greenwald and Horvitz 1980, Levin & Horvitz 1993\; MT]"	
"sup-11"	"I"	-5.81337	"[C.elegansII] n403sd : dominant suppressor of unc-93(e1500) recessive small scrawny slow growing phenotype. ES3. OA9 (dominant): n401, n402,n404, n406 etc. (all resemble n403). Also alleles derived from n403 e.g. n403n406(recessive suppressor of unc-93(e1500), no phenotype alone).  OA7 (recessive). Also putative null alleles derived from n403 e.g. n403n682 (no suppressive effect, recessive lethal, late embryo arrest).OA3: n403n681amb (partly suppressed by sup-5, L1 lethal). [Greenwald and Horvitz 1982\; MT]"	
"sup-12"	"X"	-8.44115	"[C.elegansII] st89 : recessive suppressor of unc-60(e677) and other unc-60 alleles\; (e723, e890)\;alone, abnormal gonad and minor changes in body wall muscle ultrastructure ES3 in presence of e677. OA>10: st86 (suppresses lethal allele unc-60(s1586) to viable ts sterile phenotype), etc. [Francis and Waterston 1985\; BC]"	
"sup-13"	"III"	0.009513	"[C.elegansII] st210 : strong recessive suppressor of unc-78(e1217) and at least two other unc-78 alleles (e1221, st43)\; no phenotype alone. ES3 in presence of e1217. [RW]."	
"sup-17"	"I"	3.04142	"[C.elegansII] n316 : allele and lineage non-specific suppressor of lin-12 dominant mutations,weakly dominant\; phenotype alone is recessive Dpy, recessive Egl\; abnormal vulval cell lineages\; male tail abnormal\; Egl and Dpy phenotypes stronger at 25C. ES2 ME0. Similar degree of suppression of lin-12(dom) in nDf24\/+ and n316\/+\; also n316\/nDf24 is maternal effect lethal. OA>5: n1260 (weakly sd,ts (15C phenotype non-Dpy non-Egl very weak suppressor ME3\; 25C phenotype similar to n316), n1258, n1306 etc. [Trent et al. 1983\; JT\; MT]"	
"sup-18"	"III"	-0.54	"[C.elegansII] n463spo : strong recessive suppressor of sup-10(n983), weak suppressor of unc-93(e1500). No phenotype alone.  OA>10: n527, n528, n1010, n1033, n1038 etc. [Greenwald and Horvitz 1986\; MT]"	
"sup-19"	"V"	19.4694	"[C.elegansII] m210 :  weak recessive suppressor of unc-15(e73). [Brown and Riddle 1985\; DR]"	
"sup-21"	"X"	0.632494	"[C.elegansII] e1957sd : amber suppressor, partially or completely suppresses amber mutations in many genes but not in unc-13\; no phenotype alone. ES3 in presence of tra-3(e1107) etc. ME3. OA1: e2064 (identical).  Anticodon mutation in tRNATrp (rtw-10). [Kondo et al. 1990]"	
"sup-22"	"IV"	-2.52644	"[C.elegansII] e2057 : weak amber suppressor, suppresses amber mutations in a few genes (tra-3, dpy-20)\; no phenotype alone. ES3 in presence of tra-3(e1107) ME3. NA1. [Hodgkin 1985\; Kondo et al. 1990]"	
"sup-23"	"IV"	1.79478	"[C.elegansII] e2059 : weak amber suppressor, suppresses amber mutations in a few genes (tra-3, dpy-20, lin-1)\; no phenotype alone. ES3 in presence of tra- 3(e1107) ME3. NA1. [Hodgkin 1985\; Kondo et al. 1990]"	
"sup-24"	"IV"	13.0884	"[C.elegansII] st354 : weak amber suppressor, suppresses unc-52(e669), weakly suppresses unc-13(e450)\; no gross phenotype alone.  ES3 in presence of unc-52(e669). OA7 (identical). Anticodon mutation in tRNATrp (rtw-4). [Kondo et al. 1990]"	
"sup-26"	"III"	-3.43316	"[C.elegansII] n1091sd : suppressor of her-1(n695sd)\; no phenotype alone.  OA1: ct49sd (similar). [BW\; LK]"	
"sup-27"	"V"	6.8937	"[C.elegansII] n1092sd : suppressor of her-1(n695sd)\; no phenotype alone. OA1: n1102sd (similar). [BW\; LK]"	
"sup-28"	"X"	0.642053	"[C.elegansII] e1958  : (pka sup-21) amber suppressor, suppresses tra-3(e1107), dpy-20(e2017), but not unc-13(e450)\; no gross phenotype alone.  ES3 in presence of tra-3(e1107), ME3. OA2 (identical). Anticodon mutation in tRNATrp (rtw-8). [Kondo et al. 1990]"	
"sup-29"	"IV"	-2.81344	"[C.elegansII] e1986 : (pka sup-22) very weak amber suppressor, suppresses tra-3(e1107)\; no phenotype alone.  ES3 in presence of tra-3(e1107, ME3. OA2 (identical). Anticodon mutation in tRNATrp (rtw-9). [Kondo et al. 1990]"	
"sup-34"	"I"	-17.7062	"[C.elegansII] e2227 : weak amber suppressor, suppresses tra-3(e1107), weakly suppresses unc-52(e669). Anticodon mutation in tRNATrp (rtw-12). NA1. [Kondo et al. 1990]"	
"sup-35"	"III"	5.84096	"[C.elegansII] e2220 :  recessive suppressor of ts alleles of pha-1 (e2123 and t1001). No other phenotype. OA>100: e2221, e2223, etc. [Schnabel et al. 1991]"	
"sup-38"	"IV"	10.9762	"[C.elegansII] ra5sd : semidominant suppressor of class 1(paralysed) unc-52 alleles\; does not suppress Unc-52 gonad defects, nor lethal (class 2 and 3) unc-52 alleles.  In unc-52(+) background, ra5 homozygotes exhibit some muscle fragility, low brood size (<30).  Probable gf allele.  OA4(sd):ra14 (brood <10), ra18, ra21 (weaker). Also intragenic revertants: ra5ra60 (Mel, progeny die as larvae\; rescued zygotically\; probable null), ra5ra55 (leaky, viable).  Also lf allele: n2667 (abnormal axon growth, processes missing in left ventral nerve cord. [Gilchrist and Moerman 1992\; DM\; EG\; MT]"	
"sup-39"	"II"	0.204478	"[C.elegansII] je5 : dominant suppressor of unc-73(e936). Impenetrant embryonic lethal, escapers almost WT, abnormal double row of oocyte nuclei.  OA1: je6. [JW]"	
"sup-40"	"I"	0.42	"[C.elegansII] lb130 : dominant suppressor of unc-8(e15), unc-8(n491). Also recessive phenotypes, independent of unc-8 genotype: slow growth, sterility (abnormal oocytes), swollen hypodermal nuclei in adult, resistant to NDG (nordihydroguiaretic acid). [Shreffler et al. 1995\; MP]"	
"sup-41"	"IV"	2.11961	"[C.elegansII] lb125 : dominant suppressor of unc-8(e15), unc-8(n491). Also partial suppressor of deg-1(u38). [Shreffler et al. 1995\; MP]"	
"sur-2"	"I"	26.3002	"[C.elegansII] ku9 : suppressor of let-60(gf)\; pleiotropic effects, some gonadal abnormality, vulval defects, larval lethality, Egl, male tail defects\; ku9\/Df stronger Vul phenotype.  OA7: ku9, ku31, ku42, ku115amb (all similar to ku9\; all nonsense mutations), ku60 (Egl non-Vul) etc. Cloned: 5kb transcript, enriched in embryo and early larva\; encodes predicted 1586 aa novel protein.  sur-2:lacZ expressed in VPC during vulval differentiation. [Singh and Han 1995\; MH]"	
"sus-1"	"III"	-12.5852	"[C.elegansII] m156 : reduces suppression by sup-3 alleles\; enchances paralysed phenotype of unc-15(e73) unc-54(e190)\; no phenotype alone. ES1.  OA1: m155. [Brown and Riddle 1985]"	
"suv-1"	"X"	-15.8401	"[C.elegansII] n1329 : suppresses vulvaless phenotype of lin-10(n1390)\; complex suppressive or enhancing interactions with other vulva determination genes\; no phenotype alone.  OA11. [MT]"	
"suv-2"	"X"	5.63924	"[C.elegansII] n1694 : suppresses vulvaless phenotype of lin-10(n1390).  OA6. [MT]"	
"tab-1"	"II"	0.16736	"[C.elegansII] u271 : fails to respond to prod (strong touch).NA1. [TU]"	
"tax-2"	"I"	3.35	"[C.elegansII] p671 : defects in chemotaxis (all attractants), athermotactic\; Odr\; dye-filling reveals some amphid and phasmid axon defects.  OA5: p691, p694. ks10, etc. [Dusenbery 1976\; CX\; FK]"	
"tax-4"	"III"	0.27679	"[C.elegansII] p678 : defective chemotaxis to Na, cAMP\; repelled by Cl\; athermotactic\; reduced brood size.  OA3: p674, ks28, ks11 (athermotactic\; defects in sensory axon outgrowth). Cloned: encodes predicted 772 aa protein with 36\% identity to human cGMP-gated ion channel. [Dusenbery 1976\; FK]"	
"tpa-1"	"IV"	-28	"[C.elegansII] k501sd : resistant to 0.1 micromolar TPA.  OA>4. Cloned: two transcripts, different 5' ends\; encode 80 kD (A) and 65 kD (B) proteins\; closest similarity to mammalian PKC delta. [Tabuse et al. 1989\; Sano et al. 1995\; MJ]"	
"tra-1"	"III"	6.69566	"[C.elegansII] e1099 : XX animals transformed into low fertility males\; gonad morphology variable, testes reduced in size, few sperm made\; XO phenotype male, similar gonad defects. ES3 ME1 (XX, XO). OA>20 (recessive): e1834ird (deletion, probable null, resembles e1099), e1781amb (soma male, gonad contains apparent oocytes), e1488 (gonad and intestine hermaphrodite (self-fertile), rest of body male), e1732 (gonad more masculinized than body), rh132(gonad male, tail hermaphrodite)  etc. Also gain-of-function alleles:  e1575sd (pka her-2, both XX and XO animals transformed into fertile females by e1575 or e1575\/+. ES3 ME0. OA>20 (dominant): many weaker than e1575, causing incomplete or slight feminization. Also intragenic revertants of dominants, XX masculinizing.  OA>30.  Also additional phenotypic classes, complex properties. Cloned: 1.5 and 5 kb transcripts, encoding 288 aa and 1110 aa proteins with 2 and 5 zinc finger motifs, similarity to GLI family.  [Hodgkin 1987\; Zarkower and Hodgkin 1992\; CB\; DZ\; JK]"	
"tra-2"	"II"	0.164702	"[C.elegansII] e1095sd : XX animals transformed into infertile males with abnormal tail anatomy\; gonad morphology male, normal spermatogenesis\; XO phenotype wildtype male\; e1095\/+ is Egl hermaphrodite.  Probable null phenotype.  ES3 ME3 (XO) ME0 (XX). OA>20 (recessive): e1425amb (resembles e1095)\; q276 (XX animals transformed into mating males, anomalous non-null)\;f70 (masculinized self-fertile hermaphrodite), e1875 (slightly Egl hermaphrodite, very weak allele), b202ts (self-fertile hermaphrodite at 16C, Tra-2 at 25C) etc. Also hypermorphic gf alleles: e2020dm (XX animals completely feminized, XO animals fertile males, slightly feminized\;e2020\/+ XX also female).  OA>6 (hypermorphic):e2046 etc. (all weaker than e2020). Also constitutive gf alleles: e2531dm(e2531 and e531\/+ XO animals hermaphrodite, no effect on XX). OA9 (consititutive): all resemble e2531.  Intragenic revertants of both gf types are lf (XX masculinizing). Also mixed effect alleles: e1941, e2021(dominant feminizing effect on XX germline,recessive weak masculinization of XX soma). Cloned: 1.8, 1.9, 4.7 kb transcripts\; largest encodes 1475 aa TRA-2A protein, nine TM domains.Complex regulation and expression. Downstream gene in operon with ppp-1. [Klass et al. 1976\; Doniach 1986\; Kuwabaraet al. 1992\; Kuwabara 1996\; BG\; CB\; JK\; PK]"	
"tra-3"	"IV"	11.8464	"[C.elegansII] e1107amb,mat : XX progeny of homozygous parents are abnormal sterile males or intersexes, occasionally self-fertile, especially at 15C (15C brood 1\% of wildtype)\; XO phenotype wildtype.  Either maternal or zygotic expression of tra-3(+) sufficient for normal XX hermaphrodite development. ES3 (progeny testing) ME0 (XX) ME3 (XO). OA>5: e1525amb, e1767(non-amb), y240 etc.(resemble e1107, probable nulls), bn75ts (Mog 25C),e2333 (XX anatomically WT, brood size increased). Amber alleles very efficiently suppressed\;used for sup-7 transgene selection. Cloned: encodes predicted protein with similarity to vertebrate protease calpain, but lacking calcium-binding domains. [Hodgkin 1986\; Fire 1986\; Hodgkin and Barnes 1991\; CB]"	
"ttx-2"	"III"	-1.61117	"[C.elegansII] ks4 : mutant animals cryophilic, occasionally moves isothermally on a thermal gradient\; stronger phenotype if grown 15C. No obvious abnormality in chemotaxis to NaCl, osmotic avoidance, male mating or dauer formation. Cloned: cosmid rescue (F52H10)[FK]"	
"ttx-3"	"X"	6.2	"[C.elegansII] ks5 : mutant animals cryophilic, almost completely defective in isothermal tracking. No obvious abnormalities in chemotaxis to NaCl, osmotic avoidance, male mating, or dauer formation. [FK]"	
"unc-1"	"X"	-18.703	"[C.elegansII] e719 : recessive kinker, putative null. Suppresses anaesthetic hypersensitivity of unc-79 and unc-80 mutants.  ES3 ME1. OA>10(recessive): e50, e68, e114 (anomalous allele, transdominant suppressor of n494sd), etc. Also neomorph\/antimorph gf alleles: e94sd (former reference allele, recessive kinker\; e94\/+ is weak coiler. ES2 ME2), e1598dm (pka unc-102, both homozygote and e1598\/+ are strong Ric coilers\; intragenic revertants of e1598 resemble e719. ES3 ME0). OA>8 (dominant and semidominant)\;n496, n775 (strongly dominant), n494 (weaklysemidominant), etc.  Complex complementation among unc-1 alleles. [Park and Horvitz 1986a\; Morgan and Sedensky 1994\; CW]"	
"unc-2"	"X"	-13.3989	"[C.elegansII] e55 : weak kinker\; sluggish\; thin\; hypersensitive to serotonin, fails to desensitize to dopamine. ES3 ME2. OA>10: e97, e129, e2379 (Unc, only subtle defect in adaptation), mu74 (resembles e55, deletion,probable null), pk95tci, etc. Cloned: 7.5 kb transcript, present throughout development, encodes protein homologous (41-65\%)to alpha1 subunit of mammalian neuronal voltage-sensitive calcium channel. [Schafer and Kenyon 1995\; DM]"	
"unc-3"	"X"	18.5633	"[C.elegansII] e151 : weak coiler tends to coil, tail active, good head movement\; very disorganized ventral nerve cord\; mosaic analysis indicates mutant focus in ventral cord motor neurons.  Similar phenotype ine151\/Df.  ES3 ME1.OA>5: e54 (weaker allele), e95, mn419, p1001 etc. Cloned: polymorphisms identified in mn419 and derivatives (cosmid F42D1). [Brenner 1974\; Herman and Kari 1987\; NG\; SP]"	
"unc-4"	"II"	1.75256	"[C.elegansII] e120 : large, healthy, active, moves forward well but cannot back\; ventral cord VA motoneurons have normal anatomy but most have synaptic inputs appropriate to VB motoneurons. ES3 ME1. OA>15: e26, e2151, e2308, e2320 (deletion null,resembles e120), e2322ts (TSP L2-L3),wd1 etc.  See also unc-37. Cloned: rare 1.2 kb transcript, encodes homeoprotein (pka ceh-4)\; unc-4:lacZ expressed in VA but not VB motor neurons. [White et al. 1992\; Miller et al. 1992\; NC]"	
"unc-5"	"IV"	1.94124	"[C.elegansII] e53 : severe coiler, grows well\; L1 also severe coiler\; dorsal hypodermal cells abnormal, dorsal nerve cord absent or almost absent, cord commissures fail to reach targets\; muscle arms misdirected\; distribution of cell bodies in ventral cord is disorganized\; abnormal gonad arms\;Egl-c. ES3 ME0. OA>10: e553 (resembles e53), e152 (weaker phenotype behaviorally and anatomically, dorsal cord partially formed), bx8, ev447,st1001tci, etc.  See also unc-6, unc-40. Cloned: 3.0 and 3.1 kb transcripts (different 5') ,encode predicted 919 aa transmembrane protein,2 Ig domains and 2 TSP domains. Mosaic analysis indicates autonomous action in neurons, DTC\; ectopic expression in touch cells can cause their dorsalward migration. [Hedgecock et al. 1990\; Leung-Hagesteijn et al. 1992\; Hamelin et al. 1993\; NW]"	
"unc-6"	"X"	-2.22837	"[C.elegansII] e78 : slight kinker, poor backing\; large, healthy, slightly fat\; dorsal extensions of DD and VD neurons grow in aberrant directions fail to reach dorsal cord\; ventral cord disorganized\; abnormal gonad arms, etc. ES3 ME1. OA>20: e7, e181, ev400 (pka unc-106,uncoordinated, high frequency of phasmid axon displacement), n593, n594 etc. Some alleles (rh202, rh204, rh402 etc.) defective only in dorsalward migrations.  Null alleles defective in both dorsalward and ventralward migrations.  See also unc-5, unc-40. Cloned: encodes extracellular matrix component, laminin-related at N-term, homologous to vertebrate netrins. [Ishii et al. 1992\; NW]"	
"unc-7"	"X"	20.3563	"[C.elegansII] e5 : moves backward better than forward, kinker in forward movement, active, healthy, slightly thin. Suppresses anaesthetic hypersensitivity of unc-79 and unc-80 mutants. e5\/Df similar, null phenotype.ES3 ME0. OA>20: e42, e65 (pka unc-12, weaker), bx5::Tc1, st197, mn384 (weaker allele), etc.\; also revertants bx5mn369 etc. Cloned: main transcript 2.9 kb, encodes predicted 522 aa membrane protein related to EAT-5, Drosophila passover (26\%identity), etc\; possible gap junction component. [Starich et al. 1993\; Morgan and Sedensky  1994\; EH\; SP]"	
"unc-8"	"IV"	3.29192	"[C.elegansII] e49 : moves well but slowly and irregularly, often kinking both forward and backward\; swollen ventral cord motor neurons\;e49\/+ very slightly uncoordinated. ES2 ME1. NA1 (recessive). Also dominant coiler alleles:  e15sd (pka unc-28,  ES3 ME0), n491sd (homozygotes strong coilers, n491\/+ coiler, slightly weaker phenotype). Intragenic revertants of n491 (e.g. n491n1192) are wildtype thus unc-8 null phenotype may be wildtype.  OA3 (dominant):n492, n773.  See also extragenic suppressors sup-40, 41, 42. [Park and Horvitz 1986a\; Shreffler et al. 1995\; MP]"	
"unc-9"	"X"	11.4878	"[C.elegansII] e101 : moves backward better than forward slight kinker in forward movement active healthy\; larvae more severely uncoordinated\; suppresses anaesthetic hypersensitivity of unc-79 and unc-80\; male fan slightly reduced, spicules tend to protrude. ES2 ME0. OA3: e101, ec27, bx5, e111. Cloned: cosmid rescue (R12H7). [Brenner 1974\; Morgan and Sedensky 1994\; CW\; MQ]"	
"unc-10"	"X"	-1.99	"[C.elegansII] e102 : weak coiler, tends to back, loopy movement in reverse\; fairly active\; slightly small and thin\; Ric. ES3 ME2. OA1: e126. [Brenner 1974\; Nguyen et al. 1995]"	
"unc-11"	"I"	-2.42282	"[C.elegansII] e47 : kinker, jerky ratchet-like movement especially in reverse\; slow pharyngeal pumping\; slightly small and thin\; Ric, elevated acetylcholine levels, hypersensitive to levamisole.  Some migration defects.ES3 ME2. OA3: e511, e1024 (weaker), h1008Cloned: cosmid rescue (C32E8).  Multiple transcripts. [Brenner 1974\; Nguyen et al. 1995\; AL\; NJ\; RM\; TN]"	
"unc-13"	"I"	2.04708	"[C.elegansII] e51 : paralysed, kinky, small, irregular pharyngeal pumping\; able to lay eggs. Ric, high acetylcholine levels\; variable neuroanatomical defects.ES3 ME0. OA>30: e450amb, e312amb (non-null),e309 (suppressed by sup-6), s69, s178 etc.  All alleles similar to e51 or slightly weaker. Cloned: very large gene, encodes 1734 aa novel protein with contains phorbol ester (diacylglycerol) binding site.  Antibodies detect 190 kD UNC-13. [Brenner 1974\; Ahmed et al. 1992\; Nguyen et al. 1995]"	
"unc-14"	"I"	1.80092	"[C.elegansII] e57 : very sluggish, almost paralysed\; small and dumpyish tends to coil\; some egg retention\; PVP defects.ES3 ME0. OA>5: e157 (multiple aspects of axon outgrowth affected\; nerve processes contain large abnormal varicosities),e608, e866, e1119, etc. Cloned: cosmid rescue (R05H7). [Brenner 1974\; McIntire et al. 1992\; FK\; MQ\; MT\; NJ]"	
"unc-15"	"I"	2.01829	"[C.elegansII] e73 : limp paralysed phenotype, larvae move slightly better\; Egl\; disorganized muscle structure\; suppressed by sup-3\; e73\/+ slightly slow. ES3 ME0. OA>10: e1214amb (more severe phenotype than e73, not suppressed by sup-3), e1402ts (moves well at 15C, paralysed at 25C), ut37 (lethal embryonic arrest at 4-fold stage), r404, r408, m81, s40, su228 etc. Cloned: encodes 886 aa paramyosin.  Extensive structural analysis. [Kagawa et al. 1989\; Gengyo-Ando and Kagawa 1991\; Epstein et al. 1993\; HE\; HK]"	
"unc-16"	"III"	0.5585	"[C.elegansII] e109 : very sluggish small\; males more active. ES3 ME2. OA1: n730ts (pka egl-39, transient bloating at 25C\; sensitive to serotonin and to imipramine\; uncoordinated sluggish weak coiler phenotype. ES3 (adult 25C) ES2 (other stages 25C), ME2). [Brenner 1974\; Trent et al. 1983\; JT]"	
"unc-17"	"IV"	-3.3038	"[C.elegansII] e245 : severe coiler at all stages, rather small and thin\; slow irregular pumping\;Ric, resistant to 0.1 mM lannate\; suppressed by sup-1, sup-2 and sup-8\; normal ChAT (choline acetyltransferase) levels. ES3 ME0. OA>10: ut64 (embryonic lethal, coiler, probable null), e335, e464 etc.(most viable alleles resemble e245 or slightly weaker). Also anomalous alleles: e113 (less uncoordinated phenotype, drug sensitive, loopy movement, reduced ChAT levels, Egl-c), e876 (similar), p1156 (Smg suppressible, fails to complement unc-17 and cha-1). cha-1-unc-17 is a complex locus. Cloned: 2 kb transcript, 5' UTR exon shared with cha-1\; encodes predicted 532 aa vesicular acetylcholine transporter\; 12 TM domains.Antibody staining punctate, most motor synapses. [Alfonso et al. 1993, 1994\; AL\; RM]"	
"unc-18"	"X"	-1.39093	"[C.elegansII] e81 : paralysed, kinky, thin at all stages\; able to lay eggs\; Ric\; elevated levels of acetylcholine.ES3 ME0 OA>1: e174 (pka unc-19, similar),  e234 (pka lan-2, Ric),e2146, b403, cn347, md118, md193 etc. Cloned: encodes predicted 591 aa protein, with similarity to yeast Sly1p, Sec1p, Slp1p secretory proteins.  Antibody stains along axons in nerve cords [Gengyo-Ando et al. 1993\; Nguyen et al. 1995\; RM\; TN]"	
"unc-20"	"X"	-11.9594	"[C.elegansII] e112ts : at 25C severe kinker, some coiling\; active, healthy\; some head muscle contraction\; defects in longitudinal axon elongation in VNC. ES3 (25C) ME0 (25C)\; at 15C wildtype. OA>5: (6 Smg-enhanced or Smg-dependent alleles). [Brenner 1974\; NG\; TR]"	
"unc-22"	"IV"	5.45984	"[C.elegansII] e66 : twitcher at all stages\; (moves slowly with constant trembling)\; thin\; abnormal muscle structure\; unable to hypercontract and therefore levamisole resistant\; Egl\; e66\/+ twitches in 1\% nicotine\; ES3 ME0. OA>200:s32amb (resembles e66), m52dm,e105 (muscle structure near normal),e2428, s7, s12 (near normal muscle structure),s2038,st192 etc.  Many Tc1 insertions, plus precise and imprecise excision revertants. Most unc-22\/+ heterozygotes twitch in nicotine. Cloned: large gene (>30 kb), transcript ~19 kb,encodes 6049 aa twitchin: single kinase domain, multiple copies of fibronectin-like and Ig-like repeats.  Antibody staining indicates twitchin associated with thick filaments. [Waterston et al. 1980\; Benian et al. 1989, 1993\; GB]"	
"unc-23"	"V"	1.86822	"[C.elegansII] e25 : \"benthead\" phenotype, progressive dystrophy of head musculature so that adult head is bent dorsally or ventrally, hence very poor forward movement, good reverse movement\; defects in muscle attachment (Mua)\; Egl. Phenotype partly suppressed by growth in liquid. ES3 (adult) ME1. OA>10: e324 (resembles e25), e611 (pka vab-4, impenetrant allele), e988, e2154 etc. [Waterston et al. 1980\; CB\; DR\; NJ]"	
"unc-24"	"IV"	3.54257	"[C.elegansII] e138amb : weak kinker, tends to back, often forms omega shape\; fairly active\; healthy. Severe kinker in L1.  Suppresses anaesthetic hypersensitivity of unc-79 and unc-80 mutants.ES3 ME1. OA>10: e448, e927pdi, e1172icr, e2386, q327 etc. Cloned: cosmid rescue (C56C3). [Riddle and Brenner 1978\; Morgan et al. 1991\; MQ]"	
"unc-25"	"III"	20.8947	"[C.elegansII] e156 : shrinker, contracts both dorsally and ventrally when prodded\; slow\; loopy Fab\; poor backing\; slightly small\; Exp defect in defecation\; deficient in GABA\; some neuroanatomical defects (D motorneurons). ES3 ME2. OA>5: e265, e591, sa4, sa25 (similar). Cloned: encodes 416 aa GAD (glutamic aciddecarboxylase), 45\% identity to human GAD65,67. unc-25:lacZ expressed in all GABAergic neurons. [Thomas 1990\; McIntire et al. 1993\; CZ\; JT\; MT]"	
"unc-26"	"IV"	8.22742	"[C.elegansII] e205amb : severe kinker, small, scrawny, flaccid little movement\; slow pharyngeal pumping\; Ric. ES3 ME0 OA>10: e176, e345 (pka unc-48), e314 (strong Exp, weak Unc, Eat), e2340, m2, n1307, s1710mut, ad473, ad701, etc. Some (5\/18) alleles have expulsion defect in defecation.  Gene is recombinationally large. [Charest et al. 1990\; Avery 1993\; DA\; EG\; JT\; RM]"	
"unc-27"	"X"	0.330008	"[C.elegansII] e155 : sluggish, poor backing, slightly dumpy\; abnormal body muscle\; some neuroanatomical defects.  ES3 ME2.  NA1. Also sd alleles:su142sd (pka unc-99, very slow, almost paralysed\; can lay eggs\; abnormal faint muscle birefringence and ultrastructure, collections of thick or thin filaments. ES3 ME1). OA3 (sd):su195 (forms thin filament paracrystals), su215 etc. [Brenner 1974\; Zengel and Epstein 1980\;SQ]"	
"unc-30"	"IV"	7.8081	"[C.elegansII] e191 : shrinker, contracts both dorsally and ventrally when touched\; slow good forward movement but poor backing, rather small\; VD and DD motoneuron axons are displaced and fail to stain with anti-GABA antibodies\; PVP neurons also abnormal.ES3 ME2 OA>10: e165, e318, e646 (R44och), e926pdi (deletion), e2505, bx8, etc.). Cloned: encodes predicted 318 aa protein with homeodomain, most similar to UNC-4. Antibody stains D neurons, certain other neurons.  Ectopic trans gene expression induces GABA expression. Locus naturally duplicated in some strains. [McIntire et al. 1993\; Jin et al. 1994\; CZ\; MT]"	
"unc-31"	"IV"	6.28225	"[C.elegansII] e169ts : very slow and sluggish, moves better in absence of bacteria\; insensitive to prodding\; constitutive pharyngeal pumping\; weak Daf-c\; poor dauer recovery\; Egl. More active when starved. No obvious changes in neuroanatomy.ES2 ME1 OA>10: e69amb, e86, e375amb, n1304(all resemble e169), n422ts (pka egl-22, variable transient bloating at 25C, stimulated by serotonin and by imipramine\; uncoordinated limp paralysed phenotype. ES3 (adult, larvae)), e928 (strongest allele, deletion null\; resembles e169), n577ts, st198, u378, z1, etc. Cloned: encodes predicted 138 kD novel protein\; antibody stains axons of most neurons.  See also rsn-13. [Avery et al. 1993\; CB\; DA\; MT]"	
"unc-32"	"III"	0.002369	"[C.elegansII] e189 : severe coiler, little movement in adult\; moves well in L1 but coils in response to touch in L2 and later stages\; rather small and thin\; weakly Egl-c\; Ric. ES3 ME0. OA>5: f123 (lethal, f123\/e189 coiler),f121 (lethal, f121\/e189 almost WT), ut61, ut111(embryonic lethals, irregular shape).  Most alleles lethal. Cloned: probably encodes protein with homology to glutathione reductase (ZK637.10)\; downstream gene in operon. [Brenner 1974\; Nguyen et al. 1995\; FF\; JC]"	
"unc-33"	"IV"	-3.54569	"[C.elegansII] e204 : very slow, almost paralysed\; tends to curl\; dumpyish\; weak FITC uptake\; amphid, phasmid, PDE, PVP axons abnormal\; multiple defects in axonogenesis\; abnormally abundant neuronal microtubules. ES3 ME0. OA>10: e572, e735, e1358, m7,mn260::Tc4, rh1030::Tc4, etc. Cloned: 2.8, 3.3, 3.8 kb transcripts (different 5' ends) encoding predicted 523 aa, 679 aa, 854 aa proteins with similarity to collapsin??? Antibody stains all neuron processes in larvae and adults. [Hedgecock et al. 1985\; Li et al. 1992\; EH\; SP]"	
"unc-34"	"V"	-20.2993	"[C.elegansII] e315ts : at 20C fairly severe coiler, somewhat active, grows well\; male has crumpled copulatory spicules\; variable defects in VD and DD commissures\; At 15C moves much better.  Low penetrance withered tail phenotype (CAN cell defect),and excretory cell abnormalities.ES3 (20C) ME0. OA>5: e566, (strongest allele,non-ts, coils at all temperatures\; defects in axonal elongation and fasciculation), e951pdi, s138gri, etc. [Brenner 1974\; McIntire et al. 1992\; CX\; NG\; NW\; MT]"	
"unc-35"	"I"	-14.2441	"[C.elegansII] e259 : loopy irregular forward movement, poor backing\; active\; slightly thin. ES2. ME2. NA1. [Brenner 1974]"	
"unc-36"	"III"	-0.347379	"[C.elegansII] e251 : very slow, almost paralysed, thin\; loopy at rest\; normal ventral nerve cord ultrastructure\; Ric\; hypersensitive to serotonin, fails to adapt to dopamine (likeUnc-2)\; hypersensitive to calcium channel modulators such as verapamil. Pharyngeal pumping slow and irregular, slippery corpus and isthmus\; increased sensitivity to arecoline. Mosaic analysis indicates focus in nervous system.  ES3 ME0. OA>8: e418 (resembles e251)\; eT1(III\;V) (pka unc-72(e873), presumed breakpoint, ME1),e1501, e2341, ad698, etc. Cloned: encodes predicted proteins with similarity (~45\% identity) to alpha2 subunit of L-type calcium channel. [Brenner 1974\; Avery 1993\; Nguyen et al. 1995\; MT]"	
"unc-37"	"I"	1.30766	"[C.elegansII] e262 : weak coiler, fairly active\; phenotype similar to Unc-4. ES2 ME1. OA2 (recessive): s80  (pka let-76, L1 lethal), h763 (Unc, adult sterile).  Also dominant suppressors of unc-4(e2322ts):wd14, wd16, wd17, wd18 (no phenotype alone, allele-specific dominant suppressors of e2322). Intragenic revertants, e.g. wd17wd19, resembl eh763. Cloned: encodes predicted 614 aa protein with similarity to groucho-related transcription factors, 6 WD40 repeats in C-term. [Miller et al. 1993\; NC]"	
"unc-38"	"I"	-0.594752	"[C.elegansII] e264 : weak kinker, sluggish, slightly dumpyish sometimes Egl, resistant to 1mM levamisole in body but not in head\; sensitive to hypoosmotic shock. ES3 ME2. OA>40:  e213, e743, x20, etc. Cloned: encodes subunit of nicotinic acetylcholine receptor. [Lewis et al. 1980\; ZZ]"	
"unc-39"	"V"	5.88093	"[C.elegansII] e257 : fairly severe kinker, can move forward and backward\; fairly active, slightly dumpy\; often withered tail as a result of80\% CAN migration defect\; other migrations also variably defective.  15\% of hermaphrodites have third gonad arm arising from additional somatic gonad founder, \"Z5\". e257\/Df more severe phenotypes.  ES2 ME1. OA2: ct73 (pka mig-3,abnormal migration of CAN cells), rh72. [Hedgecock et al. 1987\; Manser and Wood 1990\; CF\; NJ]"	
"unc-40"	"I"	0.289722	"[C.elegansII] e271 : weak kinker, dumpyish, slow but fairly active\; Egl\; variable defects in VD and DD commissures\; general failure in ventralward migrations. ES2 ME0. OA>5: e1430 (pka unc-91, e1478,n324, n473, ev457 (probable null), etc. Cloned: encodes predicted large protein with TM domain,extracellular fibronectin and Ig domains\; related to chicken neogenin, human tumor suppressor DCC.  unc-40:GFP expressed in cells undergoing circumferential migrations or extensions. [Hedgecock et al. 1990\; NW]"	
"unc-41"	"V"	2.28914	"[C.elegansII] e268 : weak kinker, irregular jerky movement, slightly small\; VD1, VD2, DD1 cell bodies mispositioned, usually anteriorly\; RVG organization disrupted\; Ric\; elevated acetycholine levels.  e268\/Df similar.ES3 ME0. OA8: e252, e399, e1175, e1294,cn252::Tc1 etc.(similar). Also anomalous alleles: e554, e1162 (normal acetylcholinelevels, larger size, sd Unc phenotype.) Cloned: partial sequence indicates novel predicted protein. [Nguyen et al. 1995\; RM\; TN]"	
"unc-42"	"V"	2.19874	"[C.elegansII] e270 : medium kinker, sometimes backs in response to tail touch, slightly small, fairly active, grows well\;  Egl-c\;  HSN fasciculation abnormal. ES3 ME1. Similar phenotypes in e270\/Df. OA>5: e419, e623, e2325, s260, m435, etc. [Brenner 1974\; NG]"	
"unc-43"	"IV"	4.59	"[C.elegansII] e408 : slow, lazy, slightly rippling movement poor backing thin\; almost paralysed, tends to shrink and relax when prodded\; larvae move better\; Egl-c.ES3 (adult) ME1.  OA>5: e266 (similar Unc, Egl-c, echo in defecation cycle\; exhibits muscle activation defects in some tissues, muscle hyperactivation in others), e300 (shorter than e408, shrinking more marked), e755, sa200 (pka dec-8, weaker allele, Dec non-Unc\;sa200\/Df is Unc). Also gain-of-function allele:  n498sd small, almost paralysed, Egl\; Daf-c at 27C\; n498\/+ less severe).  Intragenic revertants e.g. n498n1179 have recessive uncoordinated phenotype. [Park and Horvitz 1986\; JT]"	
"unc-44"	"IV"	2.86627	"[C.elegansII] e362 : paralysed coiler, dumpy, tends to curl\; weak FITC uptake\; amphid, phasmid,PVP, PDE  and other axons abnormal. ES3 ME0. NA11: e427, e638, e1197 (multiple defects in axonal elongation, fasciculation etc.), e1260,q331:Tc1, rh1013::Tc1, st200::Tc5, etc. Cloned: multiple transcripts up to 14 kb in length, encoding proteins related to mammalian ankyrin, up to 23 repeats of 33 aa ANK repeat [McIntire et al. 1992\; Otsuka et al. 1995\; DD]"	
"unc-45"	"III"	-27.1027	"[C.elegansII] e286ts : at 25C limp paralysed Egl\; muscle ultrastructure defective, few thick filaments\; males move better\; at 20C slow, at 15C wildtype. ES3 (adult 25C) ME0. OA>5: m94ts, r450ts, su2002 (some ts alleles have stronger 20C phenotype than e286). Also lethal Pat alleles: st601, st603,(limited development beyond two-fold,no pharyngeal pumping, failure to assemble thick filaments), st604 (weaker allele, some maternal rescue), wc2, wc4, wc5. [Venolia and Waterston 1990\; LV]"	
"unc-46"	"V"	-2.32403	"[C.elegansII] e177 : shrinker contracts both dorsally and ventrally when prodded, slow, good forward movement, poor backing\; slightly small. ES3 ME2. OA2: e300, e642. [Brenner 1974\; McIntire et al. 1993\; MT]"	
"unc-47"	"III"	1.91692	"[C.elegansII] e307 : very poor backing, good slow forward movement\; slight shrinker (contracts both dorsally and ventrally when prodded)\; small\; abnormal staining with anti-GABA antibodies (accumulates GABA).ES3 ME2. OA2: e542, e707. [Brenner 1974\; McIntire et al. 1993\; EG\; MT]"	
"unc-49"	"III"	3.35793	"[C.elegansII] e382 : shrinker, contracts both dorsally and ventrally when prodded\; slow\;  poor backing, slightly small.  Probable defect in inhibitory GABA receptor function. ES3 ME2. OA>5: e407, e468, e929, n1324 etc. Cloned: encodes predicted GABA-A receptor. In probable operon with two other GABA receptor subunits. [Brenner 1974\; McIntire et al. 1993\; EG\; MT]"	
"unc-50"	"III"	2.40282	"[C.elegansII] e306 : weak kinker, slow but fairly active\; resistant to 1 mM levamisole sensitive to hypoosmotic shock.  Extracts lack levamisole binding.  ES3 ME1. OA6: e425 etc. (all similar). Cloned: encodes predicted 301 aa novel protein, possible TM domain. [Lewis et al. 1980\; MT\; WS\; ZZ]"	
"unc-51"	"V"	24.4045	"[C.elegansII] e369amb : paralysed dumpy tends to curl\; Egl\; dorsal extensions of DD and VD neurons grow in aberrant directions fail to connect to dorsal nerve cord\; amphid, phasmid, PDE and other axons abnormal\; multiple defects in axon elongation, fasciculation,etc.  Abnormal axon ultrastructure: varicosities, cisternae, abnormal vesicles.ES3 ME0. OA>10: e389, e432, e584, e1212 etc. Cloned: 3.1 kb transcript, encodes predicted 856 aa protein with similarity to Ser\/Thrkinases.  unc-51: lacZ expressed in neurons. [Hedgecock et al. 1985\; McIntire et al. 1992\; Ogura et al. 1994\; FK\; FR]"	
"unc-52"	"II"	23.2984	"[C.elegansII] e444 : adults limp, paralysed except for head region\; thin\; Egl\; larvae move well\; progressive dystrophy, body muscles fail to accumulate myofilaments. Class 1 allele. ES3 (adult) ME0. OA>10 (class 1): e669amb (well suppressed), e998 (stronger phenotype), su200, r290 etc. Also class 2 mutations: st549 (lethal, severe Pat, no organized myofilament lattice\; probable null), st546, st560 etc. (all similar to st549). Also class 3 mutation: ut111 (lethal, arrest at two-fold\; not paralysed\; complements class 1 alleles.  See also sup-38, smu. Cloned: multiple transcripts (4.0, 6.5, 8.0 kb)g enerated by alternative RNA processing\; encode proteins related to perlecan (matrix heparansulfate proteoglycan)[Rogalski et al. 1993, 1995\; DM]"	
"unc-53"	"II"	3.07129	"[C.elegansII] e404 : sluggish, poor backing, dumpyish\; somewhat Egl\; multiple defects in neuronal outgrowth, branching\; also defects in excretory canal extension, gonad arm growth\; males have abnormal bursal anatomy. ES2 ME0. OA>5: n152, n166, n569 (synergizes with sem-5(n177) to give strong Sem migration defect),e2432, e2499, etc.  Null phenotype uncertain\; some lethality in strong alleles. Cloned: multiple transcripts (different 5' ends)\; one encodes 1528 aa protein, predicted to bind actin, ATP\/GTP\; may interact with SEM-5.  Transgene overexpression leads to extension of growth cones along a-p axis. [Hedgecock et al. 1987\; Hekimi and Kershaw 1993\; UG]"	
"unc-54"	"I"	27.2264	"[C.elegansII] e190 : limp paralysed phenotype at all stages\; larvae can move slightly more than adults\; Egl\; muscle ultrastructure very disorganized few thick filaments. ES3 ME0. OA>50 (recessive): e1108amb,e1301ts, e675sd and s291 (in frame internal deletion mutants, almost paralysed slight twitchers), etc. Also unusual suppressor alleles, OA>15: s74 (dominant suppressor of unc-22(s12), recessive slow, stiff\; normal muscle ultrastructure) Also dominant antimorphic alleles, OA>10:e1152sd (severe rigid paralysis, small\;e1152\/+ paralysed weaker phenotype. ES3 ME0),r344 (recessive lethal, r344\/+ severely paralysed), etc.  Intragenic revertants have recessive paralysed phenotype.   Some recessive alleles (r274, e1420 etc.) are dominant antimorphs in smg background. Cloned: encodes MHC B (MYO-4), major bodywall muscle myosin heavy chain.  6 kb message,1117 aa protein.  Extensive molecular analysis. [Epstein et al. 1974\; McLachlan and Karn 1982\;Dibb et al. 1989\; Bejsovec and Anderson 1990\; TR\; RW]"	
"unc-55"	"I"	2.36253	"[C.elegansII] e402 : slow, very poor backing, tends to coil ventrally\; healthy\; abnormal VD neurons (adopt DD synaptic pattern).  Mosaic analysis indicates focus in VD neurons.ES3 ME0. OA>11: e523 etc. [Walthall and Plunkett 1995\; ER]"	
"unc-57"	"I"	-0.99493	"[C.elegansII] e406 : strong kinker, active\;  small and thin\; slow pharyngeal pumping\; tends to hypercontract. ES3 ME2. OA>5: e590.e957, e1190, st199, ad592 etc. [Brenner 1974\; Avery 1993\; DA]"	
"unc-58"	"X"	1.5164	"[C.elegansII] e665dm : `shaker', animals short, rigidly paralysed with constant shaking of body\; e665\/+ phenotype similar but weaker, animals slightly longer and less rigid. Muscle hyperactivated, sticky pumping, short.ES3 ME0. OA4 (dominant): e415, n495 (similar), e778 (weaker phenotype), etc. Dominant alleles revert intragenically e.g. e665e2112 : recessive weak Unc (probable null phenotype). [Brenner 1974\; Park and Horvitz 1986\; JT]"	
"unc-59"	"I"	23.4072	"[C.elegansII] e261 : poor backward movement, forward better\; thin\; vulva variably abnormal, often protrusive, sometimes ruptured\; many postembryonic lineage abnormalities resulting from variable failures in cytokinesis\; gonad lineages sometimes defective\; variable defects in neuroanatomy\; males have very abnormal tail anatomy. ES2 ME0. OA3: e1005 (pka unc-88), e1465, n391. [Brenner 1974\; White et al. 1982\; MT]"	
"unc-60"	"V"	-18.9252	"[C.elegansII] e723 : limp paralysed or very slow, thin, Egl\; abnormal muscle ultrastructure with large aggregates of thin filaments\; recessively suppressed by sup-12. ES3 ME0. OA>10: e677 (pka unc-66),  e890 (both resemble e723), e890, s1310 (induced on eT1), s1586 (500 bp deletion, larval lethal).  Also r398, s1307 (both antidystrophic alleles). Cloned: 1.3 and 0.7 kb alternative transcripts encoding 165 aa and 152 aa predicted proteins with 38\% identity, sharing only first exon and first methionine\; both have similarity to actin depolymerizing proteins (cofilin, destrin). [Waterston et al. 1980\; McKim et al. 1994\; BC]"	
"unc-61"	"V"	6.5269	"[C.elegansII] e228 : poor backing irregular waveform in forward movement\; thin\; protrusive vulva\; variable defects in neuroanatomy\; male tail very abnormal (rays absent, spicules reduced etc.). ES3 ME0. NA1. [Brenner 1974\; Siddiqui and Culotti 1991\; SQ]"	
"unc-62"	"V"	-5.44634	"[C.elegansII] e644 : slightly slow, irregular, sometimes rippling movement, especially in reverse\; slightly dumpy\; variable abnormalities in VD and DD commissures\; male tail abnormal, bursa small, fan reduced, rays variably absent. 19\% of embryos Nob. ES2 ME0. OA2: s472spo(pka let-328, lethal, probable null), ct344 (pka nob-5, partial maternal effect Nob, disorganized posterior). [Brenner 1974\; BC\; BW]"	
"unc-63"	"I"	-0.247649	"[C.elegansII] e214 : weak kinker, slow, inactive, resistant to 1 mM levamisole, sensitive to hypoosmotic shock\; elevated acetylcholine levels. ES3 ME2. OA>50: x13 (pka lev-7, Lev,Ric, poor backing\; ES3 ME3), x18, x37 etc. (most alleles resemble e214). Also rare exceptional alleles: x26 (almost normal movement, slight levamisole resistance), b404 (Ric, trichlorfon resistant, slight Lev, slight Unc), x33 (more resistant in body than in head).  Previous reference allele \"e384\" is double with unc-11. [Lewis et al. 1980\; Nguyen et al. 1995\; AL\; RM\; TN\; ZZ]"	
"unc-64"	"III"	21.4444	"[C.elegansII] e246 : sluggish, will move either forward or backward if prodded but almost immediately jams up\; Ric\; healthy\; elevated acetylcholine levels. ES2 ME0. OA>1 (some alleles lead to severe paralysis). Cloned: encodes predicted syntaxin homolog. [Brenner 1974\; Nguyen et al. 1995\; NM\; RM\; TN]"	
"unc-65"	"V"	6.57975	"[C.elegansII] e351 : slow, moves well, slightly poor backing\; partially lannate resistant (Ric)\; healthy\; sometimes Egl. ES2 ME2. OA1: e355. [Brenner 1974]"	
"unc-67"	"I"	-2.43374	"[C.elegansII] e713 : sluggish, can move well both forward and backward but frequently pauses or jams up. ES2 ME2. NA1. [Brenner 1974\; MQ]"	
"unc-68"	"V"	0.624712	"[C.elegansII] e540 : weak kinker, slow, thin\; slight shrinker\; head region but not body resistant to 1 mM levamisole, ouabain. ES3. ME2. OA>15: x14, x24, e932, e2313,s92spo, r1162 (presumed null, deletes all TM domains) etc.(all resemble e540). Cloned: 30 kb gene, 43 exons, encodes 4902 aa ryanodine receptor (43\% identity to mammalian cardiac RYR). [Brenner 1974\; Lewis et al. 1980\; HK\; TR]"	
"unc-68"	"V"	0.624712	"[C.elegansII] kh30 : semidominant convulsive behavior in 30mM ketamine or other NMDA antagonists\; recessive cs Unc\; variable motility\; weakly resistant to cholinergic agonists, ouabain\;normal muscle morphology. [HK]"	
"unc-69"	"III"	2.34638	"[C.elegansII] e587 : medium coiler, inactive, small\; abnormalities in VD and DD commissures, longitudinal axon elongation. ES3 ME0. OA1: e602. Cloned: cosmid rescue (C46D2). [Brenner 1974\; NG\; SQ\; WS]"	
"unc-70"	"V"	0.472695	"[C.elegansII] e524ts,sd : irregular loopy movement, sometimes coiling, active\; grows well.e524\/+ weak coiler at 25C. ES2 ME2. OA1 (sd): n493sd (curly, uncoordinated, non-ts). Revertants e.g. n493n1170ird have recessive lethal phenotype, early L1 arrest (probable null phenotype). OA7 (ird) 8. Also lethal alleles, OA>5: s115, s1406,s1639 etc. (all early\/mid larval lethals, dominant weak Unc).  Dominance of many alleles strongly enhanced by smg background. [Park and Horvitz 1986\; Johnsen and Baillie 1991\; TR]"	
"unc-71"	"III"	18.3007	"[C.elegansII] e541 : strong kinker, especially in reverse\; fairly active\; commissures sometimes on wrong side\; variable defects in axonal elongation and fasciculation\; synergizes with sem-5(n1779) to give Sem migration defect. ES3 ME2. OA1: ay7.YAC rescue (Y37D8)[McIntire et al. 1992\; Garriga and Stern 1994\; NG\; NH]"	
"unc-73"	"I"	-1.89945	"[C.elegansII] e936 : coiler, small and dumpyish, inactive\; commissures often on wrong side\; variable defects in axon growth and fasciculation\;occasional lineage defects\; reduced Z migration. Male copulatory spicules short and crumpled. Synergizes with sem-5(n1779) to give Sem migration defect.ES3 ME0. OA>3: rh40, ev454::Tc1,e936je3 (intragenic change, recessive lethal and dominant suppressor of e936). See also sup-39. Cloned: 7.7 and 7.3 kb transcripts, encodes >200 kD protein related to rho-type guanine nucleotide exchange factors, yeast CDC24. [McIntire et al. 1992\; Garriga and Stern 1994\; NJ\; JW\; NW]"	
"unc-74"	"I"	-1.46213	"[C.elegansII] e883 : weak kinker, slow, slightly small, resistant to 1 mM levamisole, sensitive to hypoosmotic shock\; L1 movement very poor, no backing. ES3 ME2. OA>25: x19 (resembles e883)\; etc. [Lewis et al. 1980\; ZZ]"	
"unc-75"	"I"	9.48302	"[C.elegansII] e950 : weak coiler especially in reverse\; moves forward well\; sluggish\; short\; Ric. ES3 ME2. OA2: h1041, h1042 (both lethal)[Brenner 1974\; Nguyen et al. 1995\; KR\; RM]"	
"unc-76"	"V"	7.05718	"[C.elegansII] e911pdi : inactive, tends to curl, dumpyish\; Egl-c\; amphid, phasmid, PDE, PVP, other axons abnormal\; dorsal extensions of DD and VD neurons frequently grow in abnormal directions, often fail to connect to dorsal nervecord. Defects in axonal elongation and fasciculation along nerve cords. ES3 ME0. NA1. Cloned: 1.8 kb transcripts, encode predicted 385 or 376 aa novel proteins.  Epitope-tagged UNC-76 detected in  axons. [Hedgecock et al. 1985\; McIntire et al. 1992\; MT]"	
"unc-77"	"IV"	1.92678	"[C.elegansII] e625 : irregular loopy movement both forward and reverse\; active\; thin\; sometimes protrusive vulva. Slight movement abnormality in e625\/+. ES2 ME2 NA1. [Brenner 1974]"	
"unc-78"	"X"	-9.46323	"[C.elegansII] e1217 : slow, abnormal body muscle birefringence, abnormal muscle ultrastructure with large aggregates of thin filaments\; suppressed to wildtype by sup-13. ES2 ME0. OA>5: e1221, st43 etc. [Waterston et al. 1980]"	
"unc-79"	"III"	-4.23156	"[C.elegansII] e1068 : irregular movement, somewhat sluggish (\"fainter\")\; hypersensitive to volatile anaesthetics.ES2 ME3. OA>5: e1031, e1291, e1510, ec1 etc. [Sedensky and Meneely 1987\; Morgan et al. 1991\; CW]"	
"unc-80"	"V"	18.7065	"[C.elegansII] e1272 : slightly sluggish, tends to pause (\"fainter\"), good movement\; hypersensitive to volatile anaesthetics.ES1 ME3. OA2: e1069, m513. [Sedensky and Meneely 1987\; Morgan et al. 1991\; CW]"	
"unc-81"	"III"	17.4855	"[C.elegansII] e1122 : slightly irregular movement. ES1 ME3. NA1. [CB\; ZZ]"	
"unc-82"	"IV"	2.57408	"[C.elegansII] e1220 : slow, good movement, abnormal reduced muscle birefringence\; abnormal body muscle ultrastructure with enlarged thick filaments\; weaker pharyngeal muscle abnormalities. ES2 ME2. OA>5: e1323, r194, st1323 etc. (all resemble e1220). [Waterston and Brenner 1980\; RW]"	
"unc-83"	"V"	-0.092956	"[C.elegansII] e1408ts : reverse kinker as adult, variably Egl\; L1 moves well\; variable failures in postembryonic migration of Pn nuclei into ventral cord and (some alleles) embryonic migrations of hyp-7 hypodermal nuclei\; all alleles are ts for Pn defect,non-ts for hyp-7 defect\; unmigrated Pn nuclei mostly fail to divide\; adult male phenotype variable, some can mate at 25C, all can mate at 15C. ES3 ME3 (15C). NA11: n331amb,ts, e1409amb,ts (suppressible only for hyp-7 defect), n159, n1218 etc. [Sulston and Horvitz 1981\; MH\; MT]"	
"unc-84"	"X"	13.4355	"[C.elegansII] e1410ts : reverse kinker as adult, L1 moves well\; variable failures in nuclear migrations : same phenotypes as unc-83(e1408). ES3 ME3 (15C). OA>10: e1174, e1748, n296, n1325 etc. (all alleles ts, resemble e1410). Complex complementation pattern\; null phenotype probably incompletely penetrant. Cloned: 2.5 kb and 3.5 kb transcripts (different 3' ends), latter encodes predicted 1100 aa protein with TM domain, similarity to fission yeast SPB-associated protein Sad. [Sulston and Horvitz 1981\; MH\; MT]"	
"unc-85"	"II"	-3.29689	"[C.elegansII] e1414amb : kinker in adult cannot back L1 moves well\; many postembryonic lineages abnormal as a result of defective cytokinesis in cell division\; all phenotypes similar to or slightly weaker than those of unc-59(e261). ES3 ME0. OA2: n319, n471. [Horvitz and Sulston 1980\; White et al. 1982\; MT]"	
"unc-86"	"III"	-0.335244	"[C.elegansII] eDf25 : pka e1416, lethargic\; Mec (touch cells absent)\; Egl (HSN cells fail to differentiate)\; non-chemotactic to NaCl\; lineage abnormalities involving reiterative divisions of neuroblasts, hence supernumerary neurons and missing neurons\; 2\% Him. ES3 ME2. OA>30: e1507 (Mec, Egl, non-Him, ME3). n848ts (superficially wildtype at 20C,  Mec and Egl at 25C), n306, n1132, n846 (amorph),u371::Tc3, rh1029::Tc3, n1351::Tc4,  etc. Alleles form graded series\; e1416\/Df is ME0\; Him alleles (e1416, n303 etc. are deletions of >15kb, affecting both unc-86 and him-15. Cloned: rare 1.9 kb transcript, encodes 467 aa POU-class homeoprotein.  Antibody staining indicates UNC-86 nuclear, specific to daughter nuclei affected by unc-86 mutations. Extensive promoter analysis.  See also him-15. [Chalfie et al. 1981\; Finney et al. 1988\; Finney and Ruvkun 1990\; GR]"	
"unc-87"	"I"	1.31429	"[C.elegansII] e1216 : limp paralysed or very sluggish\; somewhat Egl\; larvae more paralysed\; abnormal body muscle birefringence and ultrastructure, thin filaments in small bundles. ES3 ME0. OA>10: e1459amb (phenotype more severe than e1216), st39 r320 etc. Cloned: encodes predicted 40 kD protein with similarities to vertebrate smooth muscle proteins calponin, Drosophila mp20\; localized to I bands.  Alternative splicing. [Waterston et al. 1980\; Goetinck and Waterston 1994\;RW]"	
"unc-89"	"I"	-1.61706	"[C.elegansII] e1460 : good movement, slightly small, thin and transparent\; abnormal reduced birefringence in body wall and pharyngeal muscle\; thick filaments disarranged, no M-line. ES1 ME3. OA>10: st85amb, r291,ad539 (pka phm-1, worms small and starved, feeble pharyngeal contractions), e2338amb,st515::Tc1 etc. Cloned: encodes 750 kD protein related to UNC-22 (twitchin).  Antibodies stain middle of A bands. [Waterston et al. 1980\; GB]"	
"unc-90"	"X"	0.28119	"[C.elegansII] e1463sd: homozygotes small, rigidly paralysed (hypercontracted)\; mostly sterile (not viable)\; abnormal pharyngeal pumping abnormal muscle birefringence and ultrastructure\; Muscle hyperactivated, sticky pumping, short.Heterozygote e1463\/+ is slowish, somewhat dumpy\; muscle disorganization resembles homozyote but less severe. Suppressed semidominantly by lev-11(x12)\; also unc-54 null alleles are epistatic to e1463. ES3 (homozygote). NA1 (sd). Intragenic revertants of e1463  are wildtype (probable null phenotype). [Waterston et al. 1980\; JT\; RW]"	
"unc-93"	"III"	-5.4858	"[C.elegansII] e1500sd : adults paralysed, Egl\; slightly long\;abnormal muscle\; contract and relax when prodded (`rubber-band' phenotype). Muscle activation defective (flaccid, long).ES3 ME0. Poor mating in e1500\/+ males. Neomorphic allele, gf. OA1 (gf): n200(resembles e1500 but less severe phenotype).Both gf alleles suppressed by sup-9, sup-10,sup-11, sup-18. Also lf alleles: n392 (no phenotype alone but fails to complement e1500), n393 etc. Intragenic revertants of e1500 all have similar WT lf phenotype: e1500n234amb, des, e1500n200spo, e1500n243gri, e1500n1415::Tc1, etc.  OA>30 (ird). Cloned: 2.2 kb transcripts (slightly different 5'), encoding 700 and 705 aa predicted novel proteins with multiple (5-10) possible TM domains. [Greenwald and Horvitz 1980\; Levin and Horvitz 1992\;MT]"	
"unc-94"	"I"	0.798955	"[C.elegansII] su177 : slow, especially in adult\; abnormal patchy muscle birefringence and ultrastructure\; collections of thin and `intermediate' filaments (no staining with anti-intermediate filament antibodies). ES2 ME2. NA1. [Zengel and Epstein 1980\; HE]"	
"unc-95"	"I"	23.8823	"[C.elegansII] su106sd : very slow or paralysed, Egl\; abnormal variable muscle birefringence, disorganized sarcomeres with collections of thin filaments. ES3. OA3: su33amb  (similar phenotypes, ME0), etc. [Zengel and Epstein 1980\; HE]"	
"unc-96"	"X"	-18.1643	"[C.elegansII] su151 : very slightly slow, slightly Egl, moves well\; abnormal muscle birefringence and ultrastructure, collections of thin filaments near ends of cells. ES1 ME3. NA1. [Zengel and Epstein 1980\; HE]"	
"unc-98"	"X"	-1.69589	"[C.elegansII] su130 : slow somewhat Egl\; abnormal muscle birefringence and ultrastructure, collections of thin filaments, poorly organized A and I bands\; variable defects in neuroanatomy. ES2 ME1. NA1. [Zengel and Epstein 1980\; Siddiqui and Culotti 1991\;HE\; SQ]"	
"unc-100"	"I"	22.4877	"[C.elegansII] su149sd : slow, small, dumpyish\; male bursa swollen\; su149\/+ is slightly slow and small. ES3 ME0. OA2: su115 etc. [Zengel and Epstein 1980\; HE]"	
"unc-101"	"I"	13.3038	"[C.elegansII] m1des : coiler\; very sluggish, moves poorly\; slightly Egl\; slightly short\; defecation defects, abnormal FITC staining\; subviable.  Adult males have abnormal tails and spicules.OA>8: rh6, sy108, sy161, sy241.   Mutations suppress weak Vul mutants such as let-23(sy1)\; Muv phenotype in combination with sli-1. Cloned: encodes clathrin adaptor protein,ortholog of mouse AP47 (>75\% identity, AP47 can substitute for unc-101). [Lee et al. 1994\; DR\; PS]"	
"unc-103"	"III"	-4.05	"[C.elegansII] e1597sd : homozygote severe kinker, little movement\; slight Egl\; e1597\/+ somewhat less severe kinker. Muscle activation defective(flaccid, long).  Neomorphic (gf) allele.ES3 ME0. OA1 (gf): n500. Also intragenic revertants: e1597n1212spo(wildtype, probable null), e1597n1213, n500n1211 etc.  OA5 (ird). [Park and Horvitz 1986a\; JT\; MT]"	
"unc-104"	"II"	0.212607	"[C.elegansII] e1265 : severe coiler\; Ric\; defects in neuroanatomy\; poor response to dauer pheromone\;abnormal transport of synaptic vesicles. e1265\/Df probably lethal. ES3 ME0. OA>5: rh43(viable, severe), rh142 (sublethal), ut60 (lethal, arrest as coiler), ut104, e2184::Tc1,rh1016, rh1017.  Cloned: >30 kb gene, 6 kb transcript, encodes 1584 aa kinesin family protein. [Otsuka et al. 1991\; Hall and Hedgecock 1991\; Nguyen et al. 1995\; DD\; NJ]"	
"unc-105"	"II"	0.676507	"[C.elegansII] n490sd : small, hypercontracted, rigid paralytic\; very poor growth\; abnormal muscle structure. Muscle hyperactivated, sticky pumping, short.n490\/+ similar but less severe phenotype. Probable neomorphic gf allele.  Suppressed by mutations in unc-15, unc-22, unc-45, unc-54etc.  See also sup-20.ES3. OA2 (gf): n506 (less severe\; ME0), n1274. Also intragenic revertants: n490n804 (WT, no behavioral or muscular abnormality\; probable null phenotype), n490n820 etc. OA>10 (ird). Cloned: encodes degenerin family member,related to amiloride-sensitive Na channels. [Park and Horvitz 1986b\; MT\; RW]"	
"unc-108"	"I"	-1.94128	"[C.elegansII] n501dm : sluggish, poor backing. Similar phenotype in n501\/+. ES3. OA1: n777. Possibly haplo-insufficient locus. [Park and Horvitz 1986a]"	
"unc-109"	"I"	2.56499	"[C.elegansII] n499dm : recessive lethal, embryonic arrest\; n499\/+is uncoordinated, paralysed, muscle defective.  ES3.  NA1. [Park and Horvitz 1986a]"	
"unc-110"	"X"	0.411586	"[C.elegansII] e1913dm : recessive lethal\; e1913\/+ is uncoordinated thin, very sluggish, tends to shrink and relax when prodded, Egl\; exhibits muscle activation defects in some tissues, muscle hyperactivation in other tissues.  ES3.  NA1 (dm). Also intragenic revertant: e1913e2383 (WT, ME3). [CB\; JT]"	
"unc-112"	"V"	6.2	"[C.elegansII] r367 : adults paralysed and thin except for head region\; Egl\; disorganized body wall muscle, frayed myofilament lattice\; partial suppressor of unc-105(n490)\; young larvae nearly wild type (phenotypes very similar to unc-52). ES3 (adult) ME0. OA2: st562 (severe Pat (paralysed arrest at two-fold),some pharyngeal pumping), st581 (Pat).  Probable dense body component. [Williams and Waterston 1994\; DM\; TR\; RW]"	
"unc-115"	"X"	1.6928	"[C.elegansII] e2225mut : uncoordinated movement, severe kinker.  Muscle structure appears normal. OA1: mn481. Cloned: predicted protein has N-term LIMb domain, C-term villin headpiece similarity. [FF\; SP]"	
"unc-116"	"III"	-0.294398	"[C.elegansII] e2281::Tc5 : L1 coiler\; poor backing\; variable misplacement of axons, excretory canals. OA>3: e2282, e2310, pk211, rh24 (severe phenotype,high embryonic lethality at first cleavages\; abnormal membrane inventories, defective endocytosis, axon guidance defects). Cloned: encodes predicted 815 aa protein, extensive similarity to kinesin heavy chain. [Patel et al. 1993\; FF\; NJ\; UC]"	
"unc-119"	"III"	5.35957	"[C.elegansII] e2498::Tc1 : severe Unc, almost paralysed adults,dumpyish, tends to curl\; Daf-d, partial Egl, partial Dyf. Normal muscle ultrastructure.ES3.  ME0. OA3: ed3op, ed4oc, ed9 (all similar). Cloned: encodes predicted 219 aa novel protein. unc-119:GFP expressed extensively in axons. [Maduro & Pilgrim 1995]"	
"unc-120"	"I"	2.76524	"[C.elegansII] st364ts : progressive paralysis at 20C\; mature adults very sluggish at 15C\; number of thick and thin filaments variably reduced.  Sterile at 25C. [RW]"	
"unc-122"	"I"	26.3183	"[C.elegansII] e2520 :  medium coiler at all stages. Moves forward well when stimulated, tends to coil up when moving backwards or at rest. Coiling usually ventral, occasionally dorsal. ES2 ME1\/ME2. NA1. [CB]"	
"unc-123"	"III"	13.2681	"[C.elegansII] jd5sd : temperature-sensitive, semidominant, uncoordinated. When moving backwards coils dorsally, or moves in circles, dorsal aspect oriented centrally.  Almost WT at 15C. Possibly allelic with sup-1. NA1. Also revertant jd5jd10 (subtle movement defect, dominant suppressor of unc-17(e245)). [ER]"	
"unc-124"	"X"	-2.82284	"[C.elegansII] hs10cs : uncoordinated at 11C, kinker\;WT 23C\; phenotype reversible within hoursof temp shift, throughout development. Dominant interaction with some unc-7vt-4alleles.  NA1,[HH]"	
"unc-125"	"X"	-15.6751	"[C.elegansII] hs11cs,dm : uncoordinated (coiled, kinked,slow) at 11C\; WT at 23C\; phenotype reversible within minutes of temp shift, throughout development.  hs11\/+ similar. NA1. [HH]"	
"unc-126"	"III"	-0.413153	"[C.elegansII] hs12cs : severely paralysed at 11C, WT at23C\;  TSP early.  NA1. [HH]"	
"unc-127"	"V"	0.110357	"[C.elegansII] hs13cs : uncoordinated coiler at 11C, WTat 23C\; TSP early. NA1. [HH]"	
"unc-128"	"X"	8.34716	"[C.elegansII] rh110 : uncoordinated. Detected by extra neurons stained by monoclonal antibody M44 (normally stains only PVP), additional pair of neurons stain (? AVH or AVJ). No obvious axon outgrowth defects, very minor Mig defects. NA1. [NJ]"	
"unc-129"	"IV"	3.9979	"[C.elegansII] ev554: uncoordinated variable kinker\; axons grow inaberrant directions\; suppresses guidance defects caused by ectopic UNC-5. OA2: ev557, ev566. Cloned: cosmid rescue (C53D6). [NW]"	
"vab-1"	"II"	-3.44211	"[C.elegansII] e2 : notched head, variable dystrophy of ventral cephalic region, especially in L1\; penetrance < 70\%. ES3\/0 ME3. OA>10: e1063 (penetrance 35\%), e2027spo (penetrance > 90\%), e699 etc. [Brenner 1974\; Lewis and Hodgkin 1979\; CB\; CZ]"	
"vab-2"	"IV"	-2.3591	"[C.elegansII] e96 : notched head, especially in L1\; resembles vab-1 alleles\; penetrance 65\%. ES3\/0 ME3. OA3: e141, e1208 (penetrance 50\%), sy167. [Brenner 1974\; Lewis and Hodgkin 1979\; CB\; CZ]"	
"vab-3"	"X"	1.97666	"[C.elegansII] e648 : notched head, especially in L1\; 100\% penetrance, dystrophy of ventral head regions, disorganized hypodermal and anterior sensory anatomy\; non-chemotactic to NaCl\; Emo\; adult male tail variably deformed. ES3 ME0. OA8: e41, e1062 (resemble e648), e1178 (severe allele, 60\% larval lethal), e2429,sy66, sy281 (weak alleles) e1796 (pka lin-20, abnormal lineages for HO,H1, G1 and G2\; Mig defects in DTC). Cloned: encodes 455 aa predicted protein with paired domain, Pax6 homolog.  vab-3:GFP expressed in head precursors at 100 cell stage.See also mab-18. [Lewis and Hodgkin 1979\; Chisholm & Horvitz 1995\; CZ\; EM]"	
"vab-6"	"III"	-27.1487	"[C.elegansII] e697 : dumpyish, lumpy appearance, especially in L1\; sometimes twisted body. ES3 (L1) ME2. OA1: e1023 (resembles e697). [Hodgkin 1983\; CB]"	
"vab-7"	"III"	5.36885	"[C.elegansII] e1562 : hermaphrodite tail abnormal, sometimes twisted, tail whip never normal often bobbed\; variably uncoordinated with bent tail\; adult male tail deformed\; abnormal positioning of Cpap descendants, etc.ES3 ME0. NA>4: ???. Cloned: encodes homolog of Drosophila homeoprotein even-skipped.  Transcripts present in 4 posterior cells during gastrulation. [Hodgkin 1983\; CB\; NJ]"	
"vab-8"	"V"	3.66871	"[C.elegansII] e1017 : posterior half thin, pale, uncoordinated\; anterior half normal\; adult male tail anatomy vestigial\; failure of posterior migration of CAN cells\; rare animals have normal posterior morphology and one correctly placed CAN cell.Similar phenotypes in e1017\/Df. ES3 ME0. OA>5: ct33 (resembles e1017, sometimes abnormal HSN migration),ev411 (pka unc-107, slightly uncoordinated, partially shortened phasmidaxons. Unc phenotype enhanced byone or two doses of enu-1(ev419), ev411\; ev419 is severely uncoordinated, cannot back, very short phasmid axons). Multiple phenotypic classes\; some mutations affect only certain migrations. Cloned: multiple transcripts[Hedgecock et al. 1985\; JW, LK\; NG\; NJ\; NW]"	
"vab-9"	"II"	0.80007	"[C.elegansII] e1744 : slightly dumpy, tail whip knobbed at all stages except adult male (adult male tail tip slightly swollen)\; variably Egl. ES3 (larvae) ME2. OA2: e1775, e2016 (resemble e1744, slightly dumpier). [Hodgkin 1974]"	
"vab-10"	"I"	7.47732	"[C.elegansII] e698 : degenerate head, bent dorsally or ventrally\; penetrance 50\%\; generally poor growth\; adult male tail invariably thin fan and rays reduced in size\; Mua (defective muscle attachment). ES3\/1 ME0. NA1. [Hodgkin 1974\; NJ]"	
"vab-11"	"IV"	-10.053	"[C.elegansII] e1255 : tail variably blebbed or shortened in adult hermaphrodite.  ES2 (adult). [CB]"	
"xol-1"	"X"	-0.764221	"[C.elegansII] y9 : XO animals die as embryos or small crumpled feminized L1 larvae with disorganized cellular structures\; XX animals viable, apparently WT hermaphrodites.  Also enhances XX pseudomale phenotype of tra-2, tra-3, her-1(gf), to fertile mating male phenotype. 35-50 kb deletion null.OA>10: y70, y95, y138 (nonsense), mn467 (XOlethal but no XX Tra enhancement), e2533, e2583 etc. Cloned: multiple transcripts (1.5, 2.2, 2.5 kb) present 10x higher in XO than XX embryo\; encode novel predicted proteins with 3 different C-termini\; 2.2 kb transcript necessary and sufficient for xol-1 activity.Transgene overexpression leads to XX lethality. [Miller et al. 1988\; Rhind et al. 1995\; TY]"	
"zyg-1"	"II"	-1.95627	"[C.elegansII] b1ts,mm : L4 shift-up results in embryonic arrest at 2-20 nuclei\; first cleavage plane distorted, endomitosis. L1 shift-up results in abnormal gonadogenesis, Evl,Unc, weak Egl, Mab. Spindle formation defects. Viable at 16C. OA>5, complex phenotypes, most alleles only Mel: it4 (Mel, Evl), it25ts, it29, it37. Cloned: cosmid rescue (C08D10). [Wood et al. 1980\; Kemphues et al. 1988\; KK]"	
"zyg-2"	"I"	1.88299	"[C.elegansII] b10ts,mm : L4 shift-up results in embryonic arrest at <25-50 nuclei, early cleavage slow\; TSP before fertilization. L1 shift-up results in abnormal gonadogenesis, male sterility. Viable at 16C\; male fertility low at 16C. OA1: g57. [Wood et al. 1980\; Denich et al. 1984]"	
"zyg-3"	"II"	-2.06452	"[C.elegansII] b18ts,sd,mn : L4 shift-up results in embryonic arrest at >200 nuclei, eggs lyse in vitro. TSP short, during early cleavage. L1 shift-up results in abnormal gonadogenesis, male sterility. Viable at 16C. NA1. [Wood et al. 1980]"	
"zyg-7"	"III"	0.441863	"[C.elegansII] b187ts,mn : L4 shift-up results in embryonic arrest\; L1 shift-up results in some L4 arrest, males fertile. Viable at 16C.  NA1. [Wood et al. 1980]"	
"zyg-8"	"III"	14.6738	"[C.elegansII] b235ts,mnp : L4 shift-up results in embryonic arrest at >200 nuclei\; first cleavage abnormal giving 3 or 4 blastomeres\; phenotype paternally rescued by b235\/+ sperm cytoplasm. L1 shift-up results in viable adult, F1 embryonic arrest\; male sterility. Viable at 16C. NA1. [Wood et al. 1980]"	
"zyg-9"	"II"	0.790109	"[C.elegansII] b244ts : maternal effect embryonic lethal after larval shift-up\; meiotic and mitotic spindle abnormalities, defects in first mitotic divisions, like mei-1(gf), mel-26(gf).  OA>5: it3 (Mel, no zygotic rescue), b288ts,mm,b279, b301, b307. [Kemphues et al. 1988\; Mains et al. 1990\; HR\; KK]"	
"zyg-11"	"II"	0.625852	"[C.elegansII] mn40amb : maternal effect lethal, abnormal metaphase at meiosis II, symmetrical first cleavage, extensive early defects.  OA>5: b2ts (TSP before fertilization\; L1 shift-up Mel), it11ts, it1, it2 (weak), it28, it34 (mostly strict Mel), b290 (Mel, leaky, zygotic rescue). Cloned: transcripts not confined to germ line\; encodes novel protein. [Kemphues et al. 1988\; Carter et al. 1990\; KK]"	
"zyg-12"	"II"	-1.93934	"[C.elegansII] Putative single mutation in wild strain Bergerac, ts, mm : L4 shift-up results in embryonic arrest at >200 nuclei, normal early cleavages\; TSP before fertilization\; L1 shift-up results in abnormal gonadogenesis, male sterility.  Viable at 20C, 16C. NA1. [Wood et al. 1980]"	
"zyg-13"	"IV"	-27.9353	"[C.elegansII] b126 : [Wood et al. 1980]"